Drug Search by Year (Detail)

25018262

GB

Drug interaction,

RAMIPRIL, EPLERENONE, CYANOCOBALAMIN, LIRAGLUTIDE, LOSARTAN, LANSOPRAZOLE, FLUTICASONE FUROATE, UMECLIDINIUM BROMIDE AND VILANTEROL TRIFENATATE, BISOPROLOL FUMARATE, INSULIN GLARGINE-YFGN, INSULIN GLARGINE, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, ALBUTEROL SULFATE, ALBUTEROL, DAPAGLIFLOZIN, DICLOFENAC SODIUM, DICLOFENAC SODIUM TOPICAL, DICLOFENAC SODIUM TOPICAL GEL, 1%, DICLOFENAC, DICLOFENAC SODIUM 1%, FUROSEMIDE, AMITRIPTYLINE HYDROCHLORIDE, APIXABAN, NITROGLYCERIN, CLOPIDOGREL, CLOPIDOGREL BISULFATE,

25018275

ES

Drug interaction, Seizure,

PIPERACILLIN SODIUM,TAZOBACTAM SODIUM, LINEZOLID, CITALOPRAM, CITALOPRAM HYDROBROMIDE,

25018276

GB

Drug interaction, Blindness, Dizziness,

FLUCONAZOLE, IVABRADINE,

25018353

GB

Labelled drug-drug interaction medication error, Drug interaction, Drug clearance decreased, Chemotherapeutic drug level increased, Mucosal inflammation,

METHOTREXATE SODIUM, PIPERACILLIN SODIUM AND TAZOBACTAM SODIUM, PIPERACILLIN AND TAZOBACTAM, PIPERACILLIN SODIUM,TAZOBACTAM SODIUM,

25018437

US

Loss of consciousness, Middle insomnia, Vertigo, Feeling abnormal, Insomnia, Initial insomnia, Hypophagia, Sleep deficit, Blood potassium decreased, Blood calcium increased, Fatigue, Restlessness, Drug interaction, Somnolence, Dizziness, Vomiting, Nausea, Weight decreased, Muscle spasms, Drug ineffective, Product dose omission issue, Wrong technique in product usage process,

SODIUM OXYBATE, SODIUM OXYBATE, SODIUM OXYBATE, SODIUM OXYBATE, SODIUM OXYBATE, SODIUM OXYBATE, SODIUM OXYBATE, SODIUM OXYBATE, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, SEMAGLUTIDE, LITHIUM, LITHIUM BROMATUM, CLONAZEPAM, CLONAZEPAM, QUETIAPINE, PROPRANOLOL HYDROCHLORIDE, METHYLPHENIDATE, METHYLPHENIDATE HYDROCHLORIDE, MODAFINIL, PITOLISANT HYDROCHLORIDE, LITHIUM CARBONATE, VALACYCLOVIR HYDROCHLORIDE, PROMETHAZINE, PROMETHAZINE, PROMETHAZINE, HYOSCYAMINE SULFATE, HYOSCYAMINE SULFATE, HYOSCYAMINE SULFATE, LEVONORGESTREL,

25018982

US

Drug interaction, Anxiety, Nausea,

SODIUM OXYBATE, SODIUM OXYBATE, SODIUM OXYBATE, SODIUM OXYBATE, FLUOXETINE HYDROCHLORIDE,

25019169

BE

Hepatitis, Liver function test increased, Drug interaction,

IVACAFTOR, AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, AMIKACIN, ALBUTEROL SULFATE,

25019177

AU

Drug interaction,

RIFABUTIN, IMIPENEM AND CILASTATIN SODIUM, IMIPENEM AND CILASTATIN, AMPICILLIN, AMPICILLIN SODIUM, AMPICILLIN INJECTION, AMIKACIN, AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE,

25019281

ES

Urinary tract infection enterococcal, Drug interaction,

ANTI-THYMOCYTE GLOBULIN (RABBIT), METHYLPREDNISOLONE, PREDNISONE, MYCOPHENOLIC ACID, MYCOPHENILIC ACID, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, FEBUXOSTAT, FEBUXOSTAT TABLETS 40 MG, FEBUXOSTAT TABLETS 80 MG,

25019962

FR

Toxicity to various agents, Drug interaction, Asthenia, Taste disorder, Dyspnoea, Fatigue, Decreased appetite,

ESOMEPRAZOLE MAGNESIUM, ESOMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM DELAYED RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, VORICONAZOLE, POSACONAZOLE, POSACONAZOLE DELAYED-RELEASE,

