RxISK

Making Medicines Safer for All of Us

Drug Search by Year (Detail)

Side effect search by year (detail)

Drug:

Reaction: DRUG INTERACTION

20250101 - 20251231

No. 1 - 100

Next page: 2 next page>>
No.
safetyreportid
occurcountry
patientonsetage
patientsex 1:M 2:F
Adverse reaction
Drug (openfda.generic_name, medicinalproduct)
1
25138814
84 2
Atrioventricular block second degree, Skin lesion, Sinus bradycardia, Dizziness, Nausea, Drug interaction, Cardioactive drug level increased,
POSACONAZOLE, POSACONAZOLE DELAYED-RELEASE, DIGOXIN, METOPROLOL TARTRATE, METOPROLOL,
2
25138883
CA
 56 2
Depressed level of consciousness, Drug intolerance, Drug interaction, Electrocardiogram QT prolonged, Fall, Mental disorder, Nephropathy toxic, Serotonin syndrome, Toxicity to various agents, Contraindicated product administered, Off label use, Hypertension, Drug ineffective, Drug ineffective for unapproved indication,
ERENUMAB-AOOE, CANDESARTAN, CANDESARTAN, MIRTAZAPINE, MIRTAZAPINE, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, OXYCODONE, PROPRANOLOL HYDROCHLORIDE, PROPRANOLOL HYDROCHLORIDE, PROPRANOLOL HYDROCHLORIDE, PROPRANOLOL HYDROCHLORIDE, PROPRANOLOL HYDROCHLORIDE, DULOXETINE HYDROCHLORIDE, GABAPENTIN, GABAPENTIN, INDOMETHACIN, PERINDOPRIL ERBUMINE, PERINDOPRIL ERBUMINE, PERINDOPRIL ERBUMINE, PERINDOPRIL ERBUMINE, PERINDOPRIL ERBUMINE, DULOXETINE HYDROCHLORIDE, DULOXETINE, TOPIRAMATE, TOPIRAMATE SPINKLE, TOPIRAMATE, TOPIRAMATE SPINKLE, BOTULINUM TOXIN TYPE A, DIVALPROEX SODIUM,
3
25138945
US
Hypotension, Electrocardiogram QT prolonged, Drug interaction, Product dose omission in error,
TIZANIDINE HYDROCHLORIDE, HYDROCHLOROTHIAZIDE, AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, LISINOPRIL, METOPROLOL TARTRATE, METOROPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE, METOROPROLOL TARTRATE, METOPROLOL, HYDRALAZINE HYDROCHLORIDE, METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, DOXYCYCLINE, DOXYCYCLINE HYCLATE,
4
25139006
US
 2
Drug interaction,
FLUTICASONE FUROATE, UMECLIDINIUM BROMIDE AND VILANTEROL TRIFENATATE, NASAL SPRAY,
5
25139044
US
 43 2
Serotonin syndrome, Respiratory distress, Lactic acidosis, Tachycardia, Leukocytosis, Drug interaction, Muscle rigidity, Autonomic nervous system imbalance, Drug abuse, Shock, Blood lactic acid increased, Muscle tightness, Overdose,
DIPHENHYDRAMINE HYDROCHLORIDE, DIPHENHYDRAMINE HYDROCHLORIDE CAPSULE, LIQUID FILLED, DULOXETINE HYDROCHLORIDE, DULOXETINE, DULOXETINE HYDROCHLORIDE, DULOXETINE, ASENAPINE, ASENAPINE MALEATE, FENTANYL,
6
25139212
US
Drug interaction, Xanthopsia, Dizziness, Nausea,
DIGOXIN, POSACONAZOLE, POSACONAZOLE DELAYED-RELEASE, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE, METOPROLOL,
7
25139312
PT
 69 2
Dizziness, Drug interaction,
