Drug Search by Year (Detail)

25491684

US

Insomnia, Sleep disorder, Palpitations, Middle insomnia, Micturition urgency, White blood cell count increased, Gastroenteritis viral, Confusional arousal, Hyperhidrosis, Confusional state, Disorientation, Parasomnia, Memory impairment, Drug interaction, Anxiety, Feeling abnormal, Somnolence, Dry mouth, Heart rate increased,

TIRZEPATIDE, TIRZEPATIDE, TIRZEPATIDE, TIRZEPATIDE, TIRZEPATIDE, SODIUM OXYBATE, SODIUM OXYBATE, PITOLISANT HYDROCHLORIDE, ACETYLCYSTEINE, FISH OIL, BUPROPION HYDROCHLORIDE, MAGNESIUM, NALTREXONE HYDROCHLORIDE, ERGOCALCIFEROL, MODAFINIL, CLOMIPHENE CITRATE,

25492010

ES

Drug interaction, Off label use,

DOXYCYCLINE, DOXYCYCLINE HYCLATE, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION,

25492217

US

Skin lesion, Breath odour, Drug interaction, Product taste abnormal,

CLOTRIMAZOLE, DRS. CLOTRIMAZOLE, FAMILY WELLNESS CLOTRIMAZOLE, CLOTRIMAZOLE TOPICAL, CLOTRIMAZOLE, DRS. CLOTRIMAZOLE, FAMILY WELLNESS CLOTRIMAZOLE, CLOTRIMAZOLE TOPICAL, CLOTRIMAZOLE, DRS. CLOTRIMAZOLE, FAMILY WELLNESS CLOTRIMAZOLE, CLOTRIMAZOLE TOPICAL, CLOTRIMAZOLE, DRS. CLOTRIMAZOLE, FAMILY WELLNESS CLOTRIMAZOLE, CLOTRIMAZOLE TOPICAL,

25492882

DK

Drug interaction, Toxicity to various agents, Dystonia,

VALPROIC ACID, PALIPERIDONE, PANTOPRAZOLE, VARENICLINE, VARENICLINE TARTRATE, FLUTICASONE PROPIONATE, BUDESONIDE,

25492906

US

Distributive shock, Renal injury, Sepsis, Schizophrenia, Toxicity to various agents, Haemodynamic instability, Leukocytosis, Agitation, Delusion, Paranoia, Hypotension, Tachycardia, Drug interaction, Intentional overdose, Intentional product misuse,

AMLODIPINE, LISINOPRIL,

25493118

ES

Hepatocellular injury, Coagulopathy, Intentional overdose, Drug interaction, Product use in unapproved indication,

ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE, NAPROXEN, NAPROXEN SODIUM,

25493149

IT

Electrocardiogram QT prolonged, Drug interaction, Drug ineffective,

ABIRATERONE ACETATE, ABIRATERONE, ABIRATERONE ACETATE, ABIRATERONE, ENZALUTAMIDE, ENZALUTAMIDE, DOCETAXEL, DOCETAXEL ANHYDROUS, DOCETAXEL, DOCETAXEL ANHYDROUS, LEUPROLIDE ACETATE, LEUPROLIDE ACETATE, LEUPROLIDE ACETATE,

25493361

GB

Drug interaction, Vomiting, Diarrhoea, Drug ineffective,

RIVAROXABAN, TIRZEPATIDE,

25493396

CH

Respiratory failure, Psychomotor retardation, Lacrimation increased, Miosis, Drug interaction, Bradycardia, Urinary retention,

ALPRAZOLAM, ALPRAZOLAM, ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, RISPERIDONE, MORPHINE SULFATE, METHYLPHENIDATE HYDROCHLORIDE, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS,

25493410

AU

Toxicity to various agents, Drug interaction,

TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, NIRMATRELVIR AND RITONAVIR,