25020036

FR

Acute kidney injury, Drug interaction,

MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, ALLOPURINOL, URSODIOL, URSOSIOL, FENOFIBRATE, INSULIN GLARGINE, NICARDIPINE HYDROCHLORIDE, NICARDIPINE, REPAGLINIDE, ESCITALOPRAM OXALATE, ESCITALOPRAM, NEBIVOLOL, NEBIVOLOL HYDROCHLORIDE, ZOLEDRONIC ACID, ZOLEDRONIC ACID,

25020165

US

Drug interaction,

TUCATINIB, TUCATINIB, APIXABAN,

25020170

US

Drug interaction,

ETRASIMOD, ESCITALOPRAM,

25011348

PL

Convulsive threshold lowered, Serotonin syndrome, Delirium, Seizure, Drug interaction, Altered state of consciousness, Parasomnia, Respiratory depression, Abdominal pain upper, Sedation, Confusional state, Oedema peripheral, Hyperhidrosis, Diarrhoea, Vomiting, Nausea, Drug intolerance, Therapeutic product effect decreased,

ALPRAZOLAM, BUPRENORPHINE, CELECOXIB, CLARITHROMYCIN, CHLORPROMAZINE, CLORAZEPATE DIPOTASSIUM, DULOXETINE HYDROCHLORIDE, DULOXETINE, FLUCONAZOLE, FLUOXETINE HYDROCHLORIDE, FLUOXETINE, METOPROLOL TARTRATE, METOPROLOL, METHADONE, METOCLOPRAMIDE, METOCLOPRAMIDE HYDROCHLORIDE, METRONIDAZOLE, METRONIDAZOLE TOPICAL, MIRTAZAPINE, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, PAROXETINE HYDROCHLORIDE HEMIHYDRATE, PAROXETINE, PAROXETINE HYDROCHLORIDE, PALONOSETRON, PALONOSETRON HYDROCHLORIDE, PROMETHAZINE, TRAMADOL HYDROCHLORIDE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, ZOLPIDEM TARTRATE,

25011393

US

Drug interaction,

APALUTAMIDE, RELUGOLIX,

25011499

FR

Drug interaction, Therapeutic product effect decreased,

ENZALUTAMIDE, OXYCODONE HYDROCHLORIDE,

25011546

ES

Hip fracture, Drug interaction,

VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, MIRTAZAPINE, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), LORAZEPAM,

25011548

ES

Bradycardia, Cardioactive drug level increased, Atrioventricular block, Drug interaction, Toxicity to various agents,

LEVOFLOXACIN, LEVOFLOXACIN IN 5% DEXTROSE, EPLERENONE, FUROSEMIDE, CARVEDILOL, POSACONAZOLE, DIGOXIN, DIGOXIN, POSACONAZOLE, POSACONAZOLE DELAYED-RELEASE, DECITABINE, BISOPROLOL FUMARATE, RANITIDINE, RIVASTIGMINE,

25011843

US

Chronic lymphocytic leukaemia, Drug interaction, Drug ineffective,

NATALIZUMAB, ACALABRUTINIB,

25011859

Sinusitis, Ear infection, Chest discomfort, Balance disorder, Tremor, Hyperhidrosis, Dizziness, Drug interaction,

DEXTROMETHORPHAN HYDROBROMIDE, BUPROPION HYDROCHLORIDE, DEXTROMETHORPHAN HYDROBROMIDE, BUPROPION HYDROCHLORIDE, DEXTROMETHORPHAN HYDROBROMIDE, BUPROPION HYDROCHLORIDE, DEXTROMETHORPHAN HYDROBROMIDE, BUPROPION HYDROCHLORIDE, CEFDINIR, MESALAMINE, ARIPIPRAZOLE ORALLY DISINTEGRATING, ARIPIPRAZOLE, ARIPIPRAZOLE ORAL, ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, BUDESONIDE,

25011983

TW

Atrioventricular block complete, Bradycardia, Toxicity to various agents, Drug interaction,

LITHIUM, LITHIUM BROMATUM, LITHIUM, LITHIUM BROMATUM, AMLODIPINE, VALPROATE SODIUM, VALPROATE SODIUM, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, ESTAZOLAM, ESTAZOLAM, TELMISARTAN,

25012249

US

Drug interaction,

MAVACAMTEN, HYDROCORTISONE, ANTIPRURITIC (ANTI-ITCH), ANTI-ITCH CREAM, HYDROCORTISONE 1%, HYDROCORTISONE CONTINUOUS SPRAY, ANTI-PRURITIC, HYDROCORTISONE LOTION, HYDROCORTISONE ACETATE, HYDROCORTISONE LOTION KIT, ANTI ITCH, ANTI-ITCH, COOL RELIEF GEL WITH ALOE, HYDROCORTISONE CREAM 1%, HYDROCORTISONE SPRAY, DRS. HYDROCORTISONE,

