Drug Search by Year (Detail)

25036501

FR

Urinary retention, Condition aggravated, Abdominal pain, Hyponatraemia, Drug interaction,

LANSOPRAZOLE, FENTANYL, OXYCODONE HYDROCHLORIDE, OXYCODONE, ESCITALOPRAM OXALATE, ESCITALOPRAM,

25036668

JP

Nausea, Vomiting, Renal disorder, Hyperkalaemia, Immunosuppressant drug level increased, Product use in unapproved indication, Drug interaction,

TACROLIMUS, TACROLIMUS, TACROLIMUS, NIRMATRELVIR AND RITONAVIR, FAMOTIDINE, ATOVAQUONE, MONTELUKAST, NINTEDANIB,

25036766

US

COVID-19, Toxicity to various agents, Off label use, Drug interaction, Drug interaction,

TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, NIRMATRELVIR AND RITONAVIR, PHENYTOIN, LISINOPRIL AND HYDROCHLOROTHIAZIDE, LISINOPRIL AND HYDROCHLOROTHIAZIDE TABLETS,

25036860

GB

Drug interaction,

TIRZEPATIDE, TIRZEPATIDE,

25037097

US

Disorientation, Drug interaction, Confusional state, Somnolence,

PIMAVANSERIN TARTRATE,

25037193

ES

Drug interaction, Rhabdomyolysis, Myopathy toxic, Acute kidney injury, Hypokalaemia, Renal impairment,

ABIRATERONE ACETATE, ABIRATERONE, ABIRATERONE ACETATE, ABIRATERONE, ROSUVASTATIN, PREDNISONE, PREDNISONE,

25037425

IL

Electrocardiogram QT prolonged, Candida infection, Therapeutic product effect decreased, Pyrexia, Drug interaction,

CLOPIDOGREL, CLOPIDOGREL BISULFATE, FLUCONAZOLE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG,

25037504

ES

Vitreous haemorrhage, Arthralgia, Impaired healing, Inflammation, Musculoskeletal discomfort, Drug interaction,

IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE, EDOXABAN TOSYLATE,

25037752

DK

Drug level below therapeutic, Drug interaction,

MEROPENEM, VALPROIC ACID, MELATONIN, CLOBAZAM, LORAZEPAM, HALOPERIDOL, HALOPERIDOL LACTATE, LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE, CLONAZEPAM, MORPHINE, GABAPENTIN, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, PROPOFOL, FENTANYL, PHENOBARBITAL, FOSPHENYTOIN, FOSPHENYTOIN SODIUM, TOPIRAMATE, TOPIRAMATE SPINKLE, LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE,

25037948

FR

Gastrointestinal haemorrhage, Drug interaction,

APIXABAN, PREDNISONE,

25038145

FR

Cognitive disorder, Disorientation, Gamma-glutamyltransferase increased, Aspartate aminotransferase increased, Headache, Mydriasis, Hallucinations, mixed, Sinus tachycardia, Hyperkalaemia, Speech disorder, Drug interaction, Toxicity to various agents, Overdose, Drug abuse, Wrong technique in product usage process,

VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, CITALOPRAM, CITALOPRAM HYDROBROMIDE, ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, PAROXETINE HYDROCHLORIDE HEMIHYDRATE, PAROXETINE, PAROXETINE HYDROCHLORIDE, SERTRALINE, SERTRALINE, ARIPIPRAZOLE ORALLY DISINTEGRATING, ARIPIPRAZOLE, ARIPIPRAZOLE ORAL, ARIPIPRAZOLE ORALLY DISINTEGRATING, ARIPIPRAZOLE, ARIPIPRAZOLE ORAL, RISPERIDONE, HYDROXYZINE, HYDROXYZINE, CETIRIZINE, CETIRIZINE HYDROCHLORIDE, CETIIRIZINE,

25038176

US

Hypertension, Drug interaction, Headache, Nausea, Flushing, Chills, White blood cell count increased,

BUPIVACAINE HYDROCHLORIDE, BUPIVACAINE HYDROCHLORIDE, LIDOCAINE HYDROCHLORIDE, LIDOCAINE HYDROCHLORIDE ANHYDROUS, LIDOCAINE HYDROCHLORIDE, LIDOCAINE HYDROCHLORIDE ANHYDROUS, KENALOG, KENALOG,

25038621

US

Therapeutic response decreased, Apathy, Disturbance in attention, Fatigue, Drug interaction,