25493434

ES

Angioedema, Drug interaction,

EVEROLIMUS, EVEROLIMUS TABLETS, EVEROLIMUS, EVEROLIMUS TABLETS, EVEROLIMUS, EVEROLIMUS TABLETS, EVEROLIMUS, EVEROLIMUS TABLETS, LISINOPRIL AND HYDROCHLOROTHIAZIDE, LISINOPRIL AND HYDROCHLOROTHIAZIDE TABLETS, LISINOPRIL AND HYDROCHLOROTHIAZIDE, LISINOPRIL AND HYDROCHLOROTHIAZIDE TABLETS, LISINOPRIL AND HYDROCHLOROTHIAZIDE, LISINOPRIL AND HYDROCHLOROTHIAZIDE TABLETS, LISINOPRIL AND HYDROCHLOROTHIAZIDE, LISINOPRIL AND HYDROCHLOROTHIAZIDE TABLETS, INSULIN HUMAN, INSULIN HUMAN, INSULIN HUMAN, INSULIN HUMAN, PREDNISONE, PREDNISONE, PREDNISONE, PREDNISONE, FLUOXETINE HYDROCHLORIDE, FLUOXETINE HYDROCHLORIDE, FLUOXETINE HYDROCHLORIDE, FLUOXETINE HYDROCHLORIDE, FLUTICASONE FUROATE, FLUTICASONE FUROATE, FLUTICASONE FUROATE, FLUTICASONE FUROATE, FLUTICASONE FUROATE, UMECLIDINIUM BROMIDE AND VILANTEROL TRIFENATATE, FLUTICASONE FUROATE, UMECLIDINIUM BROMIDE AND VILANTEROL TRIFENATATE, FLUTICASONE FUROATE, UMECLIDINIUM BROMIDE AND VILANTEROL TRIFENATATE, FLUTICASONE FUROATE, UMECLIDINIUM BROMIDE AND VILANTEROL TRIFENATATE, MONTELUKAST SODIUM, MONTELUKAST, MONTELUKAST SODIUM, MONTELUKAST, MONTELUKAST SODIUM, MONTELUKAST, MONTELUKAST SODIUM, MONTELUKAST, LORAZEPAM, LORAZEPAM, LORAZEPAM, LORAZEPAM, FULVESTRANT, FULVESTRANT, FULVESTRANT, FULVESTRANT,

25493525

US

Sedation, Somnolence, Fatigue, Antipsychotic drug level increased, Drug interaction,

CLOZAPINE, CLOZAPINE, CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CIPROFOLXACIN, CIPROFLOXACIN TABLETS, CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CIPROFOLXACIN, CIPROFLOXACIN TABLETS, DIVALPROEX SODIUM, LATANOPROST, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, CEPHALEXIN, CEPHALEXIN,

25493543

US

Serotonin syndrome, Drug interaction,

VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE, DULOXETINE HYDROCHLORIDE, DULOXETINE, ARIPIPRAZOLE ORALLY DISINTEGRATING, ARIPIPRAZOLE, ARIPIPRAZOLE ORAL, ZOLPIDEM TARTRATE, ZOLPIDEM TARTRATE, ZOLPIDEM TARTRATE, ARIPIPRAZOLE ORALLY DISINTEGRATING, ARIPIPRAZOLE, ARIPIPRAZOLE ORAL, VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE, DULOXETINE HYDROCHLORIDE, DULOXETINE, DULOXETINE HYDROCHLORIDE, DULOXETINE, DULOXETINE HYDROCHLORIDE, DULOXETINE,

25493824

US

Serotonin syndrome, Drug interaction,

DULOXETINE HYDROCHLORIDE, DULOXETINE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, ZOLPIDEM TARTRATE, ARIPIPRAZOLE ORALLY DISINTEGRATING, ARIPIPRAZOLE, ARIPIPRAZOLE ORAL,

25493830

IN

Neuropsychological symptoms, Hallucination, visual, Logorrhoea, Insomnia, Drug interaction, Delirium, Disorientation, Aphthous ulcer,

DULOXETINE HYDROCHLORIDE, DULOXETINE, PREGABALIN, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, MEMANTINE, MEMANTINE HYDROCHLORIDE, RIVASTIGMINE, DONEPEZIL HYDROCHLORIDE, RASAGILINE MESYLATE, RASAGILINE, MELATONIN, RABEPRAZOLE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, AMANTADINE, ARIPIPRAZOLE ORALLY DISINTEGRATING, ARIPIPRAZOLE, ARIPIPRAZOLE ORAL, ARMODAFINIL,

25494146

US

Haemorrhage, Drug interaction, Haemoglobin decreased, Fatigue,

RELUGOLIX, RELUGOLIX, DIGOXIN, ENZALUTAMIDE,

25494248

PL

Pneumonia, Drug interaction,

ESOMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, TELMISARTAN, INDAPAMIDE, DAPAGLIFLOZIN, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, ACETYLCYSTEINE,

25494404

DE

High density lipoprotein decreased, Drug interaction,

BEMPEDOIC ACID, FENOFIBRATE, EZETIMIBE, EVOLOCUMAB,

25494439

US

Serotonin syndrome, Drug interaction,

DULOXETINE HYDROCHLORIDE, DULOXETINE, VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE, ARIPIPRAZOLE ORALLY DISINTEGRATING, ARIPIPRAZOLE, ARIPIPRAZOLE ORAL, ZOLPIDEM TARTRATE,

25494595

US

Intentional overdose, Completed suicide, Toxicity to various agents, Drug interaction, Acute kidney injury, Haemodynamic instability, Dizziness,

AMLODIPINE, AMLODIPINE, AMLODIPINE, AMLODIPINE, APIXABAN, APIXABAN, APIXABAN, APIXABAN, TORSEMIDE, TORSEMIDE, TORSEMIDE, TORSEMIDE, SERTRALINE, SERTRALINE,