MIRTAZAPINE, SERTRALINE HYDROCHLORIDE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, PANTOPRAZOLE SODIUM, PANTOPRAZOLE, PANTOPRAZOLE SODIUM IN 0.9% SODIUM CHLORIDE, PANTOPRAZOLE SODIUM INJECTION,
8
25139558
US
 58 2
Cardiogenic shock, Atrioventricular block complete, Drug interaction,
VERAPAMIL HYDROCHLORIDE, NIRMATRELVIR AND RITONAVIR,
9
25139577
AU
 44 2
Myocarditis, Drug interaction, Off label use, Treatment failure,
ARIPIPRAZOLE ORALLY DISINTEGRATING, ARIPIPRAZOLE, ARIPIPRAZOLE ORAL, LURASIDONE HYDROCHLORIDE, AMISULPRIDE, OLANZAPINE, ASENAPINE, ASENAPINE MALEATE, CLOZAPINE, PAROXETINE HYDROCHLORIDE HEMIHYDRATE, PAROXETINE, PAROXETINE HYDROCHLORIDE, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, PALIPERIDONE,
10
25139590
ES
Pancytopenia, Drug interaction, Intentional product use issue,
RITUXIMAB, ALLOPURINOL, AZATHIOPRINE, LOSARTAN, BUDESONIDE AND FORMOTEROL FUMARATE DIHYDRATE, NEBIVOLOL HYDROCHLORIDE, CITALOPRAM, CITALOPRAM HYDROBROMIDE, EDOXABAN TOSYLATE, FUROSEMIDE, COLCHICINE, TRAMADOL HYDROCHLORIDE, PREDNISONE, PREDNISONE, ALBUTEROL SULFATE, BRIMONIDINE TARTRATE, IRON, FLUTICASONE PROPIONATE, SEMAGLUTIDE, EMPAGLIFLOZIN AND METFORMIN HYDROCHLORIDE, EMPAGLIFLOZIN, METFORMIN HYDROCHLORIDE, REPAGLINIDE, INSULIN GLARGINE,
11
25139604
US
BRASH syndrome, Diarrhoea, Drug interaction,
HYDROCHLOROTHIAZIDE, CARVEDILOL, VALSARTAN,
12
25139736
JP
 57 2
Calcineurin inhibitor induced pain syndrome, Drug interaction, Immunosuppressant drug level increased, Product use in unapproved indication,
TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, CLARITHROMYCIN, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, TOCILIZUMAB, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES,
13
25139774
JP
 1
Drug interaction, Immunosuppressant drug level increased, Renal impairment, Bronchopulmonary aspergillosis,
TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, EVEROLIMUS, EVEROLIMUS TABLETS, RABEPRAZOLE, AMLODIPINE, SITAGLIPTIN, REPAGLINIDE, MIGLITOL, LEMBOREXANT, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, LEMBOREXANT,
14
25139832
US
 63 1
Dysphagia, Asthenia, Hypersensitivity, Muscle spasms, Drug interaction, Inappropriate schedule of product administration,
RIPRETINIB,
15
25140196
US
 57 1
Arteriospasm coronary, Acute myocardial infarction, Drug interaction,
ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, SUMATRIPTAN, SUMATRIPTAN SUCCINATE,
16
25140305
GB
Drug interaction, Immunosuppression, Mycobacterium marinum infection,
PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION,
17
25140905
FR
 86 1
Acute kidney injury, Renal tubular necrosis, Drug interaction,
VALSARTAN,
18
25141366
ES
Generalised oedema, Weight increased, Drug interaction, Product use in unapproved indication,
HYDROCORTISONE, ANTIPRURITIC (ANTI-ITCH), ANTI-ITCH CREAM, HYDROCORTISONE 1%, HYDROCORTISONE CONTINUOUS SPRAY, ANTI-PRURITIC, HYDROCORTISONE LOTION, HYDROCORTISONE ACETATE, HYDROCORTISONE LOTION KIT, ANTI ITCH, ANTI-ITCH, COOL RELIEF GEL WITH ALOE, HYDROCORTISONE CREAM 1%, HYDROCORTISONE SPRAY, DRS. HYDROCORTISONE,
