Drug:
Reaction: CONDITION AGGRAVATED
20250101 - 20251231
No. 1 - 100
| No. | safetyreportid |
occurcountry |
patientonsetage |
patientsex 1:M 2:F |
|---|---|---|---|---|
Adverse reaction |
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Drug (openfda.generic_name, medicinalproduct) |
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| 1 | 25491667 |
US |
46 | 1 |
Nasal congestion, Condition aggravated, Hypersensitivity, |
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DUPILUMAB, |
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| 2 | 25491696 |
US |
81 | 2 |
Nasal congestion, Nasal obstruction, Sinus congestion, Condition aggravated, |
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DUPILUMAB, |
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| 3 | 25491767 |
US |
49 | 2 |
Pain, Feeling abnormal, Condition aggravated, Hypokinesia, Gait inability, Speech disorder, Dyspnoea, Stress, Conversion disorder, Feeling drunk, |
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OFATUMUMAB, MORPHINE, PREDNISONE, |
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| 4 | 25491775 |
US |
2 | |
Product dose omission issue, Adverse event, Condition aggravated, |
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MACITENTAN, |
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| 5 | 25491802 |
CA |
40 | 2 |
Blepharospasm, Abdominal discomfort, Abdominal pain upper, Alopecia, Anti-cyclic citrullinated peptide antibody positive, Arthralgia, Asthenia, C-reactive protein abnormal, Condition aggravated, Diarrhoea, Drug hypersensitivity, Obesity, Pain in extremity, Peripheral venous disease, Sleep disorder, Synovitis, Dry mouth, Exposure during pregnancy, Finger deformity, Gait inability, Gastrointestinal disorder, Grip strength decreased, Headache, Hepatic enzyme increased, Hypercholesterolaemia, Hypersensitivity, Impaired healing, Infusion related reaction, Insomnia, Joint swelling, Lung disorder, Muscle injury, Musculoskeletal pain, Musculoskeletal stiffness, Nail disorder, Neck pain, Night sweats, |
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DICLOFENAC, DICLOFENAC SODIUM, DICLOFENAC SODIUM, DICLOFENAC SODIUM, ATOMOXETINE, ATOMOXETINE, ATOMOXETINE, SECUKINUMAB, OXYCODONE, HYDROXYCHLOROQUINE SULFATE, PREDNISONE, PREDNISONE, PREDNISONE, PREDNISONE, PREDNISONE, RANITIDINE, ERENUMAB-AOOE, ERENUMAB-AOOE, ERENUMAB-AOOE, ERENUMAB-AOOE, CAFFEINE, CAFFEINE, CAFFEINE, CAFFEINE, CAFFEINE, CANDESARTAN, LEFLUNOMIDE, LEFLUNOMIDE, PSEUDOEPHEDRINE HYDROCHLORIDE, PSEUDOEPHEDRINE HCL, RAMIPRIL, RAMIPRIL, INFLIXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, SULFASALAZINE, GOLIMUMAB, GOLIMUMAB, GOLIMUMAB, GOLIMUMAB, GOLIMUMAB, SULFASALAZINE, SULFASALAZINE, SULFASALAZINE, SULFASALAZINE, SULFASALAZINE, TRAMADOL HYDROCHLORIDE, TOFACITINIB, TOFACITINIB, |
||||
| 6 | 25491818 |
US |
16 | 1 |
Burning sensation, Condition aggravated, Injection site pain, Rash, |
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DUPILUMAB, |
||||
| 7 | 25491856 |
US |
2 | |
Psoriatic arthropathy, Condition aggravated, Hidradenitis, |
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BIMEKIZUMAB, BIMEKIZUMAB, |
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| 8 | 25491905 |
US |
49 | 1 |
Eczema nummular, Condition aggravated, |
||||
DUPILUMAB, |
||||
| 9 | 25491978 |
US |
||
Erythema, Condition aggravated, Rash, Product use in unapproved indication, |
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CALCIPOTRIENE, |
||||
| 10 | 25492059 |
CA |
||
Renal impairment, Condition aggravated, C-reactive protein increased, Flatulence, Anaemia, Pyrexia, Fatigue, Intentional product use issue, |
||||
INFLIXIMAB, |
||||
| 11 | 25492132 |
US |
44 | 1 |
Endotracheal intubation, Somnolence, Condition aggravated, Restlessness, Condition aggravated, Agitation, Condition aggravated, Yawning, Condition aggravated, Piloerection, Condition aggravated, |
