Drug Search by Year (Detail)

26897888

US

Skin cancer, Squamous cell carcinoma, Precancerous condition, Thrombosis, Pulmonary embolism, Oesophageal stenosis, Barrett^s oesophagus, Mental impairment, Haemorrhage, Dry mouth, Skin infection, Pain, Diarrhoea, Dry throat, Dyspnoea exertional, Vomiting, Mobility decreased, Confusional state, Dyspnoea, Feeling abnormal, Arthropathy, Fatigue, Nausea, Arthralgia, Blood glucose abnormal, Breakthrough pain, Abdominal distension, Peripheral swelling, Tooth fracture, Pruritus, Hyperreflexia, Paraesthesia, Epistaxis, Skin ulcer, Musculoskeletal stiffness, Eating disorder, Early satiety, Pain of skin, Tooth disorder, Sensitive skin, Oral candidiasis, Dry eye, Oliguria, Mental status changes, Restless legs syndrome, Muscle twitching, Ocular hyperaemia, Weight increased, Contusion, Dizziness, Blood pressure increased, Headache, Feeling hot, Anxiety, Dysphagia, Full blood count abnormal, Myalgia, Abdominal discomfort, Depression, Polyp, Rib fracture, Memory impairment, Fall, Bone pain, Cystic lung disease, Aggression, Platelet count increased, Malaise, Insomnia, Irritability, Oral discomfort, Pulmonary mass, Hyperhidrosis, Vitamin D decreased, Skin exfoliation, Gastrooesophageal reflux disease, Balance disorder, Pigmentation disorder, Skin burning sensation, Tremor, Nervousness, Weight decreased, Dry skin, Impaired healing, Product dose omission issue,

RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, AMOXICILLIN, HYDROXYUREA, CLOPIDOGREL, CLOPIDOGREL BISULFATE, CLOPIDOGREL, CLOPIDOGREL BISULFATE, MORPHINE SULFATE, RIVAROXABAN, METHOCARBAMOL, METHOCARBAMOL TABLETS, ALPRAZOLAM, SUCRALFATE, HYDROCHLOROTHIAZIDE, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, PAROXETINE, PAROXETINE HYDROCHLORIDE, PAROXETINE HYDROCHLORIDE HEMIHYDRATE, FOLIC ACID, MIRTAZAPINE, CLONAZEPAM, ERGOCALCIFEROL, BUPROPION, ERGOCALCIFEROL, GABAPENTIN, OXYCODONE HYDROCHLORIDE, TETRAHYDROZOLINE HYDROCHLORIDE, CYCLOSPORINE,

26898779

IN

Monocyte count decreased, Blood pressure increased, Headache, Off label use,

RIBOCICLIB, RIBOCICLIB,

26898801

US

Muscle atrophy, Fear of death, Musculoskeletal chest pain, Feeling hot, Arthralgia, Hyperhidrosis, Blood pressure increased, Heart rate increased, Nausea, Myalgia, Inappropriate schedule of product administration,

26899091

CA

Pneumonia, Nasal congestion, Infection, Sinusitis, Sleep disorder due to a general medical condition, Vertigo, Urticaria, Vomiting, Rhinitis, Therapeutic product effect decreased, Nasopharyngitis, Decreased activity, Oropharyngeal pain, Stress, Dyspnoea exertional, Eczema, Feeding disorder, Psoriasis, Dizziness, Full blood count abnormal, Pain, Cough, Diarrhoea, Influenza, Tooth abscess, Ear infection, Drug ineffective, Product administration error, Asthma, Middle insomnia, Abdominal pain, Loss of personal independence in daily activities, Upper-airway cough syndrome, Wheezing, Productive cough, Migraine, Therapeutic response decreased, Blood pressure increased, Eosinophil count abnormal, Bacterial infection, Terminal insomnia, Dyspnoea, Anxiety, Fungal infection, Urinary tract infection, Musculoskeletal chest pain, Restrictive pulmonary disease, Nasal discharge discolouration, Emphysema, Forced expiratory volume decreased, Rales, Malaise, Tachycardia, Heart rate increased, Sleep disorder, Obstructive airways disorder,

FLUTICASONE PROPIONATE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, IPRATROPIUM BROMIDE, SULFAMETHOXAZOLE AND TRIMETHOPRIM, MEPOLIZUMAB, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, OMALIZUMAB,

26899184

JP

Hypertensive emergency, Blood pressure increased,

VOCLOSPORIN, HYDROXYCHLOROQUINE SULFATE, HYDROXYCHLOROQUINE SULFATE, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, LOSARTAN POTASSIUM, LOSARTAN,

26899649

Tardive dyskinesia, Anticholinergic effect, Intention tremor, Postural tremor, Resting tremor, Blood pressure increased,

QUETIAPINE, QUETIAPINE, QUETIAPINE, DESVENLAFAXINE, DESVENLAFAXINE SUCCINATE, DESVENLAFAXINE, DESVENLAFAXINE SUCCINATE, DESVENLAFAXINE, DESVENLAFAXINE SUCCINATE, DESVENLAFAXINE, DESVENLAFAXINE SUCCINATE, ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, LITHIUM, LITHIUM BROMATUM, LITHIUM, LITHIUM BROMATUM, LITHIUM, LITHIUM BROMATUM, LITHIUM, LITHIUM BROMATUM, LITHIUM, LITHIUM BROMATUM, LITHIUM, LITHIUM BROMATUM, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), OXCARBAZEPINE, OXCARBAZEPINE, OXCARBAZEPINE, PROPRANOLOL HYDROCHLORIDE, PROPRANOLOL HYDROCHLORIDE, CARIPRAZINE, CARIPRAZINE, MODAFINIL, MIRTAZAPINE, MIRTAZAPINE,

