Drug Search by Year (Detail)

25124805

DK

Cerebrovascular accident, Drug interaction,

NINTEDANIB, WARFARIN,

25125049

JP

Immunosuppressant drug level increased, Renal impairment, Nephropathy toxic, Bronchopulmonary aspergillosis, Drug interaction, Off label use,

TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, EVEROLIMUS, EVEROLIMUS TABLETS, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, RABEPRAZOLE, AMLODIPINE, SITAGLIPTIN, REPAGLINIDE, MIGLITOL, LEMBOREXANT, LEMBOREXANT,

25125195

US

Intentional self-injury, Agitation, Aggression, Drug interaction,

CANNABIDIOL, CLOBAZAM,

25125291

AU

Neutropenia, Toxicity to various agents, Cytopenia, Drug interaction,

AZACITIDINE, AZACITIDINE FOR, VENETOCLAX,

25125541

US

BRASH syndrome, Drug interaction,

CARVEDILOL, VALSARTAN, HYDROCHLOROTHIAZIDE,

25125672

FR

Somnolence, Drug interaction, Drug level decreased, Drug interaction,

CARBAMAZEPINE, MIRTAZAPINE, ABACAVIR SULFATE, DOLUTEGRAVIR SODIUM, LAMIVUDINE, ATAZANAVIR, RITONAVIR, PERAMPANEL,

25125706

US

Drug interaction,

APALUTAMIDE, APIXABAN,

25125751

US

Drug interaction, Product use in unapproved indication,

TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, COLCHICINE, COLCHICINE,

25125794

ES

Overdose, Drug interaction, Product use in unapproved indication, Acute respiratory failure,

DEXMEDETOMIDINE HYDROCHLORIDE IN SODIUM CHLORIDE, DEXMEDETOMIDINE HYDROCHLORIDE, DEXMEDETOMIDINE HYDROCHLORIDE IN 0.9% SODIUM CHLORIDE, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), MIDAZOLAM, MIDAZOLAM HYDROCHLORIDE, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE),

25125892

RU

Gingival hypertrophy, Drug interaction,

AMLODIPINE, CYCLOSPORINE,

25125964

US

Empyema, Pleural effusion, Drug interaction, Respiratory failure,

CLOZAPINE, CLOZAPINE,

25125985

CA

Drug interaction, Drug level increased, Dysarthria, Dysstasia, Dizziness, Accidental overdose, Intentional dose omission,

NAPROXEN, NAPROXEN SODIUM, LORAZEPAM, CLOBAZAM, DIVALPROEX SODIUM, LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE,

25126047

AU

Myocarditis, Drug interaction, Treatment failure, Off label use,

CLOZAPINE, OLANZAPINE, PALIPERIDONE, VALPROIC ACID,

25115829

US

Drug interaction, Arteriospasm coronary, Acute myocardial infarction,

SUMATRIPTAN SUCCINATE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG,

25116002

US

Cough, Fatigue, Diarrhoea, Drug tolerance decreased, Drug interaction, Extra dose administered, Incorrect product administration duration,

TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, NINTEDANIB,

25116137

GB

Pulmonary embolism, Drug interaction,

CARBAMAZEPINE, RIVAROXABAN, LETROZOLE, LETROZOLE TABLETS,

25116138

IT

Transient ischaemic attack, Drug interaction,

CARBAMAZEPINE, APIXABAN, RAMIPRIL,

25116462

US

Influenza, Heart rate irregular, Drug interaction, Dental operation,

MIRTAZAPINE, LENVATINIB,

25116548

JP

Off label use, Testicular neoplasm, Myelosuppression, Pancreatitis, Anaemia, Platelet count decreased, Neutrophil count decreased, Febrile neutropenia, Scleroderma-like reaction, Drug level increased, Drug interaction, Cytomegalovirus infection,

VALGANCICLOVIR HYDROCHLORIDE, VALGANCICLOVIR, METHYLPREDNISOLONE, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, ETOPOSIDE, ETOPOSIDE, CISPLATIN, BLEOMYCIN, BLEOMYCIN SULFATE, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE,

25116833

DE

Drug ineffective, Pancreatitis, Ataxia, Vision blurred, Diplopia, Dysarthria, Sedation, Epilepsy, Rebound effect, Drug interaction,

