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Drug:

Reaction: THERAPY INTERRUPTED

20260101 - 20261231

No. 1 - 100

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No.
safetyreportid
occurcountry
patientonsetage
patientsex 1:M 2:F
Adverse reaction
Drug (openfda.generic_name, medicinalproduct)
1
26940305
US
 66 2
Therapy interrupted, Product distribution issue,
MAVACAMTEN, MAVACAMTEN,
2
26940585
US
Malaise, Therapy interrupted, Product availability issue,
THEOPHYLLINE ANHYDROUS,
3
26940606
CA
 46
Surgery, Condition aggravated, Abscess limb, Insurance issue, Treatment delayed, Therapy interrupted,
ADALIMUMAB-AATY, ADALIMUMAB-AATY,
4
26940665
US
 1
Injection site reaction, Therapy interrupted, Product dose omission issue,
ABALOPARATIDE, ABALOPARATIDE,
5
26940786
US
 2
Therapy interrupted, Blood pressure abnormal, Pulmonary oedema,
ACALABRUTINIB, FUROSEMIDE, NIFEDIPINE,
6
26940793
US
 2
Neuralgia, Weight increased, Fluid retention, Adverse event, Therapy interrupted,
ABALOPARATIDE, ABALOPARATIDE,
7
26941430
US
 70 2
Coma, Intestinal perforation, Liver transplant, Cardiac disorder, Gait disturbance, Chest pain, Hepatic steatosis, Therapy interrupted,
EVOLOCUMAB, EVOLOCUMAB, EVOLOCUMAB,
8
26941435
US
 50 2
Pericarditis, Drug dose omission by device, Device difficult to use, Therapy interrupted,
ETANERCEPT, ETANERCEPT,
9
26941795
CA
 47
Haematochezia, Abdominal pain, Product distribution issue, Therapy interrupted, Inappropriate schedule of product administration, Therapeutic response shortened,
INFLIXIMAB-DYYB, INFLIXIMAB-DYYB, INFLIXIMAB-DYYB, MESALAMINE, MESALAMINE,
10
26941811
US
 1
Therapy interrupted, Inappropriate schedule of product administration, Nasopharyngitis, COVID-19,
TILDRAKIZUMAB-ASMN,
11
26941904
AE
 2
Rheumatoid arthritis, Product dose omission issue, Therapy interrupted,
ADALIMUMAB, ADALIMUMAB-AATY, ADALIMUMAB-ADAZ, ADALIMUMAB-FKJP,
12
26941973
US
 42 2
Rheumatoid arthritis, Therapy interrupted,
ETANERCEPT,
13
26942723
AU
 12 2
Bone giant cell tumour benign, Hypercalcaemia, Therapy interrupted,
DENOSUMAB,
14
26942952
US
 45
Muscle tightness, Back pain, Therapy interrupted, Overdose,
BUROSUMAB, BUROSUMAB,
15
26943348
US
 1
Ankylosing spondylitis, Product availability issue, Therapy interrupted,
CERTOLIZUMAB PEGOL,
16
26943975
US
 2
Productive cough, Off label use, Therapy interrupted,
BRENSOCATIB,
17
26944026
US
 73 2
Psoriatic arthropathy, Alopecia, Oedema, Arthralgia, Urinary tract infection, Therapy interrupted, Psoriasis, Nail disorder, Otorrhoea, Dermatitis, Drug ineffective, Pruritus, Dry skin, Chills,
BIMEKIZUMAB, BIMEKIZUMAB, METHOTREXATE, METHOTREXATE SODIUM,
18
26944413
GB
 72
Cataract, Fatigue, Therapy interrupted, Product prescribing issue,
INFLIXIMAB-DYYB,
19
26944422
US
 42 2
Seizure, Therapy interrupted, Fall, Product use issue, Overdose, Insurance issue,
BRIVARACETAM, BRIVARACETAM, BRIVARACETAM,
20
26944429
GB
 1
Psoriatic arthropathy, Product prescribing issue, Product availability issue, Therapy interrupted,
BIMEKIZUMAB,
21
26944604
US
 2
Rheumatoid arthritis, Therapy interrupted, Loss of personal independence in daily activities, Inability to afford medication,
CERTOLIZUMAB PEGOL,
22
26944645
CA
 74 2
Cystitis, Drug ineffective, Insurance issue, Therapy interrupted,