26899721

EU

Blindness transient, Blood pressure increased, Drug interaction, Dyschromatopsia, Constipation, Photosensitivity reaction, Urticaria, Adverse reaction,

DULOXETINE HYDROCHLORIDE, DULOXETINE, CLOMIPRAMINE HYDROCHLORIDE, ALPRAZOLAM, OLANZAPINE, LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, QUETIAPINE,

26900005

CA

Anxiety, Arterial occlusive disease, Balance disorder, Blood test abnormal, Body temperature decreased, Breath sounds abnormal, Chronic obstructive pulmonary disease, Contusion, Dizziness postural, Dyspnoea exertional, Gait disturbance, Hyperhidrosis, Insomnia, Lacrimal disorder, Limb discomfort, Lung neoplasm malignant, Musculoskeletal discomfort, Night sweats, Rales, Road traffic accident, Stress, Wheezing, Blood pressure systolic increased, Blood pressure increased, Pain, Discomfort, Hernia, Hernia pain, Hypersomnia, Lower respiratory tract infection, Weight decreased, Dizziness, Asthenia, Injection site swelling, Injection site pain, Injection site mass, Respiratory rate increased, Arthralgia, Cough, Depression, Malaise, Pneumonia, Fatigue, Dyspnoea, Diarrhoea, Abdominal pain, Product storage error, Needle issue,

METHOTREXATE, METHOTREXATE SODIUM, LEFLUNOMIDE, AMLODIPINE BESYLATE, OCTREOTIDE ACETATE, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, FOLIC ACID, RISEDRONATE SODIUM, ALBUTEROL SULFATE, ALBUTEROL, TIOTROPIUM BROMIDE,

26900189

GB

Colitis microscopic, Hypothyroidism, Hypertransaminasaemia, Feeling cold, Fatigue, Blood pressure increased, Cortisol decreased,

LENVATINIB, LENVATINIB, PEMBROLIZUMAB, LANSOPRAZOLE, METOCLOPRAMIDE, METOCLOPRAMIDE HYDROCHLORIDE,

26900332

US

Blood pressure increased, Spinal fracture, Road traffic accident, Injury, Clavicle fracture, Cerebral haemorrhage, Diaphragmatic injury, Rib fracture, Dyspepsia, Decreased appetite, Physical deconditioning, Exostosis, Hyperkeratosis, Thyroid disorder, Blood calcium increased, Headache, Dysphonia, Balance disorder, Feeling drunk, Brain fog, Bradykinesia, Arthralgia, Nausea, Blood creatinine increased, Blood calcium decreased, Blood pressure fluctuation, Oropharyngeal pain, Productive cough, Abdominal pain lower, Diarrhoea, Clostridium difficile infection, Asthenia, Hypersensitivity, Arthropathy, Vomiting, Arrhythmia, Respiratory tract infection, Dehydration, Renal impairment, Proteinuria, Blood urea increased, Fatigue, Limb injury, Peripheral swelling, Carbohydrate antigen 125 increased, Malignant neoplasm progression, Tracheal inflammation, Dysphagia, Oropharyngeal swelling, Radiation associated pain, Myalgia, Oesophageal wall hypertrophy,

LENVATINIB, LENVATINIB, LENVATINIB, LENVATINIB, LENVATINIB, LENVATINIB, LENVATINIB, CALCIUM, CALCIUM, CALCIUM,

26901058

Cardiac failure, Blood pressure increased, Hepatic function abnormal, Hypertensive heart disease, Brain natriuretic peptide increased,

FINERENONE, FINERENONE,

26901894

US

Dyspnoea, Injection site erythema, Injection site pruritus, Injection site rash, Blood pressure increased,

INCLISIRAN, INCLISIRAN, INCLISIRAN, EPINEPHRINE, DIPHENHYDRAMINE HYDROCHLORIDE,

26901963

EG

Nosocomial infection, Inappropriate schedule of product administration, Inappropriate schedule of product administration, Blood pressure increased, Epistaxis, Gait disturbance,

PEMBROLIZUMAB,

26901997

EU

Vitreous haemorrhage, Blood pressure increased,

ERENUMAB-AOOE,

26902249

CA

Abdominal pain, Blood pressure increased,

26892711

EU

Vasculitis, Arthralgia, Blood pressure increased, Rash, Food interaction,

METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, LEVOTHYROXINE SODIUM,

26892960

US

Blood pressure increased, Product design issue,

ALBUTEROL SULFATE,

26892974

US

Blood pressure increased, Heart rate increased,

LEVOCETIRIZINE DIHYDROCHLORIDE,

26893176

JP

Clavicle fracture, Fall, Blood pressure increased, Overdose,

SACUBITRIL AND VALSARTAN, SACUBITRIL AND VALSARTAN, AMLODIPINE,

26893431

IN

Breast cancer, Malignant neoplasm progression, Metastases to uterus, Neutropenia, Hepatobiliary infection, Eastern Cooperative Oncology Group performance status abnormal, Pleural effusion, Breast mass, Blood pressure increased,

