Drug Search by Year (Detail)

26921447

US

Parvovirus B19 infection, Acute kidney injury, Drug ineffective, Anaemia, Respiratory failure,

PREDNISONE, HUMAN IMMUNOGLOBULIN G, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES,

26921544

US

Chronic kidney disease, Type 2 diabetes mellitus, Renal cancer, Aortic arteriosclerosis, Computerised tomogram heart, Diabetic nephropathy, Cataract diabetic, Chronic left ventricular failure, Peripheral arterial occlusive disease, Anaemia, Essential hypertension, Anxiety, Lipoprotein (a) increased, Hypertriglyceridaemia, Back pain, Neuralgia, Arthralgia, Fatigue, Dyspnoea, Exercise lack of, Sinus tachycardia, Obesity, Depression,

EVOLOCUMAB, EVOLOCUMAB,

26921660

EU

Cardio-respiratory arrest, Malignant neoplasm oligoprogression, Metastases to bone, Pneumonia, Metastases to liver, Anaemia, Disease progression, Haemoptysis, Weight decreased, Bone disorder, Upper respiratory tract infection,

BEVACIZUMAB, ATEZOLIZUMAB, PACLITAXEL, PACLITAXEL (AIBUMIN-BOUND), CARBOPLATIN,

26921734

US

Anti-neutrophil cytoplasmic antibody positive vasculitis, Skin ulcer, Cellulitis, Anaemia, Limb injury, Renal necrosis, Glomerulonephritis,

ROSUVASTATIN, APIXABAN, CEPHALEXIN,

26921751

EU

Aorto-oesophageal fistula, Drug ineffective, Tissue injury, Shock haemorrhagic, Pneumonia, Anaemia,

NIVOLUMAB, CABOZANTINIB, ATEZOLIZUMAB,

26921835

EU

Anaemia, Thrombocytopenia, Neutropenia, Neuropathy peripheral, Atrial fibrillation,

DEXAMETHASONE, DEXAMETHASONE 1.5 MG, ISATUXIMAB, BORTEZOMIB, LENALIDOMIDE,

26921840

EU

Pyrexia, Anaemia, Hyperglycaemia,

LUTETIUM LU 177 VIPIVOTIDE TETRAXETAN, LUTETIUM LU 177 VIPIVOTIDE TETRAXETAN,

26921957

US

Anaemia,

26921987

EU

Bacterial infection, Cytokine release syndrome, Neutropenia, Secondary immunodeficiency, Infection, Thrombocytopenia, Febrile neutropenia, Anaemia, Off label use,

26922081

GB

Anaemia,

26922243

CA

Anaemia, Headache, Malaise, Pneumonia, Cough, Chronic sinusitis, Lung disorder,

METHOTREXATE, METHOTREXATE SODIUM, RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, RITUXIMAB, DIPHENHYDRAMINE, DIPHENHYDRAMINE HYDROCHLORIDE, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, METHYLPREDNISOLONE,

26922254

EU

Disease progression, Anaemia, Drug ineffective,

DASATINIB, ASCIMINIB, NILOTINIB,

26922374

EU

Toxic epidermal necrolysis, Neutropenia, Syncope, Acute kidney injury, Rhabdomyolysis, Thrombocytopenia, Coma, Leukopenia, Hypokalaemia, Fall, Escherichia bacteraemia, Nausea, Stomatitis, Fatigue, Flushing, Decreased appetite, Weight decreased, Vomiting, Fatigue, General physical health deterioration, Hyponatraemia, Metabolic acidosis, Respiratory alkalosis, Hypotension, Anaemia, Asthenia,

CAPECITABINE, CAPECITABINE, ALPRAZOLAM, PAROXETINE, PAROXETINE HYDROCHLORIDE, PAROXETINE HYDROCHLORIDE HEMIHYDRATE,

26922474

US

Diverticulitis, Anaemia,

RISANKIZUMAB-RZAA,

26922825

CN

Anaemia, Nausea, Fatigue, Leukopenia, Neutropenia, Constipation, Decreased appetite, Transaminases increased, Hypothyroidism, Pneumonitis, Hypophysitis, Myocarditis, Adrenal insufficiency, Type 1 diabetes mellitus, Neuropathy peripheral, Hyperplasia, Rash,

ATEZOLIZUMAB, PEMBROLIZUMAB, NIVOLUMAB, PENPULIMAB, PEMETREXED, PEMETREXED DISODIUM, CISPLATIN, CARBOPLATIN,

26922829

Acute kidney injury, Hyperbilirubinaemia, Hyperkalaemia, Haemolysis, Anaemia, Metabolic acidosis, Methaemoglobinaemia, Contraindicated product administered,

26922932

US

Anaemia,

ABEMACICLIB,

26923066

US

Injection site pain, Anaemia, Pruritus,

DUPILUMAB,

26923221

JP

Leukopenia, Neutropenia, Febrile neutropenia, Thrombocytopenia, Anaemia, Aspartate aminotransferase increased, Alanine aminotransferase increased, Hyponatraemia, Hyperkalaemia, Hypokalaemia, Blood creatinine increased, Hypoalbuminaemia, Decreased appetite, Nausea, Vomiting, Dysgeusia, Fatigue, Malaise, Rash, Constipation, Diarrhoea,