CARBAMAZEPINE, CARBAMAZEPINE, CARBAMAZEPINE, CARBAMAZEPINE, LACOSAMIDE, LACOSAMIDE, LACOSAMIDE, LACOSAMIDE, LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE, LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE, LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE, LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE, TOPIRAMATE, TOPIRAMATE SPINKLE, TOPIRAMATE, TOPIRAMATE SPINKLE, TOPIRAMATE, TOPIRAMATE SPINKLE, TOPIRAMATE, TOPIRAMATE SPINKLE, ZONISAMIDE, ZONISAMIDE, ZONISAMIDE, ZONISAMIDE, PHENOBARBITAL, PHENOBARBITAL, PHENOBARBITAL, PHENOBARBITAL, PHENOBARBITAL, OXCARBAZEPINE, OXCARBAZEPINE, OXCARBAZEPINE, OXCARBAZEPINE, PHENYTOIN, PHENYTOIN, PHENYTOIN, PHENYTOIN, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES,

25116964

Nephropathy toxic, Drug interaction, Renal impairment, Drug level increased, Off label use,

TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, EVEROLIMUS, EVEROLIMUS TABLETS, RABEPRAZOLE, AMLODIPINE, SITAGLIPTIN, REPAGLINIDE, MIGLITOL, LEMBOREXANT, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, LEMBOREXANT,

25117246

CA

Loss of personal independence in daily activities, Drug interaction, Off label use, Depression,

ATAZANAVIR SULFATE, ATAZANAVIR, BUPROPION HYDROCHLORIDE, CLONAZEPAM, EFAVIRENZ, LOPINAVIR AND RITONAVIR, LAMIVUDINE, LAMIVUDINE ORAL, QUETIAPINE FUMARATE, QUETIAPINE, RALTEGRAVIR, SERTRALINE HYDROCHLORIDE, VALPROATE SODIUM, VALPROIC ACID, ENFUVIRTIDE, ENFUVIRTIDE,

25117269

GB

Immunosuppression, Drug interaction, Mycobacterium marinum infection,

PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION,

25117595

US

Dizziness, Myalgia, Flushing, Rash, Agitation, Drug interaction,

OMALIZUMAB, HYDROXYZINE, METHOCARBAMOL, METHOCARBAMOL TABLETS,

25117657

JP

Prothrombin time prolonged, Drug interaction,

WARFARIN, WARFARIN, BOSENTAN, MACITENTAN,

25118006

ES

Drug interaction, Supraventricular tachyarrhythmia,

AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, HYDROXYCHLOROQUINE, CEFTRIAXONE, CEFTRIAXONE SODIUM, CEFEPIME HYDROCHLORIDE, CEFEPIME, LINEZOLID, PIPERACILLIN SODIUM AND TAZOBACTAM SODIUM, PIPERACILLIN AND TAZOBACTAM, PIPERACILLIN SODIUM,TAZOBACTAM SODIUM, VANCOMYCIN HYDROCHLORIDE, VANCOMYCIN, ACETYLCYSTEINE,

25118224

DE

Respiratory acidosis, Hypercapnic coma, Acute kidney injury, Neurological decompensation, Toxicity to various agents, Drug abuse, Drug interaction,

DEXMEDETOMIDINE HYDROCHLORIDE IN SODIUM CHLORIDE, DEXMEDETOMIDINE HYDROCHLORIDE, DEXMEDETOMIDINE HYDROCHLORIDE IN 0.9% SODIUM CHLORIDE, RAMIPRIL, TORSEMIDE, CLONIDINE, SUFENTANIL, GABAPENTIN, ALLOPURINOL, LEVOTHYROXINE, BISOPROLOL FUMARATE,

25118298

JP

Drug interaction,

DASATINIB, ESOMEPRAZOLE MAGNESIUM, ESOMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM DELAYED RELEASE CAPSULES,

25118440

NL

Drug hypersensitivity, Drug interaction, Product use in unapproved indication,

ALLOPURINOL, METHOTREXATE, METHOTREXATE SODIUM,

25118508

ES

Drug interaction, Rhabdomyolysis, Off label use,

ROSUVASTATIN, PREDNISONE, PREDNISONE, ABIRATERONE ACETATE, ABIRATERONE, ABIRATERONE ACETATE, ABIRATERONE,

25119296

US

Hepatotoxicity, Ocular toxicity, Drug interaction, Drug intolerance, Product use in unapproved indication,

RIFAMPIN, ETHAMBUTOL HYDROCHLORIDE, AZITHROMYCIN, AZITHROMYCIN MONOHYDRATE, AZITHROMYCIN DIHYDRATE, AMIKACIN,

25119443

GB

Medication error, Drug interaction,

LEVOTHYROXINE, PREGABALIN, MIRABEGRON, LANSOPRAZOLE,

25119447

CA

Depressed level of consciousness, Electrocardiogram QT prolonged, Fall, Hypertension, Mental disorder, Nephropathy toxic, Serotonin syndrome, Toxicity to various agents, Drug intolerance, Drug interaction, Drug ineffective, Off label use, Drug ineffective for unapproved indication, Contraindicated product administered,