CERTOLIZUMAB PEGOL, CERTOLIZUMAB PEGOL,
23
26944773
US
 52 1
Insurance issue, Therapy interrupted,
LENALIDOMIDE,
24
26944809
US
 48 1
Hospitalisation, Liver disorder, Ammonia increased, Therapy interrupted,
RIFAXIMIN,
25
26945366
US
 63 1
Therapy interrupted, Product distribution issue,
LENALIDOMIDE,
26
26945588
US
 2
Feeling abnormal, Therapy interrupted,
ABALOPARATIDE, ABALOPARATIDE,
27
26945630
US
 1
Product use in unapproved indication, Therapy interrupted,
ABALOPARATIDE, CARVEDILOL, CELECOXIB, MONTELUKAST, RIMEGEPANT SULFATE, RIZATRIPTAN, SUMATRIPTAN, SUMATRIPTAN SUCCINATE,
28
26945734
US
 2
Laboratory test abnormal, Therapy interrupted,
ABALOPARATIDE,
29
26945759
US
 75 2
Product distribution issue, Therapy interrupted,
POMALIDOMIDE,
30
26945770
US
 73 2
Insomnia, Palpitations, Pruritus, Intentional product misuse, Therapy interrupted,
ABALOPARATIDE, ABALOPARATIDE, ABALOPARATIDE, ABALOPARATIDE, ACETAMINOPHEN, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE, ACETAMINOPHEN,
31
26946002
US
 2
Ageusia, Illness, Injection site pruritus, Drug hypersensitivity, Product supply issue, Therapy interrupted,
ABALOPARATIDE, ABALOPARATIDE, ABALOPARATIDE, HYDROCODONE BITARTRATE AND ACETAMINOPHEN, CYCLOSPORINE, SIMVASTATIN, CYCLOBENZAPRINE, HYDROCHLOROTHIAZIDE,
32
26946127
US
 59
Generalised tonic-clonic seizure, Seizure, Concussion, Fracture, Fall, Head injury, Generalised tonic-clonic seizure, Seizure, Product dose omission issue, Incorrect dose administered, Therapy interrupted, Off label use,
CENOBAMATE, CENOBAMATE, CENOBAMATE, OXCARBAZEPINE, DIVALPROEX SODIUM,
33
26946400
US
 77 2
Hospitalisation, Gait disturbance, Therapy interrupted, Product use issue,
ABALOPARATIDE,
34
26946453
US
 2
Therapy interrupted,
ABALOPARATIDE,
35
26946721
US
 54 2
Anxiety, Frustration tolerance decreased, Influenza, Feeling abnormal, Palpitations, Fatigue, Malaise, Pain in extremity, Arthralgia, Incorrect dose administered, Therapy interrupted,
ABALOPARATIDE, ABALOPARATIDE, ABALOPARATIDE, ABALOPARATIDE, LORAZEPAM,
36
26946963
US
 2
Therapy interrupted,
ABALOPARATIDE, CALCIUM,
37
26946970
US
 68 2
Spinal fusion surgery, Blood pressure decreased, Weight increased, Fall, Hand fracture, Therapy interrupted, Off label use,
ABALOPARATIDE, ABALOPARATIDE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, VITAMIN C, ERGOCALCIFEROL, MELATONIN, FOLIC ACID, CARVEDILOL, VALSARTAN, VALSARTAN ORAL, METHOTREXATE, METHOTREXATE SODIUM, HYDROCHLOROTHIAZIDE,
38
26947023
US
 74 2
Therapy interrupted, Liquid product physical issue, Drug effect less than expected,
ABALOPARATIDE, AMLODIPINE BESYLATE, METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, FAMOTIDINE, LEVOTHYROXINE SODIUM, LEVOTHYROXINE SODIUM ANHYDROUS, HYDROCHLOROTHIAZIDE, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, FISH OIL, ASCORBIC ACID, BIOTIN,
39
26947025
US
 52 1
Therapy interrupted,
ABALOPARATIDE,
40
26947156
US
 2
Hospitalisation, Bone density abnormal, Fall, Back pain, Therapy interrupted,
ABALOPARATIDE,
41
26947414
US
 2
Dysstasia, Pain, Therapy interrupted,
ABALOPARATIDE,
42
26947703
56
Illness, Therapy interrupted,