RIBOCICLIB, RIBOCICLIB, RIBOCICLIB,

26893566

US

Blood pressure increased,

NAPROXEN SODIUM, DEXTROMETHORPHAN HYDROBROMIDE, GUAIFENESIN, GUAIFENESIN, NAPROXEN SODIUM, PSEUDOEPHEDRINE HYDROCHLORIDE,

26893578

CN

Drug eruption, Pruritus, Erythema, Skin temperature increased, Pain, Skin lesion, Blood pressure increased,

INCLISIRAN,

26893584

US

Fatigue, Muscular weakness, Back pain, Oedema, Arthralgia, Pain in extremity, Cataract, End stage renal disease, Autoimmune disorder, Injection site discomfort, Skin striae, Injection site bruising, Nasopharyngitis, Vision blurred, Myalgia, Energy increased, Insomnia, Epistaxis, Blood pressure increased, Intraocular pressure test abnormal,

PREDNISONE, AMLODIPINE BESYLATE, SULFAMETHOXAZOLE AND TRIMETHOPRIM, CARVEDILOL, FAMOTIDINE, HYDRALAZINE HYDROCHLORIDE, HYDRALAZINE HYDROCHLORIDE, ROSUVASTATIN CALCIUM, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, TORSEMIDE,

26894429

CA

Adjustment disorder, Affect lability, Angina pectoris, Anxiety, Aphasia, Arterial occlusive disease, Arthritis, Asthenia, Blood pressure increased, Carotid artery thrombosis, Cataract, Cerebrovascular accident, Chest discomfort, Confusional state, Coordination abnormal, Cough, Cystitis, Dysarthria, Dysphagia, Eating disorder, Fall, Fatigue, Gangrene, Gastrointestinal disorder, Headache, Hemiparesis, Hemiplegia, Influenza, Influenza like illness, Malaise, Motor dysfunction, Muscle spasticity, Muscular weakness, Nasopharyngitis, Nausea, Neurologic neglect syndrome, Pain, Palpitations, Personality disorder, Pneumonia, Product use issue, Psoriasis, Pyrexia, Respiratory tract congestion, Rheumatoid arthritis, Rhinorrhoea, Sensory loss, Sinus congestion, Sinus disorder, Sinusitis, Skin exfoliation, Skin haemorrhage, Sneezing, Vomiting,

LISINOPRIL, ESOMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM, RAMIPRIL,

26894432

BR

Blood cholesterol increased, Blood pressure increased, Nodule, Vaginal haemorrhage, Neoplasm recurrence, Bone neoplasm, Tumour inflammation, Neutropenia, Febrile neutropenia, Breast cancer metastatic, Malignant neoplasm progression, Hyperhidrosis, Madarosis, Pain, Pain, Pain, Menstrual disorder, Hair growth abnormal, Insomnia, Decreased immune responsiveness, Fatigue, Asthenia, Alopecia, Swelling, Weight increased, Hormone level abnormal, Feeling abnormal, Polymerase chain reaction positive, Iron deficiency, Sensory loss, Menstrual disorder, Menstrual disorder, Breast swelling, Nervousness, Crying, Weight decreased, Feeling hot, Skin burning sensation, Erythema, Erythema, Breast swelling, Gene mutation, Breast pain, Cardiac disorder, Blood triglycerides increased, Anaemia, Breast swelling, Application site injury, Application site oedema, Application site discolouration, Infection, Anal incontinence, Malaise, Feeling cold, Diarrhoea, Platelet count decreased, Abdominal pain upper, Abdominal pain, Abdominal pain, Pyrexia, Therapy non-responder, Headache, Headache, Vision blurred, Vision blurred, Vision blurred, Abdominal pain, Faeces soft, Blood glucose increased, Tinnitus, Mood altered, Ear pain, Dry mouth, Skin exfoliation, Pruritus, Irritability,

CIPROFLOXACIN HYDROCHLORIDE, LETROZOLE, LETROZOLE TABLETS, LETROZOLE, LETROZOLE TABLETS, RIBOCICLIB, RIBOCICLIB, RIBOCICLIB, RIBOCICLIB, GOSERELIN, DENOSUMAB, ALPELISIB, FULVESTRANT, SACCHAROMYCES CEREVISIAE, METRONIDAZOLE,

26894743

CA

Rheumatoid arthritis, Blood pressure increased,

TOFACITINIB, TOFACITINIB CITRATE, METHOTREXATE, METHOTREXATE SODIUM, RITUXIMAB, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, DIPHENHYDRAMINE, DIPHENHYDRAMINE HYDROCHLORIDE, PREDNISONE, METHYLPREDNISOLONE,

26895101

VN

Cerebral haemorrhage, Hemiplegia, Blood pressure increased, Altered state of consciousness, Vomiting,

RIVAROXABAN,

26895328

US

Exophthalmos, Heavy menstrual bleeding, Menstruation irregular, Peripheral swelling, Poor venous access, Incorrect dose administered, Blood pressure increased, Blood thyroid stimulating hormone increased,

TEPROTUMUMAB, TEPROTUMUMAB, TEPROTUMUMAB,

26895477

Injection related reaction, Pain, Bone pain, Arthralgia, Myalgia, Headache, Blood pressure increased,

ABALOPARATIDE, IVABRADINE, ALIROCUMAB, DULAGLUTIDE, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, PREGABALIN, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, LANSOPRAZOLE, ICOSAPENT ETHYL, CETIRIZINE HYDROCHLORIDE, MOMETASONE FUROATE, ERGOCALCIFEROL,