PROPRANOLOL HYDROCHLORIDE, PROPRANOLOL HYDROCHLORIDE, PROPRANOLOL HYDROCHLORIDE, PROPRANOLOL HYDROCHLORIDE, PROPRANOLOL HYDROCHLORIDE, DULOXETINE HYDROCHLORIDE, DULOXETINE, TOPIRAMATE, TOPIRAMATE SPINKLE, TOPIRAMATE, TOPIRAMATE SPINKLE, ERENUMAB-AOOE, CANDESARTAN, CANDESARTAN, DULOXETINE HYDROCHLORIDE, GABAPENTIN, GABAPENTIN, INDOMETHACIN, MIRTAZAPINE, MIRTAZAPINE, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, OXYCODONE, BOTULINUM TOXIN TYPE A, DIVALPROEX SODIUM,

25119864

DE

Respiratory acidosis, Hypercapnic coma, Acute kidney injury, Neurological decompensation, Toxicity to various agents, Drug abuse, Drug interaction,

RAMIPRIL, TORSEMIDE, DEXMEDETOMIDINE, CLONIDINE, SUFENTANIL, GABAPENTIN, ALLOPURINOL, LEVOTHYROXINE, BISOPROLOL FUMARATE,

25119869

US

Completed suicide, Renal impairment, Seizure, Abnormal behaviour, Intrusive thoughts, Off label use, Intentional self-injury, Mood swings, Anger, Mydriasis, Drug interaction, Insomnia, Dizziness, Hallucination, auditory, Libido decreased, Drug withdrawal syndrome, Aggression, Drug ineffective,

DULOXETINE HYDROCHLORIDE, DULOXETINE HYDROCHLORIDE, LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, TESTOSTERONE, TESTOSTERONE,, TESTOSTERONE, TESTOSTERONE,, LORAZEPAM, LORAZEPAM,

25119958

US

Seizure, Drug interaction, Fatigue, Constipation, Insomnia, Product use issue,

BRIVARACETAM, BRIVARACETAM, TAURINE,

25120040

BE

Confusional state, Pain, Fatigue, Drug interaction,

RELUGOLIX, LEVETIRACETAM, PANTOPRAZOLE, LEVOTHYROXINE, CLOPIDOGREL, CLOPIDOGREL BISULFATE, EZETIMIBE, AMLODIPINE,

25120041

ES

Non-cardiogenic pulmonary oedema, Drug interaction, Toxicity to various agents,

VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, ALPRAZOLAM, ALPRAZOLAM, ALPRAZOLAM, ALPRAZOLAM, FENTANYL, FENTANYL, FENTANYL, FENTANYL, ZOLPIDEM TARTRATE, ZOLPIDEM TARTRATE, ZOLPIDEM TARTRATE, ZOLPIDEM TARTRATE, CLONAZEPAM, CLONAZEPAM, CLONAZEPAM, CLONAZEPAM, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), PROPOFOL, PROPOFOL, PROPOFOL, PROPOFOL,

25120231

AU

Myocarditis, Drug interaction, Treatment failure, Off label use,

ARIPIPRAZOLE ORALLY DISINTEGRATING, ARIPIPRAZOLE, ARIPIPRAZOLE ORAL, AMISULPRIDE, ASENAPINE, ASENAPINE MALEATE, CLOZAPINE, LURASIDONE HYDROCHLORIDE, OLANZAPINE, PAROXETINE HYDROCHLORIDE HEMIHYDRATE, PAROXETINE, PAROXETINE HYDROCHLORIDE, QUETIAPINE FUMARATE, QUETIAPINE, PALIPERIDONE,

25120362

AU

Drug interaction, Extrapyramidal disorder, Mania, Myocarditis, Treatment failure,

CLOZAPINE, LURASIDONE HYDROCHLORIDE, OLANZAPINE, RISPERIDONE,

25120396

DE

Drug interaction, Hypercapnic coma, Neurological decompensation, Toxicity to various agents, Respiratory acidosis, Acute kidney injury,

DEXMEDETOMIDINE HYDROCHLORIDE IN SODIUM CHLORIDE, DEXMEDETOMIDINE HYDROCHLORIDE, DEXMEDETOMIDINE HYDROCHLORIDE IN 0.9% SODIUM CHLORIDE, RAMIPRIL, TORSEMIDE, CLONIDINE, SUFENTANIL, GABAPENTIN, ALLOPURINOL, LEVOTHYROXINE, BISOPROLOL FUMARATE,