25495146

DE

Fungal oesophagitis, Drug interaction, Off label use,

FLUCONAZOLE, TACROLIMUS,

25495180

US

Immunosuppression, Drug interaction,

TOFACITINIB, METHOTREXATE,

25496295

US

Cellulitis, Acute kidney injury, Crohn^s disease, Drug interaction, Drug level increased, Hyponatraemia, Metabolic acidosis, Psychiatric symptom, Sedation, Sepsis,

CLOZAPINE, CLOZAPINE, CLOZAPINE, CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CIPROFOLXACIN, CIPROFLOXACIN TABLETS, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, LATANOPROST,

25491030

US

Affective disorder, Behaviour disorder, Condition aggravated, Drug interaction,

VALPROIC ACID, VALPROIC ACID, CLONIDINE, RISPERIDONE, RISPERIDONE, CLONAZEPAM, CLONAZEPAM, CLONAZEPAM, MODAFINIL, SERTRALINE, LITHIUM, LITHIUM BROMATUM, LITHIUM, LITHIUM BROMATUM,

25491436

CA

Anticholinergic syndrome, Drug interaction,

TOLTERODINE TARTRATE, TOLTERODINE, HALOPERIDOL, HALOPERIDOL LACTATE, RISPERIDONE, MIRTAZAPINE, PAROXETINE HYDROCHLORIDE, GALANTAMINE HYDROBROMIDE, QUETIAPINE FUMARATE, QUETIAPINE, RIVASTIGMINE TARTRATE, OXYBUTYNIN CHLORIDE, OLANZAPINE, RISPERIDONE, RANITIDINE HYDROCHLORIDE, DONEPEZIL HYDROCHLORIDE,

25490207

IT

Electrocardiogram QT prolonged, Drug interaction,

OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, RIBOCICLIB,

25490430

FR

Gastrointestinal haemorrhage, Drug interaction,

RIVAROXABAN, PAROXETINE HYDROCHLORIDE HEMIHYDRATE, PAROXETINE, PAROXETINE HYDROCHLORIDE, BISOPROLOL FUMARATE, IRBESARTAN, HYDROCHLOROTHIAZIDE, RAMIPRIL, SPIRONOLACTONE, EMPAGLIFLOZIN, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS,

25486418

GB

Serotonin syndrome, Drug interaction, Eructation, Nausea,

PROPRANOLOL HYDROCHLORIDE, TIRZEPATIDE, TIRZEPATIDE, PAROXETINE HYDROCHLORIDE HEMIHYDRATE, PAROXETINE, PAROXETINE HYDROCHLORIDE,

25486657

Drug interaction, Hyperammonaemia, Somnolence, Product use issue,

TOPIRAMATE, TOPIRAMATE SPINKLE, STIRIPENTOL,

25486658

Drug interaction, Hyperammonaemia, Product use issue,

TOPIRAMATE, TOPIRAMATE SPINKLE, STIRIPENTOL,

25486706

US

Behaviour disorder, Mood altered, Extrapyramidal disorder, Drug interaction,

SERTRALINE HYDROCHLORIDE, SERTRALINE HYDROCHLORIDE, SERTRALINE HYDROCHLORIDE, RISPERIDONE, RISPERIDONE, RISPERIDONE, RISPERIDONE, CLONIDINE, CLONAZEPAM, CLONAZEPAM, MODAFINIL, VALPROIC ACID, VALPROIC ACID, LITHIUM, LITHIUM BROMATUM, LITHIUM, LITHIUM BROMATUM, LITHIUM, LITHIUM BROMATUM,

25487106

IN

Drug interaction, Hallucination, visual, Insomnia,

DULOXETINE HYDROCHLORIDE, DULOXETINE, PREGABALIN,

25487189

GB

Drug interaction, Drug ineffective, Vomiting, Diarrhoea,

RIVAROXABAN, TIRZEPATIDE,

25487195

AU

Acute kidney injury, Major depression, Serotonin syndrome, Suicide attempt, Drug interaction, Intentional overdose, Metabolic acidosis, Physical deconditioning,

AMLODIPINE, ESOMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM, TRAMADOL HYDROCHLORIDE, ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, FLUOXETINE HYDROCHLORIDE, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, SEROTONIN (HYDROCHLORIDE), SEROTONIN, VALSARTAN, VALSARTAN ORAL,

