Interaction Checker

Print Friendly

Interaction Checker
Type in a drug name and select a result from the list.

Repeat the process to add multiple drugs.

When complete, press Enter to see the interactions.

Legend

No Known Interaction. Data have not demonstrated either pharmacodynamic or pharmacokinetic interactions between the specified agents
No Action Needed. Data demonstrate that the specified agents may interact with each other, but there is little to no evidence of clinical concern resulting from their concomitant use.
Monitor Therapy. Data demonstrate that the specified agents may interact with each other in a clinically significant manner. The benefits of concomitant use of these two medications usually outweigh the risks. An appropriate monitoring plan should be implemented to identify potential negative effects. Dosage adjustments of one or both agents may be needed in a minority of patients.
Consider Therapy Modification. Data demonstrate that the two medications may interact with each other in a clinically significant manner. A patient-specific assessment must be conducted to determine whether the benefits of concomitant therapy outweigh the risks. Specific actions must be taken in order to realize the benefits and/or minimize the toxicity resulting from concomitant use of the agents. These actions may include aggressive monitoring, empiric dosage changes, choosing alternative agents.
Avoid Combination. Data demonstrate that the specified agents may interact with each other in a clinically significant manner. The risks associated with concomitant use of these agents usually outweigh the benefits. These agents are generally considered contraindicated.

Our drug interaction checker provides interactions between medications with three levels of severity.

The RxISK interaction checker only covers medications marketed in North America. For other medications be sure and check local sources.