Drug:
Reaction: THERAPY INTERRUPTED
20260101 - 20261231
No. 1 - 100
| No. | safetyreportid |
occurcountry |
patientonsetage |
patientsex 1:M 2:F |
|---|---|---|---|---|
Adverse reaction |
||||
Drug (openfda.generic_name, medicinalproduct) |
||||
| 1 | 26555384 |
US |
2 | |
Psoriatic arthropathy, Therapy interrupted, |
||||
APREMILAST, |
||||
| 2 | 26555516 |
63 | ||
Product distribution issue, Therapy interrupted, |
||||
CERTOLIZUMAB PEGOL, |
||||
| 3 | 26555567 |
US |
2 | |
Feeling abnormal, Arthropathy, Therapy interrupted, Off label use, |
||||
ETANERCEPT, ETANERCEPT, |
||||
| 4 | 26555610 |
|||
Therapy interrupted, |
||||
BIMEKIZUMAB, |
||||
| 5 | 26555990 |
US |
2 | |
Device failure, Device delivery system issue, Accidental exposure to product, Exposure via skin contact, Therapy interrupted, |
||||
ABATACEPT, |
||||
| 6 | 26556001 |
US |
2 | |
Therapy interrupted, Anxiety, |
||||
DENOSUMAB, |
||||
| 7 | 26556035 |
US |
2 | |
Therapy interrupted, Psoriasis, |
||||
ETANERCEPT, ETANERCEPT, |
||||
| 8 | 26556055 |
US |
66 | 1 |
Therapy interrupted, Pain, |
||||
ETANERCEPT, |
||||
| 9 | 26556074 |
AR |
66 | 2 |
Anal incontinence, Rectal haemorrhage, Hepatitis, Skin burning sensation, Swollen tongue, Mouth swelling, Eating disorder, Pain, Rash, Pruritus, Exfoliative rash, Decreased immune responsiveness, Colostomy bag user, Acne pustular, Ill-defined disorder, Rash macular, Erythema, Blister, Malaise, Discomfort, Skin haemorrhage, Dysarthria, Drug ineffective, Dry skin, Off label use, Drug hypersensitivity, Flatulence, Blood test abnormal, Magnetic resonance imaging abnormal, Therapy interrupted, Musculoskeletal pain, |
||||
PANITUMUMAB, PANITUMUMAB, PANITUMUMAB, PANITUMUMAB, |
||||
| 10 | 26556099 |
US |
26 | |
Haemorrhage, Condition aggravated, Therapy interrupted, |
||||
INFLIXIMAB-DYYB, |
||||
| 11 | 26556233 |
US |
69 | 1 |
Psoriatic arthropathy, Therapy interrupted, |
||||
ETANERCEPT, |
||||
| 12 | 26556513 |
US |
60 | 2 |
Therapy interrupted, Metapneumovirus infection, Oxygen saturation decreased, Speech disorder, Illness, |
||||
| 13 | 26557199 |
US |
1 | |
Hallucination, Therapy interrupted, |
||||
PIMAVANSERIN TARTRATE, FLUOXETINE HYDROCHLORIDE, FLUOXETINE, FUROSEMIDE, GARLIC, LEVODOPA, POLYETHYLENE GLYCOL 3350, POTASSIUM CHLORIDE, POTASSIUM CHLORIDE EXTENDED-RELEASE, POTASSIUM CHLORIDE, DEXTROSE MONOHYDRATE, POTASSIUM CHLORIDE ORAL, RIVASTIGMINE, RIVASTIGMINE, TERBINAFINE HYDROCHLORIDE, TERBINAFINE TABLETS 250 MG, TERBINAFINE HYDROCHLORIDE, TERBINAFINE, FOSCARBIDOPA/FOSLEVODOPA, INCOBOTULINUMTOXINA, |
||||
| 14 | 26557286 |
73 | ||
Blood pressure increased, Inappropriate schedule of product administration, Product use issue, Therapy interrupted, |