DROSPIRENONE, DEXTROAMPHETAMINE SACCHARATE, AMPHETAMINE ASPARTATE, DEXTROAMPHETAMINE SULFATE, AND AMPHETAMINE SULFATE, DEXTROAMPHETAMINE SULFATE, DEXTROAMPHETAMINE SACCHARATE, AMPHETAMINE SULFATE AND AMPHETAMINE ASPARTATE,

25040669

Influenza like illness, Autoimmune disorder, Drug interaction, Blister,

UPADACITINIB,

25029352

US

Drug interaction, Hypotension,

LISINOPRIL, TIZANIDINE, HYDRALAZINE HYDROCHLORIDE, HYDROCHLOROTHIAZIDE, METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, METOPROLOL TARTRATE, METOROPROLOL TARTRATE, METOPROLOL,

25029383

ES

Drug interaction, Renal impairment, Rhabdomyolysis,

ABIRATERONE ACETATE, ABIRATERONE, ROSUVASTATIN, PREDNISONE,

25029384

US

Bradycardia, Drug interaction, Hypotension,

LISINOPRIL, TIZANIDINE, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, CHLORPROMAZINE HYDROCHLORIDE, CHLORPROMAZINE, CHLORPROMAZINE HYDROCHLORIDE, CHLORPROMAZINE, CITALOPRAM, CITALOPRAM HYDROBROMIDE, FINASTERIDE, LIDOCAINE, LIDOCAINE HYDROCHLORIDE, BURN RELIEF, MAXIMUM STRENGTH PAIN RELIEVER, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE, LIDOCAINE 4%, LIDOCAINE, MENTHOL, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, PRAMIPEXOLE DIHYDROCHLORIDE, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, SIMVASTATIN, THEOPHYLLINE, DICLOFENAC, DICLOFENAC SODIUM, DICLOFENAC, DICLOFENAC SODIUM, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, GUAIFENESIN,

25029385

BE

Acute kidney injury, Rhabdomyolysis, Drug interaction,

ABIRATERONE ACETATE, ABIRATERONE, ROSUVASTATIN, PREDNISONE, METOPROLOL TARTRATE, METOPROLOL, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG,

25029393

ES

Acute kidney injury, Drug interaction, Rhabdomyolysis,

ABIRATERONE ACETATE, ABIRATERONE, ROSUVASTATIN, LEVOTHYROXINE, CANDESARTAN, HYDROCHLOROTHIAZIDE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, TRIPTORELIN, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, PREDNISONE, CALCIFEDIOL, CALCIUM CARBONATE, ANTACID, BISOPROLOL FUMARATE, CETIRIZINE, CETIRIZINE HYDROCHLORIDE, CETIIRIZINE, DENOSUMAB,

25029654

CN

Drug interaction, Stevens-Johnson syndrome,

CARBAMAZEPINE, ONABOTULINUMTOXINA,

25029656

PL

Condition aggravated, Pain, Dysphagia, Oropharyngeal pain, Burning sensation, Drug interaction,

ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, DICLOFENAC, DICLOFENAC SODIUM, AMOXICILLIN, SERTRALINE HYDROCHLORIDE, NALTREXONE, BUPROPION HYDROCHLORIDE, BUPROPION, ZOLPIDEM TARTRATE, RAMIPRIL, AMLODIPINE,

25030434

ES

Drug interaction, Rhabdomyolysis, Myopathy,

ROSUVASTATIN, ABIRATERONE ACETATE, ABIRATERONE, PREDNISONE,

25030452

GB

Drug interaction, Nervous system disorder,

EFAVIRENZ, EMTRICITABINE,

25030545

CA

Anxiety, Depression, Depression suicidal, Drug interaction, Loss of personal independence in daily activities, Paranoia, Psychiatric decompensation, Psychomotor skills impaired, Psychotic disorder, Suicidal ideation, Tearfulness, Depressive symptom,

TENOFOVIR DISOPROXIL FUMARATE, LAMIVUDINE, LAMIVUDINE ORAL, ATAZANAVIR, BUPROPION HYDROCHLORIDE, BUPROPION, CLONAZEPAM, ENFUVIRTIDE, RALTEGRAVIR, LOPINAVIR AND RITONAVIR, RISPERIDONE, RITONAVIR, RITONAVIR 100 MG, SERTRALINE, VALPROIC ACID, EMTRICITABINE,

25030566

US

Renal impairment, Drug interaction, Condition aggravated, Hypertension, Toxicity to various agents, Maternal exposure during pregnancy,

DARUNAVIR, DARUNAVIR 600 MG, DARUNAVIR 800 MG, RITONAVIR, RITONAVIR 100 MG, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, AZATHIOPRINE, DOLUTEGRAVIR SODIUM AND RILPIVIRINE HYDROCHLORIDE,