26895669

US

Blood pressure increased, Dysphonia, Nausea, Headache, Dizziness,

ABALOPARATIDE, CALCIUM, ACETAMINOPHEN,

26895674

EU

Body temperature increased, Syncope, Hypovolaemia, Gastrointestinal toxicity, Colitis, Hepatic enzyme increased, Fall, Fatigue, Blood pressure increased, General physical health deterioration, Feeding disorder, Illness, Feeling hot, Gastrointestinal disorder, Diarrhoea, Vomiting,

RIBOCICLIB, RIBOCICLIB,

26895890

Blood pressure increased, Oxygen saturation decreased, Chills, Pyrexia,

CETUXIMAB,

26895948

CN

Tremor, Blood pressure increased,

OBINUTUZUMAB,

26896594

US

Intervertebral disc disorder, Granuloma, Limb discomfort, Pain in extremity, Mobility decreased, Secretion discharge, Soft tissue injury, Feeling abnormal, Visual impairment, Swelling face, Face oedema, Eye swelling, Panic attack, Candida infection, Vision blurred, Monoclonal immunoglobulin increased, Vomiting, Defaecation disorder, Gastrooesophageal reflux disease, Nausea, Diarrhoea, Abdominal distension, Fatigue, Streptococcal infection, Tooth disorder, Tooth abscess, Tooth fracture, Blood pressure increased, Blood cholesterol abnormal, Attention deficit hyperactivity disorder, Iron deficiency, Metabolic disorder, Vitamin B12 abnormal, Product dose omission issue,

CABOTEGRAVIR AND RILPIVIRINE, CABOTEGRAVIR AND RILPIVIRINE, CABOTEGRAVIR AND RILPIVIRINE, DOLUTEGRAVIR SODIUM AND LAMIVUDINE, BICTEGRAVIR SODIUM, EMTRICITABINE, AND TENOFOVIR ALAFENAMIDE FUMARATE, EMTRICITABINE AND TENOFOVIR DISOPROXIL FUMARATE, ATAZANAVIR, MAGNESIUM,

26896833

CH

Syncope, Blood pressure increased, Muscle rigidity, Involuntary vocalisation, Urinary incontinence, Nausea, Vomiting, Emotional distress, Crying, Fear,

FREMANEZUMAB-VFRM,

26897153

US

Dyspnoea, Blood pressure increased, Dizziness,

FLUTEMETAMOL F-18, MEMANTINE, MEMANTINE HYDROCHLORIDE, GALANTAMINE HYDROBROMIDE, DRONEDARONE,

26897318

US

Blood glucose increased, Blood pressure increased, Nicotine dependence, Illness, Feeding disorder, Sleep disorder, Decreased appetite, Drug ineffective,

TIRZEPATIDE,

26897508

US

Fall, Blood pressure increased, Acute kidney injury,

RISANKIZUMAB-RZAA,

26886710

Pulmonary oedema, Blood pressure increased, Product administration error,

PHENYLEPHRINE, ETOMIDATE, ETOMIDATE INJECTION, FENTANYL, ROCURONIUM BROMIDE, PROPOFOL, SEVOFLURANE,

26886899

CN

Chest discomfort, Dyspnoea, Dysphoria, Orthopnoea, Cyanosis, Tachypnoea, Tachycardia, Oxygen saturation decreased, Blood pressure increased, Wheezing,

OBINUTUZUMAB, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE, CALCIUM GLUCONATE, CIMETIDINE,

26887218

US

Sneezing, Loss of personal independence in daily activities, Feeling abnormal, Nightmare, Heart rate decreased, Asthma, Drug intolerance, Fatigue, Dysarthria, Vomiting, Blood pressure increased, Oxygen saturation decreased, Anxiety, Heart rate increased, Flushing, Hypotension, Dizziness, Headache, Dyspnoea, Nausea, Cough, Blood pressure decreased,

TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, NINTEDANIB, OXYGEN, 0XYGEN, ALBUTEROL SULFATE, ALBUTEROL, DICLOFENAC SODIUM, CYCLOBENZAPRINE, GABAPENTIN, PIRFENIDONE, CETIRIZINE HYDROCHLORIDE, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, CALCIUM, LIDOCAINE PATCH 5%, HYDROXYZINE, FLUTICASONE FUROATE AND VILANTEROL TRIFENATATE, ERGOCALCIFEROL, IRON, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, FAMOTIDINE, HYDROCHLOROTHIAZIDE, IBUPROFEN SODIUM, IBUPROFEN, IBUPROFEN TABLETS, COATED,

26887230

US

Blood pressure increased,

ESKETAMINE HYDROCHLORIDE, ESKETAMINE HYDROCHLORIDE,

26887686

CA

Abdominal pain, Anxiety, Asthma, Bacterial infection, Blood pressure increased, Cough, Decreased activity, Diarrhoea, Dizziness, Dyspnoea, Dyspnoea exertional, Ear infection, Eczema, Emphysema, Eosinophil count abnormal, Feeding disorder, Forced expiratory volume decreased, Full blood count abnormal, Fungal infection, Heart rate increased, Infection, Influenza, Loss of personal independence in daily activities, Malaise, Migraine, Middle insomnia, Musculoskeletal chest pain, Nasal congestion, Nasal discharge discolouration, Nasopharyngitis, Pneumonia, Obstructive airways disorder, Oropharyngeal pain, Pain, Productive cough, Psoriasis, Rales, Restrictive pulmonary disease, Rhinitis, Sinusitis, Sleep disorder, Sleep disorder due to a general medical condition, Stress, Tachycardia, Terminal insomnia, Tooth abscess, Upper-airway cough syndrome, Urinary tract infection, Urticaria, Vertigo, Vomiting, Wheezing, Drug ineffective, Therapeutic product effect decreased, Therapeutic response decreased, Product administration error,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, IPRATROPIUM BROMIDE, SULFAMETHOXAZOLE AND TRIMETHOPRIM, FLUTICASONE PROPIONATE, FLUTICASONE PROPIONATE NASAL, MEPOLIZUMAB, OMALIZUMAB,