25129603

Bipolar I disorder, Hallucination, Hypersensitivity, Drug interaction,

LINEZOLID, BUPROPION HYDROCHLORIDE, BUPROPION,

25110223

US

Drug interaction, Dysstasia, Somnolence,

PIMAVANSERIN TARTRATE, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, LETROZOLE, LETROZOLE TABLETS, CETIRIZINE HYDROCHLORIDE, HYDRALAZINE HYDROCHLORIDE, CARVEDILOL, GABAPENTIN, ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, ROPINIROLE,

25111188

FR

Subdural haematoma, Drug interaction,

DULOXETINE HYDROCHLORIDE, DULOXETINE, CANDESARTAN CILEXETIL, LANSOPRAZOLE, SIMVASTATIN, HYDROCHLOROTHIAZIDE,

25111591

US

Electrocardiogram QT prolonged, Bundle branch block right, Drug interaction, Atrioventricular block first degree, Sinus bradycardia, Syncope,

LACOSAMIDE, APIXABAN,

25111595

US

BRASH syndrome, Acute kidney injury, Cardiogenic shock, Hyperkalaemia, Blood lactic acid increased, Nodal arrhythmia, Blood creatinine increased, Renal impairment, Hypotension, Hypovolaemia, Multiple drug therapy, Drug interaction, Diarrhoea,

VALSARTAN, HYDROCHLOROTHIAZIDE, CARVEDILOL,

25111855

EG

Hypotension, Coma, Drug interaction, Contraindicated product administered,

SILDENAFIL CITRATE, NITROGLYCERIN,

25112052

US

Glycosuria, Toxicity to various agents, Drug interaction, Off label use,

TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, NIRMATRELVIR AND RITONAVIR, PHENYTOIN, SODIUM CHLORIDE, SODIUM CHLORIDE INJECTION, SODIUM CHLORIDE TABLET, NORMAL SALT TABLETS, CEFTRIAXONE, CEFTRIAXONE SODIUM,

25112075

ES

Duodenal ulcer haemorrhage, Drug interaction,

PRASUGREL, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG,

25112341

US

Fall, Sedation, Fatigue, Drug interaction, Feeling abnormal,

BRIVARACETAM, LAMOTRIGINE,

25112369

US

Pericarditis constrictive, Serositis, Drug interaction, Off label use,

EVEROLIMUS, EVEROLIMUS TABLETS, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, COLCHICINE, COLCHICINE,

25112381

US

Diarrhoea, Nausea, Vomiting, Drug interaction,

BRIVARACETAM, BRIVARACETAM, ESCITALOPRAM, ESCITALOPRAM, TOPIRAMATE,

25112565

CH

Immunosuppressant drug level increased, Drug interaction,

LETERMOVIR, LETERMOVIR, TACROLIMUS, TACROLIMUS,

25113341

US

Drug interaction, Gastrointestinal haemorrhage,

PIPERACILLIN SODIUM,TAZOBACTAM SODIUM, RIVAROXABAN,

25113390

PT

Haemorrhagic stroke, Sepsis, Cardio-respiratory arrest, Altered state of consciousness, Headache, Diplopia, Pruritus, Sepsis, Haemorrhagic stroke, Fall, Diarrhoea, Blindness, Tachycardia, Fatigue, Pruritus, Asthenia, Urinary tract disorder, Haematemesis, Arthralgia, Myalgia, Syncope, Malaise, Photophobia, Cough, Vision blurred, Decreased appetite, Vomiting, Coma, Somnolence, Dizziness, Pyrexia, Somnolence, Blood pressure increased, Ocular discomfort, Head discomfort, Chills, Presyncope, Insomnia, Generalised oedema, Tinnitus, Amaurosis fugax, Dyspnoea, Ascites, Haematuria, Abdominal pain upper, Abdominal pain, Nausea, Drug interaction, Diplopia, Eye pain, Off label use,

MIRTAZAPINE, MIRTAZAPINE, MIRTAZAPINE, MIRTAZAPINE, EZETIMIBE, EZETIMIBE, EZETIMIBE, SIMVASTATIN, SIMVASTATIN, SIMVASTATIN, ALENDRONATE SODIUM, ALENDRONATE SODIUM,

25113564

NL

Acute kidney injury, Rhabdomyolysis, Toxicity to various agents, Drug interaction,

ABIRATERONE ACETATE, ABIRATERONE, ROSUVASTATIN, PREDNISONE,

25113801

GB

Drug interaction,

ELVITEGRAVIR, COBICISTAT, EMTRICITABINE, AND TENOFOVIR DISOPROXIL FUMARATE, NAPROXEN, NAPROXEN SODIUM, AMLODIPINE, INDAPAMIDE, DOXAZOSIN, DOXAZOSIN MESYLATE,