25030617

US

Foetal heart rate deceleration abnormality, Premature delivery, Maternal exposure during pregnancy, Toxicity to various agents, Drug interaction,

TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, AZATHIOPRINE, LAMIVUDINE, LAMIVUDINE ORAL, ABACAVIR SULFATE, ABACAVIR, RITONAVIR, RITONAVIR 100 MG, DARUNAVIR, DARUNAVIR 600 MG, DARUNAVIR 800 MG, BICTEGRAVIR SODIUM, EMTRICITABINE, AND TENOFOVIR ALAFENAMIDE FUMARATE, MAGNESIUM SULFATE, MAGNESIUM SULFATE HEPTAHYDRATE, MAGNESIUM SULFATE IN WATER FOR, MAGNESIUM SULFATE, MAGNESIUM SULFATE HEPTAHYDRATE, MAGNESIUM SULFATE IN WATER FOR, MAGNESIUM SULFATE, MAGNESIUM SULFATE HEPTAHYDRATE, MAGNESIUM SULFATE IN WATER FOR, DOLUTEGRAVIR SODIUM AND RILPIVIRINE HYDROCHLORIDE, RIFAMPIN, NICARDIPINE, LABETALOL, FENTANYL,

25030651

FR

Drug interaction, Encephalopathy,

CLOZAPINE, FLUVOXAMINE MALEATE, VALPROATE SODIUM, AMISULPRIDE,

25030787

AU

Myocarditis, Drug interaction, Treatment failure, Extrapyramidal disorder, Mania,

LURASIDONE HYDROCHLORIDE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, RISPERIDONE, OLANZAPINE, PALIPERIDONE,

25030913

ES

Myoclonus, Wrong dose, Drug interaction,

PREGABALIN, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, RIVASTIGMINE TARTRATE,

25030914

ES

Hip fracture, Drug interaction,

VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, MIRTAZAPINE, MIRTAZAPINE, MIRTAZAPINE, MIRTAZAPINE, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), LORAZEPAM, LORAZEPAM, LORAZEPAM, LORAZEPAM,

25030952

BE

Hepatitis, Drug interaction, Liver function test increased,

AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, AMIKACIN, ALBUTEROL SULFATE, IVACAFTOR,

25031135

GB

Drug interaction,

LOSARTAN, INSULIN GLARGINE-YFGN, INSULIN GLARGINE, AMITRIPTYLINE HYDROCHLORIDE, APIXABAN, BISOPROLOL FUMARATE, CLOPIDOGREL, CLOPIDOGREL BISULFATE, CYANOCOBALAMIN, DAPAGLIFLOZIN, DICLOFENAC SODIUM, DICLOFENAC SODIUM TOPICAL, DICLOFENAC SODIUM TOPICAL GEL, 1%, DICLOFENAC, DICLOFENAC SODIUM 1%, EPLERENONE, FUROSEMIDE, NITROGLYCERIN, LANSOPRAZOLE, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, ALBUTEROL SULFATE, ALBUTEROL, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, FLUTICASONE FUROATE, UMECLIDINIUM BROMIDE AND VILANTEROL TRIFENATATE, LIRAGLUTIDE,

25031226

CN

Bradycardia, Drug interaction,

METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, IVABRADINE,

25031364

DE

Generalised tonic-clonic seizure, Electrocardiogram QT prolonged, Drug interaction,

LEVOTHYROXINE SODIUM, LEVOTHYROXINE SODIUM ANHYDROUS, QUETIAPINE, QUETIAPINE, QUETIAPINE, FLUOXETINE HYDROCHLORIDE, FLUOXETINE HYDROCHLORIDE, ENALAPRIL MALEATE, ENALAPRIL,

25031426

ES

Non-cardiogenic pulmonary oedema, Drug interaction, Drug abuse, Toxicity to various agents, Intentional product misuse, Drug dependence, Overdose, Suicide attempt,

DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), FENTANYL, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, PROPOFOL, CLONAZEPAM, ALPRAZOLAM, ZOLPIDEM TARTRATE,

25031603

US

Mucosal inflammation, Acute kidney injury, Neutropenia, Thrombocytopenia, Oedema peripheral, Drug clearance decreased, Drug interaction,

IMATINIB, IMATINIB, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM,

25031719

US

Drug interaction,

APIXABAN, TUCATINIB, AMLODIPINE,

25031885

JP

Drug ineffective, Drug interaction, Aspartate aminotransferase increased, Fibrin D dimer increased, Drug level increased, Off label use,