19
25141865
PL
 63 1
Hepatic enzyme increased, Diabetes mellitus inadequate control, Hepatotoxicity, Aspartate aminotransferase increased, Alanine aminotransferase increased, Drug interaction,
DAROLUTAMIDE, ROSUVASTATIN, DOCETAXEL, DOCETAXEL ANHYDROUS, TORSEMIDE,
20
25142210
US
 73 2
Drug interaction,
TUCATINIB, AMLODIPINE,
21
25142226
US
 85 2
BRASH syndrome, Drug interaction,
HYDROCHLOROTHIAZIDE, VALSARTAN, CARVEDILOL,
22
25138187
PT
 51 1
Face oedema, Product use in unapproved indication, Drug interaction,
PREGABALIN, PREGABALIN, FENTANYL, MORPHINE SULFATE, CLONAZEPAM, SENNOSIDES, SENNA LEAF, SENNA, SENNOSIDES 8.6 MG TABLETS,
23
25138235
US
 85 2
BRASH syndrome, Drug interaction, Drug level increased,
CARVEDILOL, HYDROCHLOROTHIAZIDE, VALSARTAN,
24
25137188
US
 43 2
Serotonin syndrome, Drug interaction,
TRAZODONE HYDROCHLORIDE, DIPHENHYDRAMINE, DIPHENHYDRAMINE HYDROCHLORIDE, DULOXETINE HYDROCHLORIDE, DULOXETINE, DULOXETINE HYDROCHLORIDE, DULOXETINE, ASENAPINE, ASENAPINE MALEATE, FENTANYL,
25
25137293
GB
 91 1
Haematemesis, Drug interaction, Faeces discoloured,
CLOPIDOGREL, CLOPIDOGREL BISULFATE, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, OSELTAMIVIR PHOSPHATE, FOLIC ACID, SIMVASTATIN, LEVOTHYROXINE, LANSOPRAZOLE,
26
25137647
US
Drug interaction, Mental status changes, Fatigue, Asthenia,
LENALIDOMIDE, BORTEZOMIB FOR INJECTION, BORTEZOMIB,
27
25137692
US
 77 1
Sinus bradycardia, Atrioventricular block first degree, Bundle branch block right, Electrocardiogram QT prolonged, Drug interaction,
LACOSAMIDE, APIXABAN,
28
25137720
NL
Acute kidney injury, Rhabdomyolysis, Toxicity to various agents, Drug interaction,
ROSUVASTATIN, ABIRATERONE ACETATE, ABIRATERONE, PREDNISONE,
29
25137734
AU
 45 1
Osteomyelitis, Polyomavirus-associated nephropathy, Scedosporium infection, Complications of transplanted kidney, Drug interaction, Oedema peripheral, Staphylococcal infection,
TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, PREDNISONE, VORICONAZOLE,
30
25137830
PL
 67 1
Anaphylactic shock, Hypersensitivity, Swelling face, Drug interaction,
AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, ALIROCUMAB,
31
25137979
NL
 76 1
Acute kidney injury, Rhabdomyolysis, Drug interaction,
ABIRATERONE ACETATE, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, ROSUVASTATIN, CHLORTHALIDONE, METOPROLOL TARTRATE, METOPROLOL, RIVAROXABAN, TRIPTORELIN,
32
25141173
40 2
Asthenia, Fatigue, Brain fog, Drug interaction,
NIRMATRELVIR AND RITONAVIR,
33
25132584
US
 70 2
Drug interaction, Product use in unapproved indication,
RIFAMPIN, RIFAMPIN, ETHAMBUTOL HYDROCHLORIDE, ETHAMBUTOL HYDROCHLORIDE, AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, AMIKACIN, AMIKACIN,
34
25132824
FR
 75 1