LENIOLISIB, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, DIPHENHYDRAMINE HYDROCHLORIDE, CAPLACIZUMAB, CEFTRIAXONE SODIUM, CLOTRIMAZOLE, DRS. CLOTRIMAZOLE, FAMILY WELLNESS CLOTRIMAZOLE, CLOTRIMAZOLE TOPICAL, FERROUS SULFATE, FOLIC ACID, IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN TABLET, FILM COATED, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE, LIDOCAINE, LIDOCAINE HYDROCHLORIDE, BURN RELIEF, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE, LIDICAINE, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE, LIDOCAINE 4%, LIDOCAINE, MENTHOL, THIAMINE HYDROCHLORIDE,
43
26947704
US
 61 2
Surgery, Swelling face, Eye swelling, Head discomfort, Therapy interrupted,
ABALOPARATIDE, ABALOPARATIDE, CARBOXYMETHYLCELLULOSE SODIUM AND GLYCERIN, CARBOXYMETHYLCELLULOSE SODIUM, GLYCERIN, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, ALBUTEROL SULFATE, DULOXETINE HYDROCHLORIDE, DULOXETINE, GABAPENTIN, CELECOXIB, ATORVASTATIN CALCIUM, ATORVASTATIN CALCIUM, FILM COATED, CYCLOBENZAPRINE HYDROCHLORIDE, CYCLOBENZAPRINE,
44
26947789
US
 2
Nausea, Therapy interrupted,
ABALOPARATIDE, ABALOPARATIDE, ERGOCALCIFEROL, ESTRADIOL, ESTRADIOL GEL 0.1%, ESTRADIOL TRANSDERMAL, ESTRADIOL,, PROGESTERONE,
45
26947832
US
 2
Influenza like illness, Therapy interrupted,
ABALOPARATIDE, ABALOPARATIDE,
46
26948004
US
 74 2
Feeling cold, Brain fog, Tremor, Dizziness postural, Anxiety, Blood pressure fluctuation, Weight decreased, Blood pressure decreased, Abdominal discomfort, Decreased appetite, Feeling abnormal, Blood pressure increased, Dizziness, Heart rate increased, Constipation, Headache, Vertigo, Fatigue, Nausea, Therapy interrupted, Intentional dose omission,
ABALOPARATIDE, ABALOPARATIDE, ICOSAPENT ETHYL, ICOSAPENT ETHYL CAPSULES, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, EVOLOCUMAB,
47
26948198
US
 59 2
Insurance issue, Therapy interrupted,
LENALIDOMIDE,
48
26948265
US
 2
Therapy interrupted, Product supply issue,
ABALOPARATIDE, FLUTICASONE PROPIONATE, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, PHYTONADIONE,
49
26951656
83 2
Fluid retention, Renal disorder, Peripheral swelling, Therapy interrupted, Sciatica,
MAVACAMTEN, CLOPIDOGREL, CLOPIDOGREL BISULFATE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG,
50
26951798
1
Hospitalisation, Therapy interrupted,
MOMELOTINIB,
51
26952037
74 1
Infection, Therapy interrupted,
AVACOPAN,
52
26952040
38 2
Abdominal pain, Vomiting, Impaired gastric emptying, Therapy interrupted,
ABALOPARATIDE,
53
26952117
70 2
Metabolic encephalopathy, Pneumonia, Sepsis, Therapy interrupted,
MAVACAMTEN,
54
26952126
68 1
Therapy interrupted, Hepatic enzyme increased, Hepatic cirrhosis, Abdominal distension, Confusional state, Wound, Faeces discoloured, Inguinal hernia, Septic shock, Peritonitis bacterial, Intestinal perforation,
BEVACIZUMAB-AWWB, ATEZOLIZUMAB, BEVACIZUMAB,
55
26952197
66 1
Therapy interrupted, Infection,
VENETOCLAX,
56
26952200
65 2
Therapy interrupted, Asthma, Infection, Product use issue,
TEZEPELUMAB-EKKO,
57
26934085
CA
 40
Crohn^s disease, Malaise, Diarrhoea, Nausea, Abscess, Off label use, Therapy interrupted,
INFLIXIMAB-DYYB, INFLIXIMAB-DYYB, SERTRALINE, ARIPIPRAZOLE, PROPRANOLOL HYDROCHLORIDE,
58
26934384
US
 2
Therapy interrupted, Cyst, Pain in extremity, Intercepted product storage error, Device difficult to use, Drug dose omission by device, Arthralgia,
ETANERCEPT, ETANERCEPT,