||||
LACOSAMIDE, |
||||
| 15 | 26558418 |
US |
1 | |
Hallucination, Condition aggravated, Product distribution issue, Therapy interrupted, |
||||
PIMAVANSERIN TARTRATE, PIMAVANSERIN TARTRATE, |
||||
| 16 | 26558617 |
US |
60 | 2 |
Rheumatoid arthritis, Joint swelling, Abdominal discomfort, Arthralgia, Insurance issue, Therapy interrupted, |
||||
ABATACEPT, PREDNISONE, |
||||
| 17 | 26558801 |
US |
23 | |
Therapy interrupted, |
||||
ISOTRETINOIN, |
||||
| 18 | 26558802 |
US |
15 | |
Therapy interrupted, |
||||
ISOTRETINOIN, |
||||
| 19 | 26558852 |
US |
20 | |
Therapy interrupted, |
||||
ISOTRETINOIN, ISOTRETINOIN, |
||||
| 20 | 26559685 |
US |
2 | |
Ill-defined disorder, Therapy interrupted, |
||||
RIFAXIMIN, |
||||
| 21 | 26559979 |
US |
64 | |
Gingivitis, Illness, Therapy interrupted, |
||||
ANAKINRA, |
||||
| 22 | 26560714 |
US |
2 | |
Product packaging issue, Therapy interrupted, |
||||
| 23 | 26560842 |
US |
72 | 1 |
Ammonia increased, Hepatic cirrhosis, Condition aggravated, Hospitalisation, Confusional state, Therapy interrupted, Product use issue, |
||||
RIFAXIMIN, RIFAXIMIN, |
||||
| 24 | 26560910 |
40 | ||
Hospitalisation, Kidney infection, Treatment noncompliance, Insurance issue, Therapy interrupted, |
||||
CERTOLIZUMAB PEGOL, |
||||
| 25 | 26561605 |
US |
1 | |
Rheumatoid arthritis, Therapy interrupted, |
||||
ETANERCEPT, |
||||
| 26 | 26563882 |
61 | 2 | |
Arthropod bite, Cellulitis, Therapy interrupted, |
||||
SOTATERCEPT-CSRK, TREPROSTINIL, |
||||
| 27 | 26563888 |
2 | ||
Therapy interrupted, Urinary tract infection, |
||||
SOTATERCEPT-CSRK, |
||||
| 28 | 26563889 |
2 | ||
Therapy interrupted, Urinary tract infection, |
||||
AMBRISENTAN, SOTATERCEPT-CSRK, |
||||
| 29 | 26563900 |
2 | ||
Therapy interrupted, Cholecystitis infective, |
||||
SOTATERCEPT-CSRK, RIOCIGUAT, TREPROSTINIL, |
||||
| 30 | 26565738 |
2 | ||
Cardiac disorder, Therapy interrupted, Hospitalisation, |
||||
EVOLOCUMAB, CARVEDILOL, DONEPEZIL HYDROCHLORIDE, ICOSAPENT ETHYL, MAGNESIUM, SEMAGLUTIDE, ORAL SEMAGLUTIDE, PANTOPRAZOLE, EVOLOCUMAB, ERGOCALCIFEROL, |
||||
| 31 | 26565741 |
1 | ||
Hospitalisation, Therapy interrupted, |
||||
TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, ALLOPURINOL, AMLODIPINE, TACROLIMUS, |
||||
| 32 | 26569635 |
53 | 2 | |
Therapy interrupted, Urinary tract infection, |
||||
ETANERCEPT, |
||||
| 33 | 26569892 |
2 | ||
Blood glucose increased, Dry mouth, Fatigue, Decreased appetite, Vomiting, Nausea, Vision blurred, Diarrhoea, Therapy interrupted, |
||||
FULVESTRANT, CAPIVASERTIB, |
||||
| 34 | 26569960 |
55 | 2 | |
Therapy interrupted, |
||||
AVACOPAN, AVACOPAN, |
||||
| 35 | 26569966 |
2 | ||
Knee arthroplasty, Therapy interrupted, |
||||
