No one knows a prescription drug’s side effects like the person taking it.
Make your voice heard.
RxISK is a free, independent drug safety website to help you weigh the benefits of any medication against its potential dangers.
Could it be my meds?
All drugs have side effects, but people often don’t link the effect they are experiencing to starting, stopping, or changing the dose of a drug. RxISK provides free access to information and tools to help you assess the connection between a drug and a side effect.
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Post-SSRI Sexual Dysfunction
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Our free Healthcare Record Pro Forma is a one page document that you can complete with details of your problem together with an official SNOMED code, and then give it to your doctor.
Explore our RxISK Zones
The RxISK Zones bring together a collection of content from our website about each type of side effect. They are aimed at giving you a good overview of the issue without having to search through lots of material.
Our zones cover suicide, violence, sex and relationships, hair, skin and nails, withdrawal, vision, and fertility.
Are you experiencing a drug side effect?
Get your free RxISK Report to find out
The RxISK Report takes 10 minutes to complete and provides you with a RxISK Score indicating how likely it is that your problem is caused by starting or stopping a prescription drug.
PSSD Research Fund
Your donations are needed to fund scientific research into post-SSRI sexual dysfunction (PSSD) and other enduring sexual dysfunctions. The aim is to better understand the biology of these conditions and hopefully find treatments.
From The Blog…
Isotretinoin and Safety – Destiny or Mirage?
On January 22, Britain’s Medicines Regulator convened a meeting on consent to Isotretinoin (Accutane, Claravis), whose dynamics map straight onto Prima Facie. Families whose children died from Isotretinoin triggered suicide, or whose sexual function is potentially wiped our forever have clamored for reform for over a decade. In 2023, MHRA rewrote the Rules of Evidence…
Continue Reading Isotretinoin and Safety – Destiny or Mirage?
Guilty Until Proven Innocent – Prima Facie
https://www.youtube.com/watch?v=tOQ7YsxkVUQ Prima Facie – on the face of it – it is clear who the legally guilty party is – until (perhaps) it is proven otherwise. Prima Facie is a play by Suzie Miller. She tells the story behind it and the changes to the law around sexual assault it has brought about, along with…
Are HealthCare and Science Compatible?
MEDICAL CARE MEDICAL SCIENCE This talk was given at the request of Professor Ilana Crome to healthcare staff and students linked to the UK’s Midland’s Partnership University on January 12, 2026. Slide 1: In the US, the term medical model translates to a pharmaceutical, model – a giving meds model. The term medical model began…