Drug Search by Year (Detail)

25049353

US

Toxicity to various agents, Status epilepticus, Hypotension, Incorrect route of product administration, Wrong product administered,

TRANEXAMIC ACID,

25049509

US

Respiratory distress, Hypotension,

ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, EPINEPHRINE, ADRENALINUM, MONTELUKAST, OMALIZUMAB,

25049556

CA

Anaemia, Arthralgia, Cardiac failure, Fatigue, Feeling cold, Gait disturbance, Hypotension, Inflammation, Injection site nodule, Injection site pain, Injection site swelling, Joint swelling, Movement disorder, Pain, Pain in extremity, Pelvic pain, Peripheral swelling, Pleurisy, Product use in unapproved indication, Pulmonary oedema, Sitting disability, Dyspnoea, Diarrhoea, Hypertension, Infection, Alopecia, Therapeutic response decreased,

LEFLUNOMIDE, SARILUMAB, SARILUMAB, AMLODIPINE, DEXLANSOPRAZOLE, METHOTREXATE, METHOTREXATE SODIUM, PREDNISONE, CONJUGATED ESTROGENS, ESTROGENS, CONJUGATED, LEVOTHYROXINE SODIUM,

25049788

IT

Hyperpyrexia, Hypotension, Drug eruption, Oxygen saturation decreased,

IMATINIB, ALLOPURINOL,

25049993

Hypotension, Atrial fibrillation, Blood pressure orthostatic, Fatigue, Presyncope,

FLUOROURACIL, IRINOTECAN HYDROCHLORIDE, LEUCOVORIN CALCIUM,

25050084

IT

Erythema, Dizziness, Hypotension, Oxygen saturation decreased, Abdominal pain, Retching, Defaecation urgency,

PACLITAXEL,

25050266

DE

Hypotension, Gastrointestinal anastomotic leak, Diarrhoea, Pancytopenia, Off label use,

PEMBROLIZUMAB, PEMBROLIZUMAB, PEMBROLIZUMAB, OXALIPLATIN, OXALIPLATIN, TRASTUZUMAB, TRASTUZUMAB, FLUOROURACIL, FLUOROURACIL, DOCETAXEL, DOCETAXEL ANHYDROUS, DOCETAXEL, DOCETAXEL ANHYDROUS,

25050428

US

Hypotension, Electrocardiogram QT prolonged, Drug interaction,

LISINOPRIL, AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, TIZANIDINE, TIZANIDINE, METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, DOXYCYCLINE, DOXYCYCLINE HYCLATE,

25050781

FR

Hyperthermia, Multiple organ dysfunction syndrome, Disseminated intravascular coagulation, Shock, Metabolic acidosis, Rhabdomyolysis, Renal failure, Hyperkalaemia, Hyperferritinaemia, Mydriasis, Hypotension, White blood cell disorder, Thrombocytopenia, Hyperglycaemia, Loss of consciousness, Leukocytosis, Hepatic cytolysis,

HALOPERIDOL, HALOPERIDOL LACTATE,

25051077

GB

Heart rate increased, Hypotension, Productive cough, Dyspnoea, Lower respiratory tract infection, Arthralgia, Drug ineffective, Musculoskeletal stiffness, Headache, Nasopharyngitis, Cough, Pyrexia, Chest discomfort,

SECUKINUMAB, SECUKINUMAB, METHOTREXATE, METHOTREXATE SODIUM,

25051126

CA

Adverse reaction, Anaphylactic reaction, Anaphylactic shock, Angiopathy, Back pain, Blood pressure increased, Emphysema, Epistaxis, Face oedema, Flatulence, Haemorrhage, Haemothorax, Hypersensitivity, Hypotension, Hypovolaemia, Inspiratory capacity decreased, Mechanical ventilation complication, Pleural effusion, Pneumothorax, Shock haemorrhagic, Tachycardia, Urticaria,

ALBUMIN HUMAN, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, BUDESONIDE, CALCIUM CHLORIDE INJECTION, CALCIUM CHLORIDE, CEFAZOLIN SODIUM, CHLORHEXIDINE GLUCONATE, ANTISEPTIC SKIN CLEANSER, DESMOPRESSIN ACETATE, DIPHENHYDRAMINE, DIPHENHYDRAMINE HYDROCHLORIDE, FAMOTIDINE, GABAPENTIN, HYDROCORTISONE SODIUM SUCCINATE, KETAMINE HYDROCHLORIDE, MORPHINE, NAPROXEN, NOREPINEPHRINE (BITARTRATE), NOREPINEPHRINE BITARTRATE, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, PROPOFOL, ROCURONIUM, ROCURONIUM BROMIDE, SUFENTANIL CITRATE, TRANEXAMIC ACID, VANCOMYCIN HYDROCHLORIDE, ALBUTEROL SULFATE, SUFENTANIL,