26887998

CN

Blood pressure fluctuation, Blood pressure increased, Chest discomfort, Palpitations, Dizziness, Rash erythematous, Pruritus,

IODIXANOL,

26888414

US

Anxiety, Heart rate increased, Drug interaction, Illness, Blood pressure increased, Vomiting, Myalgia,

VOCLOSPORIN,

26888543

EU

Tachycardia, Blood pressure increased, Headache, Dizziness,

METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, ANAGRELIDE HYDROCHLORIDE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, FENOFIBRATE, LEVOTHYROXINE SODIUM, TELMISARTAN,

26889008

CA

Small intestine carcinoma, Vomiting, Cough, Wrong technique in product usage process, Nausea, Needle issue, Injection site pain, Hepatic enzyme increased, Weight increased, Headache, Abdominal pain, White blood cell count increased, Malaise, Blood glucose increased, Abdominal pain upper, Pruritus, Diarrhoea, Blood pressure increased, Nasal congestion, Injection site haemorrhage, Fatigue, Malignant neoplasm progression, Underdose, Body temperature decreased,

ROSUVASTATIN CALCIUM, OCTREOTIDE ACETATE, OCTREOTIDE ACETATE, EMPAGLIFLOZIN,

26889123

Dizziness, Asthenia, Atrial fibrillation, Blood pressure increased, SARS-CoV-2 test positive, Therapy interrupted,

CARBOPLATIN,

26889250

CA

Cardiac operation, Blood pressure increased, Muscle spasms, Pollakiuria, Gastroenteritis viral, Vertigo, Product dose omission in error,

TOLVAPTAN, TOLVAPTAN,

26889724

CN

Chest discomfort, Sinus bradycardia, Blood pressure increased, Oxygen saturation decreased, Arrhythmia,

RITUXIMAB,

26890251

EU

Immune-mediated thyroiditis, Stomatitis, Pain, Dyspnoea, Hypoacusis, Blood pressure increased, Gastrointestinal disorder, Clostridium colitis, Chronic obstructive pulmonary disease, Candida infection, Constipation,

IPILIMUMAB, IPILIMUMAB, NIVOLUMAB, NIVOLUMAB, NIVOLUMAB, CARBOPLATIN, CARBOPLATIN, CARBOPLATIN, PEMETREXED, PEMETREXED DISODIUM, PEMETREXED, PEMETREXED DISODIUM, PEMETREXED, PEMETREXED DISODIUM, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, OXAZEPAM, PANTOPRAZOLE, FLUTICASONE PROPIONATE,

26890280

US

Erythema, Blood pressure increased,

PACLITAXEL, PACLITAXEL (AIBUMIN-BOUND),

26890513

EU

Cough, Dyspnoea, Oxygen saturation decreased, Chills, Pyrexia, Blood pressure increased, Heart rate increased,

NIVOLUMAB, NIVOLUMAB, OXALIPLATIN, OXALIPLATIN, LEUCOVORIN CALCIUM, GRANISETRON, GRANISETRON HYDROCHLORIDE, FAMOTIDINE, FLUOROURACIL CREAM, 0.5%, FLUOROURACIL,

26890584

US

Erythema, Blood pressure increased,

PACLITAXEL, PACLITAXEL (AIBUMIN-BOUND),

26890585

US

Erythema, Blood pressure increased,

PACLITAXEL, PACLITAXEL (AIBUMIN-BOUND),

26890986

CN

Tachypnoea, Temperature intolerance, Chills, Blood pressure increased, Respiratory rate increased, Body temperature decreased,

OBINUTUZUMAB, SODIUM CHLORIDE, SODIUM CHLORIDE TABLET, SODIUM CHLORIDE TABLETS,

26891113

US

Electric shock sensation, Hypoaesthesia, Blood pressure increased, Product use in unapproved indication, Underdose,

BREXPIPRAZOLE, BREXPIPRAZOLE, BREXPIPRAZOLE, SERTRALINE, SERTRALINE, PRAZOSIN, PRAZOSIN, BENZTROPINE, BENZTROPINE,

26891259

CN

Bile duct stone, Nephrolithiasis, Hepatic calcification, Mesenteric panniculitis, Transaminases increased, Electrocardiogram abnormal, Blood pressure increased, Hepatic hamartoma, Hepatic function abnormal, Cholecystitis,

TIRZEPATIDE,

26891716

EU

Death, Immune-mediated thyroiditis, Clostridium colitis, Hypoacusis, Blood pressure increased, Gastrointestinal disorder, Chronic obstructive pulmonary disease, Dyspnoea, Pain, Stomatitis, Candida infection, Constipation,

PEMETREXED, PEMETREXED DISODIUM, PEMETREXED, PEMETREXED DISODIUM, PEMETREXED, PEMETREXED DISODIUM, CARBOPLATIN, CARBOPLATIN, CARBOPLATIN, NIVOLUMAB, NIVOLUMAB, NIVOLUMAB, IPILIMUMAB, IPILIMUMAB, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, OXAZEPAM, PANTOPRAZOLE, FLUTICASONE PROPIONATE,