||||
DROPERIDOL, FENTANYL, MIDAZOLAM, MIDAZOLAM HYDROCHLORIDE, MIDAZOLAM, MIDAZOLAM HYDROCHLORIDE, NALOXONE, |
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| 12 | 25492160 |
US |
23 | 1 |
Condition aggravated, Disturbance in social behaviour, Agitation, Off label use, Off label use, |
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PALIPERIDONE PALMITATE, PALIPERIDONE PALMITATE, PALIPERIDONE PALMITATE, |
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| 13 | 25492355 |
US |
86 | 2 |
BRASH syndrome, Condition aggravated, |
||||
METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, APIXABAN, HYDRALAZINE HYDROCHLORIDE, ISOSORBIDE DINITRATE, LEVOTHYROXINE, |
||||
| 14 | 25492356 |
US |
80 | 1 |
Withdrawal syndrome, Condition aggravated, Nausea, Vomiting, Diarrhoea, |
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BUPRENORPHINE, BUPRENORPHINE, LORAZEPAM, METHADONE, NALOXONE, OXYCODONE, |
||||
| 15 | 25492448 |
US |
53 | 1 |
Piloerection, Agitation, Hyperhidrosis, Condition aggravated, |
||||
BUPRENORPHINE AND NALOXONE, BUPRENORPHINE HYDROCHLORIDE AND NALOXONE HYDROCHLORIDE, DEXMEDETOMIDINE, |
||||
| 16 | 25492479 |
FR |
18 | 1 |
Drug level above therapeutic, Gamma-glutamyltransferase increased, Condition aggravated, |
||||
LEVOTHYROXINE SODIUM, LEVOTHYROXINE SODIUM ANHYDROUS, METHYLPREDNISOLONE, ISAVUCONAZONIUM SULFATE, FOLIC ACID, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, RUXOLITINIB, SERTRALINE HYDROCHLORIDE, PIPERACILLIN SODIUM AND TAZOBACTAM SODIUM, PIPERACILLIN AND TAZOBACTAM, PIPERACILLIN SODIUM,TAZOBACTAM SODIUM, NALBUPHINE HYDROCHLORIDE, AMLODIPINE, AZITHROMYCIN DIHYDRATE, |
||||
| 17 | 25492738 |
AU |
65 | 1 |
Drug ineffective for unapproved indication, Condition aggravated, |
||||
GANCICLOVIR SODIUM, GANCICLOVIR, METHYLPREDNISOLONE, ALBUMIN HUMAN, |
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| 18 | 25492773 |
CA |
2 | |
Confusional state, Arthropathy, Asthenia, Asthma, Autoimmune disorder, Back injury, Blepharospasm, Blister, Blood cholesterol increased, Bone erosion, Breast cancer stage II, Breast cancer stage III, Bursitis, C-reactive protein increased, Chest pain, Condition aggravated, |
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ALENDRONATE SODIUM, ALENDRONATE SODIUM, ALENDRONATE SODIUM, ALENDRONATE SODIUM, ACETAMINOPHEN AND CODEINE, ACETAMINOPHEN AND CODEINE, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, ADALIMUMAB, ADALIMUMAB-FKJP, ADALIMUMAB-AATY, ADALIMUMAB, ADALIMUMAB-FKJP, ADALIMUMAB-AATY, PREDNISONE, PREDNISONE, PREDNISONE, DICLOFENAC POTASSIUM, DICLOFENAC POTASSIUM, FILM COATED, DICLOFENAC POTASSIUM TABLETS, APREMILAST, LEFLUNOMIDE, LEFLUNOMIDE, LEFLUNOMIDE, LEFLUNOMIDE, LEFLUNOMIDE, LEFLUNOMIDE, LEFLUNOMIDE, LEFLUNOMIDE, ATOMOXETINE HYDROCHLORIDE, ATOMOXETINE HYDROCHLORIDE, BOTULINUM TOXIN TYPE A, BUPRENORPHINE, BUPRENORPHINE, CALCIUM GLUCONATE, CALCIUM GLUCONATE, CANDESARTAN, CELECOXIB, CERTOLIZUMAB PEGOL, CERTOLIZUMAB PEGOL, SECUKINUMAB, DICLOFENAC POTASSIUM, DICLOFENAC POTASSIUM, FILM COATED, DICLOFENAC POTASSIUM TABLETS, DICLOFENAC SODIUM, DICLOFENAC SODIUM TOPICAL, DICLOFENAC SODIUM TOPICAL GEL, 1%, DICLOFENAC, DICLOFENAC SODIUM 1%, DICLOFENAC SODIUM, DICLOFENAC SODIUM TOPICAL, DICLOFENAC SODIUM TOPICAL GEL, 1%, DICLOFENAC, DICLOFENAC SODIUM 1%, ETANERCEPT, ERENUMAB-AOOE, INFLIXIMAB, LEFLUNOMIDE, METHOTREXATE SODIUM, METHOTREXATE SODIUM, METHOTREXATE SODIUM, METHOTREXATE SODIUM, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE, OXYCODONE, PANTOPRAZOLE, PHENYLEPHRINE HYDROCHLORIDE, RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, SULFASALAZINE, SULFASALAZINE, SULFASALAZINE, SULFASALAZINE, SULFASALAZINE, SULFASALAZINE, SULFASALAZINE, SULFASALAZINE, SULFASALAZINE, TOFACITINIB, ADALIMUMAB, ADALIMUMAB-FKJP, ADALIMUMAB-AATY, DICLOFENAC POTASSIUM, DICLOFENAC POTASSIUM, FILM COATED, DICLOFENAC POTASSIUM TABLETS, BOTULINUM TOXIN TYPE A, BUPRENORPHINE, CELECOXIB, LEFLUNOMIDE, LEFLUNOMIDE, LEFLUNOMIDE, LEFLUNOMIDE, |