25113960

DE

Tinnitus, Drug interaction,

LISDEXAMFETAMINE DIMESYLATE, LISDEXAMFETAMINE, LISDEXAMFETAMINE DIMESYLATE CAPSULES, BUPROPION HYDROCHLORIDE, BUPROPION,

25114052

FR

Cardiac failure acute, Sinus bradycardia, Drug interaction,

BISOPROLOL FUMARATE,

25114075

US

Tardive dyskinesia, Product use issue, Off label use, Drug interaction,

DEUTETRABENAZINE, DEUTETRABENAZINE, BUPROPION HYDROCHLORIDE,

25114170

PL

Eye pruritus, Dizziness, Hyponatraemia, Hallucination, Cognitive disorder, Multiple drug therapy, Vertigo, Pruritus, Dementia, Hypoglycaemia, Urinary retention, Fall, Osteoporosis, Parkinsonism, Hiatus hernia, Drug dependence, Hyperkalaemia, Gastric polyps, Constipation, Dysuria, Atrioventricular block first degree, Blood pressure decreased, Mobility decreased, Depression, Arthralgia, Initial insomnia, Melaena, Blood urea increased, Labelled drug-drug interaction issue, Blood cholesterol decreased, Insomnia, Blood creatine increased, Abdominal pain upper, Hypotension, Syncope, Peripheral circulatory failure, Drug interaction, Drug ineffective, Malaise, Pericarditis, Cardiospasm, Atrial tachycardia, Muscular weakness, Anosmia, Lip swelling, Feeling abnormal, Dry skin, Amnesia, Pain, Diarrhoea, Facial pain, Dyspnoea, Palpitations, Chest pain, Tachycardia, Abdominal discomfort, Pyrexia, Angioedema, Ventricular tachycardia, Subarachnoid haemorrhage, Headache, Vomiting, Disturbance in attention, Palmoplantar keratoderma, Migraine, Tinnitus, Peripheral swelling, Pain of skin, Tension headache, Alopecia, Memory impairment, Sleep terror, Pruritus genital, Visual impairment, Diplopia, Blindness, Vasculitis, Transient ischaemic attack, COVID-19, Heart rate increased, Back pain, Muscle twitching, Hyperhidrosis, Rash papular, Dehydration, Anxiety, Carotid artery occlusion, Nausea, Myocardial infarction, Diabetes mellitus inadequate control, Product administration error, Incorrect product administration duration, Product use in unapproved indication, Off label use, Medication error,

CANDESARTAN, LANSOPRAZOLE, LANSOPRAZOLE, LANSOPRAZOLE, LANSOPRAZOLE, LANSOPRAZOLE, LANSOPRAZOLE, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, LEVOTHYROXINE, LEVOTHYROXINE, LEVOTHYROXINE, RAMIPRIL, RAMIPRIL, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, ISOSORBIDE MONONITRATE, ISOSORBIDE MONONITRATE, FUROSEMIDE, FUROSEMIDE, FUROSEMIDE, HYDROXYZINE, HYDROXYZINE, HYDROXYZINE, ZOLPIDEM TARTRATE, ZOLPIDEM TARTRATE, ZOLPIDEM TARTRATE, CITALOPRAM, CITALOPRAM HYDROBROMIDE, CITALOPRAM, CITALOPRAM HYDROBROMIDE, CITALOPRAM, CITALOPRAM HYDROBROMIDE, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, ALBUTEROL SULFATE, ALBUTEROL, ALBUTEROL SULFATE, ALBUTEROL, ALPRAZOLAM, ALPRAZOLAM, ALPRAZOLAM, METOCLOPRAMIDE, METOCLOPRAMIDE HYDROCHLORIDE, METOCLOPRAMIDE, METOCLOPRAMIDE HYDROCHLORIDE, METOCLOPRAMIDE, METOCLOPRAMIDE HYDROCHLORIDE, ALLOPURINOL, ALLOPURINOL, ALLOPURINOL, ALLOPURINOL, POTASSIUM CHLORIDE, POTASSIUM CHLORIDE EXTENDED-RELEASE, POTASSIUM CHLORIDE, DEXTROSE MONOHYDRATE, POTASSIUM CHLORIDE ORAL, POTASSIUM CHLORIDE, POTASSIUM CHLORIDE EXTENDED-RELEASE, POTASSIUM CHLORIDE, DEXTROSE MONOHYDRATE, POTASSIUM CHLORIDE ORAL, DABIGATRAN ETEXILATE, DABIGATRAN ETEXILATE, DABIGATRAN ETEXILATE, HYDROCHLOROTHIAZIDE, HYDROCHLOROTHIAZIDE, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE, METOPROLOL, SPIRONOLACTONE, SPIRONOLACTONE, POTASSIUM CHLORIDE, POTASSIUM CHLORIDE EXTENDED-RELEASE, POTASSIUM CHLORIDE, DEXTROSE MONOHYDRATE, POTASSIUM CHLORIDE ORAL, DEXTROSE MONOHYDRATE, DEXTROSE, FELODIPINE, FELODIPINE EXTENDED-RELEASE TABLETS, SIMVASTATIN, DAPAGLIFLOZIN, ESOMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM, BISOPROLOL FUMARATE, BISOPROLOL FUMARATE, BISOPROLOL FUMARATE, CETIRIZINE, CETIRIZINE HYDROCHLORIDE, CETIIRIZINE, CETIRIZINE, CETIRIZINE HYDROCHLORIDE, CETIIRIZINE, CETIRIZINE, CETIRIZINE HYDROCHLORIDE, CETIIRIZINE, CETIRIZINE, CETIRIZINE HYDROCHLORIDE, CETIIRIZINE, LINAGLIPTIN, APIXABAN, APIXABAN, APIXABAN, APIXABAN, APIXABAN, APIXABAN, ISOSORBIDE DINITRATE, ISOSORBIDE DINITRATE, ISOSORBIDE DINITRATE, ISOSORBIDE DINITRATE, ISOSORBIDE DINITRATE, ISOSORBIDE DINITRATE, DIGOXIN, DIGOXIN, DIGOXIN, DIGOXIN, DIGOXIN, NAPROXEN, NAPROXEN SODIUM, TORSEMIDE, VORTIOXETINE, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE,