CYCLOSPORINE, VENETOCLAX, VENETOCLAX, VENETOCLAX, VENETOCLAX, DANAZOL, AZACITIDINE, AZACITIDINE FOR,

25031971

Drug interaction, Seizure,

FLUOXETINE HYDROCHLORIDE,

25032157

GB

Drug interaction, Nervous system disorder,

25032335

ES

Cardioactive drug level increased, Atrioventricular block, Drug interaction, Bradycardia, Toxicity to various agents, Labelled drug-drug interaction issue,

POSACONAZOLE, DIGOXIN, LEVOFLOXACIN, LEVOFLOXACIN IN 5% DEXTROSE, EPLERENONE, FUROSEMIDE, CARVEDILOL, BISOPROLOL FUMARATE, RANITIDINE, RIVASTIGMINE, DECITABINE,

25032501

FR

Acute kidney injury, Drug interaction,

ZOLEDRONIC ACID, ZOLEDRONIC ACID, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, URSODIOL, URSOSIOL, URSODIOL, URSOSIOL, NEBIVOLOL, NEBIVOLOL HYDROCHLORIDE, NICARDIPINE HYDROCHLORIDE, NICARDIPINE, NICARDIPINE HYDROCHLORIDE, NICARDIPINE, FENOFIBRATE, REPAGLINIDE, INSULIN GLARGINE, ALLOPURINOL, ESCITALOPRAM OXALATE, ESCITALOPRAM,

25032868

GB

Death, Unresponsive to stimuli, Drug interaction, Dizziness,

CLARITHROMYCIN, RAMIPRIL, ALBUTEROL SULFATE, ALBUTEROL, APIXABAN, BUMETANIDE, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, FUROSEMIDE,

25032929

ES

Anaemia, Haematochezia, Drug interaction,

APIXABAN, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, AMIODARONE HYDROCHLORIDE,

25032948

FR

Atrial fibrillation, Drug interaction,

IBRUTINIB, APIXABAN, APIXABAN, BISOPROLOL FUMARATE, CANDESARTAN CILEXETIL, HYDROCHLOROTHIAZIDE, RABEPRAZOLE SODIUM, RABEPRAZOLE,

25033067

ES

Acute pulmonary oedema, Non-cardiogenic pulmonary oedema, Intentional product misuse, Drug abuse, Drug interaction, Toxicity to various agents, Overdose, Suicide attempt, Drug dependence,

FENTANYL, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, ALPRAZOLAM, ZOLPIDEM TARTRATE, PROPOFOL, CLONAZEPAM, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), NAPROXEN, NAPROXEN SODIUM,

25033144

US

Drug interaction, Product use in unapproved indication,

LIRAGLUTIDE,

25033204

PT

Serotonin syndrome, Drug interaction,

VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, ZOLPIDEM TARTRATE, LETROZOLE, LETROZOLE TABLETS, PREGABALIN,

25033256

CN

Ketoacidosis, Intestinal obstruction, Impaired gastric emptying, Drug interaction,

SEMAGLUTIDE, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG,

25028569

GB

Medication error, Drug interaction,

FLUOXETINE HYDROCHLORIDE, FLUOXETINE, CLOZAPINE,

25028634

ES

Drug interaction, Virologic failure,

LAMIVUDINE, LAMIVUDINE ORAL, RALTEGRAVIR, ALENDRONATE SODIUM, ALENDRONATE SODIUM TABLET, CALCIUM CARBONATE, ANTACID, CALCIFEDIOL,

25028642

ES

Hip fracture, Drug interaction,

DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, MIRTAZAPINE, LORAZEPAM,

25028725

TW

Bradycardia, Atrioventricular block complete, Sinus node dysfunction, Drug interaction, Toxicity to various agents,

TELMISARTAN, LITHIUM, LITHIUM BROMATUM, AMLODIPINE, VALPROATE SODIUM, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, ESTAZOLAM,

25028744

ES

Drug abuse, Non-cardiogenic pulmonary oedema, Intentional product misuse, Drug interaction, Overdose, Toxicity to various agents, Drug dependence,

ZOLPIDEM TARTRATE, QUETIAPINE FUMARATE, QUETIAPINE, VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE, ALPRAZOLAM, CLONAZEPAM, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), MORPHINE, NAPROXEN, NAPROXEN SODIUM, ONDANSETRON HYDROCHLORIDE, METOCLOPRAMIDE HYDROCHLORIDE, METHADONE, FENTANYL, FENTANYL, FENTANYL, PROPOFOL,