||||
| 19 | 25492774 |
US |
44 | 2 |
Vomiting, Diarrhoea, Withdrawal syndrome, Delirium, Condition aggravated, |
||||
DROPERIDOL, NALOXONE, BUPRENORPHINE, DEXMEDETOMIDINE, |
||||
| 20 | 25492786 |
US |
1 | |
Hallucinations, mixed, Condition aggravated, Product dose omission issue, |
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PIMAVANSERIN TARTRATE, PIMAVANSERIN TARTRATE, |
||||
| 21 | 25492808 |
US |
86 | 2 |
BRASH syndrome, Condition aggravated, |
||||
METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, APIXABAN, ISOSORBIDE DINITRATE, HYDRALAZINE HYDROCHLORIDE, LEVOTHYROXINE, |
||||
| 22 | 25492846 |
US |
72 | 1 |
Condition aggravated, Rash, Pruritus, Feeling hot, |
||||
CARVEDILOL, DULOXETINE HYDROCHLORIDE, DULOXETIN HYDROCHLORIDE, DULOXETINE, SACUBITRIL AND VALSARTAN, EZETIMIBE, FUROSEMIDE, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, PROPAFENONE, ROSUVASTATIN, SPIRONOLACTONE, |
||||
| 23 | 25493081 |
US |
69 | 2 |
Mycobacterium avium complex infection, Condition aggravated, Drug resistance, Product use in unapproved indication, |
||||
RIFAMPIN, RIFAMPIN, AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, AMIKACIN, |
||||
| 24 | 25493371 |
US |
82 | 1 |
Hemiparesis, Condition aggravated, Diarrhoea, Fatigue, Vomiting, Dyspnoea, |
||||
ABALOPARATIDE, ABALOPARATIDE, |
||||
| 25 | 25493408 |
BY |
42 | 1 |
Condition aggravated, |
||||
VANCOMYCIN HYDROCHLORIDE, VANCOMYCIN, VANCOMYCIN HYDROCHLORIDE, VANCOMYCIN, VANCOMYCIN HYDROCHLORIDE, VANCOMYCIN, VANCOMYCIN HYDROCHLORIDE, VANCOMYCIN, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE, METOPROLOL, SPIRONOLACTONE, SPIRONOLACTONE, SPIRONOLACTONE, SPIRONOLACTONE, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, FUROSEMIDE, FUROSEMIDE, FUROSEMIDE, FUROSEMIDE, EFAVIRENZ, EFAVIRENZ, EFAVIRENZ, EFAVIRENZ, |
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| 26 | 25493449 |
CA |
2 | |
Colitis ulcerative, Condition aggravated, Dyspepsia, Decreased appetite, Face injury, Gastritis, Scar, Gastric haemorrhage, Acne, Alopecia, Drug ineffective, |
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ISOTRETINOIN, ISOTRETINOIN, ISOTRETINOIN, ISOTRETINOIN, ISOTRETINOIN, ISOTRETINOIN, ISOTRETINOIN, ISOTRETINOIN, |
||||
| 27 | 25493626 |
CH |
||
Hallucination, Condition aggravated, Impulse-control disorder, Stress, Panic attack, |
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LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE, LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE, BRIVARACETAM, PERAMPANEL, PERAMPANEL, ZONISAMIDE, ZONISAMIDE, TOPIRAMATE, TOPIRAMATE SPINKLE, TOPIRAMATE, TOPIRAMATE SPINKLE, LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, VALPROIC ACID, |
||||
| 28 | 25493653 |
IN |
5 | 2 |
Condition aggravated, |
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CARBOPLATIN, PACLITAXEL, |
||||
| 29 | 25493712 |
US |
2 | |
Rebound effect, Uveitis, Choroiditis, Condition aggravated, Off label use, |
||||
MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, |
||||
| 30 | 25493783 |
US |
||
Condition aggravated, Therapy partial responder, |
||||
ALBUTEROL SULFATE, |
||||
| 31 | 25493791 |
IT |
59 | 2 |
Toxic skin eruption, Condition aggravated, |
||||
| 32 | 25493889 |
US |
56 | 2 |
Arthralgia, Hot flush, Condition aggravated, Drug ineffective, Product substitution issue, |
||||
ESTRADIOL, PROGESTERONE, |
||||
| 33 | 25493977 |
CA |
50 | 1 |
Condition aggravated, Removal of internal fixation, |
||||
METHOTREXATE SODIUM, NIFEDIPINE, PREDNISONE, |
||||
| 34 | 25494024 |
DE |
62 | 1 |
Terminal ileitis, Spinal disorder, Back disorder, Musculoskeletal disorder, Abdominal pain, Diarrhoea, Arthropathy, Condition aggravated, Arthropathy, |