59
26934420
CO
 66 2
Walking disability, Fall, Bronchitis, Gastritis, Injection site bruising, Sleep apnoea syndrome, Spinal pain, Pain in extremity, Dysstasia, Discouragement, Therapy interrupted, Illness, Ill-defined disorder, Pain, Amnesia, Injection site pain, Injection site haematoma,
ROMOSOZUMAB-AQQG, ROMOSOZUMAB-AQQG, CALCIUM,
60
26934667
CA
 51
Road traffic accident, Product dose omission issue, Therapy interrupted,
ADALIMUMAB-AATY, ADALIMUMAB-AATY,
61
26934740
US
 2
Spinal fracture, Therapy interrupted,
DENOSUMAB,
62
26934802
US
 2
Rheumatoid arthritis, Therapy interrupted,
ETANERCEPT,
63
26934803
AR
 43 1
Myocarditis, Adverse reaction, Rash erythematous, Dermatitis acneiform, Therapy interrupted,
PANITUMUMAB, PANITUMUMAB, OXALIPLATIN, OXALIPLATIN, FLUOROURACIL CREAM, 0.5%, FLUOROURACIL, FLUOROURACIL CREAM, 0.5%, FLUOROURACIL,
64
26935033
US
 85
Hospitalisation, Therapy interrupted, Pain, Pain, Pain, Flank pain, Nausea, Flank pain, Nausea, Vomiting, Incorrect dose administered,
MITOMYCIN, MITOMYCIN, MITOMYCIN,
65
26935386
US
 2
Hereditary angioedema, Hereditary angioedema, Insurance issue, Therapy interrupted,
GARADACIMAB, GARADACIMAB,
66
26935492
AU
 10 1
Bone giant cell tumour benign, Hypercalcaemia, Off label use, Therapy interrupted,
DENOSUMAB,
67
26935802
US
 2
Endometrial cancer, Inappropriate schedule of product administration, Psoriasis, Insurance issue, Therapy interrupted,
BIMEKIZUMAB, BIMEKIZUMAB, BIMEKIZUMAB,
68
26935813
BR
 40 1
Intestinal resection, Adverse reaction, Therapy interrupted, Frequent bowel movements, Diarrhoea, Groin pain, Back pain, Pain in extremity, Acne, Pruritus, Gastrointestinal disorder,
PANITUMUMAB,
69
26935827
US
 54 2
Myocardial infarction, Rheumatoid arthritis, Psoriasis, Depression, Off label use, Illness, Cardiac disorder, Skin laceration, Therapy interrupted, Stress, Product prescribing error, Brain fog,
ETANERCEPT, ETANERCEPT,
70
26935858
US
 2
Psoriatic arthropathy, Maternal exposure during pregnancy, Therapy interrupted, Product availability issue,
CERTOLIZUMAB PEGOL,
71
26935869
US
 1
Psoriatic arthropathy, Therapy interrupted,
ETANERCEPT, PREDNISONE,
72
26936065
US
 59 1
Product distribution issue, Therapy interrupted,
LENALIDOMIDE,
73
26936198
CO
 67 2
Thrombocytopenia, Therapy interrupted,
ROMIPLOSTIM,
74
26936205
US
 2
Meningitis aseptic, Therapy interrupted,
HUMAN IMMUNOGLOBULIN G,
75
26936416
US
 70 1
Psoriatic arthropathy, Therapy interrupted,
ETANERCEPT, ETANERCEPT,
76
26936609
US
 79 2
Therapy interrupted,
LENALIDOMIDE,
77
26936790
US
 2
Psoriatic arthropathy, Rheumatoid arthritis, Product availability issue, Therapy interrupted,
CERTOLIZUMAB PEGOL, CERTOLIZUMAB PEGOL,
78
26937060
CA
 33
Chest pain, Pneumonia, Pyrexia, Cough, Drug effect less than expected, Therapy interrupted, Off label use, Intentional dose omission,
OMALIZUMAB, OMALIZUMAB, OMALIZUMAB, MONTELUKAST,
79
26937212
US
 2
Rheumatoid arthritis, Therapy interrupted,
ETANERCEPT,
80
26937428
US
 76 1
Product packaging quantity issue, Therapy interrupted,
81
26937769
US
 1
Therapy interrupted,
BENRALIZUMAB, BENRALIZUMAB,
82
26938301
US
 75 2
Asthma, Drug interaction, Loss of therapeutic response, Therapy interrupted,