Hypoglycaemia, Drug interaction,
INSULIN GLARGINE, IRBESARTAN, BISOPROLOL FUMARATE,
35
25132859
Tachycardia, Drug interaction,
SOLRIAMFETOL,
36
25132909
US
 2
Drug interaction,
CORTISONE ACETATE,
37
25132989
US
 77 1
Bundle branch block right, Electrocardiogram QT prolonged, Drug interaction, Sinus bradycardia, Atrioventricular block first degree,
LACOSAMIDE, APIXABAN,
38
25133104
US
 74 1
Electrocardiogram QT prolonged, Drug interaction,
DOFETILIDE, DOFETILIDE, BOSUTINIB,
39
25133416
US
 57 1
Arteriospasm coronary, Acute myocardial infarction, Drug interaction,
SUMATRIPTAN, SUMATRIPTAN SUCCINATE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG,
40
25133635
US
 72
Blood pressure increased, Drug interaction,
BUDESONIDE, GLYCOPYRROLATE, AND FORMOTEROL FUMARATE, NORTRIPTYLINE HYDROCHLORIDE,
41
25133718
US
 64 1
Torsade de pointes, Electrocardiogram QT prolonged, Drug interaction,
ABIRATERONE ACETATE, ABIRATERONE,
42
25133880
SK
 50 1
Drug interaction, Drug ineffective, Electrocardiogram QT prolonged,
BISOPROLOL FUMARATE, EMTRICITABINE, TENOFOVIR ALAFENAMIDE, PROPAFENONE,
43
25133975
GB
Haematemesis, Faeces discoloured, Drug interaction,
CLOPIDOGREL, CLOPIDOGREL BISULFATE, EDOXABAN TOSYLATE, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, OSELTAMIVIR PHOSPHATE, FOLIC ACID, SIMVASTATIN, LEVOTHYROXINE, LANSOPRAZOLE,
44
25134549
FR
 74 1
Hyperkalaemia, Drug interaction,
SPIRONOLACTONE,
45
25134581
US
 59 2
Drug interaction, Therapeutic product effect incomplete,
CRIZOTINIB, CRIZOTINIB, LORLATINIB, LORLATINIB, CARBOPLATIN, CARBOPLATIN, ENTRECTINIB, ENTRECTINIB,
46
25134652
US
 64 1
Electrocardiogram QT prolonged, Torsade de pointes, Drug interaction,
ABIRATERONE ACETATE, ABIRATERONE, ABIRATERONE ACETATE, ABIRATERONE, ABIRATERONE ACETATE, ABIRATERONE, ABIRATERONE ACETATE, ABIRATERONE,
47
25134653
AU
 20 2
Toxicity to various agents, Hypotension, Depressed level of consciousness, Negative cardiac inotropic effect, Electrocardiogram PR prolongation, Electrocardiogram QRS complex prolonged, Hypokalaemia, Intentional overdose, Intentional product misuse, Drug interaction,
PROPRANOLOL HYDROCHLORIDE, PROPRANOLOL HYDROCHLORIDE, PROPRANOLOL HYDROCHLORIDE, HYDROXYCHLOROQUINE,
48
25134818
IT
Tremor, Drug interaction, Off label use,
OLANZAPINE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, LITHIUM CARBONATE,
49
25134832
GB
 91 1
Haematemesis, Drug interaction, Faeces discoloured, Rectal haemorrhage,
CLOPIDOGREL, CLOPIDOGREL BISULFATE, EDOXABAN TOSYLATE, FOLIC ACID, LANSOPRAZOLE, LEVOTHYROXINE, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, SIMVASTATIN, OSELTAMIVIR PHOSPHATE,
50
25134905
CA
 44 1
Chest discomfort, Clostridium difficile infection, Drug interaction, Dyspnoea, Erythema, Fatigue, Flushing, Intentional product use issue, Off label use,
VANCOMYCIN HYDROCHLORIDE, INFLIXIMAB-DYYB, INFLIXIMAB-DYYB,
51