||||
ADALIMUMAB, ADALIMUMAB-FKJP, ADALIMUMAB-AATY, SECUKINUMAB, PREDNISONE, METHOTREXATE SODIUM, |
||||
| 35 | 25494096 |
ES |
48 | 1 |
Acute kidney injury, Condition aggravated, |
||||
IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE, |
||||
| 36 | 25494148 |
US |
2 | |
Loss of consciousness, Polyarthritis, Ankylosing spondylitis, Von Willebrand^s disease, Intervertebral disc displacement, Pain, Fatigue, Emotional disorder, Cervicogenic headache, Spondyloarthropathy, Abdominal pain upper, White blood cell count decreased, Essential hypertension, Migraine, Anxiety disorder, Ehlers-Danlos syndrome, Concussion, Raynaud^s phenomenon, Anaemia, Abdominal pain, Gastrooesophageal reflux disease, Rhinitis allergic, Affective disorder, Sleep apnoea syndrome, Essential tremor, Behaviour disorder, Condition aggravated, Gastritis, Neck pain, Acute sinusitis, Conjunctivitis allergic, Inappropriate schedule of product administration, |
||||
DUPILUMAB, ADALIMUMAB, |
||||
| 37 | 25494161 |
US |
1 | |
Dizziness, Tremor, Condition aggravated, |
||||
PIMAVANSERIN TARTRATE, |
||||
| 38 | 25494179 |
US |
53 | 2 |
Condition aggravated, Product dose omission issue, |
||||
TOFACITINIB, METHOTREXATE, METHOTREXATE SODIUM, FOLIC ACID, MELOXICAM, |
||||
| 39 | 25494223 |
US |
||
Constipation, Condition aggravated, Vomiting, Gastrointestinal sounds abnormal, Insomnia, Intentional product use issue, |
||||
LOPERAMIDE HYDROCHLORIDE, LOPERAMIDE HCL, LOPERAMIDE HYDROCHLORIDE, LOPERAMIDE HCL, |
||||
| 40 | 25494296 |
CA |
64 | 2 |
Foot operation, Respiratory tract infection, Condition aggravated, |
||||
METHOTREXATE SODIUM, |
||||
| 41 | 25494297 |
FR |
54 | 1 |
Intervertebral discitis, Condition aggravated, |
||||
KETOPROFEN, KETOPROFEN, KETOPROFEN, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, DIAZEPAM, MORPHINE SULFATE, TRAMADOL HYDROCHLORIDE, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, |
||||
| 42 | 25494482 |
CA |
61 | 1 |
Condition aggravated, Cryoglobulinaemia, Drug ineffective, Fall, Malaise, Off label use, |
||||
RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, DIPHENHYDRAMINE HYDROCHLORIDE, DIPHENHYDRAMINE HYDROCHLORIDE CAPSULE, LIQUID FILLED, METHYLPREDNISOLONE, |
||||
| 43 | 25494487 |
DE |
||
Condition aggravated, Anal abscess, Anal fistula, Hypertension, Pyrexia, Upper respiratory tract infection, |
||||
CABOZANTINIB, NIVOLUMAB, NIVOLUMAB, NIVOLUMAB, NIVOLUMAB, NIVOLUMAB, NIVOLUMAB, NIVOLUMAB, NIVOLUMAB, NIVOLUMAB, NIVOLUMAB, NIVOLUMAB, HYDROXYUREA, |
||||
| 44 | 25494575 |
CN |
48 | 1 |
Dermatitis exfoliative generalised, Flushing, Rash, Condition aggravated, Pruritus, Drug eruption, |
||||
SECUKINUMAB, |
||||
| 45 | 25494611 |
AU |
||
Paralysis, Condition aggravated, Nervous system disorder, |
||||
FINGOLIMOD HCL, FINGOLIMOD, FINGOLIMOD HYDROCHLORIDE, |
||||
| 46 | 25494660 |
CA |
15 | 2 |
Condition aggravated, Off label use, Off label use, Off label use, |
||||
METHOTREXATE SODIUM, ROFLUMILAST, ARIPIPRAZOLE ORALLY DISINTEGRATING, ARIPIPRAZOLE, ARIPIPRAZOLE ORAL, DEXTROAMPHETAMINE, GUANFACINE HYDROCHLORIDE, GUANFACINE, ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, CELECOXIB, METHYLPHENIDATE, METHYLPHENIDATE HYDROCHLORIDE, |
||||
| 47 | 25494696 |
US |
2 | |
Hypersensitivity, Pruritus, Dyspnoea, Condition aggravated, Product use in unapproved indication, Intentional product misuse, |
||||
PERMETHRIN, |
||||
| 48 | 25494896 |
CA |
29 | 1 |
Condition aggravated, Constipation, Drug ineffective, Haematochezia, Neck pain, Vision blurred, Xerophthalmia, |
||||
ADALIMUMAB, ADALIMUMAB-FKJP, ADALIMUMAB-AATY, ADALIMUMAB, ADALIMUMAB-FKJP, ADALIMUMAB-AATY, |
||||
| 49 | 25495102 |
IL |
88 | 1 |
Bronchiectasis, Condition aggravated, Rash, Sleep disorder, Dyspnoea, Asthenia, |
||||
DUPILUMAB, |
||||
| 50 | 25495119 |
CA |
43 | 2 |
