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Drug:

Reaction: PRURITUS

20260101 - 20261231

No. 1 - 100

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No.
safetyreportid
occurcountry
patientonsetage
patientsex 1:M 2:F
Adverse reaction
Drug (openfda.generic_name, medicinalproduct)
1
26555316
US
Pruritus, Urticaria, Drug ineffective,
OMALIZUMAB,
2
26555445
AR
 67 1
Urticaria, Pruritus, Rash, Acne pustular, Dry skin, Epistaxis, Skin fissures, Miliaria, Perioral dermatitis, Sensitive skin, Skin burning sensation, Erythema, Lip dry, Skin disorder, Off label use,
PANITUMUMAB, PANITUMUMAB, PANITUMUMAB, PANITUMUMAB,
3
26555447
US
 60 1
Cerebrovascular accident, Pruritus,
RISANKIZUMAB-RZAA,
4
26555605
US
 46 2
Erythema, Dyspnoea, Pruritus, Injection site pruritus, Injection site erythema,
TIRZEPATIDE,
5
26555648
CA
 86 2
Blood creatinine increased, Pruritus, Rash,
PANTOPRAZOLE, APIXABAN, BISOPROLOL FUMARATE, CALCIUM CARBONATE, ANTACID, CANDESARTAN, VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE, ERGOCALCIFEROL, POLYETHYLENE GLYCOL, LEVOTHYROXINE SODIUM,
6
26555886
US
Pruritus, Hypersensitivity, Drug ineffective,
PRABOTULINUM TOXIN TYPE A,
7
26556074
AR
 66 2
Anal incontinence, Rectal haemorrhage, Hepatitis, Skin burning sensation, Swollen tongue, Mouth swelling, Eating disorder, Pain, Rash, Pruritus, Exfoliative rash, Decreased immune responsiveness, Colostomy bag user, Acne pustular, Ill-defined disorder, Rash macular, Erythema, Blister, Malaise, Discomfort, Skin haemorrhage, Dysarthria, Drug ineffective, Dry skin, Off label use, Drug hypersensitivity, Flatulence, Blood test abnormal, Magnetic resonance imaging abnormal, Therapy interrupted, Musculoskeletal pain,
PANITUMUMAB, PANITUMUMAB, PANITUMUMAB, PANITUMUMAB,
8
26556132
CA
 74
Spinal disorder, Drug intolerance, Asthenia, Dizziness, Pruritus, Nausea, Drug ineffective,
ADALIMUMAB, ADALIMUMAB-AATY, ADALIMUMAB-ADAZ, ADALIMUMAB-FKJP, ADALIMUMAB, ADALIMUMAB-AATY, ADALIMUMAB-ADAZ, ADALIMUMAB-FKJP, RITUXIMAB, RITUXIMAB, ADALIMUMAB-ADAZ, METHOTREXATE, METHOTREXATE SODIUM, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, DIPHENHYDRAMINE, DIPHENHYDRAMINE HYDROCHLORIDE, METHYLPREDNISOLONE,
9
26556190
US
Eye swelling, Pruritus,
PRABOTULINUM TOXIN TYPE A,
10
26556487
US
 59 2
Condition aggravated, Pruritus, Arthralgia, Myalgia, Ulcer,
DASATINIB,
11
26556666
US
 32
Hypoaesthesia, Paraesthesia, Pruritus, Contusion, Influenza like illness,
PRABOTULINUM TOXIN TYPE A,
12
26556688
CA
 63 2
Alopecia, Application site reaction, Chronic spontaneous urticaria, Depression, Dyspnoea, Dyspnoea exertional, Haemorrhage, Headache, Hepatic enzyme increased, Urticaria, Tachycardia, Insomnia, Intervertebral disc protrusion, Malaise, Middle insomnia, Muscular weakness, Pain, Paraesthesia, Primary biliary cholangitis, Pruritus, Scratch, Skin burning sensation, Skin lesion, Skin plaque, Spinal meningeal cyst, Stress, Erythema, Product dose omission issue, Drug ineffective, Incorrect dose administered, Inappropriate schedule of product administration, Wrong technique in product usage process,
OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, NICOTINE, NICOTINE POLACRILEX, NICOTINE POLACRILEX MINI, NICOTINE POLARILEX,