25028778

ES

Neurotoxicity, Drug interaction,

POSACONAZOLE, POSACONAZOLE DELAYED-RELEASE, QUIZARTINIB,

25026061

CA

Anxiety, Loss of personal independence in daily activities, Depression, Psychotic disorder, Tearfulness, Depressive symptom, Drug interaction, Paranoia, Psychiatric decompensation, Psychomotor skills impaired, Depression suicidal, Suicidal ideation,

LAMIVUDINE, LAMIVUDINE ORAL, ATAZANAVIR, BUPROPION HYDROCHLORIDE, BUPROPION, CLONAZEPAM, ENFUVIRTIDE, RALTEGRAVIR, LOPINAVIR AND RITONAVIR, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, RISPERIDONE, RITONAVIR, RITONAVIR 100 MG, SERTRALINE HYDROCHLORIDE, VALPROIC ACID, TENOFOVIR DISOPROXIL FUMARATE, EMTRICITABINE,

25026248

US

Leukaemia, Drug interaction,

UPADACITINIB,

25026295

FR

Hallucinations, mixed, Confusional state, Sinus tachycardia, Disorientation, Cognitive disorder, Mydriasis, Speech disorder, Toxicity to various agents, Intentional product misuse, Headache, Wrong technique in product usage process, Aspartate aminotransferase increased, Gamma-glutamyltransferase increased, Hyperkalaemia, Drug interaction,

VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, PAROXETINE HYDROCHLORIDE HEMIHYDRATE, PAROXETINE, PAROXETINE HYDROCHLORIDE, CITALOPRAM, CITALOPRAM HYDROBROMIDE, SERTRALINE, SERTRALINE, ARIPIPRAZOLE ORALLY DISINTEGRATING, ARIPIPRAZOLE, ARIPIPRAZOLE ORAL, ARIPIPRAZOLE ORALLY DISINTEGRATING, ARIPIPRAZOLE, ARIPIPRAZOLE ORAL, HYDROXYZINE, HYDROXYZINE, CETIRIZINE, CETIRIZINE HYDROCHLORIDE, CETIIRIZINE, RISPERIDONE,

25026309

PT

Serotonin syndrome, Drug interaction, Tremor, Hyperreflexia, Diarrhoea, Tachycardia, Hypertension, Pyrexia,

VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, ZOLPIDEM TARTRATE, LETROZOLE, LETROZOLE TABLETS, PREGABALIN, PREGABALIN, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE),

25026448

BE

Liver function test increased, Hepatitis, Drug interaction,

AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, IVACAFTOR, AMIKACIN, ALBUTEROL SULFATE,

25026531

CA

Loss of consciousness, Hypoaesthesia, Acne, Drug interaction, Dry skin, Feeling hot, Musculoskeletal stiffness, Formication, Flushing, Loss of consciousness, Rash pruritic, Menopausal symptoms, Menopausal symptoms, Rash pruritic, Formication, Skin burning sensation, Skin burning sensation, Hypoaesthesia, Anxiety, Urticaria, Urticaria, Acne, Musculoskeletal stiffness, Hot flush, Hot flush,

ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, DULOXETINE HYDROCHLORIDE, GABAPENTIN, DIMETHYL FUMARATE, DIMETHYL FUMARATE, DIMETHYL FUMARATE, DIMETHYL FUMARATE, DIMETHYL FUMARATE, DIMETHYL FUMARATE,

25026580

GB

Drug interaction, Medication error,

FLUOXETINE HYDROCHLORIDE, FLUOXETINE, CLOZAPINE,

25026587

AU

Myocarditis, Drug interaction, Treatment failure,

OLANZAPINE, OLANZAPINE, CLOZAPINE, CLOZAPINE, RISPERIDONE,

25021502

US

Adverse drug reaction, Psychiatric decompensation, Drug interaction,

CLOZAPINE,

25022613

US

Drug interaction,

APIXABAN, TUCATINIB, AMLODIPINE,

25022842

FR

Confusional state, Sinus tachycardia, Drug interaction, Toxicity to various agents, Hallucinations, mixed, Cognitive disorder, Mydriasis, Speech disorder, Headache, Wrong technique in product usage process, Aspartate aminotransferase increased, Gamma-glutamyltransferase increased, Disorientation, Hyperkalaemia,

ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, SERTRALINE, PAROXETINE HYDROCHLORIDE HEMIHYDRATE, PAROXETINE, PAROXETINE HYDROCHLORIDE, CITALOPRAM, CITALOPRAM HYDROBROMIDE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, RISPERIDONE, ARIPIPRAZOLE ORALLY DISINTEGRATING, ARIPIPRAZOLE, ARIPIPRAZOLE ORAL, HYDROXYZINE, CETIRIZINE, CETIRIZINE HYDROCHLORIDE, CETIIRIZINE, ARIPIPRAZOLE ORALLY DISINTEGRATING, ARIPIPRAZOLE, ARIPIPRAZOLE ORAL, HYDROXYZINE, SERTRALINE,

25022981

IN

Oculogyric crisis, Antipsychotic drug level increased, Drug interaction,

CLOZAPINE,

25022993

CA

Polymyositis, Drug interaction,

ATORVASTATIN CALCIUM, ATORVASTATIN CALCIUM, FILM COATED, NORTRIPTYLINE HYDROCHLORIDE, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM,

25022998

GB

Death, Drug interaction, Unresponsive to stimuli, Dizziness,

CLARITHROMYCIN, APIXABAN, BUMETANIDE, FUROSEMIDE, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, RAMIPRIL, ALBUTEROL SULFATE, ALBUTEROL,

25023542

DE

Generalised tonic-clonic seizure, Drug interaction, Focal dyscognitive seizures,

MIRTAZAPINE, MIRTAZAPINE, MIRTAZAPINE, MIRTAZAPINE, MIRTAZAPINE, MIRTAZAPINE, MIRTAZAPINE, MIRTAZAPINE, MIRTAZAPINE, MIRTAZAPINE, MIRTAZAPINE, MIRTAZAPINE, MIRTAZAPINE, MIRTAZAPINE, MIRTAZAPINE, MIRTAZAPINE, BISOPROLOL FUMARATE, BISOPROLOL FUMARATE, BISOPROLOL FUMARATE, BISOPROLOL FUMARATE, FUROSEMIDE, FUROSEMIDE, FUROSEMIDE, FUROSEMIDE, INSULIN HUMAN, INSULIN HUMAN, INSULIN HUMAN, INSULIN HUMAN,

25023609

GB

Drug interaction,

EPLERENONE, RAMIPRIL, DICLOFENAC SODIUM, DICLOFENAC SODIUM TOPICAL, DICLOFENAC SODIUM TOPICAL GEL, 1%, DICLOFENAC, DICLOFENAC SODIUM 1%, NITROGLYCERIN, CLOPIDOGREL, CLOPIDOGREL BISULFATE, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, FLUTICASONE FUROATE, UMECLIDINIUM BROMIDE AND VILANTEROL TRIFENATATE, LIRAGLUTIDE, CYANOCOBALAMIN, CYANOCOBALAMIN, ALBUTEROL SULFATE, ALBUTEROL, INSULIN GLARGINE-YFGN, INSULIN GLARGINE, LOSARTAN, LOSARTAN, AMITRIPTYLINE HYDROCHLORIDE, AMITRIPTYLINE HYDROCHLORIDE, APIXABAN, BISOPROLOL FUMARATE, LANSOPRAZOLE, DAPAGLIFLOZIN, FUROSEMIDE,

25023720

FR

Lactic acidosis, Drug interaction, Accidental overdose,

IRBESARTAN, HYDROCHLOROTHIAZIDE,

25023847

CH

Pancytopenia, Thrombocytopenia, Subdural haematoma, Drug interaction,

FLUOROURACIL, MITOMYCIN, MITOMYCIN,

25023899

US

Renal impairment, Condition aggravated, Hypertension, Drug interaction, Toxicity to various agents,

DARUNAVIR, DARUNAVIR 600 MG, DARUNAVIR 800 MG, RITONAVIR, RITONAVIR 100 MG, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, AZATHIOPRINE, DOLUTEGRAVIR SODIUM AND RILPIVIRINE HYDROCHLORIDE,

25024075

US

Drug interaction,

CELECOXIB, CELECOXIB, CELECOXIB, CELECOXIB,

25024105

GB

Drug interaction, Medication error,

FLUOXETINE HYDROCHLORIDE, FLUOXETINE, CLOZAPINE,

25024441

CH

Hypokalaemia, Hypomagnesaemia, Hypocalcaemia, Drug interaction,

OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, ALLOPURINOL, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL,

25024477

CA

Drug interaction, Atrial fibrillation, Chest discomfort, Escherichia infection, Off label use,

FLUCONAZOLE, MAVACAMTEN, CALCIUM, CANDESARTAN, ESOMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM, ESOMEPRAZOLE SODIUM, IRON, METOCLOPRAMIDE, METOCLOPRAMIDE HYDROCHLORIDE, NYSTATIN, NYSTATIN OINTMENT, NYSTATIN CREAM, RIVAROXABAN, ROSUVASTATIN, CYANOCOBALAMIN,