ATEZOLIZUMAB, CARBOPLATIN, ETOPOSIDE,

26923300

AE

Chronic kidney disease, Osteonecrosis, Anaemia, Arteriosclerosis,

FULVESTRANT, FULVESTRANT, ERGOCALCIFEROL, DENOSUMAB, PALBOCICLIB,

26923605

US

Colitis, Acute kidney injury, Dyspnoea, Dyspnoea, Platelet count decreased, Pleural effusion, Ileus, Anaemia, Generalised oedema,

PEMBROLIZUMAB, PEMBROLIZUMAB, PEMBROLIZUMAB, PEMBROLIZUMAB, PEMETREXED, PEMETREXED DISODIUM, CARBOPLATIN, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, DIAZEPAM, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, DOCUSATE SODIUM, DOCUSATE SODIUM - SENNOSIDES, SENNOSIDES 8.6 MG TABLETS, SENNOSIDES, SENNA LEAF, SENNA, ALPRAZOLAM, ERGOCALCIFEROL, DEXAMETHASONE, DEXAMETHASONE 1.5 MG, FOLIC ACID, ALPRAZOLAM, FUROSEMIDE, METOLAZONE,

26923979

GB

Anaemia, Vascular stent thrombosis, Platelet aggregation increased, Drug ineffective,

CLOPIDOGREL, CLOPIDOGREL BISULFATE, CLOPIDOGREL, CLOPIDOGREL BISULFATE, IBRUTINIB, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG,

26924386

RU

Hepatotoxicity, Anaemia,

TALAZOPARIB,

26924527

US

Hypoxia, Pneumonia, Hyperglycaemia, Peripheral sensory neuropathy, Dyspnoea, Lymphocyte count decreased, Urinary tract infection, Gastrointestinal disorder, Fatigue, Diarrhoea, Platelet count decreased, Muscular weakness, Cough, Upper respiratory tract infection, Infestation, Anaemia, White blood cell count decreased, Neutrophil count decreased, Nausea, Constipation, Infection, Cognitive disorder, Oedema peripheral, Rash maculo-papular, Peripheral motor neuropathy, Vomiting, Insomnia, Gastrooesophageal reflux disease, Blood creatinine increased, Intentional product use issue,

DARATUMUMAB, IXAZOMIB, CYCLOPHOSPHAMIDE FOR INJECTION, CYCLOPHOSPHAMIDE, CYCLOPHOSPHAMIDE INJECTION, SOLUTION, DEXAMETHASONE, DEXAMETHASONE 1.5 MG,

26924630

GB

Anaemia,

CLOZAPINE,

26924726

US

Liver function test increased, Blood potassium abnormal, Anaemia, Hepatic function abnormal,

GUSELKUMAB, AZATHIOPRINE, PREDNISONE,

26924976

JP

Febrile neutropenia, Pneumonia, Hypothyroidism, Urinary retention, Hypersensitivity, Rash, Anaemia, Constipation,

DURVALUMAB, OLAPARIB, PACLITAXEL, PACLITAXEL (AIBUMIN-BOUND), CARBOPLATIN,

26925143

US

Full blood count decreased, Anaemia, Neutropenia,

LENALIDOMIDE, LENALIDOMIDE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, DARATUMUMAB, DEXAMETHASONE, DEXAMETHASONE 1.5 MG, EPINEPHRINE, ADRENALINUM, GABAPENTIN, HYDROCORTISONE SODIUM SUCCINATE, ACETAMINOPHEN, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE, ACETAMINOPHEN, VALACYCLOVIR HYDROCHLORIDE,

26925189

US

Anaemia, Infection,

ELRANATAMAB-BCMM,

26925254

US

Anaemia, Red blood cell sedimentation rate increased, Oedema peripheral, Weight increased, Retinal vein occlusion, Osteopenia, Renal impairment, Stress fracture, Neutropenia, Sternal fracture, C-reactive protein increased, Uveitis, Rebound effect, Off label use, Vein rupture, Spinal fracture, Serum ferritin increased,

PREDNISONE, PREDNISONE, PREDNISONE, PREDNISONE, PREDNISONE, TOCILIZUMAB, AZACITIDINE, AZACITIDINE FOR, VORICONAZOLE, VORICONAZOLE INJECTION, ACYCLOVIR, ATOVAQUONE, ATOVAQUONE ORAL SUSPENSION,

26925426

BR

Plasma cell myeloma, Drug ineffective, Pain, Anaemia,

BORTEZOMIB, DEXAMETHASONE, DEXAMETHASONE 1.5 MG, LENALIDOMIDE,

26925537

Pulmonary oedema, Malignant neoplasm progression, Interstitial lung disease, Anaemia, Aspartate aminotransferase increased, Alanine aminotransferase increased, SARS-CoV-2 test positive,

ABEMACICLIB, ANASTROZOLE, ANASTROZOLE TABLETS, DENOSUMAB,

26925565

EU

Loss of consciousness, Anaemia, Thrombocytopenia,

DOSTARLIMAB,

26925974

JP

Oesophageal candidiasis, Candida infection, Arrhythmia, Folliculitis, Eczema, Anaemia, Ocular hyperaemia, Injection site reaction, Dyshidrotic eczema,