25012293

CA

Anticholinergic syndrome, Drug interaction,

OLANZAPINE, RISPERIDONE, LOPERAMIDE HYDROCHLORIDE, LOPERAMIDE HCL, GALANTAMINE HYDROBROMIDE, RIVASTIGMINE TARTRATE, OXYBUTYNIN, MIRTAZAPINE, HALOPERIDOL, HALOPERIDOL LACTATE, QUETIAPINE FUMARATE, QUETIAPINE, TRAZODONE HYDROCHLORIDE, RISPERIDONE, PAROXETINE HYDROCHLORIDE, RANITIDINE HYDROCHLORIDE, DONEPEZIL HYDROCHLORIDE, TOLTERODINE,

25012296

FR

Intentional product misuse, Toxicity to various agents, Confusional state, Sinus tachycardia, Drug interaction, Cognitive disorder, Mydriasis, Hallucinations, mixed, Headache,

CITALOPRAM, CITALOPRAM HYDROBROMIDE, PAROXETINE HYDROCHLORIDE HEMIHYDRATE, PAROXETINE, PAROXETINE HYDROCHLORIDE, SERTRALINE, ARIPIPRAZOLE ORALLY DISINTEGRATING, ARIPIPRAZOLE, ARIPIPRAZOLE ORAL, HYDROXYZINE, VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE,

25012440

US

Weight increased, Inappropriate schedule of product administration, Drug interaction, Therapeutic product effect incomplete,

FREMANEZUMAB-VFRM, OBINUTUZUMAB, DOXORUBICIN, PREDNISONE, RIZATRIPTAN,

25012731

PL

Ischaemic stroke, Drug interaction,

DARATUMUMAB, LENALIDOMIDE, DEXAMETHASONE, DEXAMETHASONE 1.5 MG,

25013037

US

Drug interaction,

GUSELKUMAB, GUSELKUMAB, GUSELKUMAB, GUSELKUMAB, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM,

25013725

US

Dysstasia, Memory impairment, Swelling face, Drug interaction, Brain fog, Asthenia, Fatigue, Diarrhoea, Peripheral swelling,

LEVETIRACETAM,

25014028

GB

Drug interaction,

CLARITHROMYCIN, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, DOXAZOSIN, DOXAZOSIN MESYLATE, SIMVASTATIN, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, BISOPROLOL FUMARATE,

25014054

ES

Somnolence, Product name confusion, Drug interaction,

METOCLOPRAMIDE HYDROCHLORIDE,

25014146

GB

Drug interaction, Blindness, Dizziness,

AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, IVABRADINE, LEVOTHYROXINE,

25014656

US

Drug interaction,

TUCATINIB, APIXABAN, AMLODIPINE,

25014877

ES

Pregnancy with implant contraceptive, Unintended pregnancy, Tuberculin test positive, Drug interaction, Device breakage, Drug ineffective,

ETONOGESTREL, RIFAMPIN,

25014906

US

Seizure, Medical device battery replacement, Drug interaction,

FENFLURAMINE, FENFLURAMINE, FENFLURAMINE, FENFLURAMINE, FENFLURAMINE, PAROXETINE HYDROCHLORIDE HEMIHYDRATE, PAROXETINE, PAROXETINE HYDROCHLORIDE, PAROXETINE HYDROCHLORIDE HEMIHYDRATE, PAROXETINE, PAROXETINE HYDROCHLORIDE,

25014984

US

Drug interaction,

APIXABAN, TUCATINIB,

25014986

FR

Drug interaction, Hyponatraemia,

SPIRONOLACTONE,

25015002

US

Mucosal inflammation, Drug clearance decreased, Oedema peripheral, Drug interaction,

IMATINIB, METHOTREXATE, METHOTREXATE SODIUM,

25015006

US

Toxicity to various agents, Drug interaction, Maternal exposure during pregnancy, Off label use,

TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, ABACAVIR SULFATE, ABACAVIR, FENTANYL, MAGNESIUM, MAGNESIUM, RIFAMPIN, BICTEGRAVIR SODIUM, EMTRICITABINE, AND TENOFOVIR ALAFENAMIDE FUMARATE, MAGNESIUM SULFATE, MAGNESIUM SULFATE HEPTAHYDRATE, MAGNESIUM SULFATE IN WATER FOR, MAGNESIUM SULFATE, MAGNESIUM SULFATE HEPTAHYDRATE, MAGNESIUM SULFATE IN WATER FOR, MAGNESIUM SULFATE, MAGNESIUM SULFATE HEPTAHYDRATE, MAGNESIUM SULFATE IN WATER FOR, AZATHIOPRINE, DOLUTEGRAVIR SODIUM AND RILPIVIRINE HYDROCHLORIDE, RITONAVIR, RITONAVIR 100 MG, DARUNAVIR, DARUNAVIR 600 MG, DARUNAVIR 800 MG, LAMIVUDINE, LAMIVUDINE ORAL, NICARDIPINE, LABETALOL,

25015013

US

Hot flush, Heart rate decreased, Nocturia, Dizziness, Palpitations, Emotional disorder, Drug interaction, Middle insomnia, Erectile dysfunction, Brain fog, Fatigue, General physical condition abnormal, Depression, Headache,

NEBIVOLOL HYDROCHLORIDE, RELUGOLIX, RELUGOLIX,

25015129

IL

Ascites, Pericardial effusion, Atrial fibrillation, Ejection fraction decreased, Drug interaction,

PALBOCICLIB, GOSERELIN, APIXABAN, PREDNISONE, TACROLIMUS, BISOPROLOL FUMARATE, LEVOTHYROXINE, ATORVASTATIN CALCIUM, FULVESTRANT,

25015250

ES

Rhabdomyolysis, Drug interaction, Hypokalaemia, Renal impairment,

ABIRATERONE ACETATE, ROSUVASTATIN, PREDNISONE,

25006712

PT

Drug interaction, Myopathy,

DEXAMETHASONE, DEXAMETHASONE 1.5 MG, TUCATINIB,

25006752

US

Cardiac amyloidosis, Pericardial effusion, Myalgia, Drug interaction,

ROSUVASTATIN, TAFAMIDIS,

25006766

CA

Hallucination, auditory, Drug interaction, Depression,

OLANZAPINE, RALTEGRAVIR, CITALOPRAM, CITALOPRAM HYDROBROMIDE, EMTRICITABINE,

25006843

SE

Drug interaction, Rhabdomyolysis, Acute kidney injury,

LINAGLIPTIN, GABAPENTIN, ROSUVASTATIN CALCIUM,

25006867

DK

Drug level below therapeutic, Drug interaction, Anticonvulsant drug level decreased,

LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, VALPROIC ACID, VALPROIC ACID, VALPROIC ACID, VALPROIC ACID, TOPIRAMATE, TOPIRAMATE SPINKLE, FOSPHENYTOIN, FOSPHENYTOIN SODIUM, MEROPENEM, MEROPENEM, MEROPENEM, PHENOBARBITAL, PHENOBARBITAL, ESOMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, CLONIDINE, DEXAMETHASONE, DEXAMETHASONE 1.5 MG, ANIDULAFUNGIN, ANIDULAFUNGIN, NAPROXEN, NAPROXEN SODIUM, BACLOFEN, FENTANYL, PROPOFOL, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, GABAPENTIN, MORPHINE, MORPHINE, CLONAZEPAM, LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE, LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE, HALOPERIDOL, HALOPERIDOL LACTATE, HALOPERIDOL, HALOPERIDOL LACTATE, LORAZEPAM, CLOBAZAM, MELATONIN, AMPICILLIN, AMPICILLIN SODIUM, AMPICILLIN INJECTION, PENICILLIN G, PIPERACILLIN SODIUM,TAZOBACTAM SODIUM, MEROPENEM, GENTAMICIN, GENTAMICIN SULFATE, METRONIDAZOLE, METRONIDAZOLE TOPICAL, FLUCONAZOLE, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), MIDAZOLAM, MIDAZOLAM HYDROCHLORIDE,

25006883

US

Hypotension, Drug interaction,

TIZANIDINE, LISINOPRIL, METOPROLOL TARTRATE, METOROPROLOL TARTRATE, METOPROLOL, HYDRALAZINE HYDROCHLORIDE, HYDROCHLOROTHIAZIDE,

25006982

GB

Drug interaction, Medication error,

FLUOXETINE HYDROCHLORIDE, FLUOXETINE, CLOZAPINE,

25007036

Drug interaction, Bone tuberculosis, Condition aggravated, Immunosuppression, Product use in unapproved indication,

METHOTREXATE SODIUM, PREDNISONE, ADALIMUMAB,

25007160

CA

Foot fracture, Weight decreased, Intentional product use issue, Drug interaction, Off label use,