25487252

JO

Rhabdomyolysis, Drug interaction, Hypercalcaemia,

SIMVASTATIN,

25487255

FR

Drug interaction,

AMLODIPINE, FLUCONAZOLE, LETERMOVIR,

25487258

FR

Drug interaction,

METOCLOPRAMIDE, METOCLOPRAMIDE HYDROCHLORIDE, FLUCONAZOLE, LETERMOVIR,

25487262

FR

Drug interaction, Acute myelomonocytic leukaemia,

FLUCONAZOLE, LETERMOVIR, LETERMOVIR, CYCLOSPORINE,

25487263

FR

Drug interaction, Acute myeloid leukaemia,

FLUCONAZOLE, LETERMOVIR, LETERMOVIR, CYCLOSPORINE,

25487266

FR

Drug interaction, Acute myeloid leukaemia,

FLUCONAZOLE, METOCLOPRAMIDE, METOCLOPRAMIDE HYDROCHLORIDE, CYCLOSPORINE, LETERMOVIR, LETERMOVIR,

25487439

US

Drug interaction,

RELUGOLIX,

25487615

OM

Autoimmune haemolytic anaemia, Drug interaction,

CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CIPROFOLXACIN, CIPROFLOXACIN TABLETS, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, LEFLUNOMIDE, METHYLPREDNISOLONE, BASILIXIMAB, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION,

25487740

US

Nocardiosis, Pulmonary nocardiosis, Disseminated nocardiosis, Anaphylactic reaction, Renal failure, Leukopenia, Thrombocytopenia, Hyperkalaemia, Angioedema, Abdominal discomfort, Cutaneous nocardiosis, Drug interaction, Adverse drug reaction, Rash, Pruritus, Urticaria,

PREDNISONE,

25487782

US

Affective disorder, Behaviour disorder, Drug interaction, Condition aggravated, Off label use,

CLONAZEPAM, SERTRALINE, CLONIDINE, MODAFINIL, RISPERIDONE, VALPROIC ACID, LITHIUM, LITHIUM BROMATUM, CLONAZEPAM, RISPERIDONE, LITHIUM, LITHIUM BROMATUM, LITHIUM, LITHIUM BROMATUM, VALPROIC ACID, CLONAZEPAM,

25487893

FR

Hyperkalaemia, Drug interaction,

EZETIMIBE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, BISOPROLOL FUMARATE, PANTOPRAZOLE SODIUM, PANTOPRAZOLE, PANTOPRAZOLE SODIUM IN 0.9% SODIUM CHLORIDE, PANTOPRAZOLE SODIUM INJECTION, ALPRAZOLAM, RELUGOLIX, DAPAGLIFLOZIN,

25488116

FR

Acute myocardial infarction, Drug interaction, Potentiating drug interaction,

PAROXETINE HYDROCHLORIDE HEMIHYDRATE, PAROXETINE, PAROXETINE HYDROCHLORIDE, RISPERIDONE, RISPERIDONE, RISPERIDONE, DIAZEPAM, DIAZEPAM, DIAZEPAM, PYRIDOSTIGMINE BROMIDE,

25488184

US

Sedation, Somnolence, Fatigue, Antipsychotic drug level increased, Drug interaction,

CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CIPROFOLXACIN, CIPROFLOXACIN TABLETS, CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CIPROFOLXACIN, CIPROFLOXACIN TABLETS, CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CIPROFOLXACIN, CIPROFLOXACIN TABLETS, CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CIPROFOLXACIN, CIPROFLOXACIN TABLETS, CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CIPROFOLXACIN, CIPROFLOXACIN TABLETS, CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CIPROFOLXACIN, CIPROFLOXACIN TABLETS, CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CIPROFOLXACIN, CIPROFLOXACIN TABLETS, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, DOXYCYCLINE, DOXYCYCLINE HYCLATE, VANCOMYCIN HYDROCHLORIDE, VANCOMYCIN, CEFTRIAXONE, CEFTRIAXONE SODIUM, CEFAZOLIN SODIUM, CEFAZOLIN, TOBRAMYCIN, TOBRAMYCIN SULFATE, TOBRAMYCIN SOLUTION, ERTAPENEM, ERTAPENEM SODIUM, CEPHALEXIN, CEPHALEXIN, ALBUTEROL SULFATE, DIVALPROEX SODIUM, BETAMETHASONE DIPROPIONATE, LATANOPROST, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES,

25489824

CA

Retroperitoneal haematoma, Abdominal wall haematoma, Drug interaction,

LEVOTHYROXINE SODIUM, LEVOTHYROXINE SODIUM, DIGOXIN, DIGOXIN, ALENDRONATE SODIUM, WARFARIN, WARFARIN, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE, METOPROLOL,

25490501

US

Pulmonary embolism, Arteriovenous fistula thrombosis, Drug interaction,

RIVAROXABAN, RIFAMPIN,

25490563

CN

Neuroleptic malignant syndrome, Drug interaction, Acute kidney injury, Pneumonia aspiration, Overdose,

SERTRALINE HYDROCHLORIDE, SERTRALINE HYDROCHLORIDE, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, LORAZEPAM, LORAZEPAM,