BIMEKIZUMAB, BIMEKIZUMAB, BIMEKIZUMAB,

26926222

US

Post procedural complication, Anaemia,

DUPILUMAB,

26926332

EU

Thrombocytopenia, Neutropenia, Anaemia, Off label use,

RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, HYDROXYUREA,

26926455

CA

Nephrolithiasis, Anaemia, Blood phosphorus decreased,

EPTINEZUMAB-JJMR, TOPIRAMATE, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, HYDROCORTISONE, MAGNESIUM, CALCIUM, FOLIC ACID,

26929161

Stem cell transplant, Anaemia, Vitamin B12 decreased, Bone pain,

LENALIDOMIDE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, FOLIC ACID, GABAPENTIN, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, OXYCODONE, PANTOPRAZOLE, VALSARTAN, VALSARTAN ORAL,

26930300

Anaemia, Oedema, Gait disturbance, Exercise tolerance decreased, Vomiting, Muscular weakness,

ADALIMUMAB,

26915162

EU

Clostridium difficile colitis, Colitis, Hepatitis cholestatic, Thrombocytopenia, Pancytopenia, Clostridium difficile colitis, Anaemia, Dysphagia, Hypergammaglobulinaemia, Epstein-Barr virus infection, Urinary tract infection bacterial,

OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, PIPERACILLIN SODIUM,TAZOBACTAM SODIUM, DAPTOMYCIN, CARBAMAZEPINE, LEVETIRACETAM, FOLIC ACID, CALCIFEDIOL, VALPROIC ACID,

26915180

EU

Leukopenia, Thrombocytopenia, Thrombosis, Anaemia, Body temperature increased, General physical health deterioration,

CARBOPLATIN, PACLITAXEL, PACLITAXEL (AIBUMIN-BOUND),

26915268

Circulatory collapse, Anaphylactic reaction, Angioedema, Intentional product misuse, Anaemia,

DICLOFENAC, DICLOFENAC SODIUM, TIZANIDINE, DEXAMETHASONE, DEXAMETHASONE 1.5 MG, DEXLANSOPRAZOLE, METHOTREXATE, METHOTREXATE SODIUM, HYDROXYCHLOROQUINE, SULFASALAZINE, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, FOLIC ACID, ESOMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM, CARBAMAZEPINE, LACOSAMIDE, AMLODIPINE,

26915497

EU

Pancytopenia, Feeling hot, Hot flush, Poor quality sleep, Flatulence, Leukocytosis, Thrombocytopenia, Musculoskeletal stiffness, Weight increased, Increased appetite, Decreased appetite, Pain in extremity, Myalgia, Anaemia, Fatigue, Diarrhoea, Dizziness, Headache, Nausea, Therapeutic product effect incomplete, Cytogenetic analysis abnormal, Drug ineffective,

IMATINIB, IMATINIB, PANTOPRAZOLE, PANTOPRAZOLE, CELECOXIB, ELTROMBOPAG OLAMINE, ELTROMBOPAG, NILOTINIB, DASATINIB, CALCIUM CARBONATE, ANTACID, LISINOPRIL, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, PAROXETINE HYDROCHLORIDE, OXAZEPAM, THIAMINE HYDROCHLORIDE, RIBOFLAVIN 5 PHOSPHATE SODIUM, DEXPANTHENOL AND NIACINAMIDE, HYDROXYUREA, AMLODIPINE, AMLODIPINE,

26915528

EU

International normalised ratio increased, Anaemia,

OSELTAMIVIR PHOSPHATE, WARFARIN SODIUM, WARFARIN,

26915533

CA

Abdominal distension, Abdominal pain, Anaemia, Analgesic therapy, Appendicitis, Appendicolith, Ascites, Bacterial infection, Blood cholesterol increased, Blood phosphorus increased, Blood uric acid increased, Cardiogenic shock, Chronic obstructive pulmonary disease, Condition aggravated, Constipation, Diabetes mellitus, Drug hypersensitivity, Drug intolerance, Drug therapy, Dry mouth, Dyspnoea, General physical health deterioration, Hyperphosphataemia, Intentional product misuse, Multiple organ dysfunction syndrome, Myasthenia gravis, Nausea, Neuralgia, Pulmonary embolism, Off label use, Sepsis, Sleep disorder, Sleep disorder therapy, Somnolence, Stress, Swelling, Thrombosis, Ventricular fibrillation, Vomiting, Hyponatraemia,

CALCITRIOL, CALCITRIOL CAPSULES 0.25 MCG, CALCITRIOL CAPSULES 0.5 MCG, CALCITRIOL, CALCITRIOL CAPSULES 0.25 MCG, CALCITRIOL CAPSULES 0.5 MCG, LIDOCAINE, LIDOCAINE HYDROCHLORIDE, BURN RELIEF, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE, LIDICAINE, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE, LIDOCAINE 4%, LIDOCAINE, MENTHOL, OSELTAMIVIR, OSELTAMIVIR PHOSPHATE, PHYTONADIONE,