HUMAN IMMUNOGLOBULIN G, RITUXIMAB-PVVR, RITUXIMAB-PVVR, IRON,

25007466

TW

Atrioventricular block complete, Bradycardia, Drug interaction, Toxicity to various agents, Sinus node dysfunction,

TELMISARTAN, LITHIUM, LITHIUM BROMATUM, VALPROATE SODIUM, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, ESTAZOLAM, AMLODIPINE,

25007624

US

Drug interaction,

RIFAMPIN, APIXABAN,

25008182

IN

Oculogyric crisis, Antipsychotic drug level increased, Drug interaction,

CLOZAPINE, CLOZAPINE,

25008247

NL

Ovarian cyst, Ovarian operation, Drug interaction,

ARIPIPRAZOLE,

25008329

DE

Generalised tonic-clonic seizure, Fall, Spinal fracture, Insomnia, Multiple fractures, Drug interaction,

SERTRALINE HYDROCHLORIDE, SERTRALINE HYDROCHLORIDE, SERTRALINE HYDROCHLORIDE, SERTRALINE HYDROCHLORIDE, QUETIAPINE FUMARATE, QUETIAPINE, QUETIAPINE FUMARATE, QUETIAPINE, QUETIAPINE FUMARATE, QUETIAPINE, QUETIAPINE FUMARATE, QUETIAPINE, LORAZEPAM, LORAZEPAM, LORAZEPAM, LORAZEPAM, LORAZEPAM, LORAZEPAM, LORAZEPAM, LORAZEPAM,

25008508

AU

Myocarditis, Drug interaction, Treatment failure, Extrapyramidal disorder, Mania,

CLOZAPINE, OLANZAPINE, RISPERIDONE,

25008513

AU

Myocarditis, Drug interaction, Treatment failure, Off label use,

CLOZAPINE, OLANZAPINE, PALIPERIDONE,

25008514

AU

Myocarditis, Drug interaction, Treatment failure, Off label use,

CLOZAPINE, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, PAROXETINE HYDROCHLORIDE HEMIHYDRATE, PAROXETINE, PAROXETINE HYDROCHLORIDE, AMISULPRIDE, ARIPIPRAZOLE ORALLY DISINTEGRATING, ARIPIPRAZOLE, ARIPIPRAZOLE ORAL, OLANZAPINE, ASENAPINE, ASENAPINE MALEATE, PALIPERIDONE,

25008548

US

Serotonin syndrome, Completed suicide, Drug abuse, Compulsive sexual behaviour, Toxicity to various agents, Substance-induced psychotic disorder, Homicide, Drug interaction,

FLUOXETINE HYDROCHLORIDE, FLUOXETINE, DEXTROMETHORPHAN,

25008581

IN

Psychotic disorder, Drug interaction, Drug resistance,

RIFAMPIN, CYCLOSERINE, ISONIAZID,

25008638

ES

Hip fracture, Drug interaction,

LORAZEPAM, VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), MIRTAZAPINE,

25008940

US

Diarrhoea, Drug interaction,

SELEXIPAG, CLOPIDOGREL, CLOPIDOGREL BISULFATE,

25009063

ES

Non-cardiogenic pulmonary oedema, Acute pulmonary oedema, Drug abuse, Intentional product misuse, Toxicity to various agents, Drug interaction, Overdose, Drug dependence, Suicide attempt,

PROPOFOL, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), ALPRAZOLAM, ALPRAZOLAM, ALPRAZOLAM, ALPRAZOLAM, ALPRAZOLAM, ALPRAZOLAM, ALPRAZOLAM, CLONAZEPAM, FENTANYL, FENTANYL, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, ZOLPIDEM TARTRATE, ZOLPIDEM TARTRATE,

25009439

DK

Drug interaction, Drug level below therapeutic, Therapeutic product effect incomplete,

MEROPENEM, VALPROIC ACID, TOPIRAMATE, TOPIRAMATE SPINKLE, LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, PHENOBARBITAL, FOSPHENYTOIN, FOSPHENYTOIN SODIUM, CLONAZEPAM, LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE, LORAZEPAM, CLOBAZAM, MIDAZOLAM, MIDAZOLAM HYDROCHLORIDE,