13
26556731
CA
 2
Feeling abnormal, Gait inability, Movement disorder, Drug hypersensitivity, Injection site pain, Erythema, Myalgia, Insomnia, Cough, Gait disturbance, Nasopharyngitis, Pruritus,
VANCOMYCIN HYDROCHLORIDE, VANCOMYCIN, CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CIPROFOLXACIN, CIPROFLOXACIN TABLETS, OCTREOTIDE ACETATE, OCTREOTIDE ACETATE, OCTREOTIDE ACETATE, OCTREOTIDE ACETATE, OCTREOTIDE ACETATE, OCTREOTIDE ACETATE,
14
26556858
US
 61 2
Pruritus,
TRALOKINUMAB-LDRM,
15
26556944
US
 38 2
Pruritus, Sleep disorder, Skin fissures, Blister, Dry skin, Skin exfoliation,
DUPILUMAB,
16
26556949
US
 49 2
Pruritus, Inappropriate schedule of product administration,
DUPILUMAB,
17
26556951
US
 44 2
Pruritus, Rash,
DUPILUMAB,
18
26557139
AR
 65 2
Metastases to liver, Post procedural complication, Colon operation, Nasal discomfort, Feeling cold, Muscle spasms, Blister, Diarrhoea, Nausea, Dry skin, Nail disorder, Feeling hot, Pruritus, Gastrointestinal disorder, Vision blurred, Sneezing, Onychomadesis, Skin haemorrhage, Rhinitis, Skin laceration, Sensory loss, Retching, Limb injury, Impaired healing, Temperature intolerance, Loss of personal independence in daily activities, Pain in extremity, Nasal dryness, Cough, Epistaxis, Skin fissures, Rash, Localised infection, Acne, Erythema, Drug ineffective, Muscle spasms,
PANITUMUMAB, OXALIPLATIN, OXALIPLATIN,
19
26557157
US
 2
Paraesthesia, Pruritus, Rash pruritic,
ALIROCUMAB,
20
26557159
US
 22 2
Urticaria, Pruritus, Swelling, Product use in unapproved indication,
DUPILUMAB,
21
26557163
US
 41 2
Pruritus, Skin haemorrhage,
DUPILUMAB,
22
26557165
US
 66 1
Pruritus,
DUPILUMAB,
23
26557166
US
 29 2
Eczema, Pruritus,
DUPILUMAB,
24
26557168
US
 2 1
Dry skin, Skin haemorrhage, Sleep disorder due to a general medical condition, Pruritus, Product dose omission issue,
DUPILUMAB,
25
26557170
US
 46 1
Pruritus, Product dose omission in error,
DUPILUMAB, DUPILUMAB,
26
26557181
US
 2
Pruritus, Urticaria, Product use in unapproved indication,
DUPILUMAB,
27
26557184
US
 4 1
Dry skin, Pruritus, Injection site reaction,
DUPILUMAB,
28
26557243
US
 58 2
Eczema, Pruritus, Sleep disorder due to a general medical condition, Dry skin, Skin exfoliation, Injection site bruising,
DUPILUMAB,
29
26557288
CA
 38 2
Ear pruritus, Inappropriate schedule of product administration, Off label use, Pruritus, Throat irritation,
RITUXIMAB, RITUXIMAB, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, DIMENHYDRINATE, METHYLPREDNISOLONE, METHYLPREDNISOLONE,
30
26557295
CN
 62 2
Urticaria, Pruritus, Rash,
FRUQUINTINIB,
31
26557317
US
 88 1
Pruritus, Skin swelling,
DUPILUMAB,
32
26557332
US
 11 1
Pruritus, Sleep disorder, Dry skin, Skin haemorrhage, Skin weeping, Feeling hot, Hyperhidrosis,
DUPILUMAB,
33
26557399
US
 39 1
Pruritus,
DUPILUMAB,
34
26557421
US
 69 1
Rash macular, Pruritus, Skin burning sensation, Condition aggravated, Product use in unapproved indication,
DUPILUMAB,
35
26557436
US
 71 1
Pruritus, Macule,
DUPILUMAB,
36
26557447
US
 80 1
Pruritus,
DUPILUMAB, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, FLUTICASONE FUROATE, UMECLIDINIUM BROMIDE AND VILANTEROL TRIFENATATE, METHYLPHENIDATE HYDROCHLORIDE, ALBUTEROL SULFATE,
