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Post-SSRI Sexual Dysfunction Literature

Below is a list of academic literature involving post-SSRI sexual dysfunction (PSSD). Articles marked with an asterisk (*) are available in full.

2023

Giatti S, Diviccaro S, Cioffi L, Cosimo Melcangi R. *POST-FINASTERIDE SYNDROME AND POST-SSRI SEXUAL DYSFUNCTION: TWO CLINICAL CONDITIONS APPARENTLY DISTANT, BUT VERY CLOSE. Frontiers in Neuroendocrinology.

Marks S. A clinical review of antidepressants, their sexual side-effects, post-SSRI sexual dysfunction, and serotonin syndrome. British Journal of Nursing.

C Pukall. *(020) Post-SSRI/SNRI Sexual Dysfunction: A review. The Journal of Sexual Medicine.

Ben-Sheetrit J, Hermon Y, Birkenfeld S, Gutman Y, Csoka AB, Toren P. *Estimating the risk of irreversible post-SSRI sexual dysfunction (PSSD) due to serotonergic antidepressants. Annals of General Psychiatry.

Panek E, Jasłowski D, Rzeszutko M, Raczkiewicz P, Panasiuk D, Skrętowicz M, Szponarowicz P, Snopkowski B, Korzec T, Sosnowski J. *Post-SSRI sexual dysfunction and SSRI induced sexual dysfunction – literature review. Journal of Education, Health and Sport.

Klaas S, Siva JB, Bak M, Govers M, Schreiber R. *The pathophysiology of Post SSRI Sexual Dysfunction – Lessons from a case study. Biomedicine & Pharmacotherapy.

2022

De Luca R, Bonanno M, Manuli A, Calabrò RS. *Cutting the First Turf to Heal Post-SSRI Sexual Dysfunction: A Male Retrospective Cohort Study. Medicines.

Achour V, Masson M, Lancon C, Boyer L, Fond G. Screening and treatment of Post-Selective Serotonin Reuptake Inhibitors sexual dysfunctions. Encephale.

Reisman Y, Jannini TB, Jannini EA. *Post-Selective Serotonin Reuptake Inhibitor Sexual Dysfunctions (PSSD): Clinical Experience with a Multimodal Approach. Journal of Men’s Health.

2021

Chinchilla Alfaro K, van Hunsel F, Ekhart C. Persistent sexual dysfunction after SSRI withdrawal: a scoping review and presentation of 86 cases from the Netherlands. Expert Opinion on Drug Safety.

Healy D, Bahrick A, Bak M, Barbato A, Calabrò RS, Chubak BM, et al. *Diagnostic criteria for enduring sexual dysfunction after treatment with antidepressants, finasteride and isotretinoin. International Journal of Risk & Safety in Medicine.

Studt A, Gannon M, Orzel J, Vaughan A, Pearlman AM. Charactarizing Post-SSRI sexual dysfunction and its impact on quality of life through an international online survey. International Journal of Risk & Safety in Medicine.

Patacchini A, Cosci F. Exposure to serotonin selective reuptake inhibitors or serotonin noradrenaline reuptake inhibitors and sexual dysfunction: Results from an online survey. International Journal of Risk & Safety in Medicine.

Giatti S, Diviccaro S, Cioffi L, Falvo E, Caruso D, Melcangi RC. Effects of paroxetine treatment and its withdrawal on neurosteroidogenesis. Psychoneuroendocrinology.

2020

Raj S. *Post-SSRI Sexual Dysfunction: Exploration of the Sexual Domains and Symptoms. Master thesis (Clinical Psychology), Utrecht University.

Waraich A, Clemons C, Ramirez R, Yih J, Goldstein S, Goldstein I. *Post-SSRI sexual dysfunction (PSSD): Ten year retrospective chart review. The Journal of Urology.

Rothmore J. Antidepressant-induced sexual dysfunction. The Medical Journal of Australia.

Reisman Y. Post-SSRI sexual dysfunction. The BMJ.

Healy D. *Antidepressants and sexual dysfunction: a history. Journal of the Royal Society of Medicine.

Lorenz TK. Antidepressant Use During Development May Impair Women’s Sexual Desire in Adulthood. The Journal of Sexual Medicine.

Patacchini A, Cosci F. A Paradigmatic Case of Postselective Serotonin Reuptake Inhibitors Sexual Dysfunction or Withdrawal After Discontinuation of Selective Serotonin Reuptake Inhibitors? Journal of Clinical Psychopharmacology.

2019

Lüning C. *Life after antidepressants: Does persisting sexual dysfunction influence quality of life? Master Thesis (Clinical Psychology), Utrecht University.

Healy D, LaPalme J, Levin M. Post-SSRI Sexual Dysfunction: A Bioelectric Mechanism? Bioelectricity.

Reisman Y. Are There Any Sex/Gender Differences in Post-Selective Serotonin Reuptake Inhibitors (SSRI) Sexual Dysfunction (PSDD)? Current Sexual Health Reports.

Healy D. *Post-SSRI sexual dysfunction & other enduring sexual dysfunctions. Epidemiology and Psychiatric Sciences.