25009746

FR

Lactic acidosis, Drug interaction, Accidental overdose,

IRBESARTAN, HYDROCHLOROTHIAZIDE,

25009864

US

Drug interaction,

TUCATINIB,

25010064

ES

Melaena, Drug interaction,

TICAGRELOR, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG,

25010131

ES

Gastroenteritis, Drug interaction,

TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, PREDNISONE, PREDNISONE, PREDNISONE, PREDNISONE,

25010135

CA

Depression, Drug interaction,

QUETIAPINE FUMARATE, QUETIAPINE, LOPINAVIR AND RITONAVIR, BUPROPION HYDROCHLORIDE, BUPROPION, ATAZANAVIR SULFATE, ATAZANAVIR, SERTRALINE HYDROCHLORIDE, CLONAZEPAM, VALPROATE SODIUM, LAMIVUDINE, LAMIVUDINE ORAL, EFAVIRENZ,

25010278

IL

Ascites, Atrial fibrillation, Pericardial effusion, Therapy partial responder, Drug interaction,

LETROZOLE, LETROZOLE TABLETS, GOSERELIN, APIXABAN, PREDNISONE, TACROLIMUS, BISOPROLOL FUMARATE, LEVOTHYROXINE, ATORVASTATIN CALCIUM, PALBOCICLIB, FULVESTRANT,

25010467

FR

Inflammation, Hepatotoxicity, Nephropathy toxic, Multiple organ dysfunction syndrome, COVID-19, Drug interaction,

ESOMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, VORICONAZOLE, POSACONAZOLE, POSACONAZOLE DELAYED-RELEASE,

25010528

PT

Hyperhidrosis, Agitation, Drug interaction, Diarrhoea, Depressed mood, Fatigue, Decreased interest, Tremor, Insomnia, Disturbance in attention, Feelings of worthlessness, Suicidal ideation, Hyperreflexia, Clonus, Tachycardia, Hypertension, Pyrexia, Serotonin syndrome,

TRAMADOL HYDROCHLORIDE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, ZOLPIDEM TARTRATE, LETROZOLE, LETROZOLE TABLETS, PREGABALIN, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE),

25010761

US

Cardiomyopathy, Atrial fibrillation, Cardiac failure, Drug interaction,

OMAVELOXOLONE, OMAVELOXOLONE, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES,

25001833

CA

Depression suicidal, Drug interaction, Loss of personal independence in daily activities, Paranoia, Psychiatric decompensation, Intentional product use issue, Prescribed overdose, Incorrect route of product administration, Tearfulness, Psychomotor skills impaired, Psychotic disorder, Suicidal ideation, Depressive symptom, Anxiety, Depression,

CLONAZEPAM, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, RISPERIDONE, VALPROIC ACID, SERTRALINE, ATAZANAVIR, LAMIVUDINE, LAMIVUDINE ORAL, BUPROPION HYDROCHLORIDE, BUPROPION, ENFUVIRTIDE, RALTEGRAVIR, LOPINAVIR AND RITONAVIR, RITONAVIR, RITONAVIR 100 MG, TENOFOVIR DISOPROXIL FUMARATE, EMTRICITABINE,

25001871

US

Completed suicide, Serotonin syndrome, Substance-induced psychotic disorder, Drug interaction, Toxicity to various agents, Compulsive sexual behaviour, Homicide,

FLUOXETINE HYDROCHLORIDE, FLUOXETINE, DEXTROMETHORPHAN,

25001902

ES

Hip fracture, Drug interaction,

MIRTAZAPINE, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), LORAZEPAM, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE,

25002058

CA

Anticholinergic syndrome, Drug interaction,

RANITIDINE, DONEPEZIL HYDROCHLORIDE, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, GALANTAMINE, HALOPERIDOL, HALOPERIDOL LACTATE, MIRTAZAPINE, OLANZAPINE, OXYBUTYNIN, PAROXETINE HYDROCHLORIDE HEMIHYDRATE, PAROXETINE, PAROXETINE HYDROCHLORIDE, RISPERIDONE, RIVASTIGMINE, TOLTERODINE, RISPERIDONE,

25002695

GB

Drug interaction,

LOSARTAN, DICLOFENAC SODIUM, DICLOFENAC SODIUM TOPICAL, DICLOFENAC SODIUM TOPICAL GEL, 1%, DICLOFENAC, DICLOFENAC SODIUM 1%, APIXABAN, CYANOCOBALAMIN, BISOPROLOL FUMARATE, LANSOPRAZOLE, INSULIN GLARGINE-YFGN, INSULIN GLARGINE, AMITRIPTYLINE HYDROCHLORIDE, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, CLOPIDOGREL, CLOPIDOGREL BISULFATE, LIRAGLUTIDE, FLUTICASONE FUROATE, UMECLIDINIUM BROMIDE AND VILANTEROL TRIFENATATE, FUROSEMIDE, ALBUTEROL SULFATE, ALBUTEROL, EPLERENONE, NITROGLYCERIN, DAPAGLIFLOZIN,