25135081
US
 35 2
Major depression, Suicidal ideation, Anhedonia, Depressed mood, Feeling of despair, Frustration tolerance decreased, Drug interaction, Insomnia, Irritability, Hyponatraemia,
LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE, OXCARBAZEPINE, SERTRALINE, SERTRALINE, CLOBAZAM, CLONAZEPAM,
52
25135296
US
 84 2
Drug interaction, Toxicity to various agents, Atrioventricular block second degree, Sinus bradycardia,
POSACONAZOLE, POSACONAZOLE DELAYED-RELEASE, DIGOXIN, METOPROLOL TARTRATE, METOPROLOL,
53
25136226
GB
 91 1
Haematemesis, Drug interaction, Faeces discoloured,
CLOPIDOGREL, CLOPIDOGREL BISULFATE, EDOXABAN TOSYLATE, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, OSELTAMIVIR PHOSPHATE, FOLIC ACID, SIMVASTATIN, LEVOTHYROXINE, LANSOPRAZOLE,
54
25136523
77 1
Hypoglycaemia, Confusional state, Delirium, Unresponsive to stimuli, Drug interaction,
GLIMEPIRIDE, CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CIPROFOLXACIN, CIPROFLOXACIN TABLETS,
55
25126442
CA
 63 1
Blood triglycerides increased, Drug interaction, Malignant neoplasm of eye, Off label use, Pruritus, Insomnia, Anxiety, Therapeutic response shortened,
CITALOPRAM, CITALOPRAM HYDROBROMIDE, ABROCITINIB, ABROCITINIB, ABROCITINIB,
56
25126453
US
 43 2
Drug abuse, Drug interaction, Serotonin syndrome, Lactic acidosis, Leukocytosis,
DIPHENHYDRAMINE HYDROCHLORIDE, DIPHENHYDRAMINE HYDROCHLORIDE CAPSULE, LIQUID FILLED, ASENAPINE, ASENAPINE MALEATE, DULOXETINE HYDROCHLORIDE, DULOXETINE, DULOXETINE HYDROCHLORIDE, DULOXETINE,
57
25126535
US
Drug interaction, Acute myocardial infarction,
SUMATRIPTAN, SUMATRIPTAN SUCCINATE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG,
58
25126685
AU
 37 2
Myocarditis, Mania, Extrapyramidal disorder, Drug interaction, Treatment failure,
LURASIDONE HYDROCHLORIDE, RISPERIDONE, CLOZAPINE, OLANZAPINE,
59
25126686
IT
Tremor, Drug interaction,
ARIPIPRAZOLE ORALLY DISINTEGRATING, ARIPIPRAZOLE, ARIPIPRAZOLE ORAL, VALPROIC ACID,
60
25127340
ES
 76 1
Rhabdomyolysis, Drug interaction,
ABIRATERONE ACETATE, ABIRATERONE ACETATE, ROSUVASTATIN, PREDNISONE, PREDNISONE,
61
25127413
CA
 33 2
Transcription medication error, Hypoxia, Bradypnoea, Sedation complication, Respiratory depression, Blood pressure diastolic increased, Inadequate analgesia, Blood pressure systolic increased, Delayed recovery from anaesthesia, Heart rate increased, Pain, Feeling abnormal, Drug interaction,
MORPHINE, REMIFENTANIL HYDROCHLORIDE, CITALOPRAM, CITALOPRAM HYDROBROMIDE, ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM,
62
25127571
GB
 2
Sudden cardiac death, Arrhythmia, Sleep apnoea syndrome, Drug interaction,
IVABRADINE, PAROXETINE HYDROCHLORIDE,
63
25127597
MT
Pancreatitis, Drug interaction,
QUETIAPINE FUMARATE, QUETIAPINE, QUETIAPINE FUMARATE, QUETIAPINE, VALPROIC ACID,
64
25127598
US
 17 1
Psychotic disorder, Drug interaction,