Abdominal discomfort, Abdominal pain upper, Accidental overdose, Alopecia, Anti-cyclic citrullinated peptide antibody positive, Arthralgia, Arthropathy, Aspiration, Asthenia, Blepharospasm, Blister, Blood cholesterol increased, Breast cancer stage III, Bursitis, C-reactive protein increased, Condition aggravated, Confusional state, Decreased appetite, Depression, Diarrhoea, Dizziness, Dry mouth, Duodenal ulcer perforation, Epilepsy, Facet joint syndrome, Fatigue, Fibromyalgia, Folliculitis, Gastrooesophageal reflux disease, General physical health deterioration, Glossodynia, Hand deformity, Headache, Helicobacter infection, Hepatic enzyme increased, Hypertension, Hypoaesthesia, Hypocholesterolaemia, Impaired healing, Inflammation, Infusion related reaction, Irritable bowel syndrome, Joint range of motion decreased, Joint swelling, Lip dry, Liver injury, Lower respiratory tract infection, Lung disorder, Memory impairment, Migraine, Mobility decreased, Muscle injury, Muscle spasms, Musculoskeletal pain, Nail disorder, Nasopharyngitis, Night sweats, Obesity, Osteoarthritis, Pain, Paraesthesia, Pemphigus, Pericarditis, Peripheral swelling, Peripheral venous disease, Product quality issue, Psoriatic arthropathy, Rash, Rheumatoid arthritis, Stomatitis, Swelling, Synovitis, Systemic lupus erythematosus, Taste disorder, Type 2 diabetes mellitus, Urticaria, Vomiting, Weight increased, Wheezing, Wound, Wound infection, Adverse event, Hospitalisation, |
||||
ABATACEPT, ABATACEPT, TRIAMCINOLONE ACETONIDE, TRIAMCINOLONE ACETONIDE OINTMENT USP, 0.05%, ACETAMINOPHEN AND CODEINE, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, TOCILIZUMAB, ALENDRONATE SODIUM, ALENDRONATE SODIUM, ALENDRONATE SODIUM, ALENDRONATE SODIUM, PREDNISONE, PREDNISONE, LEFLUNOMIDE, LORAZEPAM, ATOMOXETINE HYDROCHLORIDE, BOTULINUM TOXIN TYPE A, BUPRENORPHINE, CALCIUM CARBONATE, ANTACID, CALCIUM CARBONATE, ANTACID, CALCIUM GLUCONATE, CANDESARTAN, CELECOXIB, CELECOXIB, CETIRIZINE, CETIRIZINE HYDROCHLORIDE, CETIIRIZINE, CETIRIZINE, CETIRIZINE HYDROCHLORIDE, CETIIRIZINE, CETIRIZINE, CETIRIZINE HYDROCHLORIDE, CETIIRIZINE, CERTOLIZUMAB PEGOL, CERTOLIZUMAB PEGOL, CERTOLIZUMAB PEGOL, CORTISONE ACETATE, CORTISONE ACETATE, SECUKINUMAB, SECUKINUMAB, CYANOCOBALAMIN, CYANOCOBALAMIN, DESOXIMETASONE, DICLOFENAC POTASSIUM, DICLOFENAC POTASSIUM, FILM COATED, DICLOFENAC POTASSIUM TABLETS, ETANERCEPT, ERENUMAB-AOOE, ERENUMAB-AOOE, FOLIC ACID, FOLIC ACID, FOLIC ACID, FOLIC ACID, FOLIC ACID, FOLIC ACID, FOLIC ACID, ALENDRONATE SODIUM, ALENDRONATE SODIUM, ALENDRONATE SODIUM, ALENDRONATE SODIUM, GOLD, HYDROXYCHLOROQUINE, HYDROXYCHLOROQUINE SULFATE, ADALIMUMAB-ADAZ, IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE, IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE, SARILUMAB, LAMOTRIGINE, LAMOTRIGINE, LANSOPRAZOLE, LANSOPRAZOLE, LISINOPRIL, LISINOPRIL, LORAZEPAM, LORAZEPAM, MAGNESIUM CITRATE, MAJOR MAGNESIUM CITRATE ORAL SOLUTION - LEMON, BE HEALTH MAGNESIUM CITRATE ORAL SOLUTION - CHERRY, CVS MAGNESIUM CITRATE ORAL SOLUTION - CHERRY, FRESKARO MAGNESIUM CITRATE ORAL SOLUTION - GRAPE, CVS MAGNESIUM CITRATE ORAL SOLUTION - GRAPE, BE HEALTH MAGNESIUM CITRATE ORAL SOLUTION - GRAPE, CVS MAGNESIUM CITRATE ORAL SOLUTION - LEMON, FRESKARO MAGNESIUM CITRATE ORAL SOLUTION - LEMON, LEADER MAGNESIUM CITRATE ORAL SOLUTION - CHERRY, LEADER MAGNESIUM CITRATE ORAL SOLUTION - LEMON, BE HEALTH MAGNESIUM CITRATE ORAL SOLUTION - LEMON, FRESKARO MAGNESIUM CITRATE ORAL SOLUTION - CHERRY, LEADER MAGNESIUM CITRATE ORAL SOLUTION - GRAPE, HARRIS TEETER MAGNESIUM CITRATE ORAL SOLUTION - LEMON, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHYLPREDNISOLONE SODIUM SUCCINATE, METHYLPREDNISOLONE, MIRABEGRON, NAPROXEN, NAPROXEN SODIUM, NAPROXEN SODIUM, NAPROXEN SODIUM 220MG, NAPROXEN SODIUM, COATED TABLETS, NAPROXEN SODIUM TABLET, COATED, MEPOLIZUMAB, OXYCODONE, PANTOPRAZOLE