LENALIDOMIDE, |
||||
| 36 | 26570022 |
1 | ||
Therapy interrupted, Pneumonia, Thrombosis, Pulmonary embolism, |
||||
LENALIDOMIDE, |
||||
| 37 | 26570040 |
1 | ||
Therapy interrupted, Diverticulitis, Loss of personal independence in daily activities, |
||||
TOFACITINIB, HYDROXYCHLOROQUINE, LOSARTAN POTASSIUM, LOSARTAN, METHYLPREDNISOLONE, |
||||
| 38 | 26570057 |
2 | ||
Hip surgery, Therapy interrupted, |
||||
PALBOCICLIB, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ALLOPURINOL, ANASTROZOLE, ANASTROZOLE TABLETS, AMLODIPINE BESYLATE AND ATORVASTATIN CALCIUM, AMLODIPINE AND ATORVASTATIN, LORATADINE, LORATADINE TABLET, DOCUSATE SODIUM, DOCUSATE SODIUM - SENNOSIDES, |
||||
| 39 | 26570287 |
53 | 2 | |
Product dose omission in error, Memory impairment, Therapy interrupted, |
||||
AVACOPAN, |
||||
| 40 | 26550239 |
US |
61 | 2 |
Rheumatoid arthritis, Therapy interrupted, |
||||
ETANERCEPT, |
||||
| 41 | 26550443 |
US |
2 | |
Psoriatic arthropathy, Alopecia, Psoriasis, Therapy interrupted, |
||||
APREMILAST, |
||||
| 42 | 26550554 |
US |
74 | 1 |
Product supply issue, Therapy interrupted, |
||||
LENALIDOMIDE, |
||||
| 43 | 26550591 |
US |
72 | |
Incorrect dose administered by device, Device difficult to use, Inappropriate schedule of product administration, Therapy interrupted, |
||||
EVOLOCUMAB, EVOLOCUMAB, |
||||
| 44 | 26550709 |
CA |
43 | 1 |
Arthralgia, Blood glucose increased, Cellulitis, Headache, Hypersensitivity, Injection site pain, Joint dislocation, Psoriasis, Therapy interrupted, Drug ineffective, Product distribution issue, |
||||
METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, BRODALUMAB, BRODALUMAB, BRODALUMAB, |
||||
| 45 | 26551157 |
US |
68 | 1 |
Intervertebral disc protrusion, Therapy interrupted, |
||||
DILTIAZEM HYDROCHLORIDE, DILTIAZEM HYDROCHLORIDE, |
||||
| 46 | 26551259 |
|||
Oesophagitis, Rash, Impaired quality of life, Therapy interrupted, |
||||
BIMEKIZUMAB, DUPILUMAB, EPINEPHRINE, ADRENALINUM, PANTOPRAZOLE, |
||||
| 47 | 26551541 |
US |
1 | |
Therapy interrupted, Psoriasis, |
||||
ETANERCEPT, ETANERCEPT, ETANERCEPT, |
||||
| 48 | 26551644 |
US |
82 | |
Therapy interrupted, Urethral stenosis, |
||||
MITOMYCIN, MITOMYCIN, MITOMYCIN, MITOMYCIN, |
||||
| 49 | 26551924 |
US |
2 | |
Rheumatoid arthritis, Therapy interrupted, |
||||
ETANERCEPT, |
||||
| 50 | 26552399 |
1 | ||
Therapy interrupted, |
||||
LENALIDOMIDE, |
||||
| 51 | 26552597 |
US |
2 | |
Arthritis, Therapy interrupted, |
||||
ETANERCEPT, ETANERCEPT, |
||||
| 52 | 26552635 |
US |
69 | 2 |
Unevaluable event, Pain, Mobility decreased, Therapy interrupted, Dysstasia, |
||||
ETANERCEPT, |
||||
| 53 | 26552792 |
1 | ||
Urticaria, Loss of personal independence in daily activities, Therapy interrupted, |