25051274

US

Loss of consciousness, Fall, Hypotension, Heart rate decreased, Cardiac disorder, Contusion,

ACALABRUTINIB, ALLOPURINOL, APIXABAN, FUROSEMIDE, LIDOCAINE, LIDOCAINE HYDROCHLORIDE, BURN RELIEF, MAXIMUM STRENGTH PAIN RELIEVER, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE, LIDOCAINE 4%, LIDOCAINE, MENTHOL, MIRABEGRON, PROCHLORPERAZINE, ERGOCALCIFEROL, TIOTROPIUM BROMIDE AND OLODATEROL, BUMETANIDE,

25051431

AU

Flatulence, Renal impairment, Mouth haemorrhage, Fluid retention, Lethargy, Haemorrhoids, Rash pruritic, Heart rate decreased, Diarrhoea, Headache, Dry mouth, Dyspnoea exertional, Pneumonia, Loss of personal independence in daily activities, Diarrhoea, Hypotension, Epistaxis, Heart rate increased,

ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, SELEXIPAG, SELEXIPAG, SELEXIPAG, SELEXIPAG, SELEXIPAG, PANTOPRAZOLE SODIUM, PANTOPRAZOLE, PANTOPRAZOLE SODIUM IN 0.9% SODIUM CHLORIDE, PANTOPRAZOLE SODIUM INJECTION, EPOPROSTENOL, EPOPROSTENOL, EPOPROSTENOL SODIUM, EPOPROSTENOL SODIUM, DOCUSATE SODIUM, DOCUSATE SODIUM 100MG, FUROSEMIDE, FUROSEMIDE, HEPARIN SODIUM, NEBIVOLOL, NEBIVOLOL HYDROCHLORIDE, MACITENTAN, ROSUVASTATIN CALCIUM, SODIUM BICARBONATE, SODIUM BICARBONATE INJECTION,, PANTOPRAZOLE SODIUM, PANTOPRAZOLE, PANTOPRAZOLE SODIUM IN 0.9% SODIUM CHLORIDE, PANTOPRAZOLE SODIUM INJECTION, TADALAFIL,

25051502

FR

Poisoning deliberate, Coma, Hypotension, Sinus bradycardia,

LOXAPINE, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), PROPRANOLOL HYDROCHLORIDE, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL,

25051637

Supraventricular tachycardia, Hypotension, Erythema, Nausea, Vomiting, Abdominal pain, Left ventricular dysfunction,

CEFTRIAXONE, CEFTRIAXONE SODIUM,

25051773

US

Flushing, Headache, Dizziness, Hypotension, Myalgia, Incorrect product administration duration,

RIOCIGUAT, AMBRISENTAN, AMBRISENTAN, SELEXIPAG, SELEXIPAG, SELEXIPAG, SELEXIPAG, SELEXIPAG, AMBRISENTAN,

25051776

US

Hypotension, Platelet count decreased,

CILTACABTAGENE AUTOLEUCEL,

25051923

US

Hypotension, Complication associated with device, Product use issue,

NITRIC OXIDE,

25052250

GB

Hypotension, Headache,

TIRZEPATIDE,

25052294

CA

Hypotension, Pruritus, Rash,

MIDAZOLAM, MIDAZOLAM HYDROCHLORIDE, DIPHENHYDRAMINE HYDROCHLORIDE, FENTANYL,

25052335

CA

Anaphylactic shock, Chest pain, Diarrhoea, Heart rate increased, Hypotension, Pyrexia, Rash, Vomiting,

CYTARABINE, FAMOTIDINE, LANSOPRAZOLE, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, PREDNISONE, VINCRISTINE SULFATE,

25052608

US

Fatigue, Product use in unapproved indication, Hypotension, Asthenia,

LISINOPRIL, FUROSEMIDE, SPIRONOLACTONE, CARVEDILOL,

25058103

Hypotension,

UPADACITINIB,

25043431

GB

Pruritus, Pyrexia, Hypotension, Dizziness, Vision blurred, Urticaria, Hypopnoea,

DUPILUMAB,

25043557

US

Burning sensation, Pain in jaw, Hypotension,

TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, DICLOFENAC SODIUM, DICLOFENAC SODIUM TOPICAL, DICLOFENAC SODIUM TOPICAL GEL, 1%, DICLOFENAC, DICLOFENAC SODIUM 1%, TADALAFIL, POTASSIUM CHLORIDE, POTASSIUM CHLORIDE EXTENDED-RELEASE, POTASSIUM CHLORIDE, DEXTROSE MONOHYDRATE, POTASSIUM CHLORIDE ORAL, MACITENTAN, OXYGEN, 0XYGEN, CALCIUM, GABAPENTIN, FUROSEMIDE, BUPROPION HYDROCHLORIDE, ONDANSETRON HYDROCHLORIDE,