SODIUM, PANTOPRAZOLE, PANTOPRAZOLE SODIUM IN 0.9% SODIUM CHLORIDE, PANTOPRAZOLE SODIUM INJECTION, PANTOPRAZOLE SODIUM, PANTOPRAZOLE, PANTOPRAZOLE SODIUM IN 0.9% SODIUM CHLORIDE, PANTOPRAZOLE SODIUM INJECTION, PHENYLEPHRINE HYDROCHLORIDE, PREDNISONE, PSEUDOEPHEDRINE HYDROCHLORIDE, PSEUDOEPHEDRINE HCL, PSEUDOEPHEDRINE HYDROCHLORIDE, PSEUDOEPHEDRINE HCL, PSEUDOEPHEDRINE HYDROCHLORIDE, PSEUDOEPHEDRINE HCL, QUETIAPINE FUMARATE, QUETIAPINE, RAMIPRIL, RANITIDINE, INFLIXIMAB, RISEDRONATE SODIUM, RITUXIMAB, RITUXIMAB, FISH OIL, FISH OIL, DICLOFENAC SODIUM, DICLOFENAC SODIUM TOPICAL, DICLOFENAC SODIUM TOPICAL GEL, 1%, DICLOFENAC, DICLOFENAC SODIUM 1%, LEFLUNOMIDE, LEFLUNOMIDE, GOLIMUMAB, GOLIMUMAB, USTEKINUMAB, SULFASALAZINE, SULFASALAZINE, SULFASALAZINE, SULFASALAZINE, SULFASALAZINE, SULFASALAZINE, SULFASALAZINE, SULFASALAZINE, SULFASALAZINE, SULFASALAZINE, SULFASALAZINE, SULFASALAZINE, TOFACITINIB, TOPIRAMATE, TOPIRAMATE, TOPIRAMATE, TRAMADOL HYDROCHLORIDE, TOFACITINIB, TOFACITINIB, |
||||
| 51 | 25495160 |
CO |
72 | 2 |
Muscle spasms, Blood pressure decreased, Pneumonia, Choking, Condition aggravated, Discomfort, Cough, Nasopharyngitis, Influenza, Chest discomfort, Oropharyngeal discomfort, Oropharyngeal pain, Feeling abnormal, Dyspnoea, Decreased immune responsiveness, Malaise, Pain in extremity, Blood pressure increased, Weight decreased, Malaise, Product supply issue, |
||||
RIBOCICLIB, RIBOCICLIB, RIBOCICLIB, RIBOCICLIB, RIBOCICLIB, LETROZOLE, LETROZOLE, VALSARTAN, VALSARTAN ORAL, LETROZOLE, LETROZOLE TABLETS, DAPAGLIFLOZIN, |
||||
| 52 | 25495183 |
AU |
64 | 2 |
Condition aggravated, Off label use, Off label use, |
||||
INFLIXIMAB-DYYB, INFLIXIMAB-DYYB, INFLIXIMAB-DYYB, HYDROCORTISONE SODIUM SUCCINATE, MESALAMINE, |
||||
| 53 | 25495208 |
CA |
54 | 2 |
Condition aggravated, Thrombosis, COVID-19, Off label use, |
||||
RITUXIMAB-PVVR, RITUXIMAB-PVVR, |
||||
| 54 | 25495358 |
CA |
75 | 1 |
Chest pain, Anaemia, Condition aggravated, Ulcer haemorrhage, Dementia Alzheimer^s type, Brain neoplasm, |
||||
METHOTREXATE SODIUM, HYDROXYCHLOROQUINE, FOLIC ACID, |
||||
| 55 | 25495374 |
CA |
49 | 2 |
Haematochezia, Off label use, Bronchitis, Terminal ileitis, Arthropathy, Dyspepsia, COVID-19, Emotional disorder, Viral infection, Constipation, Condition aggravated, |
||||
METHOTREXATE SODIUM, PANTOPRAZOLE, PREDNISONE, |
||||
| 56 | 25495414 |
32 | 2 | |
Cystitis interstitial, Condition aggravated, Illness, |
||||
DEXTROMETHORPHAN HYDROBROMIDE, BUPROPION HYDROCHLORIDE, |
||||
| 57 | 25495554 |
US |
9 | 2 |
Blister, Contusion, Pruritus, Swelling of eyelid, Condition aggravated, |
||||
DUPILUMAB, DUPILUMAB, |
||||
| 58 | 25495572 |
US |
73 | 2 |
Rash erythematous, Pruritus, Skin burning sensation, Condition aggravated, Product use in unapproved indication, |
||||
DUPILUMAB, |
||||
| 59 | 25495588 |
US |
52 | 2 |
Eye disorder, Condition aggravated, Inappropriate schedule of product administration, |
||||
DUPILUMAB, DUPILUMAB, |
||||
| 60 | 25495616 |
US |
1 | |
Condition aggravated, |
||||
DUPILUMAB, DUPILUMAB, DUPILUMAB, |
||||
| 61 | 25495642 |
US |
57 | 2 |
Nasal polyps, Condition aggravated, |
||||
DUPILUMAB, |
||||
| 62 | 25495643 |
US |
15 | 1 |
Dermatitis atopic, Condition aggravated, |
||||
DUPILUMAB, |
||||
| 63 | 25495655 |
US |
31 | 2 |
Rebound eczema, Pruritus, Sleep disorder due to a general medical condition, Mood altered, Condition aggravated, Emotional disorder, Condition aggravated, |
||||
DUPILUMAB, DUPILUMAB, |
||||
| 64 | 25495668 |
US |
63 | 2 |
Vision blurred, Condition aggravated, |
||||
DUPILUMAB, DUPILUMAB, |
||||
| 65 | 25495676 |
US |
48 | 1 |
Dermatitis contact, Condition aggravated, Neurodermatitis, Product use in unapproved indication, Intentional product misuse, |
||||
DUPILUMAB, DUPILUMAB, |
||||
| 66 | 25495684 |
US |
65 | 1 |
Injection site erythema, Condition aggravated, Injection site pain, |