26891722

US

Pain, Feeling abnormal, Blood pressure increased, Sedation, Dissociation, Oxygen saturation abnormal,

ESKETAMINE HYDROCHLORIDE, ESKETAMINE HYDROCHLORIDE, ESKETAMINE HYDROCHLORIDE,

26894307

Blood pressure increased,

ESKETAMINE HYDROCHLORIDE,

26894571

Blood pressure increased, Supraventricular tachycardia,

LETROZOLE, LETROZOLE TABLETS, ACETAMINOPHEN, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE, ACETAMINOPHEN, ALBUTEROL SULFATE, ALBUTEROL,

26895596

Heart rate increased, Blood pressure increased, Chest discomfort, Gait disturbance, Dizziness, Disorientation, Vision blurred,

MELOXICAM, IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN TABLET, FILM COATED, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE,

26881406

CN

Tachypnoea, Hyperhidrosis, Dyspraxia, Blood pressure increased, Throat tightness,

INSULIN ASPART,

26881535

EU

Arteriospasm coronary, Blood pressure increased, Injection site reaction,

ASFOTASE ALFA, LORATADINE, LORATADINE ORAL,

26881619

Blood pressure increased, Post procedural complication, Pyrexia, Maternal exposure during delivery,

BUPIVACAINE, BUPIVACAINE HYDROCHLORIDE IN DEXTROSE, LIDOCAINE HYDROCHLORIDE, LIDOCAINE HYDROCHLORIDE ANHYDROUS, OXYTOCIN,

26881620

Blood pressure increased, Post procedural complication, Pyrexia, Maternal exposure during delivery,

BUPIVACAINE, BUPIVACAINE HYDROCHLORIDE IN DEXTROSE, LIDOCAINE HYDROCHLORIDE, LIDOCAINE HYDROCHLORIDE ANHYDROUS, OXYTOCIN,

26881621

Blood pressure increased, Post procedural complication, Pyrexia, Maternal exposure during delivery,

BUPIVACAINE, BUPIVACAINE HYDROCHLORIDE IN DEXTROSE, LIDOCAINE HYDROCHLORIDE, LIDOCAINE HYDROCHLORIDE ANHYDROUS, OXYTOCIN,

26881622

Blood pressure increased, Post procedural complication, Pyrexia, Maternal exposure during delivery,

BUPIVACAINE, BUPIVACAINE HYDROCHLORIDE IN DEXTROSE, LIDOCAINE HYDROCHLORIDE, LIDOCAINE HYDROCHLORIDE ANHYDROUS, OXYTOCIN,

26882266

US

Nausea, Neck pain, Throat irritation, Tension headache, Anxiety, Dyspepsia, Skin burning sensation, Flushing, Pain, Chest pain, Dyspnoea, Blood pressure increased, Headache, Dyspnoea exertional, Therapy non-responder,

TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, ATORVASTATIN CALCIUM, ATORVASTATIN CALCIUM, FILM COATED, OXYCODONE HYDROCHLORIDE AND ACETAMINOPHEN, EMPAGLIFLOZIN, SILDENAFIL CITRATE, SILDENAFIL, GABAPENTIN, SOTATERCEPT-CSRK, LEVOTHYROXINE SODIUM, LEVOTHYROXINE SODIUM ANHYDROUS, METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, OXYGEN, 0XYGEN, BUMETANIDE, SPIRONOLACTONE, BUPROPION HYDROCHLORIDE, DOCUSATE SODIUM 50 MG AND SENNOSIDES 8.6 MG, DOCUSATE SODIUM AND SENNOSIDES, DULOXETINE HYDROCHLORIDE, DULOXETINE, NAPROXEN, NAPROXEN SODIUM, ONDANSETRON HYDROCHLORIDE, ALBUTEROL SULFATE,

26883117

US

Psoriatic arthropathy, Drug ineffective, Blood pressure increased, Fatigue, Dry eye, Dry mouth, Overweight, Therapy interrupted,

ETANERCEPT, APREMILAST, ALBUTEROL SULFATE, ALBUTEROL, ERGOCALCIFEROL, HYDROXYZINE HYDROCHLORIDE, HYDROXYZINE, HYDROXYZINE HYDROCHLORIDE ORAL, POTASSIUM CITRATE, TRIAMCINOLONE ACETONIDE, TRIAMCINOLONE ACETONIDE OINTMENT USP, 0.05%, CETIRIZINE HYDROCHLORIDE, METHOTREXATE SODIUM,

26883150

US

Pancreatitis acute, Unevaluable event, Blood pressure increased, Oxygen saturation increased,

26883388

CA

Nasopharyngitis, Inappropriate schedule of product administration, Blood pressure increased, Illness, Blood pressure systolic increased,

CERTOLIZUMAB PEGOL, CERTOLIZUMAB PEGOL, FOLIC ACID, ASCORBIC ACID, CALCIUM,

26884265

Asthenia, Blood pressure increased, Hypoaesthesia,

ECULIZUMAB,

26884393

EU

Blood pressure increased,

OMEPRAZOLE, OMEPRAZOLE MAGNESIUM,

26884902

US

Blood pressure increased, Intentional product misuse,

ANAKINRA,

26885009

Blood pressure increased,

ALPELISIB,

26885199

US

Blood pressure increased,

NIRMATRELVIR AND RITONAVIR,

26885637

US

Abortion spontaneous, Blood pressure increased, Nausea, Nasopharyngitis, Vomiting, Exposure during pregnancy,