OLANZAPINE, QUETIAPINE FUMARATE, QUETIAPINE, DIVALPROEX SODIUM, RISPERIDONE,
65
25127599
US
 34 1
Gastrointestinal hypomotility, Drug interaction,
CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, QUETIAPINE FUMARATE, QUETIAPINE, QUETIAPINE FUMARATE, QUETIAPINE, BENZTROPINE,
66
25127614
AU
 54 1
Cardiomegaly, Toxicity to various agents, Drug interaction,
DULOXETINE HYDROCHLORIDE, DULOXETIN HYDROCHLORIDE, DULOXETINE, QUETIAPINE FUMARATE, QUETIAPINE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, ALPRAZOLAM, ALCOHOL, ETHYL ALCOHOL, ISOPROPYL ALCOHOL, FLUVOXAMINE MALEATE,
67
25127844
US
 84 2
Atrial fibrillation, Dizziness, Sinus bradycardia, Atrioventricular block second degree, Extrasystoles, Ventricular extrasystoles, Nausea, Xanthopsia, Drug interaction,
POSACONAZOLE, POSACONAZOLE DELAYED-RELEASE, DIGOXIN,
68
25128367
US
 58 2
Cardiogenic shock, Atrioventricular block complete, Drug interaction,
NIRMATRELVIR AND RITONAVIR,
69
25128373
US
 57 1
Arteriospasm coronary, Drug interaction,
SUMATRIPTAN, SUMATRIPTAN SUCCINATE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG,
70
25128386
AU
Cytopenia, Neutropenia, Toxicity to various agents, Adverse drug reaction, Drug interaction,
AZACITIDINE, AZACITIDINE FOR, VENETOCLAX,
71
25129111
US
 2
Abdominal pain, Diarrhoea, Drug interaction, Injection site bruising, Wrong technique in product usage process,
CALCIUM CARBONATE, ERGOCALCIFEROL, ALENDRONATE SODIUM, FOLIC ACID, METHOTREXATE SODIUM, RITUXIMAB,
72
25129199
US
 83 2
Drug interaction, Off label use, Drug ineffective,
ABEMACICLIB, PRIMIDONE,
73
25129868
US
 2
Haematochezia, Drug interaction,
LISDEXAMFETAMINE DIMESYLATE, LISDEXAMFETAMINE, LISDEXAMFETAMINE DIMESYLATE CAPSULES, BUPROPION HYDROCHLORIDE, BUPROPION, ESCITALOPRAM OXALATE, ESCITALOPRAM,
74
25130232
US
Drug interaction, Lip swelling, Hypersensitivity,
BEMPEDOIC ACID AND EZETIMIBE, HYDROGEN PEROXIDE, HYDROGEN PEROXIDE 3.0%, 1169 HYDROGEN PEROXIDE SPRAY,
75
25130330
US
 67 1
Drug interaction, Syncope, Blood pressure systolic decreased, Fall, Contusion, Dizziness,
BEMPEDOIC ACID AND EZETIMIBE, VALSARTAN, LABETALOL, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG,
76
25130494
US
 52 1
Gastrointestinal haemorrhage, Drug interaction, Cellulitis, Syncope, Condition aggravated,
PIPERACILLIN SODIUM AND TAZOBACTAM SODIUM, PIPERACILLIN AND TAZOBACTAM, PIPERACILLIN SODIUM,TAZOBACTAM SODIUM, RIVAROXABAN,
77
25130567
US
 70 2
Pulmonary cavitation, Condition aggravated, Pathogen resistance, Myocardial infarction, Drug interaction,
AMIKACIN, AMIKACIN, AMIKACIN, AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, RIFABUTIN, RIFAMPIN, RIFAMPIN,
78
25130797
US
 64 1
Drug interaction, Hot flush,
APALUTAMIDE, RELUGOLIX,
79
25130881
US
 58 2
Atrioventricular block complete, Cardiogenic shock, Drug interaction,
NIRMATRELVIR AND RITONAVIR,
80