||||
DUPILUMAB, DUPILUMAB, |
||||
| 67 | 25495698 |
US |
55 | 2 |
Paranasal sinus discomfort, Condition aggravated, Product use in unapproved indication, |
||||
DUPILUMAB, DUPILUMAB, DUPILUMAB, DOXYCYCLINE, DOXYCYCLINE HYCLATE, FLUTICASONE PROPIONATE AND SALMETEROL XINAFOATE, ALBUTEROL SULFATE, ALBUTEROL, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, INSULIN GLARGINE, BUTALBITAL, ACETAMINOPHEN, AND CAFFEINE, |
||||
| 68 | 25495755 |
US |
1 | |
Vision blurred, Condition aggravated, Ocular hyperaemia, Eye pruritus, |
||||
DUPILUMAB, DUPILUMAB, DUPILUMAB, |
||||
| 69 | 25495756 |
US |
42 | 1 |
Rash erythematous, Skin burning sensation, Condition aggravated, Pruritus, Product use in unapproved indication, |
||||
DUPILUMAB, DUPILUMAB, |
||||
| 70 | 25495786 |
US |
23 | 1 |
Sinusitis, Condition aggravated, |
||||
DUPILUMAB, TOBRAMYCIN, TOBRAMYCIN SULFATE, TOBRAMYCIN SOLUTION, |
||||
| 71 | 25495794 |
US |
16 | 2 |
Rash erythematous, Pruritus, Skin burning sensation, Condition aggravated, Product use in unapproved indication, |
||||
DUPILUMAB, DUPILUMAB, |
||||
| 72 | 25495819 |
US |
1 | |
Throat tightness, Condition aggravated, Urticaria, |
||||
DUPILUMAB, |
||||
| 73 | 25495876 |
US |
18 | 2 |
Menstruation irregular, Condition aggravated, Menstrual disorder, |
||||
DUPILUMAB, |
||||
| 74 | 25495905 |
US |
53 | 1 |
Nasal congestion, Condition aggravated, Nasopharyngitis, |
||||
DUPILUMAB, |
||||
| 75 | 25495917 |
US |
14 | 1 |
Nasal polyps, Condition aggravated, Rhinorrhoea, |
||||
DUPILUMAB, |
||||
| 76 | 25495925 |
US |
57 | 2 |
Nasal polyps, Condition aggravated, |
||||
DUPILUMAB, IXEKIZUMAB, |
||||
| 77 | 25495980 |
US |
46 | 2 |
Benign familial pemphigus, Condition aggravated, Product use in unapproved indication, |
||||
DUPILUMAB, DUPILUMAB, |
||||
| 78 | 25496064 |
US |
27 | 2 |
Sjogren^s syndrome, Condition aggravated, Drug ineffective for unapproved indication, Product use in unapproved indication, |
||||
ERGOCALCIFEROL, NORGESTIMATE AND ETHINYL ESTRADIOL, PILOCARPINE HYDROCHLORIDE, PILOCARPINE HYDROCHLORIDE OPHTHALMIC SOLUTION, HYDROXYCHLOROQUINE SULFATE, PREDNISONE, CERTOLIZUMAB PEGOL, LEVOTHYROXINE SODIUM, LEVOTHYROXINE SODIUM ANHYDROUS, LISDEXAMFETAMINE DIMESYLATE, LISDEXAMFETAMINE DIMESYLATE, |
||||
| 79 | 25496191 |
US |
53 | 1 |
Condition aggravated, Product dose omission issue, |
||||
TOFACITINIB, |
||||
| 80 | 25496212 |
CA |
40 | 2 |
Wound infection, Pruritus, Somnolence, Abdominal distension, Neck pain, Hepatitis, Dyspepsia, Muscular weakness, Back injury, Nail disorder, Coeliac disease, Mobility decreased, Derealisation, Wheezing, Headache, Depressed mood, Peripheral coldness, Adverse reaction, Gait inability, Condition aggravated, Temperature intolerance, Diarrhoea, Decreased appetite, Urticaria, Product label confusion, Malaise, Insomnia, Respiratory tract congestion, Heart rate increased, Weight increased, Blister, Suicidal ideation, Burning sensation, Feeling abnormal, Asthenia, Weight decreased, Gastrooesophageal reflux disease, Intentional product use issue, Hypoaesthesia, Fatigue, Grip strength decreased, Alopecia, Sleep disorder, Bursitis, Musculoskeletal stiffness, Pain in extremity, Nausea, Erythema, Fall, Off label use, Folliculitis, Gastrointestinal disorder, Finger deformity, Liver function test increased, Osteoarthritis, Injury, Pneumonia, |
||||