25002921

US

Serotonin syndrome, Parkinsonism, Drug interaction,

BUPROPION HYDROCHLORIDE, ALBUTEROL SULFATE, ALBUTEROL, ROPINIROLE, RANITIDINE, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, MORPHINE, SUVOREXANT, TIZANIDINE, BUDESONIDE, GABAPENTIN, CLONAZEPAM,

25002931

DK

Anticonvulsant drug level below therapeutic, Drug interaction,

TOPIRAMATE, TOPIRAMATE SPINKLE, MEROPENEM, PHENOBARBITAL, VALPROIC ACID, VALPROIC ACID, VALPROIC ACID, VALPROIC ACID, VALPROIC ACID, LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, FOSPHENYTOIN, FOSPHENYTOIN SODIUM, PHENOBARBITAL, ESOMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, CLONIDINE, DEXAMETHASONE, DEXAMETHASONE 1.5 MG, PIPERACILLIN SODIUM,TAZOBACTAM SODIUM, METRONIDAZOLE, METRONIDAZOLE TOPICAL, FLUCONAZOLE, ANIDULAFUNGIN, NAPROXEN, NAPROXEN SODIUM, FENTANYL, PROPOFOL, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, MORPHINE, MORPHINE, LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE, LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE, HALOPERIDOL, HALOPERIDOL LACTATE, HALOPERIDOL, HALOPERIDOL LACTATE, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), LORAZEPAM, CLOBAZAM, MIDAZOLAM, MIDAZOLAM HYDROCHLORIDE, MIDAZOLAM, MIDAZOLAM HYDROCHLORIDE, MELATONIN, AMPICILLIN, AMPICILLIN SODIUM, AMPICILLIN INJECTION, PENICILLIN G, GENTAMICIN, GENTAMICIN SULFATE, CERLIPONASE ALFA,

25002937

US

Serotonin syndrome, Substance-induced psychotic disorder, Completed suicide, Drug interaction, Drug abuse, Toxicity to various agents, Compulsive sexual behaviour, Homicide,

FLUOXETINE HYDROCHLORIDE, FLUOXETINE, DEXTROMETHORPHAN,

25002941

AU

Suicidal ideation, Insomnia, Lethargy, Akathisia, Blood prolactin increased, Drug interaction, Affect lability, Depressed mood, Treatment failure,

CABERGOLINE, ARIPIPRAZOLE ORALLY DISINTEGRATING, ARIPIPRAZOLE, ARIPIPRAZOLE ORAL, ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, ESOMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM, CABERGOLINE, ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, CABERGOLINE,

25003156

DK

Anticonvulsant drug level decreased, Drug interaction,

MEROPENEM, MEROPENEM, VALPROIC ACID, VALPROIC ACID, VALPROIC ACID, VALPROIC ACID, LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, TOPIRAMATE, TOPIRAMATE SPINKLE, FOSPHENYTOIN, FOSPHENYTOIN SODIUM, PHENOBARBITAL, PHENOBARBITAL, GENTAMICIN, GENTAMICIN SULFATE, AMPICILLIN, AMPICILLIN SODIUM, AMPICILLIN INJECTION, PENICILLIN G, ESOMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, CLONIDINE, DEXAMETHASONE, DEXAMETHASONE 1.5 MG, PIPERACILLIN SODIUM,TAZOBACTAM SODIUM, METRONIDAZOLE, METRONIDAZOLE TOPICAL, FLUCONAZOLE, ANIDULAFUNGIN, ANIDULAFUNGIN, NAPROXEN, NAPROXEN SODIUM, FENTANYL, PROPOFOL, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, MORPHINE, MORPHINE, LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE, LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE, HALOPERIDOL, HALOPERIDOL LACTATE, HALOPERIDOL, HALOPERIDOL LACTATE, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), LORAZEPAM, CLOBAZAM, MIDAZOLAM, MIDAZOLAM HYDROCHLORIDE, MIDAZOLAM, MIDAZOLAM HYDROCHLORIDE, MIDAZOLAM, MIDAZOLAM HYDROCHLORIDE, MELATONIN, MEROPENEM, BACLOFEN, GABAPENTIN, CLONAZEPAM,

25003227

US

Drug interaction, Renal impairment, Condition aggravated, Hypertension, Toxicity to various agents, Exposure during pregnancy,