25114694

SK

Syncope, Electrocardiogram QT prolonged, Dizziness, Asthenia, Fatigue, Drug interaction,

PROPAFENONE,

25115133

FR

Drug interaction, Iodine overload, Hyperthyroidism,

IODIXANOL, IODIXANOL,

25115340

CZ

Product administered to patient of inappropriate age, Drug interaction, Ileus paralytic, Petechiae,

RISPERIDONE, RISPERIDONE, RISPERIDONE, RISPERIDONE, RISPERIDONE, RISPERIDONE,

25115418

CN

Hepatocellular carcinoma, Drug level above therapeutic, Drug interaction, Prescribed underdose, Underdose,

REGORAFENIB, REGORAFENIB, REGORAFENIB, SIROLIMUS, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE,

25118134

Depression, Drug interaction, Sleep disorder, Loss of personal independence in daily activities,

LISDEXAMFETAMINE, LISDEXAMFETAMINE, DROSPIRENONE AND ETHINYL ESTRADIOL, BUPROPION HYDROCHLORIDE, BUPROPION, DEXTROAMPHETAMINE SACCHARATE, AMPHETAMINE ASPARTATE, DEXTROAMPHETAMINE SULFATE, AND AMPHETAMINE SULFATE, DEXTROAMPHETAMINE SULFATE, DEXTROAMPHETAMINE SACCHARATE, AMPHETAMINE SULFATE AND AMPHETAMINE ASPARTATE, DEXTROAMPHETAMINE SULFATE, DEXTROAMPHETAMINE SACCHARATE, AMPHETAMINE SULFATE AND AMPHETAMINE ASPARTATE, CALCIUM,

25109476

GB

Faeces discoloured, Haematemesis, Drug interaction,

CLOPIDOGREL BISULFATE, EDOXABAN TOSYLATE, ACETAMINOPHEN, ACETAMINOPHEN ORAL SOLUTION, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, DIPHENHYDRAMINE HCL, OSELTAMIVIR PHOSPHATE, FOLIC ACID, SIMVASTATIN, LEVOTHYROXINE, LANSOPRAZOLE,

25108273

DE

Generalised tonic-clonic seizure, Drug interaction, Electrocardiogram QT prolonged,

ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, FLUCONAZOLE, FLUCONAZOLE, QUETIAPINE, QUETIAPINE, QUETIAPINE, ENALAPRIL MALEATE, ENALAPRIL, LEVOTHYROXINE SODIUM, LEVOTHYROXINE SODIUM ANHYDROUS,

25108308

DE

Self-destructive behaviour, Mental disorder, Drug interaction,

SERTRALINE,

25108458

PL

Abdominal discomfort, Dyschezia, Defaecation disorder, Drug interaction, Drug ineffective,