DICLOFENAC SODIUM, DICLOFENAC SODIUM TOPICAL, DICLOFENAC SODIUM TOPICAL GEL, 1%, DICLOFENAC, DICLOFENAC SODIUM 1%, DICLOFENAC SODIUM, DICLOFENAC SODIUM TOPICAL, DICLOFENAC SODIUM TOPICAL GEL, 1%, DICLOFENAC, DICLOFENAC SODIUM 1%, DICLOFENAC SODIUM, DICLOFENAC SODIUM TOPICAL, DICLOFENAC SODIUM TOPICAL GEL, 1%, DICLOFENAC, DICLOFENAC SODIUM 1%, DICLOFENAC SODIUM, DICLOFENAC SODIUM TOPICAL, DICLOFENAC SODIUM TOPICAL GEL, 1%, DICLOFENAC, DICLOFENAC SODIUM 1%, ERENUMAB-AOOE, CANDESARTAN, OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, ADALIMUMAB, ADALIMUMAB-FKJP, ADALIMUMAB-AATY, ADALIMUMAB, ADALIMUMAB-FKJP, ADALIMUMAB-AATY, SECUKINUMAB, SECUKINUMAB, LEFLUNOMIDE, LEFLUNOMIDE, LEFLUNOMIDE, LEFLUNOMIDE, LEFLUNOMIDE, OXYCODONE, RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, PHENYLEPHRINE HYDROCHLORIDE, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, ERGOCALCIFEROL, TOPIRAMATE, TOPIRAMATE SPINKLE, TOPIRAMATE, TOPIRAMATE SPINKLE, TOPIRAMATE, TOPIRAMATE SPINKLE, LEVOTHYROXINE SODIUM, LEVOTHYROXINE SODIUM, GABAPENTIN, CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CIPROFOLXACIN, CIPROFLOXACIN TABLETS, CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CIPROFOLXACIN, CIPROFLOXACIN TABLETS, MONTELUKAST SODIUM, MONTELUKAST, MONTELUKAST SODIUM, MONTELUKAST, CYCLOBENZAPRINE HYDROCHLORIDE, CYCLOBENZAPRINE, |
||||
| 81 | 25496668 |
JP |
31 | 2 |
Haematochezia, Drug ineffective, Condition aggravated, Frequent bowel movements, |
||||
MESALAMINE, BUDESONIDE, |
||||
| 82 | 25499988 |
69 | 2 | |
Condition aggravated, |
||||
AVACOPAN, |
||||
| 83 | 25490961 |
US |
12 | 1 |
Rebound atopic dermatitis, Product dose omission issue, Joint swelling, Condition aggravated, Arthralgia, |
||||
DUPILUMAB, |
||||
| 84 | 25490967 |
US |
2 | |
Cough, Productive cough, Condition aggravated, Secretion discharge, Dyspnoea, |
||||
DUPILUMAB, |
||||
| 85 | 25490971 |
US |
1 | |
Blister, Condition aggravated, |
||||
DUPILUMAB, |
||||
| 86 | 25490995 |
US |
23 | 2 |
Urticaria, Condition aggravated, Product use in unapproved indication, |
||||
DUPILUMAB, |
||||
| 87 | 25491019 |
US |
52 | 1 |
Staphylococcal infection, Condition aggravated, Bone pain, |
||||
DUPILUMAB, ERGOCALCIFEROL, |
||||
| 88 | 25491030 |
US |
31 | 1 |
Affective disorder, Behaviour disorder, Condition aggravated, Drug interaction, |
||||
VALPROIC ACID, VALPROIC ACID, CLONIDINE, RISPERIDONE, RISPERIDONE, CLONAZEPAM, CLONAZEPAM, CLONAZEPAM, MODAFINIL, SERTRALINE, LITHIUM, LITHIUM BROMATUM, LITHIUM, LITHIUM BROMATUM, |
||||
| 89 | 25491082 |
US |
22 | 2 |
Condition aggravated, Dry eye, |
||||
DUPILUMAB, |
||||
| 90 | 25491118 |
US |
2 | |
Guttate psoriasis, Condition aggravated, Dermatitis atopic, Inappropriate schedule of product administration, Product use in unapproved indication, |
||||
DUPILUMAB, DUPILUMAB, |
||||
| 91 | 25491157 |
US |
58 | 2 |
Joint swelling, Condition aggravated, Arthralgia, |
||||
SARILUMAB, |
||||
| 92 | 25491159 |
US |
1 | |
Asthma, Rebound effect, Cough, Condition aggravated, Incorrect dose administered, |
||||
DUPILUMAB, DUPILUMAB, UMECLIDINIUM, FLUTICASONE PROPIONATE AND SALMETEROL, ALBUTEROL SULFATE, |
||||
| 93 | 25491183 |
US |
38 | 2 |
Nasopharyngitis, Viral infection, Condition aggravated, Unevaluable event, |
||||
DUPILUMAB, DUPILUMAB, |
||||
| 94 | 25491190 |
US |
39 | 1 |
Dermatitis allergic, Condition aggravated, Pruritus, Drug ineffective, |
||||
DUPILUMAB, TADALAFIL, GABAPENTIN, ZIPRASIDONE HYDROCHLORIDE, ZIPRASIDONE, ZIPRASIDONE MESYLATE, |
||||
| 95 | 25491226 |
US |
||
Infantile spasms, Condition aggravated, |
||||
VIGABATRIN, |
||||
| 96 | 25491275 |
US |
67 | 2 |
Rash, Condition aggravated, |
||||
DUPILUMAB, FLUOXETINE HYDROCHLORIDE, LINACLOTIDE, FLUOXETINE HYDROCHLORIDE, |
||||
| 97 | 25491281 |
US |
6 | 2 |
Condition aggravated, Dry skin, Pruritus, |
||||
DUPILUMAB, |
||||
| 98 | 25491290 |
US |
57 | 1 |
Rosacea, Condition aggravated, |
||||
DUPILUMAB, |
||||
| 99 | 25491305 |
US |
41 | 2 |
Skin exfoliation, Condition aggravated, Pruritus, Plastic surgery, Injection site pain, |
||||
DUPILUMAB, DUPILUMAB, |
||||
| 100 | 25491364 |
US |
31 | 2 |
Erythema, Condition aggravated, Pruritus, |
||||
DUPILUMAB, DUPILUMAB, |
||||
disclaimer
Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.
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last_updated
2025-07-29