DEXTROMETHORPHAN HYDROBROMIDE, BUPROPION HYDROCHLORIDE, DEXTROMETHORPHAN HYDROBROMIDE, BUPROPION HYDROCHLORIDE, FLUTICASONE PROPIONATE AND SALMETEROL XINAFOATE, DULOXETINE HYDROCHLORIDE, DULOXETINE,
83
26938536
US
 71 2
Hospitalisation, Liver disorder, Condition aggravated, Therapy interrupted, Insurance issue,
RIFAXIMIN,
84
26938563
2
Lethargy, Brain fog, Dyspnoea, Therapy interrupted,
PALBOCICLIB,
85
26938609
US
 2
Therapy interrupted,
BRENSOCATIB, MELATONIN, ACETAMINOPHEN, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE, ACETAMINOPHEN,
86
26938610
US
 2
Condition aggravated, Therapy interrupted,
BRENSOCATIB,
87
26938830
US
 2
Therapy interrupted, Fatigue, Dizziness, Vertigo,
ABALOPARATIDE,
88
26938844
US
 63 2
Dizziness, Headache, Fatigue, Intentional product misuse, Therapy interrupted, Product quality issue, Product dose omission issue,
ABALOPARATIDE, ABALOPARATIDE, ABALOPARATIDE, ZINC OXIDE, PACIFICA ULTRA CC CREAM RADIANT FOUNDATION SPF 30 WARM/LIGHT, ZINC OXIDE OINTMENT, PACIFICA ULTRA CC CREAM RADIANT FOUNDATION SPF 30 WARM/TAN, ZINC OXIDE 20%, SKIN PROTECTANT, PACIFICA ULTRA CC CREAM RADIANT FOUNDATION SPF 30 NATURAL/MEDIUM, PACIFICA ULTRA CC CREAM RADIANT FOUNDATION SPF 30 COOL/DEEP, MINERAL SUNSHIELD UNIVERSAL TINT BROAD SPECTRUM SPF 30 SUNSCREEN, MAGNESIUM OXIDE, CALCIUM, ERGOCALCIFEROL, FISH OIL, VITAMIN C, NETARSUDIL, BIMATOPROST, TIMOLOL MALEATE, TIMOLOL MALEATE OPHTHALMIC,
89
26938875
US
 73 1
Product administered at inappropriate site, Product use complaint, Therapy interrupted,
ABALOPARATIDE, ABALOPARATIDE, GABAPENTIN, LISINOPRIL, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, TERIPARATIDE,
90
26938879
US
 2
Injection site bruising, Therapy interrupted, Product availability issue,
ABALOPARATIDE,
91
26938904
US
 1
Therapy interrupted, Injection site bruising,
ABALOPARATIDE,
92
26938905
US
 70 2
Dizziness, Therapy interrupted, Off label use,
ABALOPARATIDE, ABALOPARATIDE, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, TOCILIZUMAB, DULOXETINE HYDROCHLORIDE, DULOXETINE, TOLTERODINE,
93
26938952
US
 72 2
Injection site bruising, Product dose omission issue, Therapeutic product effect incomplete, Therapy interrupted, Product use complaint, Device malfunction, Product use issue, Device defective,
ABALOPARATIDE,
94
26938958
US
 79 1
Therapy interrupted, Intentional dose omission, Product use complaint, Needle issue, Needle issue, Drug dose omission by device, Drug ineffective,
ABALOPARATIDE, ABALOPARATIDE,
95
26938976
US
 2
Dizziness, Malaise, Therapy interrupted,
ABALOPARATIDE, ABALOPARATIDE,
96
26939041
US
 69 2
Therapy interrupted, Incorrect product administration duration, Product dose omission issue,
ABALOPARATIDE, TIRZEPATIDE,
97
26939165
US
 2
Therapy interrupted, Drug dose omission by device, Device failure, Device issue, Device failure, Product dose omission issue,
ABALOPARATIDE, ABALOPARATIDE, PIROXICAM,
98
26939187
US
 2
Influenza, Spinal pain, Therapy interrupted,
ABALOPARATIDE, ABALOPARATIDE,
99
26939721
US
 72 2
Headache, Therapy interrupted, Intentional product misuse,
ABALOPARATIDE, ABALOPARATIDE,
100
26943067
65 2
Therapy interrupted, Atrial fibrillation, Sepsis, Hepatic enzyme increased,
AVACOPAN,

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last_updated

2026-07-30

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