26915713

MX

Breast cancer, Malignant neoplasm progression, Cardio-respiratory arrest, Hepatitis, Asthenia, Back pain, Pruritus, Hair growth abnormal, Weight increased, Increased appetite, Dyspepsia, Drug hypersensitivity, Pharyngeal inflammation, Dyspepsia, Pharyngeal inflammation, Dysphagia, Decreased immune responsiveness, Anaemia, Constipation, Dizziness, Influenza, Pain, Malaise, Arthralgia, Pyrexia, Eye infection, Photophobia, Dry skin, Weight decreased, Bone pain, Drug ineffective,

ANASTROZOLE, ANASTROZOLE TABLETS, ANASTROZOLE, ANASTROZOLE TABLETS, RIBOCICLIB, RIBOCICLIB, RIBOCICLIB, RIBOCICLIB, RIBOCICLIB, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ANASTROZOLE, ANASTROZOLE TABLETS,

26915852

CN

Death, Metastases to central nervous system, Anaemia, Platelet count decreased, White blood cell count decreased, Nausea, Diarrhoea,

IRINOTECAN HYDROCHLORIDE, LEUCOVORIN CALCIUM, FLUOROURACIL CREAM, 0.5%, FLUOROURACIL,

26916541

KR

Pancytopenia, Pruritus, Anaemia, Myalgia, Nausea, Tremor, Abdominal pain, Rash, Red blood cell transfusion, Asthenia, Syncope, Cytopenia, Vomiting, Acute kidney injury, Functional endoscopic sinus surgery, Febrile neutropenia,

PEMBROLIZUMAB, PEMBROLIZUMAB, PEMBROLIZUMAB, TETRACYCLINE HYDROCHLORIDE, TETRACYCLINE HYDROCHLORIDE, TETRACYCLINE HYDROCHLORIDE, TETRACYCLINE HYDROCHLORIDE, TETRACYCLINE HYDROCHLORIDE, TETRACYCLINE HYDROCHLORIDE,

26916615

CN

Rash, Seizure, Urinary retention, Hot flush, Fatigue, Anaemia, Weight increased, Asthenia, Hypertension, Pruritus, Bone pain, Back pain, Constipation, Blood alkaline phosphatase increased, Arthralgia, Pain in extremity, Fall,

APALUTAMIDE,

26916805

EU

Anaemia, COVID-19, Drug ineffective,

BENDAMUSTINE HCL, BRENTUXIMAB VEDOTIN, RITUXIMAB, DOXORUBICIN, DACARBAZINE,

26916810

Anaemia, Melaena,

RIVAROXABAN, FUROSEMIDE, POTASSIUM CHLORIDE, POTASSIUM CHLORIDE EXTENDED-RELEASE, POTASSIUM CHLORIDE, DEXTROSE MONOHYDRATE, POTASSIUM CHLORIDE ORAL, VALSARTAN, VALSARTAN ORAL, ALFUZOSIN HYDROCHLORIDE, MONTELUKAST SODIUM, CETIRIZINE HYDROCHLORIDE, CETIRIZINE, CETIRIZINE HYDROCHLORIDE ALLERGY, CETIRIZINE HYDROCHLORIDE TABLETS, FAMOTIDINE,

26917057

Abnormal uterine bleeding, Anaemia, Endometrial cancer stage III,

RIOCIGUAT,

26917363

EU

Blood loss anaemia, Splenomegaly, Anaemia, Pain in extremity, Mean cell haemoglobin concentration abnormal, Platelet count abnormal, Therapy partial responder,

RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, AMLODIPINE, VALSARTAN, VALSARTAN ORAL, BISOPROLOL FUMARATE, DOXAZOSIN, DOXAZOSIN MESYLATE, APIXABAN, PROPAFENONE, TORSEMIDE, EPLERENONE, THEOPHYLLINE, THEOPHYLLINE ANHYDROUS, AMITRIPTYLINE HYDROCHLORIDE, FENOFIBRATE, ALPRAZOLAM, DABIGATRAN ETEXILATE,

26917417

US

Death, Neuropathy peripheral, Cardiomyopathy, Cardiac failure, Leukopenia, Neutropenia, Thrombocytopenia, Atrial fibrillation, Lymphopenia, Anaemia, Off label use,

DARATUMUMAB,

26917690

CN

Tubulointerstitial nephritis, Off label use, Immune-mediated dermatitis, Eczema, Immune-mediated nephritis, Immune-mediated adverse reaction, Renal impairment, Decreased appetite, Papule, Pruritus, Rash, Skin exfoliation, Immune thrombocytopenia, Platelet production decreased, Anaemia, Hyperglycaemia,

OXALIPLATIN, OXALIPLATIN, OXALIPLATIN,

26917954

US

Anaemia, Dyspnoea, Weight decreased, Diarrhoea, Drug ineffective, Constipation, Choking, Tremor, Product dose omission issue, Illness, Headache, Fall, Wrist fracture, Dizziness, Balance disorder, Migraine, Cough, Decreased appetite, Pruritus, Depression, Gastrointestinal disorder, Wound, Back pain, Intentional product use issue, Neck pain, Mobility decreased, Osteoporosis, Breath sounds abnormal, Lung disorder, Therapeutic response unexpected, Head discomfort,