25490599

FR

Hyperkalaemia, Drug interaction,

PANTOPRAZOLE, RELUGOLIX, VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE, EZETIMIBE, BISOPROLOL FUMARATE, DAPAGLIFLOZIN, ALPRAZOLAM,

25481307

FR

Neutropenia, Cytopenia, Thrombocytopenia, Anaemia, Drug interaction,

BENDAMUSTINE HCL, BENDAMUSTINE HCL, CYCLOPHOSPHAMIDE FOR INJECTION, CYCLOPHOSPHAMIDE, CYCLOPHOSPHAMIDE INJECTION, SOLUTION, FLUDARABINE PHOSPHATE, RITUXIMAB, RITUXIMAB, RITUXIMAB, IBRUTINIB, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, PREDNISONE, VENETOCLAX, VENETOCLAX, VENETOCLAX, VENETOCLAX, VENETOCLAX, LACOSAMIDE, LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE,

25481565

US

Dehydration, Hypotension, Drug interaction, Nausea, Vomiting, Fatigue, Hypophagia, Product use issue,

SEMAGLUTIDE, MIFEPRISTONE, AMLODIPINE, CARVEDILOL, SACUBITRIL AND VALSARTAN, SPIRONOLACTONE, ASCORBIC ACID, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, INSULIN DEGLUDEC, FLUTICASONE FUROATE, UMECLIDINIUM BROMIDE AND VILANTEROL TRIFENATATE, ROSUVASTATIN, POTASSIUM CHLORIDE, POTASSIUM CHLORIDE EXTENDED-RELEASE, POTASSIUM CHLORIDE, DEXTROSE MONOHYDRATE, POTASSIUM CHLORIDE ORAL, PANTOPRAZOLE, INSULIN ASPART, FUROSEMIDE, EZETIMIBE,

25481942

US

Eye irritation, Vision blurred, Pruritus, Injection site bruising, Swelling face, Eye pain, Impaired work ability, Drug interaction,

ADALIMUMAB, DUPILUMAB, DUPILUMAB,

25481946

US

Drug level above therapeutic, Neurotoxicity, Drug interaction,

RITONAVIR, RITONAVIR 100 MG, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, PREDNISONE, PHENYTOIN,

25482715

PL

Drug-disease interaction, Drug level increased, Drug interaction,

ZOLPIDEM TARTRATE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, EZETIMIBE, EMPAGLIFLOZIN, SITAGLIPTIN, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG,

25482759

PL

Drug-disease interaction, Drug level increased, Drug interaction,

ZOLPIDEM TARTRATE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, RAMIPRIL, TORSEMIDE,

25482886

GB

Diverticulum, Disseminated tuberculosis, Cutaneous vasculitis, Rash, Drug interaction, Drug intolerance,

METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, RIFAMPIN, RIFAMPIN, RIFAMPIN, RIFAMPIN, SULFASALAZINE, SULFASALAZINE, SULFASALAZINE, SULFASALAZINE, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, ADALIMUMAB, ADALIMUMAB-FKJP, ADALIMUMAB-AATY, ADALIMUMAB-ADAZ, ADALIMUMAB, ADALIMUMAB-FKJP, ADALIMUMAB-AATY, ADALIMUMAB-ADAZ, ADALIMUMAB, ADALIMUMAB-FKJP, ADALIMUMAB-AATY, ADALIMUMAB-ADAZ, ADALIMUMAB, ADALIMUMAB-FKJP, ADALIMUMAB-AATY, ADALIMUMAB-ADAZ, HYDROXYCHLOROQUINE, HYDROXYCHLOROQUINE, HYDROXYCHLOROQUINE, HYDROXYCHLOROQUINE, LEVOFLOXACIN, LEVOFLOXACIN IN 5% DEXTROSE, LEVOFLOXACIN, LEVOFLOXACIN IN 5% DEXTROSE, LEVOFLOXACIN, LEVOFLOXACIN IN 5% DEXTROSE, LEVOFLOXACIN, LEVOFLOXACIN IN 5% DEXTROSE,

25482920

IT

Cardiogenic shock, Mitral valve incompetence, Drug interaction, Alcohol interaction,

DISULFIRAM,

25482938

US

Serotonin syndrome, Drug interaction,

BUPROPION HYDROCHLORIDE, FLUOXETINE HYDROCHLORIDE, FLUOXETINE, PROPOFOL, PROPOFOL,

25483042

GB

Drug interaction, Metabolic acidosis,

ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER,

25483097

US

Drug interaction, Drug ineffective,

RISPERIDONE, RISPERIDONE, RISPERIDONE, RISPERIDONE, MODAFINIL, DIVALPROEX SODIUM, DIVALPROEX SODIUM, CLONAZEPAM, CLONAZEPAM, CLONIDINE, CLONIDINE, SERTRALINE, SERTRALINE, SERTRALINE, LITHIUM, LITHIUM BROMATUM, LITHIUM, LITHIUM BROMATUM, LITHIUM, LITHIUM BROMATUM,