25131037
CA
 33 2
Abdominal pain, Alopecia, Anorectal disorder, Anxiety, Arthralgia, Attention deficit hyperactivity disorder, Brain fog, Breast pain, Burning sensation, Chills, Cognitive disorder, Drug ineffective, Drug interaction, Dyspepsia, Dysphagia, Dyspnoea, Gastrointestinal pain, Haemorrhage, Headache, Hepatic pain, Hyperhidrosis, Joint swelling, Pain, Paraesthesia, Peripheral swelling, Photosensitivity reaction, Product availability issue, Product formulation issue, Product physical issue, Product shape issue, Product size issue, Product substitution issue, Suspected product tampering, Product taste abnormal, Rash, Rash erythematous, Swelling, Temperature regulation disorder, Therapy interrupted, Tremor, Urinary tract pain, Vaginal disorder, Withdrawal syndrome,
NIRMATRELVIR AND RITONAVIR, ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, AMITRIPTYLINE HYDROCHLORIDE, LISDEXAMFETAMINE DIMESYLATE,
81
25131163
US
 43 2
Serotonin syndrome, Drug abuse, Drug interaction,
DIPHENHYDRAMINE HYDROCHLORIDE, DIPHENHYDRAMINE HYDROCHLORIDE CAPSULE, LIQUID FILLED, DULOXETINE HYDROCHLORIDE, DULOXETINE, DULOXETINE HYDROCHLORIDE, DULOXETINE, ASENAPINE, ASENAPINE MALEATE, FENTANYL,
82
25131328
US
 16 1
Toxicity to various agents, Drug interaction,
PHENYTOIN, CEFTRIAXONE, CEFTRIAXONE SODIUM, SODIUM CHLORIDE, SODIUM CHLORIDE INJECTION, SODIUM CHLORIDE TABLET, NORMAL SALT TABLETS, ONDANSETRON HYDROCHLORIDE, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES,
83
25131335
65 1
Atrial fibrillation, Drug interaction,
VALSARTAN, SULFAMETHOXAZOLE AND TRIMETHOPRIM, VALSARTAN,
84
25131511
ES
 1
Drug-induced liver injury, Myelosuppression, Drug interaction, Drug ineffective,
PEMETREXED, PEMETREXED DISODIUM, PACLITAXEL, VINORELBINE, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, MIRTAZAPINE, APIXABAN, CEFTRIAXONE, CEFTRIAXONE SODIUM, TRIMETHOPRIM, ALPRAZOLAM, PEMBROLIZUMAB, AMIKACIN, CARBOPLATIN, AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, LINEZOLID, LINEZOLID, LINEZOLID, LINEZOLID,
85
25131541
CA
 86 1
Fall, Gait disturbance, Nystagmus, Tremor, Toxicity to various agents, Drug interaction,
PHENYTOIN, TRAZODONE HYDROCHLORIDE,
86
25120945
CN
 61 1
COVID-19, Pulmonary mucormycosis, Respiratory moniliasis, Acinetobacter infection, Stenotrophomonas infection, Cytomegalovirus infection, Drug interaction,
TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, PREDNISONE, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE,
87
25121044
AU
Suicide attempt, Major depression, Serotonin syndrome, Acute kidney injury, Drug interaction, Physical deconditioning, Metabolic acidosis, Intentional overdose,
ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, AMLODIPINE, ESCITALOPRAM OXALATE, ESCITALOPRAM, ESOMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM, FLUOXETINE HYDROCHLORIDE, TRAMADOL HYDROCHLORIDE, VALSARTAN, VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE, TOFACITINIB,
