What is PSSD? Post-SSRI sexual dysfunction (PSSD) is an iatrogenic condition in which sexual function does not return to normal after the discontinuation of serotonin reuptake inhibiting antidepressants.1 This group includes: Commonly used SSRIs include: Common SNRIs include: Most people who take an SSRI or related medication will feel some degree of genital numbing, often … Continue reading Post-SSRI Sexual Dysfunction (PSSD)