25043733

US

Loss of consciousness, Hypotension, Dehydration,

EMPAGLIFLOZIN, HYDROCHLOROTHIAZIDE,

25043735

AU

Hypotension, Syncope,

IRBESARTAN, CYCLOSPORINE, SPIRONOLACTONE, RISEDRONATE SODIUM, ASIAN GINSENG, ALLOPURINOL, ATENOLOL, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, PRAVASTATIN SODIUM, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, SERTRALINE HYDROCHLORIDE,

25043736

AU

Syncope, Hypotension,

IRBESARTAN, SPIRONOLACTONE, CYCLOSPORINE, RISEDRONATE SODIUM, ALLOPURINOL, ATENOLOL, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, PRAVASTATIN SODIUM, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, SERTRALINE HYDROCHLORIDE,

25043934

GB

Cold sweat, Bradycardia, Dizziness, Vision blurred, Hypotension, Nausea, Hypersensitivity,

LETROZOLE, LETROZOLE TABLETS,

25043968

US

Non-cardiogenic pulmonary oedema, Pulmonary alveolar haemorrhage, Hypoxia, Tachypnoea, Intentional overdose, Hypertension, Hypervolaemia, Hypotension, Tachycardia,

AMLODIPINE BESYLATE,

25043969

NP

Non-cardiogenic pulmonary oedema, Respiratory failure, Loss of consciousness, Urinary tract infection, Toxicity to various agents, Intentional overdose, Oliguria, Tachycardia, Hypotension,

AMLODIPINE BESYLATE,

25043971

US

Drug interaction, Electrocardiogram QT prolonged, Hypotension,

TIZANIDINE, TIZANIDINE, AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, LISINOPRIL, LISINOPRIL, HYDROCHLOROTHIAZIDE, HYDRALAZINE HYDROCHLORIDE,

25044055

TR

Anuria, Hypotension, Suicide attempt, Toxicity to various agents, Somnolence, Overdose,

AMLODIPINE,

25044519

US

Mental status changes, Platelet count decreased, Product dose omission issue, Hypotension, Nausea,

REVUMENIB,

25044635

ES

Blindness, Drug hypersensitivity, Urticaria, Hypotension, Nephropathy, Pain, Deafness,

CARBOPLATIN, ETOPOSIDE, CISPLATIN, THIOTEPA, IFOSFAMIDE, CYCLOPHOSPHAMIDE FOR INJECTION, CYCLOPHOSPHAMIDE, CYCLOPHOSPHAMIDE INJECTION, SOLUTION, DOXORUBICIN, TOPOTECAN, TOPOTECAN, TOPOTECAN, SARGRAMOSTIM, MELPHALAN, NAXITAMAB, NAXITAMAB,

25044683

US

Arrhythmia, Hypotension, Sleep apnoea syndrome, Malaise, Rash, Headache, Fatigue,

RELUGOLIX, RELUGOLIX,

25044873

US

Hypotension, Drug interaction,

DOXYCYCLINE, DOXYCYCLINE HYCLATE, METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, LISINOPRIL, TIZANIDINE, TIZANIDINE,

25044944

US

Somnolence, Intentional overdose, Overdose, Hypotension,

AMLODIPINE, TRANEXAMIC ACID, CLONAZEPAM, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, ZOLPIDEM TARTRATE,

25044993

NO

Ill-defined disorder, Cardiac dysfunction, Hypotension,

GANIRELIX ACETATE, MENOTROPINS,

25045458

US

Cardiogenic shock, Hypotension,

DILTIAZEM HYDROCHLORIDE, DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE TABLETS,

25045511

ID

Dyspnoea, Dyspnoea paroxysmal nocturnal, Negative cardiac inotropic effect, Dyspnoea exertional, Orthopnoea, Cardiac failure, Mitral valve incompetence, Tricuspid valve incompetence, Hyperkalaemia, Type 2 diabetes mellitus, Renal impairment, Venous pressure jugular increased, Hepatomegaly, Peripheral coldness, Coronary artery disease, Hypotension,

25045734

FR

COVID-19, Retinal vein occlusion, Rash pustular, Psychiatric decompensation, Cytomegalovirus infection, Campylobacter bacteraemia, Pneumocystis jirovecii pneumonia, Aspergillus infection, Hyperthermia, Hypotension, Asthma, Rash, Eosinophilia, Neutropenia, Dyspnoea,