RAVULIZUMAB, ECULIZUMAB, ECULIZUMAB,

26885663

US

Pneumonia, Pneumonia, Influenza, Blood pressure increased, Gastroenteritis viral, Headache, Chest discomfort, Product dose omission issue,

TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, FUROSEMIDE, LEVOTHYROXINE SODIUM, LEVOTHYROXINE SODIUM ANHYDROUS, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, HYDROXYZINE HYDROCHLORIDE, HYDROXYZINE, HYDROXYZINE HYDROCHLORIDE ORAL, POTASSIUM CHLORIDE, POTASSIUM CHLORIDE EXTENDED-RELEASE, POTASSIUM CHLORIDE, DEXTROSE MONOHYDRATE, POTASSIUM CHLORIDE ORAL, MACITENTAN, ERGOCALCIFEROL, TREPROSTINIL, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM,

26885677

CN

Chills, Palpitations, Blood pressure increased, Heart rate increased, Respiratory rate increased, Pyrexia, Hyperhidrosis, Fibrin D dimer increased, Anaemia, Blood magnesium decreased, Hypoproteinaemia,

IRON SUCROSE, IRON SUCROSE, ALPROSTADIL, ALPROSTADIL, SODIUM CHLORIDE, SODIUM CHLORIDE TABLET, SODIUM CHLORIDE TABLETS, SODIUM CHLORIDE, SODIUM CHLORIDE TABLET, SODIUM CHLORIDE TABLETS, SODIUM CHLORIDE, SODIUM CHLORIDE TABLET, SODIUM CHLORIDE TABLETS,

26885855

US

Cutaneous T-cell lymphoma, Dyspnoea, Blood pressure increased, Dizziness, Cough, Pain, Oxygen saturation decreased, Dyspnoea,

UPADACITINIB, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, HYDROXYZINE,

26885970

US

Dehydration, Abdominal discomfort, Vomiting, Somnolence, Diarrhoea, Blood magnesium decreased, Blood pressure increased,

LENVATINIB, MAGNESIUM CHLORIDE, PEMBROLIZUMAB, IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN TABLET, FILM COATED, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE, SERTRALINE HYDROCHLORIDE, ONDANSETRON HYDROCHLORIDE, FAMOTIDINE,

26886154

US

Blood pressure increased,

VALBENAZINE,

26886229

US

Visual impairment, Eye swelling, Dysphonia, Blood pressure increased, Flushing, Headache,

FLUTEMETAMOL F-18, EZETIMIBE, ROSUVASTATIN, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, DICLOFENAC SODIUM, DICLOFENAC SODIUM TOPICAL, DICLOFENAC SODIUM TOPICAL GEL, 1%, DICLOFENAC, DICLOFENAC SODIUM 1%,

26886234

US

Thrombosis, Blood pressure increased,

LIDOCAINE, LIDOCAINE HYDROCHLORIDE, BURN RELIEF, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE, LIDICAINE, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE, LIDOCAINE 4%, LIDOCAINE, MENTHOL, GLIPIZIDE, PREDNISONE, PREDNISONE,

26888861

Nausea, Diarrhoea, Fatigue, Muscle spasms, Rash, Blood pressure increased, Weight decreased, Mucosal disorder,

CABOZANTINIB,

26876019

US

Sepsis, Pain, Blood pressure increased,

PANCRELIPASE, PANCRELIPASE,

26876375

JP

Arrhythmia, Blood pressure increased, Anxiety,

DENOSUMAB,

26876513

JP

Blood pressure increased, Cardiac ventricular thrombosis, Coronary artery stenosis, Mitral valve incompetence, Pulmonary valve incompetence,

SACUBITRIL AND VALSARTAN, SACUBITRIL AND VALSARTAN, OXYGEN, 0XYGEN, FUROSEMIDE, FUROSEMIDE, FUROSEMIDE, SPIRONOLACTONE, BISOPROLOL FUMARATE, AMLODIPINE BESYLATE, AMLODIPINE BESYLATE, AMLODIPINE BESYLATE,

26876548

CN

Blood pressure increased,

ESKETAMINE HYDROCHLORIDE,

26876626

AU

Panic attack, Altered state of consciousness, Anxiety, Cardiac disorder, Vision blurred, Heart rate abnormal, Feeling abnormal, Heart rate increased, Blood pressure increased, Discomfort, Sleep disorder due to a general medical condition,

ROMOSOZUMAB-AQQG, ROMOSOZUMAB-AQQG, ACETAMINOPHEN, DEXTROMETHORPHAN HBR, ACETAMINOPHEN AND DIPHENHYDRAMINE HCL, ACETAMINOPHEN, ACETAMINOPHEN AND CAFFEINE, ACETAMINOPHEN AND PHENYLEPRINE HCL, ACETAMINOPHEN, CHLORPHENIRAMINE MALEATE, DEXTROMETHORPHAN HBR, BUDESONIDE AND FORMOTEROL FUMARATE DIHYDRATE, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, ERGOCALCIFEROL, ROSUVASTATIN,

26876692

US

Feeling abnormal, Abdominal discomfort, Food poisoning, Condition aggravated, Weight decreased, Blood pressure increased, Rash papular, Dizziness, Fear of eating, Depression, Anxiety, Panic attack, Food poisoning, Abdominal pain upper, Nausea, Decreased appetite, Rash macular, Erythema, Frustration tolerance decreased, Tearfulness, Condition aggravated, Off label use,