37
26557465
US
 2
Pruritus,
DUPILUMAB,
38
26557473
US
 2
Dry skin, Pruritus,
DUPILUMAB, AMLODIPINE BESYLATE, HYDROCHLOROTHIAZIDE, ROSUVASTATIN CALCIUM, ALBUTEROL SULFATE,
39
26557541
US
 2
Discomfort, Rash, Pruritus, Pain, Product dose omission issue, Sleep disorder due to a general medical condition,
DUPILUMAB, DUPILUMAB,
40
26557545
US
 31 1
Pruritus,
DUPILUMAB,
41
26557549
US
 58 2
Psoriasis, Dermatitis, Dermatitis psoriasiform, Pruritus,
DUPILUMAB,
42
26557552
US
 30 2
Dry skin, Pruritus,
DUPILUMAB,
43
26557560
US
 2
Pruritus,
DUPILUMAB,
44
26557588
US
 62 1
Dermatitis atopic, Eczema, Skin exfoliation, Pruritus, Inappropriate schedule of product administration,
DUPILUMAB,
45
26557598
US
 64 2
Dyspnoea, Product dose omission issue, Pruritus,
DUPILUMAB,
46
26557617
US
 21 2
Pharyngitis streptococcal, Dry skin, Pruritus,
DUPILUMAB,
47
26557618
US
 25 2
Pruritus,
DUPILUMAB,
48
26557631
US
 11 1
Dry skin, Pruritus, Therapeutic response decreased,
DUPILUMAB,
49
26557831
US
 2
Hepatic enzyme increased, Pruritus,
GUSELKUMAB,
50
26557977
US
 32 2
Dermatitis atopic, Pruritus, Product dose omission issue,
DUPILUMAB, DUPILUMAB, TRIAMCINOLONE ACETONIDE, TRIAMCINOLONE ACETONIDE OINTMENT USP, 0.05%,
51
26558046
US
Rash, Dermatitis, Pruritus,
NEMOLIZUMAB-ILTO,
52
26558050
US
 41 2
Skin ulcer, Fatigue, Eczema, Pruritus, Skin fissures, Skin exfoliation, Dry skin, Sleep disorder due to a general medical condition, Skin haemorrhage, Skin weeping,
DUPILUMAB, BUPROPION, BUSPIRONE HYDROCHLORIDE, ACETAMINOPHEN, ASPIRIN AND CAFFEINE, ACETAMINOPHEN, ASPIRIN, CAFFEINE, TURMERIC, CURCUMA AROMATICA ROOT, INDIAN FRANKINCENSE, GINGER, FEVERFEW, IBUPROFEN, TRIAMCINOLONE ACETONIDE, TRIAMCINOLONE ACETONIDE OINTMENT USP, 0.05%, UBROGEPANT,
53
26558061
US
 1
Pruritus, Dermatitis atopic, Product dose omission issue,
DUPILUMAB, WATER, ACONITUM NAP, ARSENICUM ALB, BORAX, CALC PHOS, GELSENIUM, LYCOPODIUM, PHOSPHORICUM AC, PICRICUM AC, PLUMB MET, SOLIDAGO, FLUTICASONE PROPIONATE,
54
26558076
US
 2
Pruritus,
DUPILUMAB, AMLODIPINE BESYLATE, ATORVASTATIN CALCIUM, ATORVASTATIN CALCIUM, FILM COATED, LOSARTAN POTASSIUM, LOSARTAN,
55
26558077
CN
 67 1
Burning sensation, Conjunctival hyperaemia, Flushing, Swelling face, Rash erythematous, Pruritus,
IOHEXOL,
56
26558078
US
 2
Pruritus, Product dose omission issue,
DUPILUMAB,
57
26558079
CN
 42 1
Vitreous floaters, Pruritus, Contrast media reaction,
IODIXANOL, IODIXANOL,
58
26558081
US
 64 2
Dry skin, Eye pruritus, Skin exfoliation, Pruritus,
DUPILUMAB, GALCANEZUMAB-GNLM, ESTRADIOL, ESTRADIOL GEL 0.1%, ESTRADIOL TRANSDERMAL, ESTRADIOL,, IBUPROFEN, ESOMEPRAZOLE MAGNESIUM, OMEPRAZOLE MAGNESIUM, RIZATRIPTAN,
59
26558136
US
 72 2
Pruritus, Skin exfoliation,
DUPILUMAB, ALENDRONATE SODIUM, GABAPENTIN, HYDROCHLOROTHIAZIDE, LOSARTAN POTASSIUM, LOSARTAN, VITAMIN C, ERGOCALCIFEROL, ZINC, ZINC GLUCONATE, ZINC CHLORIDE,
60
26558145
US
 29 2
Dermatitis, Pruritus, Drug ineffective for unapproved indication, Drug ineffective for unapproved indication,
DUPILUMAB, LEBRIKIZUMAB-LBKZ, PIMECROLIMUS,
61
26558146
US
 72 2
Dermatitis atopic, Pruritus, Dry skin, Skin exfoliation, Intentional product misuse,