NINTEDANIB, NINTEDANIB, NINTEDANIB, NINTEDANIB,

26918174

CA

Blood pressure increased, Syncope, Blood iron decreased, Cystitis, Cellulitis, Back pain, Neuralgia, Pain, Hypoaesthesia, Paraesthesia, Diabetes mellitus, Cholelithiasis, Haemorrhage, Hypothyroidism, Endometrial cancer stage I, Second primary malignancy, Nephrolithiasis, Renal impairment, Renal failure, Procedural pain, Carcinoid tumour, Metastases to ovary, Metastases to fallopian tube, Metastases to bladder, Malignant neoplasm progression, Palpitations, Arthralgia, Subcutaneous haematoma, Pain in extremity, Muscle spasms, Peripheral swelling, Serum serotonin increased, Vertigo, Urine output decreased, Myalgia, Contusion, Hepatic pain, Muscle tightness, Groin pain, Nasopharyngitis, White blood cell count increased, Haemoglobin decreased, Urinary tract infection, Acne, Liver function test increased, Hypomenorrhoea, Polyp, Blood urine present, Abdominal adhesions, Endometriosis, Endometrial hyperplasia, Poor quality sleep, Pyrexia, Chills, Cough, Migraine, Anaemia, Blood pressure systolic decreased, Blood pressure diastolic decreased, Joint swelling, Arthritis, Crystal arthropathy, Gout, Joint stiffness, Malaise, Peripheral swelling, Erythema, Joint swelling, Rash pruritic, Asthenia, Heart rate decreased, Vomiting, Dizziness, Abdominal pain, Abdominal tenderness, Rash papular, Diarrhoea, Fatigue, Nausea, Decreased appetite, Injection site mass, Injection site pain, Injection site pain, Injection site reaction, Injection site erythema, Needle issue,

AMLODIPINE, AMLODIPINE, CANDESARTAN CILEXETIL, CANDESARTAN CILEXETIL, CANDESARTAN CILEXETIL, CANDESARTAN CILEXETIL, OCTREOTIDE ACETATE, OCTREOTIDE ACETATE, OCTREOTIDE ACETATE, OCTREOTIDE ACETATE, HYDROCHLOROTHIAZIDE, HYDROCHLOROTHIAZIDE, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, CLOPIDOGREL, CLOPIDOGREL BISULFATE,

26918614

CA

Intestinal anastomosis, Therapeutic product effect incomplete, Inflammation, Anaemia,

26919160

Neutropenia, Metastases to meninges, Anaemia, Alopecia,

26919182

EU

Oedema peripheral, Blood pressure increased, Hypotension, Constipation, Haemorrhage, Anaemia, Blood fibrinogen decreased,

ALBUTEROL SULFATE, ALBUTEROL, MIDAZOLAM, MIDAZOLAM HYDROCHLORIDE, CAPTOPRIL, TRANEXAMIC ACID, DEXMEDETOMIDINE,

26919287

EU

Anaemia,

CLOZAPINE,

26919290

US

Acute kidney injury, Anaemia, Hypertension,

ECULIZUMAB,

26920892

EU

Hypothyroidism, Neutropenia, Neutropenia, Neutropenia, Anaemia, Anaemia, Anaemia, Anaemia, Oedema peripheral, Mucosal inflammation,

PEMETREXED, PEMETREXED DISODIUM, PEMETREXED, PEMETREXED DISODIUM, PEMETREXED, PEMETREXED DISODIUM, PEMETREXED, PEMETREXED DISODIUM, PEMBROLIZUMAB, PEMBROLIZUMAB, PEMBROLIZUMAB, PEMBROLIZUMAB, CARBOPLATIN, CARBOPLATIN, CARBOPLATIN, CARBOPLATIN,

26921175

Peritonitis, Candida sepsis, Anaemia, Thrombocytopenia, Gamma-glutamyltransferase increased, Neutropenia, Blood alkaline phosphatase increased, Off label use,

CETUXIMAB, CETUXIMAB, CETUXIMAB, ENCORAFENIB, ENCORAFENIB, FLUOROURACIL CREAM, 0.5%, FLUOROURACIL, OXALIPLATIN, DIMENHYDRINATE, METOCLOPRAMIDE, METOCLOPRAMIDE HYDROCHLORIDE,

26923706

Anaemia, Infusion related reaction, Hypotension, Chest pain, Cough, Wheezing, Atypical pneumonia, Pneumonia, Gastrointestinal haemorrhage, Haemorrhoids,

MELOXICAM,

26910229

CA

Gastrointestinal angiodysplasia, Hepatic enzyme increased, Red blood cell transfusion, Dyspnoea, Asthenia, Anaemia, Acute kidney injury,

RIVAROXABAN, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, BISOPROLOL FUMARATE, CEFADROXIL, CELECOXIB, DEXLANSOPRAZOLE, DOCUSATE SODIUM, DOCUSATE SODIUM 100MG, FERROUS SULFATE, FUROSEMIDE, ALBUTEROL SULFATE, ALBUTEROL, DULOXETINE HYDROCHLORIDE, SPIRONOLACTONE, TIOTROPIUM BROMIDE,