Healy D, Le Noury J, Mangin D. Post-SSRI sexual dysfunction: Patient experiences of engagement with healthcare professionals. International Journal of Risk & Safety in Medicine. [See the full manuscript]

Calabrò RS, De Luca R, Manuli A, Portaro S, Naro A, Quattrini F. Towards Improving Post-SSRI Sexual Dysfunction by Using Nutriceuticals: Lessons from a Case Study. Journal of Sex & Marital Therapy.

2018

Healy D. *Citizen petition: Sexual side effects of SSRIs and SNRIs. International Journal of Risk & Safety in Medicine.

Healy D, Le Noury J, Mangin D. *Enduring sexual dysfunction after treatment with antidepressants, 5α-reductase inhibitors and isotretinoin: 300 cases. International Journal of Risk & Safety in Medicine.

Giatti S, Diviccaro S, Panzica G, Melcangi RC. Post-finasteride syndrome and post-SSRI sexual dysfunction: two sides of the same coin? Endocrine.

Coskuner ER, Culha MG, Ozkan B, Kaleagasi EO. Post-SSRI Sexual Dysfunction: Preclinical to Clinical. Is It Fact or Fiction? Sexual Medicine Reviews.

2017

Muquebil Ali Al Shaban Rodríguez OW, Álvarez de Morales Gómez-Moreno E, Fernández Fernández J, Fresno García C, del Mar Fernández Fernández M. Disfunción sexual persistente tras el tratamiento con inhibidores selectivos de la recaptación de serotonina: a propósito de un caso tras la retirada de paroxetina. Psiquiatría Biológica.

Bala A, Tue Nguyen HM, Hellstrom WJG. *Post-SSRI Sexual Dysfunction: A Literature Review. Sexual Medicine Reviews.

Reisman Y. Sexual Consequences of Post-SSRI Syndrome. Sexual Medicine Reviews.

2016

Simonsen AL, Danborg PB, Gøtzsche PC. Persistent sexual dysfunction after early exposure to SSRIs: Systematic review of animal studies. International Journal of Risk & Safety in Medicine.

2015

Vašečková B. Sexual dysfunction persisting after treatment with antidepressants (In Slovak). Psychiatria pre prax.

Ben-Sheetrit J, Aizenberg D, Csoka AB, Weizman A, Hermesh H. Post-SSRI Sexual Dysfunction: Clinical Characterization and Preliminary Assessment of Contributory Factors and Dose-Response Relationship. Journal of Clinical Psychopharmacology.

2014

Waldinger MD, van Coevorden RS, Schweitzer DH, Georgiadis J. Penile anesthesia in Post SSRI Sexual Dysfunction (PSSD) responds to low-power laser irradiation: a case study and hypothesis about the role of transient receptor potential (TRP) ion channels. European Journal of Pharmacology.

Hogan C, Le Noury J, Healy D, Mangin D. *One hundred and twenty cases of enduring sexual dysfunction following treatment. International Journal of Risk & Safety in Medicine.

Ekhart GC, van Puijenbroek EP. *Does sexual dysfunction persist upon discontinuation of selective serotonin reuptake inhibitors? (In Dutch). Tijdschrift voor Psychiatrie.

2013

Stinson RD. *The impact of persistent sexual side effects of selective serotonin reuptake inhibitors after discontinuing treatment: a qualitative study. PhD (Doctor of Philosophy) thesis, University of Iowa.

2012

*SSRIs and persistent sexual dysfunction. Netherlands Pharmacovigilance Centre Lareb.

2009

Farnsworth KD, Dinsmore WW. Persistent sexual dysfunction in genitourinary medicine clinic attendees induced by selective serotonin reuptake inhibitors. International Journal of STD & AIDS.

2008

Bahrick AS, Harris MM. *Sexual Side Effects of Antidepressant Medications: An Informed Consent Accountability Gap. Journal of Contemporary Psychotherapy.

Kauffman RP. Persistent Sexual Side Effects after Discontinuation of Psychotropic Medications. Primary Psychiatry.

Bahrick AS. *Persistence of Sexual Dysfunction Side Effects after Discontinuation of Antidepressant Medications: Emerging Evidence. The Open Psychology Journal.

Csoka AB, Bahrick A, Mehtonen OP. *Persistent sexual dysfunction after discontinuation of selective serotonin reuptake inhibitors. The Journal of Sexual Medicine.

2007

Kauffman RP, Murdock A. *Prolonged Post-Treatment Genital Anesthesia and Sexual Dysfunction Following Discontinuation of Citalopram and the Atypical Antidepressant Nefazodone. The Open Women’s Health Journal.

2006

Bahrick AS. *Post SSRI sexual dysfunction. American Society for the Advancement of Pharmacotherapy Tablet.

Csoka AB, Shipko S. Persistent sexual side effects after SSRI discontinuation. Psychotherapy and Psychosomatics.

Bolton JM, Sareen J, Reiss JP. Genital anaesthesia persisting six years after sertraline discontinuation. Journal of Sex & Marital Therapy.

Note: A list of academic literature about post-finasteride syndrome (PFS), which is generally regarded as a related condition to PSSD, can be found on the PFS Foundation website.

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