DUPILUMAB, DUPILUMAB, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, ATORVASTATIN CALCIUM, ATORVASTATIN CALCIUM, FILM COATED, ESTRADIOL, ESTRADIOL GEL 0.1%, ESTRADIOL TRANSDERMAL, ESTRADIOL,, LEVOTHYROXINE SODIUM, LEVOTHYROXINE SODIUM ANHYDROUS, LEVOTHYROXINE SODIUM, LEVOTHYROXINE SODIUM ANHYDROUS, PSYLLIUM HUSK, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, LEVOTHYROXINE SODIUM, LEVOTHYROXINE SODIUM ANHYDROUS, ESTRADIOL, ESTRADIOL GEL 0.1%, ESTRADIOL TRANSDERMAL, ESTRADIOL,,
62
26558394
CN
 78 2
Anaphylactic shock, Eyelid oedema, Conjunctival oedema, Erythema, Pruritus, Chest discomfort, Tachypnoea, Dizziness, Blood pressure decreased, Heart rate increased, Dyspnoea, Rash,
TOBRAMYCIN,
63
26558811
US
 56 1
Headache, Dry skin, Rash, Pruritus,
TRALOKINUMAB-LDRM,
64
26558848
US
 18
Eczema herpeticum, Pain of skin, Skin burning sensation, Pruritus, Eczema, Rash,
NEMOLIZUMAB-ILTO, NEMOLIZUMAB-ILTO, DUPILUMAB, UPADACITINIB,
65
26559152
US
 2
Urine output decreased, Decreased appetite, Pain, Pruritus, Headache, Peripheral swelling, Peripheral swelling, Joint swelling, Infusion site discharge,
66
26559224
EU
 58 2
Palmar-plantar erythrodysaesthesia syndrome, Head discomfort, Pruritus, Palpitations, Skin burning sensation, Abdominal pain, Vomiting,
SEMAGLUTIDE, ENALAPRIL, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG,
67
26559230
CA
 45 2
Abdominal discomfort, Arthralgia, Autoimmune disorder, Blood cholesterol increased, Confusional state, Contusion, Decreased appetite, Deep vein thrombosis postoperative, Drug ineffective, Eye injury, Folliculitis, Gait inability, Gastrointestinal disorder, Headache, Helicobacter infection, Hypertension, Hypoaesthesia, Ill-defined disorder, Impaired healing, Incorrect route of product administration, Infection, Irritable bowel syndrome, Liver disorder, Lower respiratory tract infection, Lupus vulgaris, Maternal exposure during pregnancy, Muscle injury, Musculoskeletal stiffness, Nasopharyngitis, Nausea, Pemphigus, Peripheral swelling, Off label use, Pruritus, Rash, Rheumatic fever, Rheumatoid factor positive, Swelling, Swollen joint count increased, Synovitis, Systemic lupus erythematosus, Vomiting, Wheezing, Wound,
TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, RITUXIMAB,
68
26559232
US
 2
Dizziness, Feeling abnormal, Pruritus, Pyrexia, Nausea, Rash,
DOXYCYCLINE, DOXYCYCLINE HYCLATE,
69
26559363
RU
 56 2
Pruritus, Blood glucose fluctuation,
INSULIN ASPART INJECTION, INSULIN ASPART, LOSARTAN, LEVOTHYROXINE SODIUM, LEVOTHYROXINE SODIUM ANHYDROUS, ATENOLOL, GABAPENTIN, EZETIMIBE,
70
26559506
US
Rash, Pruritus,
PRABOTULINUM TOXIN TYPE A,
71
26559858
56 1
Contrast media allergy, Tachypnoea, Blood pressure decreased, Loss of consciousness, Unresponsive to stimuli, Pulse absent, Apnoea, Oxygen saturation immeasurable, Heart rate abnormal, Pruritus, Dyspnoea, Cyanosis, Conjunctival oedema, Chest discomfort, Erythema, Supraventricular extrasystoles,
IOPROMIDE, IOPROMIDE,
72
26559916
US
 58 2
Hypersensitivity, Rash, Erythema, Swelling, Skin disorder, Pruritus,
INCLISIRAN, INCLISIRAN,
73
26559994
US
 48
Rash, Pruritus,
NEMOLIZUMAB-ILTO, NEMOLIZUMAB-ILTO, NEMOLIZUMAB-ILTO,
74
26560016
US
 76 1
Pruritus,
LENALIDOMIDE, LENALIDOMIDE, LENALIDOMIDE, LENALIDOMIDE,