||||
TOBRAMYCIN, VANZACAFTOR, TEZACAFTOR, AND DEUTIVACAFTOR, VANCOMYCIN HYDROCHLORIDE, VANCOMYCIN, |
||||
| 54 | 26552972 |
68 | 2 | |
Cerebrovascular accident, Therapy interrupted, |
||||
LENALIDOMIDE, DEXAMETHASONE, DEXAMETHASONE 1.5 MG, |
||||
| 55 | 26553115 |
US |
2 | |
Psoriatic arthropathy, Psoriasis, Therapy interrupted, |
||||
ETANERCEPT, ETANERCEPT, |
||||
| 56 | 26553131 |
1 | ||
Fall, Contusion, Therapy interrupted, Mobility decreased, Depression, Fatigue, Multiple sclerosis relapse, |
||||
INTERFERON BETA-1A, DEXTROAMPHETAMINE SULFATE, DEXTROAMPHETAMINE SACCHARATE, AMPHETAMINE SULFATE AND AMPHETAMINE ASPARTATE, ALBUTEROL SULFATE, ALBUTEROL, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, LORAZEPAM, BUMETANIDE, FISH OIL, OXYCODONE HYDROCHLORIDE AND ACETAMINOPHEN, |
||||
| 57 | 26553470 |
1 | ||
Therapy interrupted, Nonspecific reaction, |
||||
PEGVISOMANT, PEGVISOMANT, RABEPRAZOLE SODIUM, FLUTICASONE PROPIONATE, ACETAMINOPHEN, CHLORPHENIRAMINE MALEATE, PHENYLEPHRINE HCL, LINACLOTIDE, MECLIZINE HCL 12.5 MG, MECLIZINE HCL 25 MG, MECLIZINE HYDROCHLORIDE, MECLIZINE, MECLIZINE HCL 25MG, MECLIZINE HCL 12.5MG, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, METOPROLOL TARTRATE, METOROPROLOL TARTRATE, METOPROLOL, |
||||
| 58 | 26553549 |
66 | ||
Myasthenia gravis, Insurance issue, Therapy interrupted, |
||||
ZILUCOPLAN, |
||||
| 59 | 26553568 |
US |
2 | |
Type 1 diabetes mellitus, Migraine, Therapy interrupted, Ill-defined disorder, |
||||
ERENUMAB-AOOE, |
||||
| 60 | 26553862 |
72 | ||
Dyspnoea, Rash, Tracheal obstruction, Therapy interrupted, Product dispensing issue, Off label use, |
||||
CERTOLIZUMAB PEGOL, CERTOLIZUMAB PEGOL, CERTOLIZUMAB PEGOL, |
||||
| 61 | 26553873 |
CA |
80 | 2 |
Death, Renal impairment, Renal impairment, Product dose omission issue, Wheelchair user, General physical health deterioration, Therapy interrupted, |
||||
| 62 | 26554099 |
US |
2 | |
Oral pain, Lip pain, Hypoaesthesia oral, Oral discomfort, Oral hyperaesthesia, Tongue discomfort, Tongue discolouration, Glossodynia, Product use issue, Inappropriate schedule of product administration, Drug ineffective, Therapy interrupted, |
||||
ENSIFENTRINE, ENSIFENTRINE, ENSIFENTRINE, TIOTROPIUM BROMIDE AND OLODATEROL, LEVALBUTEROL, LEVALBUTEROL HYDROCHLORIDE, AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, |
||||
| 63 | 26554232 |
44 | ||
Rheumatoid arthritis, Therapy interrupted, |
||||
CERTOLIZUMAB PEGOL, |
||||
| 64 | 26554281 |
US |
70 | 2 |
Application site pain, Application site erythema, Device issue, Therapy interrupted, |
||||
EFINACONAZOLE, |
||||
| 65 | 26555060 |
US |
76 | 2 |
Psoriatic arthropathy, Therapy interrupted, |