25483258

TW

Chromaturia, Intestinal obstruction, Bacteraemia, Acute respiratory failure, Rhabdomyolysis, Blood creatine phosphokinase increased, Ventricular tachycardia, Drug interaction,

ATORVASTATIN CALCIUM, ATORVASTATIN CALCIUM, ATORVASTATIN CALCIUM, ATORVASTATIN CALCIUM, ATORVASTATIN CALCIUM, ATORVASTATIN CALCIUM, ATORVASTATIN CALCIUM, ATORVASTATIN CALCIUM,

25483297

AU

Acute kidney injury, Major depression, Serotonin syndrome, Suicide attempt, Drug interaction, Intentional overdose, Metabolic acidosis, Physical deconditioning,

AMLODIPINE, FLUOXETINE HYDROCHLORIDE, FLUOXETINE, TRAMADOL HYDROCHLORIDE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, ESOMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, SEROTONIN (HYDROCHLORIDE), SEROTONIN, TOFACITINIB, VALSARTAN, VALSARTAN ORAL,

25483537

CA

Product prescribing error, Drug ineffective, Influenza, Wrong technique in product usage process, SARS-CoV-2 test positive, Off label use, Platelet count decreased, COVID-19, Mouth haemorrhage, Platelet count increased, Fatigue, Drug interaction,

METHOTREXATE, METHOTREXATE SODIUM, ELTROMBOPAG OLAMINE, ELTROMBOPAG OLAMINE, ELTROMBOPAG OLAMINE, ELTROMBOPAG OLAMINE, ELTROMBOPAG OLAMINE, ELTROMBOPAG OLAMINE, ELTROMBOPAG OLAMINE, ELTROMBOPAG OLAMINE, ELTROMBOPAG OLAMINE, PREDNISONE, DEXAMETHASONE, DEXAMETHASONE 1.5 MG, RITUXIMAB,

25483585

US

Affective disorder, Behaviour disorder, Drug interaction, Condition aggravated,

RISPERIDONE, CLONAZEPAM, CLONIDINE, MODAFINIL, SERTRALINE, VALPROIC ACID, LITHIUM, LITHIUM BROMATUM,

25483759

CA

Acute kidney injury, Tumour lysis syndrome, Myalgia, Blood bilirubin increased, Vomiting, Haematuria, Seizure, Infection, Cerebral ischaemia, Cystitis noninfective, Alanine aminotransferase increased, Aspartate aminotransferase increased, Pulmonary embolism, Thrombosis, Anaemia, Drug interaction, Febrile neutropenia,

VINCRISTINE SULFATE, RITONAVIR, RITONAVIR 100 MG, DOXORUBICIN HYDROCHLORIDE, DOXORUBICIN, NEVIRAPINE, RITUXIMAB, CYCLOPHOSPHAMIDE FOR INJECTION, CYCLOPHOSPHAMIDE, CYCLOPHOSPHAMIDE INJECTION, SOLUTION, FOSAMPRENAVIR CALCIUM, ATAZANAVIR SULFATE, ATAZANAVIR, DARUNAVIR, DARUNAVIR 600 MG, DARUNAVIR 800 MG, EFAVIRENZ, RALTEGRAVIR, ZIDOVUDINE, PREDNISONE, LOPINAVIR AND RITONAVIR,

25484839

FR

Hyperkalaemia, Drug interaction,

VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, EZETIMIBE, EZETIMIBE, EZETIMIBE, EZETIMIBE, PANTOPRAZOLE, PANTOPRAZOLE, PANTOPRAZOLE, PANTOPRAZOLE, ALPRAZOLAM, ALPRAZOLAM, ALPRAZOLAM, ALPRAZOLAM, BISOPROLOL FUMARATE, BISOPROLOL FUMARATE, BISOPROLOL FUMARATE, BISOPROLOL FUMARATE, RELUGOLIX, RELUGOLIX, RELUGOLIX, RELUGOLIX, DAPAGLIFLOZIN, DAPAGLIFLOZIN, DAPAGLIFLOZIN, DAPAGLIFLOZIN,

25485043

FR

Drug interaction,

FLUCONAZOLE, METOCLOPRAMIDE, METOCLOPRAMIDE HYDROCHLORIDE, LETERMOVIR, LETERMOVIR, CYCLOSPORINE,

25485055

FR

Drug interaction, Myelodysplastic syndrome,

FLUCONAZOLE, LETERMOVIR, LETERMOVIR, CYCLOSPORINE,

25485167

ES

Hepatic cytolysis, Rhabdomyolysis, Suicide attempt, Intentional overdose, Drug interaction,

ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, FLUOXETINE HYDROCHLORIDE, FLUOXETINE, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, GABAPENTIN,

25485280

GB

Drug interaction, Abdominal pain upper, Vomiting, Diarrhoea,

TIRZEPATIDE, TIRZEPATIDE,

25485515

US

Dehydration, Blood pressure decreased, Drug interaction, Nausea, Vomiting, Fatigue, Hypophagia,

SACUBITRIL AND VALSARTAN, AMLODIPINE, CARVEDILOL, MIFEPRISTONE, SEMAGLUTIDE, SPIRONOLACTONE, ASCORBIC ACID, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, ERGOCALCIFEROL, INSULIN DEGLUDEC, FLUTICASONE FUROATE, UMECLIDINIUM BROMIDE AND VILANTEROL TRIFENATATE, ROSUVASTATIN, PANTOPRAZOLE, INSULIN ASPART, FUROSEMIDE, EZETIMIBE, CALCIUM,

25486153

US

Affective disorder, Behaviour disorder, Drug interaction, Condition aggravated, Extrapyramidal disorder,

RISPERIDONE, RISPERIDONE, RISPERIDONE, RISPERIDONE, RISPERIDONE, RISPERIDONE, VALPROIC ACID, VALPROIC ACID, CLONAZEPAM, CLONAZEPAM, CLONAZEPAM, CLONIDINE, MODAFINIL, SERTRALINE, LITHIUM, LITHIUM BROMATUM, LITHIUM, LITHIUM BROMATUM,

25476238

CA

Aneurysm, Femur fracture, Drug interaction, Cerebrovascular accident,

AMLODIPINE, APALUTAMIDE, EDOXABAN TOSYLATE,

25476352

IR

Hypertensive crisis, Serotonin syndrome, Depressed level of consciousness, Clonus, Heart rate decreased, Drug interaction,

LINEZOLID, DOXEPIN, DOXEPIN HYDROCHLORIDE, AMLODIPINE, VALSARTAN, VALSARTAN ORAL, ALPRAZOLAM, CLONAZEPAM, INSULIN GLARGINE-YFGN, INSULIN GLARGINE, INSULIN ASPART, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, PIPERACILLIN SODIUM AND TAZOBACTAM SODIUM, PIPERACILLIN AND TAZOBACTAM, PIPERACILLIN SODIUM,TAZOBACTAM SODIUM, PIPERACILLIN SODIUM AND TAZOBACTAM SODIUM, PIPERACILLIN AND TAZOBACTAM, PIPERACILLIN SODIUM,TAZOBACTAM SODIUM, MIDAZOLAM, MIDAZOLAM HYDROCHLORIDE, MORPHINE SULFATE,

25476410

IR

Hypertensive crisis, Serotonin syndrome, Eyelid myoclonus, Hyperreflexia, Agitation, Sinus tachycardia, Hypertension, Drug interaction,

FENTANYL CITRATE, FENTANYL CITRATE, LINEZOLID, METHYLPREDNISOLONE, REMDESIVIR, REMDESIVIR, CEFEPIME HYDROCHLORIDE, CEFEPIME, MORPHINE, MIDAZOLAM, MIDAZOLAM HYDROCHLORIDE,

25476475

CN

Hypoglycaemic coma, Drug interaction, Loss of consciousness, Intestinal ischaemia, Cerebral infarction, Gastrointestinal haemorrhage,

DICLOFENAC, DICLOFENAC SODIUM, GLIPIZIDE, RIVAROXABAN, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG,

25476559

CH

Shock haemorrhagic, Drug interaction,

ALTEPLASE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, CLOPIDOGREL, CLOPIDOGREL BISULFATE,

25476770

DE

Blood pressure decreased, Dyspnoea, Loss of consciousness, Drug interaction,

TAMSULOSIN HYDROCHLORIDE,

25476771

IT

COVID-19, Pneumothorax, Dyspnoea, Pneumomediastinum, Chest pain, Subcutaneous emphysema, Off label use, Drug interaction, Product use in unapproved indication,

AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, HYDROXYCHLOROQUINE, METHYLPREDNISOLONE, ACETYLCYSTEINE,

25477288

IT

Abdominal pain, Haematochezia, Transaminases increased, Drug interaction,

IMATINIB, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER,

25477573

AU

Toxicity to various agents, Acute kidney injury, Escherichia urinary tract infection, COVID-19, Diarrhoea, Nausea, Vomiting, Drug interaction,

TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, NIRMATRELVIR AND RITONAVIR, APIXABAN, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, MYCOPHENOLIC ACID, MYCOPHENILIC ACID, PREDNISONE, RABEPRAZOLE SODIUM, RABEPRAZOLE, SIMVASTATIN, SOTALOL HYDROCHLORIDE, SOTALOL HYDROCHLORIDE TABLES AF, SOTALOL HYDROCHLORIDE TABLETS AF,