AMLODIPINE, PREGABALIN, CALCIUM CARBONATE, DICLOFENAC, DICLOFENAC SODIUM, OXYCODONE,

25108618

PL

Drug interaction, Functional gastrointestinal disorder,

PREGABALIN, ASCORBIC ACID, FERROUS SULFATE, OXYCODONE,

25108639

US

Rhabdomyolysis, Malaise, Drug interaction, Nausea,

IXAZOMIB, DARATUMUMAB, DARATUMUMAB,

25108835

US

Seizure, Drug interaction,

RANOLAZINE, EXTENDED-RELEASE, PAROXETINE HYDROCHLORIDE HEMIHYDRATE, PAROXETINE, PAROXETINE HYDROCHLORIDE, NIFEDIPINE, RANOLAZINE, EXTENDED-RELEASE,

25108839

US

Drug interaction, Hypotension,

TIZANIDINE HYDROCHLORIDE, LISINOPRIL, METOPROLOL TARTRATE, METOROPROLOL TARTRATE, METOPROLOL, HYDRALAZINE HYDROCHLORIDE, HYDROCHLOROTHIAZIDE, LISINOPRIL, TIZANIDINE HYDROCHLORIDE,

25109131

US

Cushing^s syndrome, Product use in unapproved indication, Drug interaction,

TRIAMCINOLONE ACETONIDE, TRIAMCINOLONE ACETONIDE OINTMENT USP, 0.05%, DARUNAVIR, DARUNAVIR 600 MG, DARUNAVIR 800 MG, PREDNISOLONE ACETATE, FUROSEMIDE, AMIODARONE HYDROCHLORIDE, RITONAVIR, RITONAVIR 100 MG,

25109134

CN

Loss of consciousness, Drug interaction, Vomiting, Nausea, Incontinence, Hyperhidrosis, Restlessness, Pyrexia, Seizure,

CLINDAMYCIN PALMITATE HYDROCHLORIDE, SODIUM CHLORIDE, SODIUM CHLORIDE INJECTION, SODIUM CHLORIDE TABLET, NORMAL SALT TABLETS, CHOLIC ACID,

25102870

DE

Ataxia, Vision blurred, Diplopia, Dysarthria, Drug ineffective, Rebound effect, Epilepsy, Sedation, Drug interaction,

LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE, LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE, OXCARBAZEPINE, LACOSAMIDE, LACOSAMIDE, PHENOBARBITAL, PHENOBARBITAL, PHENOBARBITAL, PHENOBARBITAL, CARBAMAZEPINE, CARBAMAZEPINE, TOPIRAMATE, TOPIRAMATE SPINKLE, TOPIRAMATE, TOPIRAMATE SPINKLE, ZONISAMIDE, ZONISAMIDE, PHENYTOIN, PHENYTOIN, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES,

25102991

RO

Atrioventricular block complete, Ventricular tachycardia, Atrial tachycardia, Atrial flutter, Drug interaction,

METOPROLOL TARTRATE, METOPROLOL, DIGOXIN, LISINOPRIL, FUROSEMIDE, SPIRONOLACTONE,

25103042

JP

Rhabdomyolysis, Drug interaction,

POSACONAZOLE, POSACONAZOLE, POSACONAZOLE, ROSUVASTATIN CALCIUM, AMPHOTERICIN B, AMPHOTERICIN B, MAGNESIUM OXIDE,

25103436

FR

Subdural haematoma, Drug interaction,

DULOXETINE HYDROCHLORIDE, DULOXETINE, CANDESARTAN CILEXETIL, LANSOPRAZOLE, SIMVASTATIN, HYDROCHLOROTHIAZIDE,

25103506

US

Hypotension, Drug interaction,

TIZANIDINE HYDROCHLORIDE, LISINOPRIL, METOPROLOL TARTRATE, METOROPROLOL TARTRATE, METOPROLOL, HYDRALAZINE HYDROCHLORIDE, HYDROCHLOROTHIAZIDE,

25103580

CA

Depression, Loss of personal independence in daily activities, Off label use, Drug interaction,

ATAZANAVIR, CLONAZEPAM, LAMIVUDINE, LAMIVUDINE ORAL, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, SERTRALINE, VALPROIC ACID, BUPROPION HYDROCHLORIDE, LOPINAVIR AND RITONAVIR, ENFUVIRTIDE,

25103645

DE

Drug ineffective, Sedation, Vision blurred, Diplopia, Ataxia, Dysarthria, Drug interaction,