||||
ETANERCEPT, |
||||
| 66 | 26555099 |
EU |
2 | |
Compression fracture, Therapy interrupted, |
||||
DENOSUMAB, |
||||
| 67 | 26555108 |
US |
83 | 2 |
Psoriatic arthropathy, Therapy interrupted, |
||||
ETANERCEPT, |
||||
| 68 | 26555126 |
AR |
21 | 2 |
Hospitalisation, Product availability issue, Therapy interrupted, Off label use, |
||||
INFLIXIMAB, |
||||
| 69 | 26555189 |
US |
84 | 2 |
Syncope, Hospitalisation, Therapy interrupted, |
||||
CAPIVASERTIB, |
||||
| 70 | 26555275 |
AR |
68 | 2 |
Carcinoembryonic antigen increased, Hypertransaminasaemia, Rash, Dry skin, Therapy interrupted, Acne, Pruritus, Blood magnesium decreased, Fatigue, Insomnia, |
||||
PANITUMUMAB, SOTORASIB, SOTORASIB, |
||||
| 71 | 26557650 |
24 | 2 | |
Sepsis, Clostridium difficile infection, Urinary tract infection, Therapy interrupted, |
||||
TENAPANOR HYDROCHLORIDE, TENAPANOR HYDROCHLORIDE, |
||||
| 72 | 26557751 |
84 | 1 | |
Surgery, Therapy interrupted, |
||||
ETANERCEPT, |
||||
| 73 | 26557927 |
51 | 2 | |
Pneumonia, COVID-19, Pain, Therapy interrupted, Insomnia, Depression, |
||||
NILOTINIB, |
||||
| 74 | 26558002 |
75 | 2 | |
Multiple sclerosis relapse, Therapy interrupted, |
||||
GLATIRAMER ACETATE, |
||||
| 75 | 26558003 |
2 | ||
Therapy interrupted, |
||||
TAFAMIDIS, FUROSEMIDE, METOPROLOL TARTRATE, METOROPROLOL TARTRATE, METOPROLOL, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, WARFARIN, |
||||
| 76 | 26558218 |
68 | 2 | |
Weight increased, Hepatic steatosis, Blood glucose increased, Hypertension, Neuropathy peripheral, Arthralgia, Cough, Therapy interrupted, |
||||
ALECTINIB HYDROCHLORIDE, |
||||
| 77 | 26558239 |
2 | ||
Surgery, Therapy interrupted, Depression, |
||||
SECUKINUMAB, AMOXICILLIN, FOLIC ACID, METHOTREXATE, METHOTREXATE SODIUM, |
||||
| 78 | 26558330 |
55 | 1 | |
Cerebrovascular accident, Off label use, Therapy interrupted, |
||||
MAVACAMTEN, |
||||
| 79 | 26558341 |
68 | 2 | |
Therapy interrupted, |
||||
MAVACAMTEN, |
||||
| 80 | 26558435 |
1 | ||
Pneumonia, Therapy interrupted, |
||||
TAFAMIDIS, |
||||
| 81 | 26558470 |
2 | ||
Therapy interrupted, |
||||
LENALIDOMIDE, LENALIDOMIDE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, CEFTRIAXONE SODIUM, BACLOFEN, EPINEPHRINE, FEBUXOSTAT, FEBUXOSTAT TABLETS 40 MG, FEBUXOSTAT TABLETS 80 MG, FUROSEMIDE, |
||||
| 82 | 26558471 |
2 | ||
Therapy interrupted, |
||||
VIGABATRIN, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), CANNABIDIOL, ESOMEPRAZOLE MAGNESIUM, CLOBAZAM, |
||||
| 83 | 26558638 |
79 | 2 | |
Therapy interrupted, |
||||
DROXIDOPA, |
||||
| 84 | 26558641 |
85 | 1 | |
Therapy interrupted, Respiratory syncytial virus test positive, Cellulitis, Decreased appetite, Recalled product, |