26910521

CA

Blood pressure increased, Syncope, Blood iron decreased, Cystitis, Cellulitis, Back pain, Neuralgia, Pain, Hypoaesthesia, Paraesthesia, Diabetes mellitus, Cholelithiasis, Haemorrhage, Hypothyroidism, Endometrial cancer stage I, Second primary malignancy, Nephrolithiasis, Renal impairment, Renal failure, Procedural pain, Carcinoid tumour, Metastases to ovary, Metastases to fallopian tube, Metastases to bladder, Malignant neoplasm progression, Palpitations, Arthralgia, Subcutaneous haematoma, Pain in extremity, Muscle spasms, Peripheral swelling, Serum serotonin increased, Vertigo, Urine output decreased, Myalgia, Contusion, Hepatic pain, Muscle tightness, Groin pain, Nasopharyngitis, White blood cell count increased, Haemoglobin decreased, Urinary tract infection, Acne, Liver function test increased, Hypomenorrhoea, Polyp, Blood urine present, Abdominal adhesions, Endometriosis, Endometrial hyperplasia, Poor quality sleep, Pyrexia, Chills, Cough, Migraine, Anaemia, Blood pressure systolic decreased, Blood pressure diastolic decreased, Joint swelling, Arthritis, Crystal arthropathy, Gout, Joint stiffness, Malaise, Peripheral swelling, Erythema, Joint swelling, Rash pruritic, Asthenia, Heart rate decreased, Vomiting, Dizziness, Abdominal pain, Abdominal tenderness, Rash papular, Diarrhoea, Fatigue, Nausea, Decreased appetite, Injection site mass, Injection site pain, Injection site pain, Injection site reaction, Injection site erythema, Needle issue,

OCTREOTIDE ACETATE, OCTREOTIDE ACETATE, OCTREOTIDE ACETATE, OCTREOTIDE ACETATE, OCTREOTIDE ACETATE, OCTREOTIDE ACETATE, AMLODIPINE, AMLODIPINE, CANDESARTAN CILEXETIL, CANDESARTAN CILEXETIL, CANDESARTAN CILEXETIL, CANDESARTAN CILEXETIL, HYDROCHLOROTHIAZIDE, HYDROCHLOROTHIAZIDE, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, CLOPIDOGREL, CLOPIDOGREL BISULFATE,

26910647

CO

Hepatic cirrhosis, Surgery, Ascites, Contusion, Post procedural swelling, Medical procedure, Ill-defined disorder, Blood glucose increased, Blood pressure abnormal, Anaemia, Platelet count abnormal,

ROMIPLOSTIM,

26910729

EU

Presyncope, Nausea, Anaemia, Deep vein thrombosis,

CISPLATIN, CAPECITABINE, PEMBROLIZUMAB,

26911183

JP

Neutropenia, Anaemia,

DOXORUBICIN, DOXORUBICIN, CISPLATIN, CISPLATIN, ETOPOSIDE, ETOPOSIDE, MITOTANE, MITOTANE,

26911296

JP

Leukopenia, Neutropenia, Anaemia, Dysgeusia, Product use in unapproved indication,

ERIBULIN MESYLATE, ERIBULIN MESYLATE, PEGFILGRASTIM,

26911299

CN

Anaemia, Hyperbilirubinaemia, Asthenia, Decreased appetite, Nausea, Alanine aminotransferase increased, Aspartate aminotransferase increased, Cholecystitis, Renal cyst, Intra-abdominal fluid collection, Ascites, Activated partial thromboplastin time ratio decreased, Blood albumin decreased,

ALECTINIB HYDROCHLORIDE, SIROLIMUS,

26911306

JP

Leukopenia, Neutropenia, Anaemia, Product use in unapproved indication,

ERIBULIN MESYLATE, ERIBULIN MESYLATE, PEGFILGRASTIM,

26911307

JP

Leukopenia, Dysgeusia, Neutropenia, Anaemia, Product use in unapproved indication,

ERIBULIN MESYLATE, ERIBULIN MESYLATE, PEGFILGRASTIM,

26911313

JP

Leukopenia, Neutropenia, Neuropathy peripheral, Anaemia, Product use in unapproved indication,

ERIBULIN MESYLATE, ERIBULIN MESYLATE, PEGFILGRASTIM,

26911332

US

Fatigue, Anaemia, White blood cell count decreased,

RELUGOLIX,

26911673

CN

Hypokalaemia, Immune-mediated enterocolitis, Febrile neutropenia, Myelosuppression, Pneumonia, Upper gastrointestinal haemorrhage, Thrombosis, Hypocalcaemia, Hypochloraemia, Hyponatraemia, Anaemia, Hypoalbuminaemia, Hypomagnesaemia, Oral disorder, Pyrexia, Stomatitis, Platelet count decreased, White blood cell count decreased, Cough, Dizziness, Fatigue,

NIVOLUMAB, CISPLATIN, FLUOROURACIL CREAM, 0.5%, FLUOROURACIL,

26911785

EU

Oedema peripheral, Blood pressure increased, Hypotension, Constipation, Haemorrhage, Anaemia, Blood fibrinogen decreased,