TOPIRAMATE, TOPIRAMATE, PHENYTOIN, PHENYTOIN, LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE, LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE, PHENOBARBITAL, PHENOBARBITAL, PHENOBARBITAL, PHENOBARBITAL, LACOSAMIDE, LACOSAMIDE, ZONISAMIDE, ZONISAMIDE, LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, OXCARBAZEPINE, OXCARBAZEPINE, CARBAMAZEPINE, CARBAMAZEPINE, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES,

25103897

US

Arteriospasm coronary, Drug interaction,

ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, SUMATRIPTAN, SUMATRIPTAN SUCCINATE,

25104352

US

Adverse drug reaction, Treatment noncompliance, Dizziness, Drug interaction,

LISINOPRIL,

25104984

PL

Epilepsy, Drug interaction, Drug level below therapeutic, Drug ineffective,

LEVETIRACETAM, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM IN SODIUM CHLORIDE, LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, DABIGATRAN ETEXILATE, TOPIRAMATE, TOPIRAMATE SPINKLE, ROSUVASTATIN, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG,

25105123

US

Toxicity to various agents, Drug interaction,

APIXABAN, LACOSAMIDE,

25106209

US

Hysterectomy, Hot flush, Aggression, Product dose omission issue, Drug interaction, Off label use,

LEVOKETOCONAZOLE, ESTRADIOL,

25106294

IT

Drug interaction, Gastric haemorrhage, Melaena, Discoloured vomit, Dyspnoea, Pallor, Pleural effusion, Anaemia,

FLUCONAZOLE, DABIGATRAN ETEXILATE MESYLATE, DABIGATRAN ETEXILATE, DUTASTERIDE, AMLODIPINE BESYLATE, ALLOPURINOL, URSODIOL, URSOSIOL, CALCITRIOL,

25106498

Drug interaction,

METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS,

25106521

ES

Non-cardiogenic pulmonary oedema, Drug interaction, Toxicity to various agents,

VENLAFAXINE, VENLAFAXINE HYDROCHLORIDE, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), ZOLPIDEM TARTRATE, CLONAZEPAM, QUETIAPINE, QUETIAPINE EXTENDED-RELEASE, PROPOFOL, ALPRAZOLAM, FENTANYL,

25106575

DE

Heavy menstrual bleeding, Pneumonitis, Deafness, Drug interaction, Depression, Epstein-Barr virus infection, Asthma, Pain in extremity, Arthralgia, Eructation, Endocrine disorder, Parosmia, Post-acute COVID-19 syndrome, Ear inflammation, Temperature intolerance, Withdrawal syndrome, Smoke sensitivity, Inflammation, Viral infection, Drug intolerance, Sensitivity to weather change, Premenstrual syndrome, Infection, Painful respiration, Hormone level abnormal, Nasal inflammation, Product dose omission in error, Drug ineffective,

FLUTICASONE PROPIONATE, ALBUTEROL SULFATE, ALBUTEROL, HYDROCORTISONE,

25107128

DE

Renal impairment, Blood creatine phosphokinase increased, Myalgia, Transaminases increased, Product use issue, Drug interaction,

DAROLUTAMIDE, ROSUVASTATIN CALCIUM, ROSUVASTATIN CALCIUM,

25107344

US

Emergency care, Rhabdomyolysis, Drug ineffective for unapproved indication, Adverse event, Off label use, Drug interaction,

DARATUMUMAB, BORTEZOMIB, IXAZOMIB,

25097245

CA

Hospitalisation, Brain neoplasm, Somnolence, Drug interaction,

CANNABIDIOL,

25097415

CN

Bradycardia, Drug interaction, Hypotension,

METOPROLOL TARTRATE, METOPROLOL, IVABRADINE,

25097579

CN

Hypovolaemia, Rhythm idioventricular, Bradycardia, Hypotension, Drug interaction, Contraindicated product administered,

IVABRADINE, METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, DILTIAZEM HYDROCHLORIDE, DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE TABLETS,

25097868

US

Mental status changes, Multiple drug therapy, Drug interaction, Hepatic enzyme increased, Asthenia,

DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), ACETAMINOPHEN AND CODEINE, NIRMATRELVIR AND RITONAVIR, NYSTATIN, NYSTATIN OINTMENT, NYSTATIN CREAM, GABAPENTIN, ALBUTEROL SULFATE, BISOPROLOL FUMARATE, MAGNESIUM OXIDE, TIOTROPIUM BROMIDE,

25097879

US

Pancreatitis, Toxicity to various agents, Duodenitis, Gastritis, Drug interaction,

COLCHICINE, COLCHICINE, ERYTHROMYCIN, CYCLOSPORINE, PREDNISONE,

25097898

FR

Cardiac disorder, Labelled drug-drug interaction issue, Drug interaction,

BISOPROLOL FUMARATE,