||||
ETANERCEPT, |
||||
| 85 | 26558661 |
24 | 1 | |
Pneumonia, Therapy interrupted, |
||||
RISANKIZUMAB-RZAA, |
||||
| 86 | 26558690 |
74 | 1 | |
Surgery, Therapy interrupted, |
||||
LENALIDOMIDE, |
||||
| 87 | 26558692 |
1 | ||
Pyrexia, Therapy interrupted, |
||||
POMALIDOMIDE, ACYCLOVIR, OLMESARTAN MEDOXOMIL, BENZONATATE, CALCIUM, DEXAMETHASONE, DEXAMETHASONE 1.5 MG, |
||||
| 88 | 26558697 |
2 | ||
Pain, Loss of personal independence in daily activities, Therapy interrupted, |
||||
ADALIMUMAB-RYVK, BIOTIN, CALCIUM, ETANERCEPT, FISH OIL, GABAPENTIN, |
||||
| 89 | 26558704 |
62 | 2 | |
Therapy interrupted, Hospitalisation, |
||||
ABALOPARATIDE, |
||||
| 90 | 26558859 |
67 | 2 | |
Myocardial infarction, Orthostatic hypotension, Palpitations, Therapy interrupted, |
||||
TERIPARATIDE, |
||||
| 91 | 26558896 |
1 | ||
Hospitalisation, Therapy interrupted, |
||||
CAPECITABINE, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, CAPECITABINE, BEVACIZUMAB-AWWB, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, |
||||
| 92 | 26558900 |
80 | 2 | |
Hospitalisation, Therapy interrupted, |
||||
VENETOCLAX, |
||||
| 93 | 26558938 |
77 | 2 | |
Influenza, Therapy interrupted, |
||||
ABALOPARATIDE, |
||||
| 94 | 26558974 |
71 | 2 | |
Femur fracture, Therapy interrupted, |
||||
ETANERCEPT, |
||||
| 95 | 26559028 |
49 | 1 | |
Cerebrovascular accident, Therapy interrupted, |
||||
APREMILAST, |
||||
| 96 | 26559031 |
66 | 2 | |
Pneumonia, Therapy interrupted, |
||||
ABALOPARATIDE, |
||||
| 97 | 26559044 |
1 | ||
Urinary tract infection, Sepsis, Therapy interrupted, |
||||
LENALIDOMIDE, DARATUMUMAB, FEXOFENADINE HYDROCHLORIDE, FEXOFENADINE HYDROCHLORIDE ORAL, FEXOFENADINE HCL, LENALIDOMIDE, MELATONIN, |
||||
| 98 | 26559115 |
2 | ||
Hospitalisation, Therapy interrupted, |
||||
LORLATINIB, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, CALCIUM, HYDROCHLOROTHIAZIDE, LORLATINIB, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, |
||||
| 99 | 26559118 |
60 | 2 | |
Cerebrovascular accident, Therapy interrupted, |
||||
ETANERCEPT, |
||||
| 100 | 26559257 |
2 | ||
Infection, Therapy interrupted, |
||||
LENALIDOMIDE, BIOTIN, CETIRIZINE HCL, CETIRIZINE, FISH OIL, FLUOXETINE HYDROCHLORIDE, FLUOXETINE, FUROSEMIDE, GABAPENTIN, IRON, DIPHENOXYLATE HYDROCHLORIDE AND ATROPINE SULFATE, |
||||
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Do not rely on openFDA to make decisions regarding medical care. While we make every effort to ensure that data is accurate, you should assume all results are unvalidated. We may limit or otherwise restrict your access to the API in line with our Terms of Service.
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last_updated
2026-04-28