25024747

CN

Sjogren^s syndrome, Pulmonary embolism, Conjunctival haemorrhage, Coagulopathy, Gingival bleeding, Drug interaction,

ABEMACICLIB, RIVAROXABAN, RIVAROXABAN, RIVAROXABAN, RIVAROXABAN, RIVAROXABAN, LETROZOLE, LETROZOLE TABLETS, FENOFIBRATE, PROPAFENONE,

25024766

CA

Anticholinergic syndrome, Drug interaction,

OXYBUTYNIN, TOLTERODINE, HALOPERIDOL, HALOPERIDOL LACTATE, RISPERIDONE, QUETIAPINE FUMARATE, QUETIAPINE, MIRTAZAPINE, OLANZAPINE, LOPERAMIDE HYDROCHLORIDE, LOPERAMIDE HCL, RISPERIDONE, GALANTAMINE HYDROBROMIDE, TRAZODONE HYDROCHLORIDE, PAROXETINE HYDROCHLORIDE, RANITIDINE HYDROCHLORIDE, DONEPEZIL HYDROCHLORIDE, RIVASTIGMINE TARTRATE,

25025041

Multiple sclerosis relapse, Therapeutic product effect incomplete, Influenza like illness, Feeling abnormal, Rash erythematous, Rash pruritic, Acne, Infusion related reaction, Drug interaction,

OCRELIZUMAB,

25025120

US

Tooth abscess, Scratch, Influenza, Blood sodium decreased, Contusion, Asthenia, Nausea, Drug interaction,

SOMATROPIN, SOMATROPIN, PROMETHAZINE HYDROCHLORIDE,

25025434

GB

Nervous system disorder, Drug interaction,

25025495

FR

Rhabdomyolysis, Drug interaction,

CYCLOSPORINE,

25015403

Acute kidney injury, Cardiac failure congestive, Rhabdomyolysis, Drug interaction,

ROSUVASTATIN CALCIUM, ABIRATERONE ACETATE, ABIRATERONE, DENOSUMAB, PREDNISONE, CALCIFEDIOL, CALCIUM CARBONATE, ANTACID, BISOPROLOL FUMARATE, CETIRIZINE, CETIRIZINE HYDROCHLORIDE, CETIIRIZINE, LEVOTHYROXINE, CANDESARTAN, HYDROCHLOROTHIAZIDE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, TRIPTORELIN, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM,

25015520

Acute kidney injury, Rhabdomyolysis, Drug interaction,

ROSUVASTATIN CALCIUM, ABIRATERONE ACETATE, ABIRATERONE, PREDNISONE, METOPROLOL TARTRATE, METOPROLOL, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, ABIRATERONE ACETATE, ABIRATERONE,

25015798

GB

Dizziness, Nausea, Drug interaction,

OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, LANSOPRAZOLE, LEVOTHYROXINE,

25015803

CA

Fluid retention, Periorbital swelling, Intra-abdominal fluid collection, Weight increased, Drug interaction,

AVAPRITINIB, AVAPRITINIB, DASATINIB,

25015989

ES

Rhabdomyolysis, Drug interaction, Hypokalaemia,

ROSUVASTATIN, ROSUVASTATIN, ABIRATERONE ACETATE, ABIRATERONE, PREDNISONE, PREDNISONE,

25016072

Rhabdomyolysis, Drug interaction, Acute kidney injury,

ROSUVASTATIN CALCIUM, ABIRATERONE ACETATE, ABIRATERONE, PREDNISONE, PREDNISONE,

25016120

US

Drug interaction, Hypotension,

LISINOPRIL, LISINOPRIL, TIZANIDINE HYDROCHLORIDE, METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, HYDRALAZINE HYDROCHLORIDE, AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, DOXYCYCLINE, DOXYCYCLINE HYCLATE, CYCLOBENZAPRINE, CYCLOBENZAPRINE,

25017153

JO

Drug interaction, Myelosuppression, Diarrhoea,

ALLOPURINOL, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, AZATHIOPRINE,

25017384

ES

Bradycardia, Cardioactive drug level increased, Atrioventricular block, Drug interaction, Toxicity to various agents,

LEVOFLOXACIN, LEVOFLOXACIN IN 5% DEXTROSE, CARVEDILOL, EPLERENONE, FUROSEMIDE, POSACONAZOLE, DIGOXIN, DIGOXIN, RANITIDINE, RIVASTIGMINE, DECITABINE, BISOPROLOL FUMARATE,