75
26560039
Contrast media reaction, Pruritus, Erythema,
GADOTERIDOL,
76
26560092
2
Rash, Pruritus, Dizziness,
IRON SUCROSE, IRON SUCROSE,
77
26560112
US
 2
Pruritus, Skin haemorrhage, Scratch,
DUPILUMAB, DUPILUMAB,
78
26560119
US
 2
Cerebrovascular accident, Seizure, Pruritus,
DUPILUMAB,
79
26560122
US
 75 1
Pruritus, Therapeutic response decreased,
DUPILUMAB, ACARBOSE, LOSARTAN POTASSIUM, LOSARTAN, METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, ROSUVASTATIN, TAMSULOSIN HYDROCHLORIDE,
80
26560125
US
 59 1
Pruritus, Therapeutic response shortened,
DUPILUMAB, DUPILUMAB,
81
26560221
US
 74 1
Rash erythematous, Pruritus, Skin burning sensation,
DUPILUMAB,
82
26560229
US
 23 2
Rash erythematous, Pruritus, Burning sensation, Condition aggravated, Product use in unapproved indication,
DUPILUMAB,
83
26560241
US
 17 1
Hypersensitivity, Pruritus, Product dose omission issue,
DUPILUMAB,
84
26560247
US
 66 1
Rash erythematous, Skin burning sensation, Pruritus, Product use in unapproved indication,
DUPILUMAB, DUPILUMAB,
85
26560250
US
 67 2
Dry skin, Pruritus,
DUPILUMAB,
86
26560252
US
 54 1
Rash, Pruritus, Skin burning sensation, Product use in unapproved indication,
DUPILUMAB, DUPILUMAB,
87
26560265
US
 66 2
Dyspnoea, Pruritus,
DUPILUMAB, DUPILUMAB,
88
26560269
US
 82 2
Sleep disorder, Skin fissures, Skin exfoliation, Dry skin, Pruritus,
DUPILUMAB, GARLIC, LOSARTAN POTASSIUM, LOSARTAN, CETIRIZINE HYDROCHLORIDE, POLYETHYLENE GLYCOL 3350, DULOXETINE HYDROCHLORIDE, DULOXETINE, MONTELUKAST SODIUM, GABAPENTIN, CONJUGATED ESTROGENS, ESTROGENS, CONJUGATED, ISOSORBIDE MONONITRATE, PITAVASTATIN CALCIUM, FOLIC ACID, LEVOTHYROXINE SODIUM, METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, EPINEPHRINE, TRIAMCINOLONE ACETONIDE, TRIAMCINOLONE ACETONIDE OINTMENT USP, 0.05%, AMMONIUM LACTATE,
89
26560272
US
 50 1
Eczema, Skin irritation, Pruritus, Rash,
DUPILUMAB, DUPILUMAB, UPADACITINIB,
90
26560274
US
 59 2
Pruritus,
DUPILUMAB,
91
26560275
US
 88 1
Pruritus,
DUPILUMAB,
92
26560287
US
 55 1
Rash macular, Pruritus, Eczema, Skin burning sensation,
DUPILUMAB,
93
26560293
US
 2
Pruritus,
DUPILUMAB,
94
26560294
US
 50 1
Eczema, Pruritus, Rash, Skin discolouration, Product dose omission in error, Incorrect dose administered,
DUPILUMAB,
95
26560323
US
 35 1
Rash erythematous, Pruritus, Skin burning sensation, Condition aggravated,
DUPILUMAB, DUPILUMAB, SECUKINUMAB,
96
26560325
US
 88 1
Wheezing, Pruritus,
DUPILUMAB, ALBUTEROL SULFATE, ALBUTEROL, AMLODIPINE, ATORVASTATIN CALCIUM, ATORVASTATIN CALCIUM, FILM COATED, NEBIVOLOL, NEBIVOLOL HYDROCHLORIDE, RIVAROXABAN,
97
26560341
US
 33 1
Dry skin, Eyelid skin dryness, Pruritus, Erythema,
DUPILUMAB, DUPILUMAB, DUPILUMAB,
98
26560343
US
 56 2
Dyshidrotic eczema, Pruritus, Skin irritation, Product use in unapproved indication,
DUPILUMAB,
99
26560367
US
 1
Rash erythematous, Pruritus, Product dose omission issue,
DUPILUMAB,
100
26560373
US
 75 2
Rash erythematous, Pruritus, Skin burning sensation, Dry skin, Peripheral swelling, Product use in unapproved indication,
DUPILUMAB,

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last_updated

2026-04-28

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