25478002

DE

Generalised tonic-clonic seizure, Drug interaction,

LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE,

25478212

CA

Transcription medication error, Hepatic pain, Paraesthesia, Delayed recovery from anaesthesia, Product size issue, Therapy interrupted, Alopecia, Joint swelling, Temperature regulation disorder, Brain fog, Feeling abnormal, Headache, Vaginal disorder, Blood pressure systolic increased, Chills, Breast pain, Rash, Product availability issue, Anorectal disorder, Product physical issue, Hypoxia, Product substitution issue, Photosensitivity reaction, Product colour issue, Swelling, Hyperhidrosis, Condition aggravated, Cognitive disorder, Product formulation issue, Gastrointestinal pain, Anxiety, Withdrawal syndrome, Peripheral swelling, Sedation complication, Product taste abnormal, Rash erythematous, Inadequate analgesia, Dysphagia, Suspected product tampering, Drug interaction, Bradypnoea, Urinary tract pain, Abdominal pain, Underdose, Dyspnoea, Heart rate increased, Tremor, Product physical consistency issue, Product shape issue, Dyspepsia, Arthralgia, Pain, Burning sensation, Product dosage form issue, Drug ineffective, Haemorrhage, Respiratory depression, Blood pressure diastolic increased, Attention deficit hyperactivity disorder,

ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, MORPHINE, NIRMATRELVIR AND RITONAVIR, REMIFENTANIL HYDROCHLORIDE, LISDEXAMFETAMINE DIMESYLATE, AMITRIPTYLINE HYDROCHLORIDE, CITALOPRAM, CITALOPRAM HYDROBROMIDE,

25479058

IT

Haematochezia, Drug interaction, Abdominal pain, Transaminases increased,

ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, IMATINIB,

25479337

Product substitution issue, Product prescribing issue, Hallucination, Dyskinesia, Dyskinesia, Mental status changes, Hypertension, Emotional distress, Anxiety, Irritability, Paranoia, Drug withdrawal syndrome, Toxicity to various agents, Drug withdrawal syndrome, Abnormal behaviour, Drug interaction,

BUPRENORPHINE,

25479829

CH

Urinary incontinence, Enuresis, Urinary retention, Self-destructive behaviour, Aggression, Drug interaction, Blindness,

ESOMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM, RISPERIDONE, OLANZAPINE, CLOBAZAM, CLONIDINE,

25479918

GB

Drug interaction, Vomiting, Diarrhoea, Drug ineffective,

TIRZEPATIDE, RIVAROXABAN,

25480070

ES

Hepatic cytolysis, Rhabdomyolysis, Intentional overdose, Drug interaction,

FLUOXETINE HYDROCHLORIDE, GABAPENTIN, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, PENICILLIN V POTASSIUM,

25480071

ES

Depressed level of consciousness, Intentional overdose, Drug interaction,

FLUOXETINE HYDROCHLORIDE, PREGABALIN, TOPIRAMATE, TOPIRAMATE SPINKLE, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE,

25480123

PT

Drug interaction, Serotonin syndrome,

LORAZEPAM, IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE, MIRTAZAPINE, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER,

25480542

CH

Respiratory failure, Psychomotor retardation, Lacrimation increased, Miosis, Bradycardia, Urinary retention, Drug interaction, Drug interaction,

MORPHINE SULFATE, ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, ALPRAZOLAM, ALPRAZOLAM, RISPERIDONE, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, METHYLPHENIDATE HYDROCHLORIDE,

25470368

DE

Head discomfort, Blood pressure fluctuation, Discomfort, Drug interaction,

AMLODIPINE BESYLATE, PANTOPRAZOLE, CEFUROXIME AXETIL, SIMVASTATIN,

25470395

IN

Gingival hypertrophy, Drug interaction,

AMLODIPINE BESYLATE, SIMVASTATIN, SIMVASTATIN, ATENOLOL, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG,

25470396

CH

Drug interaction, Hepatic enzyme increased,

AMLODIPINE BESYLATE, SIMVASTATIN,

25470570

US

Hypercalcaemia, Rhabdomyolysis, Drug interaction,

SIMVASTATIN, WARFARIN,

25471038

US

Drug interaction,

TREPROSTINIL, TREPROSTINIL, AMBRISENTAN, MACITENTAN,

25471065

CH

Drug interaction, Hyperthyroidism,

AMIODARONE HYDROCHLORIDE, SEMAGLUTIDE, SEMAGLUTIDE,

25471066

CH

Drug interaction, Hyperthyroidism,

AMIODARONE HYDROCHLORIDE, SEMAGLUTIDE, SEMAGLUTIDE,