DARUNAVIR, DARUNAVIR 600 MG, DARUNAVIR 800 MG, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, RITONAVIR, RITONAVIR 100 MG, AZATHIOPRINE, DOLUTEGRAVIR SODIUM AND RILPIVIRINE HYDROCHLORIDE,

25003908

US

Electrocardiogram QT prolonged, Syncope, Cardiac murmur, Drug interaction,

25004645

GB

Death, Cholelithiasis, Arrhythmia, Electrocardiogram QT prolonged, Drug interaction, Pulmonary oedema, Unresponsive to stimuli, Abdominal sepsis, Pancreatitis necrotising, Abdominal pain, Dyspnoea,

FLUCONAZOLE, FLUCONAZOLE, ERYTHROMYCIN, ALBUMIN HUMAN, FUROSEMIDE,

25004750

ES

COVID-19 pneumonia, Drug interaction,

TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, MYCOPHENOLIC ACID, MYCOPHENILIC ACID, PREDNISONE,

25005020

US

Toxic epidermal necrolysis, Drug interaction, Product use in unapproved indication,

CARBOPLATIN, PEMBROLIZUMAB, PACLITAXEL, DUPILUMAB, DUPILUMAB, CISPLATIN,

25005262

GB

Drug interaction, Overdose,

BENRALIZUMAB, THEOPHYLLINE ANHYDROUS, THEOPHYLLINE,

25005295

TR

Diplopia, Prosopagnosia, Myoclonus, Drug interaction, Restlessness, Agitation, Product use in unapproved indication,

HYDROXYCHLOROQUINE, HYDROXYCHLOROQUINE, HYDROXYCHLOROQUINE, CLARITHROMYCIN, METHYLPREDNISOLONE, CEFTRIAXONE, CEFTRIAXONE SODIUM,

25005350

CN

Anaphylactic shock, Drug interaction,

LIDOCAINE HYDROCHLORIDE, LIDOCAINE HYDROCHLORIDE ANHYDROUS,

25005351

CA

Anxiety, Depression, Depression suicidal, Depressive symptom, Drug interaction, Loss of personal independence in daily activities, Paranoia, Psychiatric decompensation, Psychomotor skills impaired, Psychotic disorder, Suicidal ideation, Tearfulness, Hospitalisation,

ATAZANAVIR SULFATE, ATAZANAVIR, LAMIVUDINE, LAMIVUDINE ORAL, BUPROPION HYDROCHLORIDE, BUPROPION, CLONAZEPAM, EMTRICITABINE, ENFUVIRTIDE, RALTEGRAVIR, LOPINAVIR AND RITONAVIR, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, RISPERIDONE, RITONAVIR, RITONAVIR 100 MG, SERTRALINE, VALPROIC ACID, TENOFOVIR DISOPROXIL FUMARATE,

25005559

NL

Drug interaction, Tinnitus, Palpitations, Headache, Fatigue,

ESOMEPRAZOLE MAGNESIUM, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, AZATHIOPRINE, INFLIXIMAB,

25005594

ES

Hip fracture, Drug interaction,

DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), LORAZEPAM, VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE, MIRTAZAPINE,

25005618

CA

Back pain, Disturbance in attention, Dizziness, Drug interaction, Fatigue, Headache, Immune-mediated adverse reaction, Irritability, Mental disorder, Muscle twitching, Neuralgia, Off label use, Vascular pain, Vasculitis, Off label use,

HUMAN IMMUNOGLOBULIN G, HUMAN IMMUNOGLOBULIN G, HUMAN IMMUNOGLOBULIN G, HUMAN IMMUNOGLOBULIN G, DALTEPARIN SODIUM, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG,

25005759

FR

Rhabdomyolysis, Drug interaction,

PALBOCICLIB,

25005764

ES

Septic shock, Drug interaction,

EVEROLIMUS, EVEROLIMUS TABLETS, PREDNISONE,

25005914

DE

Hyponatraemia, Delusion, Hallucination, Polydipsia, Paranoia, Delirium, Blood creatine phosphokinase increased, Drug interaction, Overdose, Drug ineffective,

CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, RISPERIDONE, RISPERIDONE, RISPERIDONE, RISPERIDONE, RISPERIDONE,

25005919

CH

Irregular breathing, Drug interaction, Miosis, Consciousness fluctuating,

FENTANYL, FENTANYL, FENTANYL,

25006263

US

Drug interaction, Anxiety, Nausea,

FLUOXETINE HYDROCHLORIDE, SODIUM OXYBATE, SODIUM OXYBATE,