SARILUMAB, SARILUMAB, PEMBROLIZUMAB, ALPRAZOLAM, HYDROXYCHLOROQUINE,

26877644

US

Blood pressure increased, Dizziness,

26877765

US

Blood pressure increased,

DEXLANSOPRAZOLE,

26878075

CN

Hyponatraemia, Hyperplasia adrenal, Nephrocalcinosis, Stenosis, Blood pressure increased, Off label use,

26878106

CO

Chronic myeloid leukaemia, General physical health deterioration, Malignant neoplasm progression, Cholelithiasis, Vaginal haemorrhage, Uterine haemorrhage, Haematochezia, Hypothyroidism, Malaise, Diabetes mellitus, Loose tooth, Toothache, Varicose vein, Drug intolerance, Cardiac disorder, Blood creatinine decreased, Crying, Transferrin saturation decreased, Microalbuminuria, White blood cell count increased, Prothrombin time shortened, Blood lactate dehydrogenase abnormal, Lymphocyte count abnormal, Antinuclear antibody positive, Blood triglycerides increased, Blood cholesterol increased, Product dose omission issue, Iron deficiency anaemia, Varices oesophageal, Blood iron decreased, Alanine aminotransferase abnormal, Aspartate aminotransferase abnormal, Manganese increased, Neutrophil count increased, Mean cell haemoglobin concentration abnormal, Neck pain, Back pain, Pallor, Pain, Peripheral swelling, Oedema peripheral, Normochromic normocytic anaemia, Hepatomegaly, Dyslipidaemia, Hyperglycaemia, Hepatic steatosis, Arthralgia, Ocular hyperaemia, Pain in extremity, Chest pain, Haemoglobin decreased, Anaemia, Dyspnoea, Anxiety, Tachycardia, White blood cell count abnormal, Cough, Blood pressure increased, Cytogenetic analysis abnormal, Hypertension, Depression,

METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, NILOTINIB, NILOTINIB, NILOTINIB, NILOTINIB, NILOTINIB, NILOTINIB, NILOTINIB, NILOTINIB, NILOTINIB, NILOTINIB, NILOTINIB, NILOTINIB, NILOTINIB, NILOTINIB, DICLOFENAC, DICLOFENAC SODIUM, DIPHENHYDRAMINE, DIPHENHYDRAMINE HYDROCHLORIDE, MAGNESIUM SULFATE, MAGNESIUM SULFATE HEPTAHYDRATE, MAGNESIUM SULFATE IN WATER FOR, CALCIUM, FUROSEMIDE,

26878648

IN

Bacterial sepsis, Urosepsis, Rash, Glossitis, Lichen planus, Haemoglobin abnormal, White blood cell count abnormal, Red blood cell sedimentation rate abnormal, Platelet count increased, Mean cell volume abnormal, Red cell distribution width abnormal, Iron deficiency anaemia, Blood pressure increased, Off label use,

RUXOLITINIB, RUXOLITINIB, INSULIN HUMAN,

26878821

US

Blood pressure increased, Cough, Wrong technique in device usage process, Drug dose omission by device, Product packaging quantity issue, Product delivery mechanism issue,

ALBUTEROL SULFATE,

26879277

US

Adverse event, Blood pressure increased, Paraesthesia, Rhinorrhoea, Rosacea, Upper-airway cough syndrome, Paranasal sinus discomfort, Dry mouth, Hunger, Throat irritation, Headache, Flushing,

TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, ATORVASTATIN CALCIUM, ATORVASTATIN CALCIUM, FILM COATED, BIMATOPROST, HYDROCHLOROTHIAZIDE, IVERMECTIN, POTASSIUM CHLORIDE, POTASSIUM CHLORIDE EXTENDED-RELEASE, POTASSIUM CHLORIDE, DEXTROSE MONOHYDRATE, POTASSIUM CHLORIDE ORAL, SODIUM THIOSULFATE, AMLODIPINE BESYLATE, LOSARTAN POTASSIUM, LOSARTAN, ALBUTEROL SULFATE, ERGOCALCIFEROL, LEVOTHYROXINE SODIUM, LEVOTHYROXINE SODIUM ANHYDROUS, LIDOCAINE, LIDOCAINE HYDROCHLORIDE, BURN RELIEF, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE, LIDICAINE, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE, LIDOCAINE 4%, LIDOCAINE, MENTHOL, CYANOCOBALAMIN, HYDROCORTISONE, ANTIPRURITIC (ANTI-ITCH), ANTI-ITCH CREAM, HYDROCORTISONE CREAM, HYDROCORTISONE 1%, HYDROCORTISONE CREAM 1%, HYDROCORTISONE CREAM 1/2%, ANTI-PRURITIC, HYDROCORTISONE CONTINUOUS SPRAY, HYDROCORTISONE LOTION, HYDROCORTISONE ACETATE, ANTI-ITCH, COOL RELIEF GEL WITH ALOE, HYDROCORTISONE SPRAY, DRS. HYDROCORTISONE, ZINC, ZINC GLUCONATE, ZINC CHLORIDE, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, FERROUS SULFATE, DOXEPIN HYDROCHLORIDE, DOXEPN HYDROCHLORIDE, LORAZEPAM, MYCOPHENOLIC ACID, MYCOPHENILIC ACID, TOCILIZUMAB,