ALBUTEROL SULFATE, ALBUTEROL, MIDAZOLAM, MIDAZOLAM HYDROCHLORIDE, TRANEXAMIC ACID, DEXMEDETOMIDINE, CAPTOPRIL,

26911840

US

Anaemia,

ISOTRETINOIN, ISOTRETINOIN,

26911919

CA

Blood pressure increased, Syncope, Blood iron decreased, Cystitis, Cellulitis, Back pain, Neuralgia, Pain, Hypoaesthesia, Paraesthesia, Diabetes mellitus, Cholelithiasis, Haemorrhage, Hypothyroidism, Endometrial cancer stage I, Second primary malignancy, Nephrolithiasis, Renal impairment, Renal failure, Procedural pain, Carcinoid tumour, Metastases to ovary, Metastases to fallopian tube, Metastases to bladder, Malignant neoplasm progression, Palpitations, Arthralgia, Subcutaneous haematoma, Pain in extremity, Muscle spasms, Peripheral swelling, Serum serotonin increased, Vertigo, Urine output decreased, Myalgia, Contusion, Hepatic pain, Muscle tightness, Groin pain, Nasopharyngitis, White blood cell count increased, Haemoglobin decreased, Urinary tract infection, Acne, Liver function test increased, Hypomenorrhoea, Polyp, Blood urine present, Abdominal adhesions, Endometriosis, Endometrial hyperplasia, Poor quality sleep, Pyrexia, Chills, Cough, Migraine, Anaemia, Blood pressure systolic decreased, Blood pressure diastolic decreased, Joint swelling, Arthritis, Crystal arthropathy, Gout, Joint stiffness, Malaise, Peripheral swelling, Erythema, Joint swelling, Rash pruritic, Asthenia, Heart rate decreased, Vomiting, Dizziness, Abdominal pain, Abdominal tenderness, Rash papular, Diarrhoea, Fatigue, Nausea, Decreased appetite, Injection site mass, Injection site pain, Injection site pain, Injection site reaction, Injection site erythema, Needle issue,

AMLODIPINE, AMLODIPINE, CANDESARTAN CILEXETIL, CANDESARTAN CILEXETIL, CANDESARTAN CILEXETIL, CANDESARTAN CILEXETIL, OCTREOTIDE ACETATE, OCTREOTIDE ACETATE, OCTREOTIDE ACETATE, OCTREOTIDE ACETATE, HYDROCHLOROTHIAZIDE, HYDROCHLOROTHIAZIDE, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, CLOPIDOGREL, CLOPIDOGREL BISULFATE,

26912009

CA

Acne, Nausea, Serum ferritin decreased, Concomitant disease aggravated, Anaemia, Colitis ulcerative, C-reactive protein increased, Swelling face, Dizziness, Weight increased, Lack of concomitant drug effect, Labelled drug-drug interaction issue,

ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, IRON, MESALAMINE, PANTOPRAZOLE, PREDNISONE, VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE,

26912086

EU

Polyneuropathy, Anaemia,

CARBOPLATIN, PACLITAXEL, PACLITAXEL (AIBUMIN-BOUND), DOSTARLIMAB,

26912093

EU

Blast crisis in myelogenous leukaemia, Treatment failure, Drug ineffective, Disease progression, Anaemia,

IMATINIB, DASATINIB, ASCIMINIB, BOSUTINIB,

26912121

EU

Gastric ulcer haemorrhage, Anaemia,

ETOPOSIDE, METHOTREXATE SODIUM, CYCLOPHOSPHAMIDE FOR INJECTION, CYCLOPHOSPHAMIDE, CYCLOPHOSPHAMIDE INJECTION, SOLUTION, PREDNISONE, IFOSFAMIDE, DEXAMETHASONE, DEXAMETHASONE 1.5 MG, CYTARABINE, RITUXIMAB,

26912443

EU

Seizure, Arthritis, Herpes virus infection, Upper respiratory tract infection, Anaemia,

SACITUZUMAB GOVITECAN,

26912478

EU

Anaemia, Acute kidney injury, Diarrhoea,

IRINOTECAN HYDROCHLORIDE, LEUCOVORIN CALCIUM, FLUOROURACIL CREAM, 0.5%, FLUOROURACIL,

26912774

CN

Myelosuppression, Infection, Asthenia, Anaemia, Abdominal pain upper, Insomnia, Pyrexia,

CYTARABINE, IDARUBICIN HYDROCHLORIDE,

26913101

EU

Gastric ulcer haemorrhage, Anaemia,

RITUXIMAB, METHOTREXATE, METHOTREXATE SODIUM, CYCLOPHOSPHAMIDE FOR INJECTION, CYCLOPHOSPHAMIDE, CYCLOPHOSPHAMIDE INJECTION, SOLUTION, PREDNISONE, IFOSFAMIDE, DEXAMETHASONE, DEXAMETHASONE 1.5 MG, CYTARABINE, VINCRISTINE SULFATE, ETOPOSIDE,