RITUXIMAB, PREDNISONE,

25045755

US

Circulatory collapse, Hypotension, Heart rate decreased,

IBRUTINIB, IBRUTINIB,

25045858

US

Hypotension, Dizziness, Heart rate decreased,

LECANEMAB, FLUOXETINE HYDROCHLORIDE, FLUOXETINE, DONEPEZIL HYDROCHLORIDE,

25045927

US

Hypotension,

TIRZEPATIDE,

25046068

CO

Death, Mass, Off label use, Hypotension,

IBRUTINIB,

25046081

CA

Chest pain, Headache, Hyperhidrosis, Hypotension, Seizure,

IFOSFAMIDE, NETUPITANT AND PALONOSETRON, FOSNETUPITANT AND PALONOSETRON,

25046248

DE

Anaphylactic shock, Hypotension, Tachycardia, Dyskinesia, Erythema, Body temperature increased, Breath sounds abnormal,

PROPOFOL, PROPOFOL, CEFUROXIME, SUFENTANIL, SUFENTANIL CITRATE,

25046471

HR

Anaphylactic reaction, Hypotension, Pulse abnormal, Oxygen saturation decreased, Pallor, Hyperhidrosis, Loss of consciousness,

OXALIPLATIN, APIXABAN, BISOPROLOL FUMARATE,

25046773

NL

Respiratory failure, Product use in unapproved indication, Maternal exposure during delivery, Hypotension, Dysphagia,

LIDOCAINE HYDROCHLORIDE, LIDOCAINE HYDROCHLORIDE ANHYDROUS,

25047080

CN

Dizziness, Asthenia, Hypotension, Hypoglycaemia,

SODIUM CHLORIDE, SODIUM CHLORIDE INJECTION, SODIUM CHLORIDE TABLET, NORMAL SALT TABLETS,

25047285

US

Drug interaction, Hypotension,

TIZANIDINE, TIZANIDINE, LISINOPRIL, LISINOPRIL, METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, DOXYCYCLINE, DOXYCYCLINE HYCLATE,

25047997

AU

Femoral neck fracture, Device issue, Heart rate decreased, Hypotension,

25038950

GB

Blood calcium decreased, Rash papular, Urinary tract infection, Mobility decreased, Body temperature abnormal, Circulatory collapse, Blood pressure increased, Muscular weakness, Pollakiuria, Hypertension, Blister, Diarrhoea, Treatment delayed, Abdominal pain upper, Fatigue, Injection site mass, Malaise, Illness, Fatigue, Diarrhoea, Diarrhoea, Hypotension, Loss of consciousness, Injection site mass, Chromaturia, Blood potassium decreased, Malaise, Malaise,

LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, CLOPIDOGREL, CLOPIDOGREL BISULFATE,

25039017

US

Pulmonary arterial hypertension, Hypotension,

TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, BOSENTAN,

25039693

US

Pyrexia, Sepsis, Atrial fibrillation, Pulmonary embolism, Deep vein thrombosis, Chronic kidney disease, Renal failure, Disability, Drug hypersensitivity, Musculoskeletal stiffness, Drug intolerance, Gout, Osteoarthritis, Weight increased, Osteopenia, Skin atrophy, Electrocardiogram ST-T segment abnormal, Hypotension, Arthritis, Asthenia, Infusion related reaction, Hypertension, Pain, Glucose-6-phosphate dehydrogenase abnormal, Myalgia, Arthralgia,

METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, FEBUXOSTAT, FEBUXOSTAT, COLCHICINE, PEGLOTICASE, PEGLOTICASE, PEGLOTICASE, PEGLOTICASE, ALLOPURINOL, APIXABAN, ACETAMINOPHEN, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE, ACETAMINOPHEN, GABAPENTIN, CLONIDINE, EMPAGLIFLOZIN, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, METOCLOPRAMIDE HYDROCHLORIDE, NITROGLYCERIN, METOCLOPRAMIDE, METOCLOPRAMIDE HYDROCHLORIDE,

25039914

US

Somnolence, Hypotension, Intentional overdose,

TRANEXAMIC ACID, AMLODIPINE, CLONAZEPAM, ZOLPIDEM TARTRATE, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL,

25039920

US

Status epilepticus, Medication error, Hypotension,

TRANEXAMIC ACID,

25039939

HR

Suicide attempt, Intentional product use issue, Lethargy, Hypotension,

DICLOFENAC, DICLOFENAC SODIUM, ALLOPURINOL, ZOLPIDEM TARTRATE, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, ALPRAZOLAM, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, PANTOPRAZOLE SODIUM, PANTOPRAZOLE, PANTOPRAZOLE SODIUM IN 0.9% SODIUM CHLORIDE, PANTOPRAZOLE SODIUM INJECTION,

