




RxISK is a free, independent drug safety website to help you weigh the benefits of any medication against its potential dangers.
All drugs have side effects, but people often don’t link the effect they are experiencing to starting, stopping, or changing the dose of a drug. RxISK provides free access to information and tools to help you assess the connection between a drug and a side effect.
![]() |
![]() |
![]() |
![]() |
Drug search | Lifesaving checklist |
Interaction checker |
Guides & papers |
![]() |
![]() |
![]() |
![]() |
Too many drugs? |
Complex withdrawal |
Glossary | Post-SSRI sexual dysfunction |
PSSD Research Fund
Your donations are needed to fund scientific research into post-SSRI sexual dysfunction (PSSD) and other enduring sexual dysfunctions. The aim is to better understand the biology of these conditions and hopefully find treatments.
This post came from a regular contributor to RxISK and DH posts. An earlier comment pointed to something interesting and has developed into this post which should be of interest to anyone who has a withdrawal problem that entails some kind of akathisia. When I came out of a psychiatric hospital in Summer 2019, I […]
Being Hooked to and having to Withdraw from Antidepressants, especially any that act on the serotonin system, is one of the greatest public health issues of our day. Close to 15 per cent of the population of most Western countries are affected. Peter Groot and colleagues in the Netherlands have done more than anyone to […]
This weeks post was supposed to be just about Sexual Mysteries. What’s in a Touch? As it was waiting to be posted, a controversy blew up about the International Society of Sexual Medicine and claims by Dr Anita Clayton that there is no such thing as PSSD. There did not seem to be enough for […]
This is an important post for anyone hunting for a test for PSSD. If the CT fibres mentioned here are not fibres that show up distinctly on either skin biopsy or CCM, then these tests may not pick up a very real problem. We need some research on whether CT fibres show around the ankle […]
A brief recap In October 2022, we ran a blog post aimed at recruiting patients in the UK with post-SSRI sexual dysfunction (PSSD) who could be tested for small fibre neuropathy. This was to be done by skin biopsy which is the standard method for investigating the condition. The project was in response to information […]