26913181

EU

Hepatotoxicity, Rash maculo-papular, Hypothyroidism, Colitis, Pneumonitis, Alanine aminotransferase increased, Blood alkaline phosphatase increased, Hypersensitivity, Anaemia, Anorectal infection, Aspartate aminotransferase increased, Blood bilirubin increased, Cholangitis, Colitis, Diarrhoea, Fatigue, Dyspnoea, Febrile neutropenia, Gastritis, Hepatotoxicity, Hypertension, Kidney infection, Kidney infection, Pneumonia, Neuralgia, Neutrophil count decreased, Platelet count decreased, Psychotic disorder, Sepsis, Embolism, Urinary fistula, Urinary tract infection, Uterine infection, Vaginal haemorrhage, Arthritis, Blood corticotrophin decreased, Blood prolactin abnormal, Vision blurred, Blood creatinine increased, Diabetes mellitus, Dry eye, Oesophageal infection, Pyrexia, Gamma-glutamyltransferase increased, Headache, Hyperglycaemia, Hyperthyroidism, Hypomagnesaemia, Hypophysitis, Pain, Peripheral sensory neuropathy, Pharyngitis, Proteinuria, Pruritus, Renal disorder, Urinary tract disorder, Skin disorder, Blood thyroid stimulating hormone increased,

ATEZOLIZUMAB, ATEZOLIZUMAB, BEVACIZUMAB, BEVACIZUMAB,

26913324

US

Anaemia, Red blood cell count decreased, Fatigue, Dyspnoea exertional, Loss of personal independence in daily activities, Pain in extremity, Gait disturbance, Hypokinesia, Chronic obstructive pulmonary disease, Asthma,

DUPILUMAB, DUPILUMAB,

26913345

Hypertension, Amylase increased, Photosensitivity reaction, Depression, Hallucination, Speech disorder, Oedema, Hypotension, Bradycardia, Anaemia, Arthralgia,

LORLATINIB, BRIGATINIB, ALECTINIB HYDROCHLORIDE,

26913680

US

Anaemia, Small intestinal obstruction,

POMALIDOMIDE, LENALIDOMIDE, AMLODIPINE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, EZETIMIBE, HYDROCHLOROTHIAZIDE, LATANOPROST, TELMISARTAN, VALACYCLOVIR, VALACYCLOVIR HYDROCHLORIDE,

26913794

Renal failure, Blood creatinine increased, Thrombocytopenia, Anaemia, Off label use,

FAM-TRASTUZUMAB DERUXTECAN-NXKI,

26913865

US

Optic atrophy, Anaemia,

SELUMETINIB,

26905424

CN

Anaemia, Nausea, Vomiting, Gastrooesophageal reflux disease, Dyspepsia, Eructation, Asthenia, Decreased appetite, Abdominal pain,

OXALIPLATIN, OXALIPLATIN, OXALIPLATIN, PACLITAXEL, PACLITAXEL (AIBUMIN-BOUND), PACLITAXEL, PACLITAXEL (AIBUMIN-BOUND), CAPECITABINE, SODIUM CHLORIDE, SODIUM CHLORIDE TABLET, SODIUM CHLORIDE TABLETS, SODIUM CHLORIDE, SODIUM CHLORIDE TABLET, SODIUM CHLORIDE TABLETS, SODIUM CHLORIDE, SODIUM CHLORIDE TABLET, SODIUM CHLORIDE TABLETS, SODIUM CHLORIDE, SODIUM CHLORIDE TABLET, SODIUM CHLORIDE TABLETS, SODIUM CHLORIDE, SODIUM CHLORIDE TABLET, SODIUM CHLORIDE TABLETS, DEXTROSE MONOHYDRATE, DEXTROSE, DEXTROSE MONOHYDRATE, DEXTROSE, DEXTROSE MONOHYDRATE, DEXTROSE,

26905441

JP

Thrombosis, Anaemia, Blood creatinine increased,

26905521

JP

Renal impairment, Anaemia,

PEMBROLIZUMAB, PEMBROLIZUMAB, GEMCITABINE HYDROCHLORIDE, GEMCITABINE, GEMCITABINE HYDROCHLORIDE, GEMCITABINE, CISPLATIN, CISPLATIN,

26905736

US

Death, Hyperkalaemia, Chronic kidney disease, Blood creatine increased, Blood pressure inadequately controlled, Glomerular filtration rate decreased, Anaemia,

DAPAGLIFLOZIN, AMLODIPINE, CETIRIZINE, CETIRIZINE HYDROCHLORIDE, CETIIRIZINE, CLOPIDOGREL, CLOPIDOGREL BISULFATE, DARBEPOETIN ALFA, FERROUS SULFATE, FUROSEMIDE, HYDROXYZINE, LATANOPROST, LOVASTATIN, MIRABEGRON, PATIROMER, SODIUM BICARBONATE, SODIUM BICARBONATE, INJECTION, SODIUM BICARBONATE INJECTION,, SODIUM CHLORIDE, SODIUM CHLORIDE TABLET, SODIUM CHLORIDE TABLETS, TIMOLOL,

26905759

EU

Thrombocytopenia, Febrile neutropenia, Anaemia, Neutropenia, Acute kidney injury, Aspartate aminotransferase increased, Alanine aminotransferase increased, Mucosal inflammation,

RITUXIMAB, METHOTREXATE, METHOTREXATE SODIUM, CYCLOPHOSPHAMIDE FOR INJECTION, CYCLOPHOSPHAMIDE, CYCLOPHOSPHAMIDE INJECTION, SOLUTION, DOXORUBICIN, PREDNISONE,

26905785

US

Anaemia,

BISOPROLOL FUMARATE, RIVAROXABAN, IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN TABLET, FILM COATED, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, BUMETANIDE,