25039990

FR

Poisoning deliberate, Coma, Hypotension, Sinus bradycardia,

DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, PROPRANOLOL HYDROCHLORIDE, LOXAPINE,

25040062

US

Gastrointestinal haemorrhage, Hypoxia, Cardiac failure congestive, Hypervolaemia, Chest pain, Hypotension,

AMBRISENTAN, ALLOPURINOL, DOFETILIDE, FLUTICASONE PROPIONATE AND SALMETEROL XINAFOATE, FOLIC ACID, GABAPENTIN, INSULIN ASPART, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, SERTRALINE, SILDENAFIL CITRATE, THIAMINE HYDROCHLORIDE,

25040072

US

Hypotension,

25040095

FR

Hypotension, Electrocardiogram QT prolonged, Malaise,

SERTRALINE, HYDROXYZINE HYDROCHLORIDE, HYDROXYZINE,

25040221

US

Arrhythmia, Hypotension,

PIMAVANSERIN TARTRATE,

25040237

CA

Blood pressure systolic increased, Decreased appetite, Dermatitis atopic, Eczema, Hypotension, Insomnia, Middle insomnia, Product supply issue, Skin plaque, Dizziness, Nausea, Urticaria, Drug ineffective,

OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, CETIRIZINE, CETIRIZINE HYDROCHLORIDE, CETIIRIZINE, DUPILUMAB, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, DESOXIMETASONE,

25040433

FR

Electrocardiogram QT prolonged, Malaise, Hypotension,

SERTRALINE, HYDROXYZINE HYDROCHLORIDE, HYDROXYZINE,

25040472

PT

Tremor, Hypotension, Diarrhoea,

ANASTROZOLE, ANASTROZOLE TABLETS,

25040594

JP

Cardiac failure, Hypotension, Off label use, Dyspnoea, Peripheral coldness, Frequent bowel movements,

MACITENTAN, SELEXIPAG, RIOCIGUAT, WARFARIN, HYDROCORTISONE BUTYRATE,

25041155

TR

Toxicity to various agents, Suicide attempt, Hypotension, Anuria,

AMLODIPINE,

25041167

US

Hypotension, Product administration error, Status epilepticus, Toxicity to various agents,

FOSPHENYTOIN, FOSPHENYTOIN SODIUM, MIDAZOLAM, MIDAZOLAM HYDROCHLORIDE, PROPOFOL, TRANEXAMIC ACID,

25041511

PL

Drug dependence, Neuroglycopenia, Dementia, Sedation, Mobility decreased, Motor dysfunction, Hiatus hernia, Orthostatic hypotension, Pruritus, Hypotension, Hypoglycaemia, Parkinsonism, Syncope, Hyponatraemia, Bradykinesia, Dizziness, Hyperkalaemia, Urinary retention, Osteoporosis, Blood potassium increased, General physical health deterioration, Nausea, Dysuria, Hyperglycaemia, Off label use, Atrial fibrillation, Blood creatine increased, Diabetes mellitus inadequate control, Constipation, Blood cholesterol decreased, Depression, Melaena, Peripheral circulatory failure, Muscle rigidity, Gastrointestinal disorder, Stupor, Blood creatinine increased, Hypotonia, Cognitive disorder, Blood urea increased, Gastric polyps, Arthralgia, Abdominal pain upper, Initial insomnia, Insomnia, Blood pressure decreased, Hypertension, Atrioventricular block first degree, Fall,

ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, ALLOPURINOL, AMLODIPINE BESYLATE, METOCLOPRAMIDE, METOCLOPRAMIDE HYDROCHLORIDE, DEXTROSE MONOHYDRATE, DEXTROSE, LEVOTHYROXINE, TORSEMIDE, ALBUTEROL SULFATE, ALBUTEROL, ALBUTEROL SULFATE, ALBUTEROL, ISOSORBIDE MONONITRATE, HYDROCHLOROTHIAZIDE, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE, METOPROLOL, HYDROXYZINE, VORTIOXETINE, DONEPEZIL HYDROCHLORIDE, DABIGATRAN ETEXILATE, CITALOPRAM, CITALOPRAM HYDROBROMIDE, CITALOPRAM, CITALOPRAM HYDROBROMIDE, SPIRONOLACTONE, HYDROXYZINE, HYDROXYZINE, HYDROXYZINE, POTASSIUM CHLORIDE, POTASSIUM CHLORIDE EXTENDED-RELEASE, POTASSIUM CHLORIDE, DEXTROSE MONOHYDRATE, POTASSIUM CHLORIDE ORAL, ALPRAZOLAM, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, RAMIPRIL, ACARBOSE, ZOLPIDEM TARTRATE, LEVOTHYROXINE SODIUM, LEVOTHYROXINE SODIUM ANHYDROUS, TRAMADOL HYDROCHLORIDE, DABIGATRAN ETEXILATE, ALLOPURINOL, ZOLPIDEM TARTRATE, ZOLPIDEM TARTRATE, ZOLPIDEM TARTRATE, ATORVASTATIN CALCIUM, ATORVASTATIN CALCIUM, FILM COATED, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, LEVOTHYROXINE SODIUM, LEVOTHYROXINE SODIUM ANHYDROUS, DENOSUMAB, TRAMADOL HYDROCHLORIDE, POTASSIUM CHLORIDE, POTASSIUM CHLORIDE EXTENDED-RELEASE, POTASSIUM CHLORIDE, DEXTROSE MONOHYDRATE, POTASSIUM CHLORIDE ORAL, ISOSORBIDE MONONITRATE, HYDROXYZINE, HYDROXYZINE, RAMIPRIL,

25041568

CA

Hypertension, Movement disorder, Infection, Product use in unapproved indication, Arthralgia, Dyspnoea, Cardiac failure, Injection site nodule, Inflammation, Hypotension, Pulmonary oedema, Sitting disability, Fatigue, Pain in extremity, Peripheral swelling, Pain, Joint swelling, Gait disturbance, Pelvic pain, Pleurisy, Injection site swelling, Diarrhoea, Therapeutic response decreased, Injection site pain, Alopecia, Anaemia, Feeling cold,

LEFLUNOMIDE, METHOTREXATE, METHOTREXATE SODIUM, DEXLANSOPRAZOLE, AMLODIPINE, SARILUMAB, SARILUMAB, ERGOCALCIFEROL, PREDNISONE, CONJUGATED ESTROGENS, ESTROGENS, CONJUGATED, LEVOTHYROXINE SODIUM,

25041609

FR

Coma, Hypotension, Poisoning deliberate, Sinus bradycardia,

DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), PROPRANOLOL HYDROCHLORIDE, LOXAPINE, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL,

25041634

CA

Hypotension, Infusion related reaction, Loss of consciousness, Oxygen saturation decreased,

ETOPOSIDE, NETUPITANT AND PALONOSETRON, FOSNETUPITANT AND PALONOSETRON, DEXAMETHASONE, DEXAMETHASONE 1.5 MG, OLANZAPINE, PEGFILGRASTIM, PROCHLORPERAZINE,

25042033

GB

Blood calcium decreased, Blood potassium decreased, Loss of consciousness, Circulatory collapse, Urinary tract infection, Pollakiuria, Chromaturia, Malaise, Body temperature abnormal, Illness, Mobility decreased, Blood pressure increased, Muscular weakness, Hypotension, Blister, Hypertension, Rash papular, Fatigue, Fatigue, Abdominal pain upper, Injection site mass, Injection site mass, Diarrhoea, Diarrhoea, Diarrhoea, Treatment delayed, Malaise,

LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, CLOPIDOGREL, CLOPIDOGREL BISULFATE,

25042752

CA

Acute kidney injury, Asthenia, Cardiac failure, Dizziness, Fall, Hypotension,

SPIRONOLACTONE, BISOPROLOL FUMARATE, SACUBITRIL AND VALSARTAN, FUROSEMIDE,

25042938

CA

Hypotension,

REMDESIVIR,

25043095

US

Full blood count decreased, Lethargy, Hypotension,

UPADACITINIB,

25043199

CA

Gastrointestinal disorder, Transaminases increased, Acute kidney injury, Blood bilirubin increased, Hypotension, Blood creatine phosphokinase increased, Hepatobiliary disease,

25034058

US

Hypotension, Dizziness,

TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, MELATONIN, TAMSULOSIN HYDROCHLORIDE, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, APIXABAN, ACETAMINOPHEN, DIPHENHYDRAMINE HYDROCHLORIDE, ACETAMINOPHEN AND DIPHENHYDRAMINE HYDROCHLORIDE, UMECLIDINIUM, POTASSIUM CHLORIDE, METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, OXYGEN, 0XYGEN, LEVOTHYROXINE SODIUM, LEVOTHYROXINE SODIUM ANHYDROUS,

25034343

US

Transplantation complication, Death, Acute lymphocytic leukaemia recurrent, Neutropenia, Sepsis, Febrile neutropenia, Bacteraemia, Pneumonia, Urinary tract infection, Pneumonia, Diarrhoea, Colitis, Infection, Hyperglycaemia, Hypocalcaemia, Hypotension, Thrombocytopenia,

PEGFILGRASTIM, PREDNISONE, BLINATUMOMAB, RITUXIMAB, VENETOCLAX,

25034629

SA

Hypotension,

SOMATROPIN, HYDROCORTISONE, ANTIPRURITIC (ANTI-ITCH), ANTI-ITCH CREAM, HYDROCORTISONE 1%, HYDROCORTISONE CONTINUOUS SPRAY, ANTI-PRURITIC, HYDROCORTISONE LOTION, HYDROCORTISONE ACETATE, HYDROCORTISONE LOTION KIT, ANTI ITCH, ANTI-ITCH, COOL RELIEF GEL WITH ALOE, HYDROCORTISONE CREAM 1%, HYDROCORTISONE SPRAY, DRS. HYDROCORTISONE, LEVOTHYROXINE,

25034855

US

Drug interaction, Hypotension,

LISINOPRIL, TIZANIDINE,

25034918

PT

Cardiac arrest, Hypotension, Sinus bradycardia, Drug ineffective,

TELMISARTAN, SUGAMMADEX, FENTANYL, PROPOFOL, SEVOFLURANE, CEFAZOLIN SODIUM, CEFAZOLIN, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, ROCURONIUM, ROCURONIUM BROMIDE,

25035033

US

Hypotension, Drug interaction,

LISINOPRIL, TIZANIDINE, TIZANIDINE, METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, DOXYCYCLINE, DOXYCYCLINE HYCLATE,

25035034

US

Bradycardia, Hypotension, Drug interaction,

LISINOPRIL, TIZANIDINE, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, CHLORPROMAZINE, CITALOPRAM, CITALOPRAM HYDROBROMIDE, FINASTERIDE, LIDOCAINE PATCH, LIDOCAINE 4%, MENTHOL 1%, LIDOCAINE, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, PRAMIPEXOLE, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, SIMVASTATIN, THEOPHYLLINE, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS,

25035155

US

Toxicity to various agents, Exposure during pregnancy, Drug interaction, Hypotension, Live birth, Malaise, Chest discomfort, Hypertension, Pre-eclampsia, Abdominal pain upper,

FENTANYL, MAGNESIUM SULFATE, MAGNESIUM SULFATE HEPTAHYDRATE, MAGNESIUM SULFATE IN WATER FOR, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, NICARDIPINE, LABETALOL, AZATHIOPRINE, DARUNAVIR, DARUNAVIR 600 MG, DARUNAVIR 800 MG, RIFAMPIN, RITONAVIR, RITONAVIR 100 MG,

25035323

HU

Hypotension, Metastases to lymph nodes, Circulatory collapse,

PERTUZUMAB, TRASTUZUMAB, AND HYALURONIDASE-ZZXF, PERTUZUMAB, TRASTUZUMAB, AND HYALURONIDASE-ZZXF,

25035382

PR

Hypotension, Abdominal pain upper, Illness,

LENALIDOMIDE, TIOTROPIUM BROMIDE, SIMVASTATIN, ALENDRONATE SODIUM, ALENDRONATE SODIUM TABLET, LISINOPRIL,

25035660

CA

Abdominal pain, Asthenia, Blister, Blood creatine phosphokinase increased, Blood iron decreased, Blood magnesium decreased, Blood pressure decreased, Blood pressure decreased, Blood pressure diastolic decreased, Blood pressure systolic decreased, Blood pressure systolic decreased, Blood pressure systolic decreased, Blood test abnormal, Breast disorder, Constipation, Constipation, Dry mouth, Dry skin, Dry throat, Dysmenorrhoea, Eczema, Electric shock sensation, Epistaxis, Epistaxis, Faeces soft, Fatigue, Fatigue, Fatigue, Gingival pain, Headache, Headache, Headache, Heart rate decreased, Hepatitis, Hyperaesthesia, Hyperaesthesia, Hyperaesthesia, Hypotension, Hypotension, Injection site haemorrhage, Malaise, Malignant neoplasm progression, Muscular weakness, Myalgia, Nasopharyngitis, Nausea, Nausea, Pain, Palpitations, Paraesthesia, Pruritus, Recurrent cancer, Seasonal allergy, Skin fissures, Sneezing, Stress, Tumour marker increased, Urinary tract infection, Vulvovaginal pain, Weight decreased, Weight decreased, Weight increased,