88
25121656
US
 81 2
Dizziness, Confusional state, Fatigue, Visual impairment, Impaired driving ability, Brain fog, Thinking abnormal, Speech disorder, Drug interaction,
COLCHICINE, SERTRALINE HYDROCHLORIDE, ROSUVASTATIN,
89
25122078
NL
 48 2
Oedema peripheral, Renal impairment, Weight increased, Ascites, Pleural effusion, Stomatitis, Mucosal inflammation, Drug clearance decreased, Toxicity to various agents, Drug interaction,
IMATINIB, METHOTREXATE, METHOTREXATE SODIUM, CYTARABINE, ETOPOSIDE,
90
25122111
GB
 34 2
Sudden cardiac death, Drug interaction,
IVABRADINE, PAROXETINE HYDROCHLORIDE HEMIHYDRATE, PAROXETINE, PAROXETINE HYDROCHLORIDE,
91
25122142
AU
Cytopenia, Neutropenia, Drug interaction,
AZACITIDINE, AZACITIDINE FOR, VENETOCLAX,
92
25122494
AU
 44 2
Myocarditis, Treatment failure, Off label use, Drug interaction,
ARIPIPRAZOLE ORALLY DISINTEGRATING, ARIPIPRAZOLE, ARIPIPRAZOLE ORAL, QUETIAPINE FUMARATE, QUETIAPINE, LURASIDONE HYDROCHLORIDE, AMISULPRIDE, ASENAPINE, ASENAPINE MALEATE, OLANZAPINE, CLOZAPINE, PAROXETINE HYDROCHLORIDE HEMIHYDRATE, PAROXETINE, PAROXETINE HYDROCHLORIDE, PALIPERIDONE,
93
25122810
TR
 72 1
Toxicity to various agents, Nausea, Vomiting, Confusional state, Psychomotor hyperactivity, Agitation, Hepatic enzyme increased, Drug level increased, Drug interaction,
PHENYTOIN, POLYETHYLENE GLYCOL,
94
25123741
US
 85 2
BRASH syndrome, Drug interaction,
VALSARTAN, HYDROCHLOROTHIAZIDE, CARVEDILOL,
95
25123971
CA
Anticholinergic syndrome, Drug interaction,
MIRTAZAPINE, DONEPEZIL HYDROCHLORIDE, GALANTAMINE HYDROBROMIDE, HALOPERIDOL, HALOPERIDOL LACTATE, LOPERAMIDE HYDROCHLORIDE, LOPERAMIDE HCL, OLANZAPINE, OXYBUTYNIN, PAROXETINE HYDROCHLORIDE, QUETIAPINE FUMARATE, QUETIAPINE, RANITIDINE HYDROCHLORIDE, RISPERIDONE, RISPERIDONE, RIVASTIGMINE TARTRATE, TOLTERODINE, TRAZODONE HYDROCHLORIDE, CARBIDOPA AND LEVODOPA,
96
25124172
CA
Drug interaction, Contraindicated product administered, Haemorrhage,
NIRMATRELVIR AND RITONAVIR, RIVAROXABAN,
97
25124343
US
 67 2
Drug interaction, Dehydration, Diarrhoea,
PALBOCICLIB, CHLORTHALIDONE,
98
25124530
CN
 67 2
Angina pectoris, Tachycardia, Drug interaction, Chest pain,
DILTIAZEM HYDROCHLORIDE, DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE TABLETS, AMINOPHYLLINE, CHLORPHENIRAMINE MALEATE,
99
25124563
US
 57 1
Arteriospasm coronary, Acute myocardial infarction, Drug interaction,
ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, SUMATRIPTAN, SUMATRIPTAN SUCCINATE,
100
25124570
FR
 75 1
Drug interaction, Hypoglycaemia,
INSULIN GLARGINE, INSULIN ASPART, IRBESARTAN, BISOPROLOL FUMARATE,

disclaimer

Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.

terms

https://open.fda.gov/terms/

license

https://open.fda.gov/license/

last_updated

2025-04-28

Next page: 2 next page>>