25017678

GB

Cachexia, Drug dependence, Psychotic disorder, Anger, Memory impairment, Irritability, Depression, Aggression, Affective disorder, Back pain, Renal pain, Incoherent, Pallor, Mood swings, Decreased appetite, Drug interaction,

RAMIPRIL, TIRZEPATIDE, NAPROXEN, NAPROXEN SODIUM,

25017752

FR

Hypertensive crisis, Thrombotic microangiopathy, Renal impairment, Haematocrit decreased, Microangiopathy, Red blood cell count decreased, Drug interaction, Overdose,

RITONAVIR, RITONAVIR 100 MG, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, REMDESIVIR, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE,

25017766

DK

Drug level decreased, Drug interaction,

LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, NAPROXEN, NAPROXEN SODIUM, FLUCONAZOLE, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), MEROPENEM, LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE, LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE, LORAZEPAM, MIDAZOLAM, MIDAZOLAM HYDROCHLORIDE, MIDAZOLAM, MIDAZOLAM HYDROCHLORIDE, MIDAZOLAM, MIDAZOLAM HYDROCHLORIDE, TOPIRAMATE, TOPIRAMATE SPINKLE, MORPHINE, MORPHINE, MORPHINE, PHENOBARBITAL, PHENOBARBITAL, METRONIDAZOLE, METRONIDAZOLE TOPICAL, FENTANYL, PIPERACILLIN SODIUM AND TAZOBACTAM SODIUM, PIPERACILLIN AND TAZOBACTAM, PIPERACILLIN SODIUM,TAZOBACTAM SODIUM, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, ANIDULAFUNGIN, CLONIDINE, CLOBAZAM, DEXAMETHASONE, DEXAMETHASONE 1.5 MG, FOSPHENYTOIN, FOSPHENYTOIN SODIUM, ESOMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM, HALOPERIDOL, HALOPERIDOL LACTATE, HALOPERIDOL, HALOPERIDOL LACTATE, PROPOFOL, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, MELATONIN, VALPROIC ACID, VALPROIC ACID, VALPROIC ACID, VALPROIC ACID, VALPROIC ACID,

25017834

FR

Intentional product misuse, Toxicity to various agents, Sinus tachycardia, Drug interaction, Cognitive disorder, Confusional state, Mydriasis, Hallucinations, mixed, Headache,

PAROXETINE HYDROCHLORIDE HEMIHYDRATE, PAROXETINE, PAROXETINE HYDROCHLORIDE, ARIPIPRAZOLE ORALLY DISINTEGRATING, ARIPIPRAZOLE, ARIPIPRAZOLE ORAL, HYDROXYZINE, SERTRALINE, CITALOPRAM, CITALOPRAM HYDROBROMIDE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE,

25017836

US

Seizure, Toxicity to various agents, Mental status changes, Confusional state, Delirium, Multiple drug therapy, Drug interaction,

PAROXETINE HYDROCHLORIDE HEMIHYDRATE, PAROXETINE, PAROXETINE HYDROCHLORIDE, METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, LOSARTAN, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, DAPAGLIFLOZIN, INSULIN ASPART, INSULIN DEGLUDEC, LEVOTHYROXINE SODIUM, DOCUSATE SODIUM, DOCUSATE SODIUM 100MG, BISACODYL, BISACODYL SUPPOSITORIES, BISCODYL, POLYETHYLENE GLYCOL, FAMOTIDINE, MAGNESIUM OXIDE, ERGOCALCIFEROL, NIFEDIPINE, DOCUSATE SODIUM 50 MG AND SENNOSIDES 8.6 MG, DOCUSATE SODIUM, SENNOSIDES, DOCUSATE SODIUM, 50 MG SENNOSIDES, 8.6 MG, SENNOSIDES AND DOCUSATE SODIUM, LINACLOTIDE, RANOLAZINE, EXTENDED-RELEASE, RANOLAZINE, EXTENDED-RELEASE,

25018148

GB

Arrhythmia, Pulmonary oedema, Unresponsive to stimuli, Dyspnoea, Abdominal sepsis, Electrocardiogram QT prolonged, Drug interaction,

ERYTHROMYCIN, FLUCONAZOLE, ALBUMIN HUMAN, FUROSEMIDE,

25018204

IN

Delirium, Loss of consciousness, Encephalitis, Psychotic disorder, Nystagmus, Toxicity to various agents, Dry skin, Gingival hypertrophy, Ataxia, Stupor, Drug interaction,

ISONIAZID, ISONIAZID, RIFAMPIN, ETHAMBUTOL HYDROCHLORIDE, PHENYTOIN, LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE,