Drug Search by Year (Detail)

26940105

EU

Septic shock, Drug tolerance decreased, Anaemia, Infection, Therapeutic product effect incomplete, Vena cava thrombosis,

VENETOCLAX,

26940149

US

Anaemia, Fatigue,

ROPEGINTERFERON ALFA-2B,

26940568

CA

Unevaluable event, Anaemia,

GLYCEROL PHENYLBUTYRATE,

26940694

EU

Diabetic ketoacidosis, Neutropenia, Anaemia, Cytomegalovirus colitis,

TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, VALGANCICLOVIR HYDROCHLORIDE, VALGANCICLOVIR, VALGANCICLOVIR HYDROCHLORIDE POWDER,,

26940707

EU

Bronchitis, Pneumonia, Arrhythmia, Anaemia,

GUSELKUMAB, GUSELKUMAB, GUSELKUMAB, GUSELKUMAB, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, ORAL SEMAGLUTIDE, DABIGATRAN ETEXILATE MESYLATE, DABIGATRAN ETEXILATE, BISOPROLOL FUMARATE,

26940742

Diabetic ketoacidosis, Neutropenia, Anaemia, Cytomegalovirus colitis, Drug ineffective, Off label use,

PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, VALGANCICLOVIR HYDROCHLORIDE, VALGANCICLOVIR,

26940880

EU

Anaemia, Leukopenia, Neutropenia, Anaemia, Leukopenia, Neutropenia, Thrombocytopenia, Anaemia, Leukopenia, Neutropenia, Pancytopenia, Anaemia, Weight decreased,

RIBOCICLIB, RIBOCICLIB, RIBOCICLIB, RIBOCICLIB, RIBOCICLIB,

26941049

EU

Gastric ulcer, Anaemia,

ZANUBRUTINIB, ZANUBRUTINIB, EDOXABAN TOSYLATE,

26941359

EU

Haematotoxicity, Anaemia, Nausea,

BEVACIZUMAB, OLAPARIB,

26941524

KH

Cholelithiasis, Chronic myeloid leukaemia, Malignant neoplasm progression, Vaginal haemorrhage, Uterine haemorrhage, Haematochezia, Hypothyroidism, Malaise, Diabetes mellitus, Loose tooth, Blood creatinine decreased, Varicose vein, Drug intolerance, Cardiac disorder, Crying, Transferrin saturation decreased, Blood cholesterol increased, Microalbuminuria, White blood cell count increased, Prothrombin time shortened, Blood lactate dehydrogenase abnormal, Lymphocyte count abnormal, Antinuclear antibody positive, Blood triglycerides increased, Product dose omission issue, Iron deficiency anaemia, Alanine aminotransferase abnormal, Aspartate aminotransferase abnormal, Manganese increased, Neutrophil count increased, Mean cell haemoglobin concentration abnormal, Neck pain, Back pain, Pallor, Ocular hyperaemia, Pain, Peripheral swelling, Oedema peripheral, Normochromic normocytic anaemia, Hepatomegaly, Dyslipidaemia, Hyperglycaemia, Hepatic steatosis, Arthralgia, Pain in extremity, Chest pain, Haemoglobin decreased, Anaemia, Dyspnoea, Anxiety, Tachycardia, White blood cell count abnormal, Cough, Blood pressure increased, Blood iron decreased, Cytogenetic analysis abnormal, Hypertension, Depression,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, NILOTINIB, DICLOFENAC, DICLOFENAC SODIUM, DIPHENHYDRAMINE, DIPHENHYDRAMINE HYDROCHLORIDE, MAGNESIUM SULFATE, MAGNESIUM SULFATE HEPTAHYDRATE, MAGNESIUM SULFATE IN WATER FOR, CALCIUM,

26941836

US

Thrombocytopenia, Anaemia, Neutropenia, Hypertension, Fatigue, Nausea, Myelodysplastic syndrome, Renal failure,

BEVACIZUMAB, OLAPARIB, NIRAPARIB, RUCAPARIB,

26942491

US

Urinary tract infection, Upper respiratory tract infection, Headache, Arthralgia, Pyrexia, Protein urine present, Inflammatory marker increased, Blood immunoglobulin G increased, Blood immunoglobulin E increased, Serum ferritin increased, Anaemia,

HUMAN IMMUNOGLOBULIN G, HUMAN IMMUNOGLOBULIN G, VEDOLIZUMAB,

26942582

Kaposi^s sarcoma, Anaemia, Aplasia pure red cell, Off label use,

TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, METHYLPREDNISOLONE,

26942587

Kaposi^s sarcoma, Anaemia, Cytomegalovirus colitis, Off label use,

TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION,

26943088

EU

Anaemia, Eastern Cooperative Oncology Group performance status worsened,

ENZALUTAMIDE, LUTETIUM LU 177 VIPIVOTIDE TETRAXETAN, PREGABALIN, DENOSUMAB, CALCIUM CARBONATE, ANTACID, PREDNISONE, FILGRASTIM,

26943192

Anaemia,

DARATUMUMAB, DOXORUBICIN HYDROCHLORIDE, DOXORUBICIN, ETOPOSIDE, VINCRISTINE SULFATE,

26943194

EU

Faecaloma, Balance disorder, Brain fog, Malaise, Dizziness, Alopecia, Anaemia, Enteritis, Gastrointestinal inflammation, White blood cell count decreased,

FULVESTRANT, FULVESTRANT, ABEMACICLIB,

26943232

Anaemia,

DARATUMUMAB, DOXORUBICIN HYDROCHLORIDE, DOXORUBICIN, ETOPOSIDE, VINCRISTINE SULFATE,

26943235

Bradycardia, Hypotension, Pyrexia, Lung infiltration, Respiratory failure, Shock, Pulmonary embolism, Dyspnoea, Syncope, Anaemia, Asthenia, Cardio-respiratory arrest, Aspiration,

DOXORUBICIN HYDROCHLORIDE, DOXORUBICIN,

26943305

US

Pain, Weight decreased, Diarrhoea, Anaemia, Condition aggravated, Infection,

SARILUMAB,

26943603

EU

Anaemia, Granulocytopenia,

ZOLPIDEM TARTRATE, AMLODIPINE, VINORELBINE, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, SIMVASTATIN, IRON, PREDNISONE,

26943707

EU

Clostridium difficile colitis, Dyspnoea, Pain, Condition aggravated, Inflammatory marker increased, Anaemia, Oedema peripheral, Pleural effusion, Respiratory failure, Serratia infection, General physical health deterioration, Swelling, Clostridium difficile infection, Laboratory test abnormal, Drug ineffective,

PANTOPRAZOLE, CLOPIDOGREL, CLOPIDOGREL BISULFATE, METRONIDAZOLE, METRONIDAZOLE TOPICAL, PREGABALIN, PREGABALIN, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, BISOPROLOL FUMARATE, BISOPROLOL FUMARATE, BISOPROLOL FUMARATE, RAMIPRIL, PIPERACILLIN SODIUM,TAZOBACTAM SODIUM, CYCLOSPORINE, CALCIUM, PREDNISONE, PREDNISONE, PREDNISONE, PREDNISONE, CALCIUM GLUCONATE, IRON SUCROSE, TORSEMIDE, ERYTHROPOIETIN, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, FUROSEMIDE, FUROSEMIDE, FUROSEMIDE,

26943865

US

Blood urea increased, Blood creatinine increased, Glomerular filtration rate decreased, Creatinine renal clearance decreased, Blood bicarbonate decreased, Protein total decreased, Anaemia, Fatigue,

SPARSENTAN, SPARSENTAN, SPARSENTAN, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE,

26943995

EU

Cardiac arrest, Dysphonia, Poisoning, Coagulopathy, Anaemia, Full blood count abnormal, Abdominal distension, Hepatic failure,

EPINEPHRINE, ADRENALINUM, EPINEPHRINE, ADRENALINUM, EPINEPHRINE, ADRENALINUM, EPINEPHRINE, ADRENALINUM, MIDAZOLAM HYDROCHLORIDE, MIDAZOLAM HYDROCHLORIDE, MIDAZOLAM HYDROCHLORIDE, MIDAZOLAM HYDROCHLORIDE, TRANEXAMIC ACID, TRANEXAMIC ACID, TRANEXAMIC ACID, TRANEXAMIC ACID,

26944333

GB

Respiratory failure, Acute kidney injury, Electrocardiogram QT prolonged, Electrocardiogram PR prolongation, Atrioventricular block, Differential white blood cell count abnormal, Anaemia,

CLOZAPINE,

26944542

Drug ineffective, Anaemia, Hypotension,

SPARSENTAN,

26944658

CA

Blood pressure abnormal, Varices oesophageal, Blood creatinine increased, Cystitis, Nausea, Vomiting, Dehydration, Anaemia, Alanine aminotransferase decreased,

ELAFIBRANOR, DAPAGLIFLOZIN, ORAL SEMAGLUTIDE, CARVEDILOL,

26944839

Anaemia, Haematuria,

RIVAROXABAN,

26945148

EU

Anaemia, Pulseless electrical activity, Overdose,

METHYLENE BLUE, EPINEPHRINE,

26945267

EU

Anaemia, Lower gastrointestinal haemorrhage, Product prescribing error,

RIVAROXABAN, APIXABAN,

26945440

EU

Anaemia, Lower gastrointestinal haemorrhage, Product prescribing error,

RIVAROXABAN, RIVAROXABAN, APIXABAN,

26945701

JP

Anaemia, Haematochezia, Diverticulum intestinal haemorrhagic, Portal vein thrombosis, Haemobilia,

PACLITAXEL, PACLITAXEL, GEMCITABINE HYDROCHLORIDE, GEMCITABINE HYDROCHLORIDE, LANSOPRAZOLE, OXYCODONE HYDROCHLORIDE, OXYCODONE,

26945760

GB

Anaemia,

CLOZAPINE,

26945837

US

Weight increased, Anaemia, Abdominal distension, Rash, Bone pain,

ABALOPARATIDE, IRON,

26945942

US

Urine abnormality, Fatigue, Anaemia,

SPARSENTAN, PANTOPRAZOLE, ROSUVASTATIN, FLUOXETINE HYDROCHLORIDE, CETIRIZINE HYDROCHLORIDE, CETIRIZINE, CETIRIZINE HYDROCHLORIDE ALLERGY, CETIRIZINE HYDROCHLORIDE TABLETS,

26946596

US

Anaemia,

ABALOPARATIDE,

26947271

US

Anaemia,

ABALOPARATIDE, ABALOPARATIDE, AMLODIPINE, AMOXICILLIN, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, CARVEDILOL, IRON,

26947639

US

Anaemia, Off label use,

RUXOLITINIB, ROMIPLOSTIM, ERYTHROPOIETIN,

26947643

US

Anaemia, Platelet count decreased, Off label use,

RUXOLITINIB, TOFACITINIB, TOFACITINIB CITRATE,

26947718

US

Influenza, Anaemia, Vitamin D increased, Injection site erythema, Injection site bruising, Injection site pain, Blood calcium increased,

ABALOPARATIDE, OLOPATADINE HYDROCHLORIDE, AZELAIC ACID, 12%AZELAIC ACID, 14%AZELAIC ACID, BUDESONIDE, CALCIUM, BIOTIN, MAGNESIUM, CETIRIZINE HCL, CETIRIZINE, ERGOCALCIFEROL,

26934094

CA

Arthritis, Hypoaesthesia, Oxygen saturation decreased, Product use issue, Thermal burn, Weight decreased, Body temperature decreased, Insomnia, Weight increased, Dry eye, Micturition disorder, Oedema peripheral, Ligament rupture, Blood pressure increased, Nerve compression, Gingival ulceration, Musculoskeletal stiffness, Blood pressure fluctuation, Pain in extremity, Joint range of motion decreased, Arthralgia, Blood pressure decreased, Mass, Infusion related reaction, Rash, Skin abrasion, Peripheral swelling, Pain, Dysuria, Paraesthesia, Skin papilloma, Blood pressure diastolic decreased, Dry skin, Neck pain, Skin discolouration, Blood pressure systolic increased, Cystitis bacterial, Blood pressure diastolic abnormal, Inflammation, Mouth ulceration, Fall, Anaemia, Rib fracture, Drug ineffective, Musculoskeletal stiffness, Back pain, Ill-defined disorder, Blood pressure systolic abnormal, Heart rate decreased, Pruritus, Osteoarthritis, Dry throat, Arthralgia, Arthralgia, Arthralgia, Pain,

METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, CELECOXIB, ACETAMINOPHEN, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE, ACETAMINOPHEN, FOLIC ACID,

26934238

Bronchiectasis, Atelectasis, Anaemia, Infection protozoal, Pneumonia, Off label use,

METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION,

26935017

US

Atrial fibrillation, White blood cell count decreased, Platelet count decreased, Anaemia, Myalgia, Bone pain, Arthralgia, Rash, Stomatitis, Blood creatinine increased,

OSIMERTINIB,

26935026

CN

Anaemia, Pneumonia, Hypokalaemia, Arrhythmia, Hypokalaemia, Hypokalaemia, Deep vein thrombosis, Ascites, Anaemia, Hypocalcaemia, Anaemia, Anaemia, Weight decreased, Anaemia, Hypocalcaemia, Decreased appetite, Hypocalcaemia, Hypocalcaemia, Supraventricular tachycardia, Anaemia, Platelet count decreased, Hypocalcaemia, White blood cell count decreased, Hypocalcaemia, Neutrophil count decreased, Anaemia, Decreased appetite, Sinus tachycardia, Anaemia, Pyrexia, Hypocalcaemia, Insomnia, Hypocalcaemia, Platelet count decreased, Hypoproteinaemia, Infection, Anaemia, Hypocalcaemia, Platelet count decreased, White blood cell count decreased, Anaemia, Hypocalcaemia, Platelet count decreased, Hypocalcaemia, Hypersensitivity, Anaemia, Anaemia, Hypocalcaemia, Constipation, Anaemia, Platelet count decreased, Hypocalcaemia, Oedema peripheral, Platelet count decreased, Nausea, Vomiting, Anaemia, Hypocalcaemia, Platelet count decreased, Constipation, Hypocalcaemia, Pelvic fluid collection, Diarrhoea, Dysuria, Hypocalcaemia,

SOTORASIB, SOTORASIB,

26935134

US

Anaemia, Lymphocyte count decreased,

TEMOZOLOMIDE, AMLODIPINE BESYLATE, ATORVASTATIN CALCIUM, OLMESARTAN MEDOXOMIL-HYDROCHLOROTHIAZIDE, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, ACETAMINOPHEN AND CODEINE, STANDARDIZED SENNA CONCENTRATE AND DOCUSATE SODIUM, SODIUM CHLORIDE, SODIUM CHLORIDE TABLET, SODIUM CHLORIDE TABLETS, LEVETIRACETAM,

26935349

EU

Contusion, Mouth haemorrhage, Subcutaneous haematoma, Anaemia, International normalised ratio increased, Off label use,

ENOXAPARIN SODIUM, ENOXAPARIN SODIUM, CHLORHEXIDINE GLUCONATE, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, TIOTROPIUM BROMIDE, BISOPROLOL FUMARATE, FUROSEMIDE, PANTOPRAZOLE, SPIRONOLACTONE, URSODIOL, URSOSIOL,

26935797

CN

Upper gastrointestinal haemorrhage, Conjunctival pallor, Diverticulum intestinal, Palpitations, Atrioventricular block, Dry mouth, Listless, Nausea, Faeces soft, Intestinal obstruction, Neuropathy peripheral, Discomfort, Throat lesion, Haematemesis, Asthenia, Gastric ulcer, Gastric ulcer haemorrhage, Dizziness, Hyperhidrosis, Deep vein thrombosis, Arrhythmia, Renal impairment, Pyrexia, Pain, Decreased appetite, Anaemia, Abdominal tenderness, Fatigue, Gastric haemorrhage,

DICLOFENAC SODIUM, DICLOFENAC SODIUM TOPICAL, DICLOFENAC SODIUM TOPICAL GEL, 1%, DICLOFENAC, DICLOFENAC SODIUM 1%,

26936055

US

Ulcer haemorrhage, Anaemia, Arthritis, Vision blurred, Bone density decreased, Heart rate irregular, Headache, Mobility decreased, Myalgia, Bacterial test positive, High density lipoprotein decreased, Blood calcium decreased, Blood creatinine increased,

DENOSUMAB, AMLODIPINE, CETIRIZINE, CETIRIZINE HYDROCHLORIDE, CETIIRIZINE, CHLORHEXIDINE GLUCONATE, DOCUSATE SODIUM, DOCUSATE SODIUM 100MG, ESOMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM, ESOMEPRAZOLE MAGNESIUM CAPSULE, DELAYED RELEASE, ESOMEPRAZOLE MAGNESIUM DIHYDRATE, ESOMEPRAZOLE MAGNESIUM DELAYED RELEASE CAPSULES, FLUTICASONE PROPIONATE, FLUTICASONE PROPIONATE NASAL, LIDOCAINE, LIDOCAINE HYDROCHLORIDE, BURN RELIEF, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE, LIDICAINE, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE, LIDOCAINE 4%, LIDOCAINE, MENTHOL, LIDOCAINE, LIDOCAINE HYDROCHLORIDE, BURN RELIEF, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE, LIDICAINE, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE, LIDOCAINE 4%, LIDOCAINE, MENTHOL, LIDOCAINE, LIDOCAINE HYDROCHLORIDE, BURN RELIEF, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE, LIDICAINE, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE, LIDOCAINE 4%, LIDOCAINE, MENTHOL, MAGNESIUM, TELMISARTAN,

26936154

JP

Malignant neoplasm progression, Anaemia, Malaise,

BELZUTIFAN,

26936169

EU

Anaemia, Off label use,

LUTETIUM LU 177 VIPIVOTIDE TETRAXETAN, LUTETIUM LU 177 VIPIVOTIDE TETRAXETAN, LUTETIUM LU 177 VIPIVOTIDE TETRAXETAN,

26936194

CN

Neutropenia, Thrombocytopenia, Anaemia, Hypoalbuminaemia, Hypokalaemia, Infection, Hypoalbuminaemia, Alanine aminotransferase increased, Aspartate aminotransferase increased, Blood bilirubin increased,

RITUXIMAB, LENALIDOMIDE, ZANUBRUTINIB,

26936382

Anaemia, Overdose,

METHYLENE BLUE, METHYLENE BLUE, METHYLENE BLUE, EPINEPHRINE, ADRENALINUM, SODIUM NITRITE,

26936505

Gastrointestinal haemorrhage, Melaena, Anaemia,

APIXABAN, APIXABAN,

26936515

EU

Accidental overdose, Thrombocytopenia, Anaemia, Neutropenia, Mucosal inflammation, Rash,

METHOTREXATE SODIUM, PREDNISONE, FOLIC ACID, ESCITALOPRAM OXALATE, ESCITALOPRAM,

26936904

US

Small intestinal obstruction, Prostate cancer, Anaemia, Abdominal adhesions, Blood iron decreased, Blood phosphorus decreased, Product dose omission issue,

RUXOLITINIB,

26936955

IR

Infection protozoal, Bronchiectasis, Atelectasis, Pneumonia, Anaemia,

METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION,

26937355

GB

Anaemia,

CLOZAPINE,

26937462

US

Full blood count decreased, Anaemia, Decreased appetite, Insomnia, Wrong technique in product usage process,

RUXOLITINIB, RUXOLITINIB, RUXOLITINIB,

26937563

US

Lymphopenia, Hypoalbuminaemia, Anaemia, Diarrhoea, Hepatic failure, Haemorrhage, Embolism, Liver function test abnormal,

BEVACIZUMAB, ATEZOLIZUMAB,

26938105

CN

Leukopenia, Neutropenia, Thrombocytopenia, Anaemia, Decreased appetite, Fatigue, Hypertension, Palmar-plantar erythrodysaesthesia syndrome, Proteinuria, Neuropathy peripheral, Transaminases increased, Mouth ulceration, Stomatitis, Abdominal pain, Diarrhoea, Hyperbilirubinaemia, Blood lactate dehydrogenase increased, Blood alkaline phosphatase increased, Gamma-glutamyltransferase increased, Hypoproteinaemia, Dysphagia, Dysphonia, Hypothyroidism, Hyperthyroidism, Rash, Hepatitis, Pruritus, Pneumonia, Infusion related reaction, Nephritis,

ATEZOLIZUMAB, PEMBROLIZUMAB, PACLITAXEL, PACLITAXEL (AIBUMIN-BOUND), NIVOLUMAB,

26938450

EU

Oedema peripheral, Blood pressure increased, Hypotension, Constipation, Haemorrhage, Anaemia, Blood fibrinogen decreased,

DEXMEDETOMIDINE, ALBUTEROL SULFATE, ALBUTEROL, MIDAZOLAM, MIDAZOLAM HYDROCHLORIDE, TRANEXAMIC ACID, CAPTOPRIL,

26938859

US

Anaemia,

POMALIDOMIDE, POMALIDOMIDE,

26939153

US

Hypoacusis, Anaemia,

ABALOPARATIDE,

26939309

US

Febrile neutropenia, Tumour lysis syndrome, Neutropenia, Differentiation syndrome, Thrombocytopenia, Sepsis, Electrocardiogram QT prolonged, Anaemia, Blood disorder, Infection, Pneumonia,

IVOSIDENIB, AZACITIDINE, AZACITIDINE FOR,

26939325

US

Haemorrhage, Malignant neoplasm progression, Anaemia, Thrombocytopenia,

IVOSIDENIB, IVOSIDENIB, AZACITIDINE, AZACITIDINE FOR, AZACITIDINE, AZACITIDINE FOR,

26939800

JP

Anaemia, Hypoxia,

BELZUTIFAN, LEVOTHYROXINE SODIUM, LEVOTHYROXINE SODIUM ANHYDROUS, AMLODIPINE, SACUBITRIL AND VALSARTAN, CARVEDILOL,

26943525

Anaemia,

ALECTINIB HYDROCHLORIDE,

26931321

CN

Hepatic function abnormal, Pneumonia, Aortic valve incompetence, Tricuspid valve incompetence, Hepatic function abnormal, Mycoplasma infection, Hyperthyroidism, Hepatic function abnormal, Hepatic cyst, Anaemia, Chest discomfort, Hypoalbuminaemia, Blood glucose increased, Rash, Hyponatraemia, Hepatic function abnormal, Hypoalbuminaemia, Hepatic function abnormal, Hypoalbuminaemia, Hepatic function abnormal, Hypoalbuminaemia, Hyperuricaemia, Uterine leiomyoma, Neutrophil count decreased, Neutrophil count decreased, Hepatic function abnormal, Anaemia, Hepatic function abnormal,

SOTORASIB,

26931612

CN

Hepatic function abnormal, Jaundice, Respiratory failure, Altered state of consciousness, Acidosis, Hepatic function abnormal, Jaundice, Urinary tract infection, Pain in extremity, Anaemia, Urinary tract infection, Constipation, Urinary tract infection, Hypoalbuminaemia,

SOTORASIB,

26931667

EU

Septic shock, Off label use, Metabolic disorder, Fatigue, Mental disorder, Atrial fibrillation, Injury, Neutropenia, Urinary tract infection, Angiopathy, COVID-19, Benign neoplasm, Infusion related reaction, Renal disorder, COVID-19 pneumonia, Dyspnoea, Poisoning, Procedural complication, Nausea, Vision blurred, Neoplasm malignant, Neoplasm, Dry eye, Anaemia, Oedema peripheral, Arthralgia, Skin disorder, Hypertension, Cyst, Urinary tract disorder, Eye irritation, Pneumonia, Malnutrition, Diarrhoea, Cough, Infestation, Polyp, General symptom, Cardiac disorder, Spinal disorder, Investigation abnormal, Gastrointestinal disorder, Nervous system disorder, Respiratory disorder, Musculoskeletal disorder, Adverse event, Lymphatic disorder, Eye disorder, Administration site reaction, Mediastinal disorder, Blood disorder, Infection, Connective tissue disorder,

IBRUTINIB, RITUXIMAB,

26931937

EU

Thrombocytopenia, Asthenia, Anaemia,

PEMBROLIZUMAB, CARBOPLATIN, FLUOROURACIL CREAM, 0.5%, FLUOROURACIL,

26932271

MK

Thrombocytopenia, Nephropathy toxic, Immune-mediated hypothyroidism, Anaemia,

DURVALUMAB, CISPLATIN, GEMCITABINE HYDROCHLORIDE, GEMCITABINE,

26932360

EU

Head and neck cancer, Anaemia, Product ineffective for unapproved use, Product use in unapproved indication, Drug ineffective,

PREGABALIN, PREGABALIN,

26932566

EU

Heavy menstrual bleeding, Anaemia,

RIVAROXABAN, RIVAROXABAN, CLOPIDOGREL, CLOPIDOGREL BISULFATE, APIXABAN,

26933079

CA

Malignant neoplasm progression, Fall, Contusion, Asthenia, Hospitalisation, Muscular weakness, Hypertension, Blood potassium decreased, Angioplasty, Malignant neoplasm progression, Gastric cancer, Headache, Migraine, Myalgia, Abdominal pain, Flatulence, Faeces discoloured, Nausea, Alopecia, Decreased appetite, Weight decreased, Breast discolouration, Insomnia, Pain in extremity, Off label use, Arthralgia, Diarrhoea, Abdominal pain upper, Off label use, Sinusitis, Eye infection, Anaemia, Pancreatic disorder, Vomiting, Nausea, Faeces discoloured, Abdominal pain upper, Polyp, Urinary tract infection, Fatigue, Diarrhoea, Abdominal distension, Stomach mass, Abdominal pain, Nausea, Vomiting, Diarrhoea, Fatigue, Polyp, Diarrhoea, Haemorrhoidal haemorrhage, Pain, Loss of personal independence in daily activities, Conjunctival laceration, Fall, Joint injury, Skin abrasion, Contusion, Pain, Fatigue, Pain, Nausea, Vomiting, Diarrhoea, Fall, Limb injury, Eye irritation, Walking aid user, Entropion, Asthenia, Fatigue,

LANREOTIDE ACETATE, LANREOTIDE ACETATE, LANREOTIDE ACETATE, LANREOTIDE ACETATE, LANSOPRAZOLE, CLONAZEPAM, ACETAMINOPHEN, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE, ACETAMINOPHEN, CHOLESTYRAMINE,

26933880

CN

Cardiac failure, Neuropathy peripheral, Pyrexia, Dyspnoea, Headache, Anaemia, Neutrophil count decreased, Platelet count decreased, Hypertension, Infection, Off label use, Tumour marker decreased,

DARATUMUMAB, DARATUMUMAB,

26933952

JP

Febrile neutropenia, Neutrophil count decreased, White blood cell count decreased, Anaemia, Platelet count decreased, Incorrect drug administration rate,

TRABECTEDIN, TRABECTEDIN, DOXORUBICIN HYDROCHLORIDE, DOXORUBICIN, DOXORUBICIN HYDROCHLORIDE, DOXORUBICIN,

26926691

US

Seizure, Blood sodium decreased, Headache, Platelet count increased, Laboratory test abnormal, Anaemia,

IBRUTINIB, IBRUTINIB, ALLOPURINOL, BUPROPION, FUROSEMIDE,

26926693

CN

Immune-mediated lung disease, Pneumonia fungal, Respiratory failure, Malignant neoplasm progression, Anaemia, Cardio-respiratory arrest,

NIVOLUMAB, NIVOLUMAB, CISPLATIN, FLUOROURACIL CREAM, 0.5%, FLUOROURACIL,

26927154

EU

Anaemia, Asthenia, Thrombocytopenia,

FLUOROURACIL CREAM, 0.5%, FLUOROURACIL, PEMBROLIZUMAB, CARBOPLATIN,

26927174

CN

Platelet count decreased, Platelet count decreased, Anaemia, Platelet count decreased, Anaemia,

SOTORASIB,

26927317

US

Knee arthroplasty, Tricuspid valve incompetence, Carotid artery occlusion, Left ventricular failure, Hypothyroidism, Dementia Alzheimer^s type, Mitral valve incompetence, Arteriosclerosis coronary artery, Type IIa hyperlipidaemia, Carotid artery stenosis, Type 2 diabetes mellitus, Fall, Hip arthroplasty, Alcohol abuse, Aortic valve stenosis, Essential hypertension, Back pain, Anaemia of chronic disease, Muscular weakness, Cough, Rhinitis allergic, Vitamin D deficiency, Nicotine dependence, Anaemia, Lumbosacral plexopathy, Peripheral vascular disorder, Constipation, Intervertebral disc degeneration, Cardiomegaly, Physical examination abnormal, Respiratory disorder, Vitamin B complex deficiency, Osteoarthritis, Cardiovascular symptom, Arthralgia,

DENOSUMAB, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, CELECOXIB, ATORVASTATIN CALCIUM, ERGOCALCIFEROL,

26927330

US

Syncope, Blindness transient, Dyspnoea, Anaemia, Fatigue, Nausea, Therapy interrupted, Blood creatinine increased, Glomerular filtration rate decreased, Product dose omission in error,

OLAPARIB, OLAPARIB, OLAPARIB,

26927373

US

Gastrointestinal toxicity, Abdominal discomfort, Nausea, Diarrhoea, Anaemia, Fatigue, Blood iron decreased,

CYCLOPHOSPHAMIDE FOR INJECTION, CYCLOPHOSPHAMIDE, CYCLOPHOSPHAMIDE INJECTION, SOLUTION, CYCLOPHOSPHAMIDE FOR INJECTION, CYCLOPHOSPHAMIDE, CYCLOPHOSPHAMIDE INJECTION, SOLUTION, DOCETAXEL, DOCETAXEL ANHYDROUS, DOCETAXEL, DOCETAXEL ANHYDROUS, PEGFILGRASTIM,

26927374

JP

Anaemia, Dizziness, Nausea, Oesophageal haemorrhage, Discoloured vomit,

ENTACAPONE, ENTACAPONE, SELEGILINE HYDROCHLORIDE, ZONISAMIDE, ROTIGOTINE, MAGNESIUM OXIDE,

26927539

CN

Neutropenia, Febrile neutropenia, Anaemia, Thrombocytopenia, Pneumonia, Sepsis, Bacteraemia, Cardiac failure, Arrhythmia, Mucosal inflammation, Diarrhoea, Peripheral sensorimotor neuropathy, Fatigue, Asthenia, Death,

RITUXIMAB, CYCLOPHOSPHAMIDE FOR INJECTION, CYCLOPHOSPHAMIDE, CYCLOPHOSPHAMIDE INJECTION, SOLUTION, DOXORUBICIN, PREDNISONE,

26927710

GB

Diverticulitis, Anaemia, Rheumatoid arthritis,

UPADACITINIB,

26927784

VN

Diarrhoea, Nausea, Fatigue, Vomiting, Alanine aminotransferase increased, Aspartate aminotransferase increased, Myalgia, Arthralgia, Anaemia, Rash,

CERITINIB, CERITINIB,

26928647

JP

Anaemia, Platelet count decreased, Off label use,

MACITENTAN, SELEXIPAG,

26928855

EU

Shock haemorrhagic, Anaemia, Melaena,

RIVAROXABAN,

26929033

CN

Neutrophil count decreased, White blood cell count decreased, Anaemia, Platelet count decreased, Lymphocyte count decreased, Alanine aminotransferase increased, Nausea, Vomiting, Constipation, Asthenia, Diarrhoea, Pruritus, Aspartate aminotransferase increased, Electrocardiogram QT prolonged, Decreased appetite,

TRASTUZUMAB, TRASTUZUMAB, PERTUZUMAB, CARBOPLATIN, DOXORUBICIN, PACLITAXEL, PACLITAXEL (AIBUMIN-BOUND), CYCLOPHOSPHAMIDE FOR INJECTION, CYCLOPHOSPHAMIDE, CYCLOPHOSPHAMIDE INJECTION, SOLUTION,

26929067

JP

Traumatic intracranial haemorrhage, Deep dissecting haematoma, Shock, Cardio-respiratory arrest, Fall, Anaemia, Skin necrosis, Haematoma infection,

PRASUGREL HYDROCHLORIDE,

26929114

KR

Platelet count decreased, White blood cell count decreased, Anaemia, Neutrophil count decreased,

NIRAPARIB, DESVENLAFAXINE SUCCINATE, AMISULPRIDE, ZOLPIDEM TARTRATE,

26929630

EU

General physical health deterioration, Clostridium difficile infection, Laboratory test abnormal, Drug ineffective, Clostridium difficile colitis, Dyspnoea, Pain, Condition aggravated, Inflammatory marker increased, Anaemia, Oedema peripheral, Pleural effusion, Respiratory failure, Serratia infection,

PREGABALIN, PREGABALIN, RAMIPRIL, PANTOPRAZOLE, CLOPIDOGREL, CLOPIDOGREL BISULFATE, BISOPROLOL FUMARATE, BISOPROLOL FUMARATE, BISOPROLOL FUMARATE, TORSEMIDE, METRONIDAZOLE, METRONIDAZOLE TOPICAL, PREDNISONE, PREDNISONE, PREDNISONE, PREDNISONE, PIPERACILLIN SODIUM AND TAZOBACTAM SODIUM, PIPERACILLIN AND TAZOBACTAM, PIPERACILLIN SODIUM,TAZOBACTAM SODIUM, CYCLOSPORINE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, CALCIUM, CALCIUM GLUCONATE, IRON SUCROSE, ERGOCALCIFEROL, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, FUROSEMIDE, FUROSEMIDE, FUROSEMIDE, FUROSEMIDE, ERYTHROPOIETIN,

26930123

EU

Eructation, Pulmonary hypertension, Hiatus hernia, Inflammatory marker increased, Hepatic cyst, Gait disturbance, Coronary artery disease, Decreased appetite, Urinary tract infection, Acute kidney injury, Aplastic anaemia, Urinary retention, Wound dehiscence, Arterial haemorrhage, Diverticulum intestinal, Pancreatic steatosis, Myocardial infarction, Haemarthrosis, Tricuspid valve incompetence, Myelodysplastic syndrome, Impaired healing, General physical health deterioration, Cardiogenic shock, Faecaloma, Left ventricular dysfunction, Abdominal discomfort, Arthralgia, Femoral hernia incarcerated, Fall, Mitral valve incompetence, Dyspnoea, Wound infection pseudomonas, Postoperative wound infection, Escherichia infection, Joint dislocation, Aortic valve stenosis, Cardiovascular disorder, Anaemia, Gastrointestinal haemorrhage, Lymphatic fistula, Seroma, Groin pain,

CANDESARTAN CILEXETIL AND HYDROCHLOROTHIAZIDE, PANTOPRAZOLE, PANTOPRAZOLE, EDOXABAN TOSYLATE, EDOXABAN TOSYLATE, BISOPROLOL FUMARATE, BISOPROLOL FUMARATE, SIMVASTATIN, TORSEMIDE, TORSEMIDE, CLOPIDOGREL BISULFATE, AMIODARONE HYDROCHLORIDE, METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, ADALIMUMAB, ADALIMUMAB, ADALIMUMAB, ADALIMUMAB, ADALIMUMAB, ADALIMUMAB, ADALIMUMAB, ADALIMUMAB, ADALIMUMAB, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, VALSARTAN, VALSARTAN ORAL, DICLOFENAC SODIUM, DICLOFENAC SODIUM TOPICAL, DICLOFENAC SODIUM TOPICAL GEL, 1%, DICLOFENAC, DICLOFENAC SODIUM 1%, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, FENTANYL, ESOMEPRAZOLE, ESOMEPRAZOLE, TORSEMIDE, TORSEMIDE, SODIUM CHLORIDE, SODIUM CHLORIDE TABLET, SODIUM CHLORIDE TABLETS, SODIUM CHLORIDE, SODIUM CHLORIDE TABLET, SODIUM CHLORIDE TABLETS, FOLIC ACID, LACTULOSE, TROSPIUM CHLORIDE, TROSPIUM CHLORIDE,

26930499

CN

Pneumonia, Liver injury, Hypokalaemia, Hypokalaemia, Aortic arteriosclerosis, Hyperadrenocorticism, Pneumonia, Pneumonia, Hyperkalaemia, Pneumonia, Pneumonia, Pneumonia, Pneumonia, Diarrhoea, Drug eruption, Infection, Diarrhoea, Nausea, Platelet count increased, Hypoproteinaemia, Dyspepsia, Renal cyst, Anaemia, Oedema peripheral, Infection, Diarrhoea, Hypocalcaemia, Diarrhoea, Hyperparathyroidism, Proteinuria, Malnutrition, Anaemia, Anaemia, Anaemia, Fatigue,

SOTORASIB,

26930888

EU

Major depression, Hepatic cytolysis, Neutropenia, Anaemia,

ZOLEDRONIC ACID, PALBOCICLIB, PALBOCICLIB, LETROZOLE, LETROZOLE TABLETS,

26930980

EU

Pseudomonas infection, Bronchitis, Anaemia, Hypokalaemia, Gastroenteritis cryptosporidial, Sepsis syndrome, Joint effusion, Pleural effusion,

DARATUMUMAB, DARATUMUMAB, DARATUMUMAB, DARATUMUMAB,

26921385

US

Illness, Anaemia,

TIRZEPATIDE,

26921440

US

White blood cell count increased, Anaemia,

ESOMEPRAZOLE MAGNESIUM,