HUMAN IMMUNOGLOBULIN G, ADO-TRASTUZUMAB EMTANSINE, ADO-TRASTUZUMAB EMTANSINE, ADO-TRASTUZUMAB EMTANSINE, ADO-TRASTUZUMAB EMTANSINE, PERTUZUMAB, PERTUZUMAB, PERTUZUMAB, CAPECITABINE, TRASTUZUMAB, TRASTUZUMAB, TRASTUZUMAB, TRASTUZUMAB, TRASTUZUMAB, TRASTUZUMAB, TRASTUZUMAB, TRASTUZUMAB, TRASTUZUMAB, DIPHENHYDRAMINE HYDROCHLORIDE, HEPARIN SODIUM AND DEXTROSE, HEPARIN SODIUM, MAGNESIUM, PACLITAXEL, METHYLPREDNISOLONE SODIUM SUCCINATE, TRAMADOL HYDROCHLORIDE, TRASTUZUMAB-QYYP, TRAMADOL HYDROCHLORIDE,

25035686

US

Electrocardiogram QT prolonged, Hypotension, Drug interaction,

LISINOPRIL, TIZANIDINE HYDROCHLORIDE, TIZANIDINE HYDROCHLORIDE, AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, METOPROLOL TARTRATE, METOPROLOL, DOXYCYCLINE, DOXYCYCLINE HYCLATE,

25035811

CA

Vomiting, Anal incontinence, Back pain, Chest discomfort, Chills, Dyspnoea, Hypertension, Hypotension, Pyrexia, Tachycardia,

HUMAN IMMUNOGLOBULIN G, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, ATOVAQUONE, CYCLOPHOSPHAMIDE FOR INJECTION, CYCLOPHOSPHAMIDE, CYCLOPHOSPHAMIDE INJECTION, SOLUTION, DIPHENHYDRAMINE, DIPHENHYDRAMINE HYDROCHLORIDE, FAMOTIDINE, FLUCONAZOLE, HYDROCORTISONE, ANTIPRURITIC (ANTI-ITCH), ANTI-ITCH CREAM, HYDROCORTISONE 1%, HYDROCORTISONE CONTINUOUS SPRAY, ANTI-PRURITIC, HYDROCORTISONE LOTION, HYDROCORTISONE ACETATE, HYDROCORTISONE LOTION KIT, ANTI ITCH, ANTI-ITCH, COOL RELIEF GEL WITH ALOE, HYDROCORTISONE CREAM 1%, HYDROCORTISONE SPRAY, DRS. HYDROCORTISONE, VALACYCLOVIR HYDROCHLORIDE, VALACYCLOVIR,

25035838

Wound, Acute kidney injury, Tachycardia, Hypotension,

FLUOROURACIL, LEUCOVORIN CALCIUM, NIVOLUMAB,

25035898

FR

Rash, Hypotension, Tachycardia, Respiratory disorder,

ATROPINE SULFATE, ATROPINE SULFATE MONOHYDRATE, ATROPINE SULFATE INJECTION, SUFENTANIL, POVIDONE-IODINE, POVIDONE IODINE, 10% POVIDONE-IODINE, OXYTOCIN, CEFAZOLIN SODIUM, CEFAZOLIN,

25036080

PT

Chest pain, Dyspnoea, Hypotension,

AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, LEVOTHYROXINE SODIUM, LEVOTHYROXINE SODIUM ANHYDROUS,

25036105

IN

Death, Hypotension, Pulmonary oedema,

DURVALUMAB,

25036211

US

Hypotension,

PIMAVANSERIN TARTRATE, CARBIDOPA AND LEVODOPA,

25036226

US

Septic shock, Lactic acidosis, Hypotension, Drug ineffective,

HYDROCORTISONE, ANTIPRURITIC (ANTI-ITCH), ANTI-ITCH CREAM, HYDROCORTISONE 1%, HYDROCORTISONE CONTINUOUS SPRAY, ANTI-PRURITIC, HYDROCORTISONE LOTION, HYDROCORTISONE ACETATE, HYDROCORTISONE LOTION KIT, ANTI ITCH, ANTI-ITCH, COOL RELIEF GEL WITH ALOE, HYDROCORTISONE CREAM 1%, HYDROCORTISONE SPRAY, DRS. HYDROCORTISONE, VANCOMYCIN HYDROCHLORIDE, VANCOMYCIN, CEFEPIME HYDROCHLORIDE, CEFEPIME, ACYCLOVIR,

25036307

NL

Respiratory failure, Hypotension, Dysphagia, Maternal exposure during delivery, Product use in unapproved indication,

LIDOCAINE, LIDOCAINE HYDROCHLORIDE, BURN RELIEF, MAXIMUM STRENGTH PAIN RELIEVER, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE, LIDOCAINE 4%, LIDOCAINE, MENTHOL,

25036400

ES

Blindness, Deafness, Nephropathy, Pain, Urticaria, Hypotension,

DOXORUBICIN, IFOSFAMIDE, ETOPOSIDE, THIOTEPA, NAXITAMAB, SARGRAMOSTIM,