Drugs That Can Cause Depression, Agitation & Suicidality

Depressed young man. Suicide concept

Author: RxISK Medical Team

Last updated: 2018

Life expectancy is falling or has stopped rising in Western and other developed countries. In some countries (USA) rising suicide rates have been highlighted as one possible factor in this fall.

In others (UK) the suicide rate doesn’t appear to be rising but it’s difficult to get a clear picture because unless people openly declare they are suiciding, coroners have been encouraged to return open verdicts, death by misadventure verdicts, or narrative verdicts.

Many people who have had a loved one made suicidal by a medication welcome verdicts like these as recognizing to some extent it was an external factor that caused the death rather than their child’s, parent’s or partner’s intention to take their own lives. The upshot however is we have no idea what the true rate of medication-induced suicide is. It is almost certainly rising in countries other than the United States as well.

What risks can medications cause?

Prescription medicines from antibiotics to contraceptives can increase your risk of suicide by triggering:

  • a depressive or dysphoric state
  • anxiety
  • agitation or akathisia
  • disinhibition
  • psychosis or delirious states

What medications might put you at risk?

We have compiled a list of over 350 individual medicines that cause problems. Most of these drugs are marketed under many different trade names, sometimes hundreds of different trade names when language variations are taken into account. Many are marketed in combination with other medicines – sometimes with 3 or 4 or more medicines bundled into the same pill – with the result that you may not realize what drugs you are taking. The labeling of these drugs can differ across countries, with some labels revealing the risks in the very small print, and labels from other countries not revealing the risks from the same drug.

In total there are 40,000 or more different trade named drugs in North America and Europe that can make you depressed, agitated or suicidal. Roughly 20% of the named drugs on the market in any one country may pose risks to you. Roughly 33% of us are taking one of them.

The risk comes from the drug, not you. The difficulty in seeing this comes from the fact that we are all different. A drug that makes one person feel better, slows their heart rate or lowers their cholesterol, may make their friend suicidal, increase their heart rate or increase cholesterol levels. Companies trade on this – they sell the average headline effect of their drug as its only effect. If something else happens to you that’s an anecdote, or suggests you have another disease or even that you’ve fabricated things.

Astonishingly, companies get away with this. Even though the depression, anxiety, or suicidality that you are experiencing is written into the label of the drug you are on, your doctor may completely deny that this is a possibility when it seems obvious to you. Or just as bad, s/he may never point out to you that the symptoms you are having that you don’t connect to the drug, may in fact stem from this source. S/he will instead likely add in more drugs which will almost certainly make the problem worse.

As a recent article in JAMA showed, the more drugs you are on, the greater the risk you run. Taking three or more drugs that can cause a problem triples your risk of being dysphoric, akathisic, or suicidal.

Over 50% of us of all ages are on at least one drug and 50% over 45 are on at least three drugs, and 40% of over 65s are on five drugs or more.

There are variations in the risks these drugs pose. Being on a cocktail of drugs that includes a proton pump inhibitor (PPI) for acid reflux dramatically increases your risks, as do some anti-infectives like Lariam or fluoroquinolone antibiotics, whereas while statins are highly likely to cause fatigue they are less likely to cause suidicality or homicidality.

It is increasingly common for anyone taking a psychotropic drug, especially in America, to be on three or more psychotropics. If you are on three or more psychotropics, it is more likely than not that a significant part of your nervous problems stem from your medication.

The worry with psychotropic drugs is that by the time you read this, you may be close to or past the point of no return – getting back to a point where your medication is not causing your problem may be difficult.

How have we compiled this list?

Some drugs on the list come with explicit warnings of suicide – drugs for skin disorders and antidepressants.

Others such as anticonvulsants and mood-stabilizers show increased risks of akathisia and suicidality in clinical trials – equivalent to risks from skin drugs and antidepressants – but companies have dodged the requirement to warn.

The most common source of information comes from further down the label where companies describe other side effects that have been reported to them, for example by patients and doctors. Most doctors and other folk reading this will read:

“Whaddya know, a bunch of freaks have contacted us and told us our drug causes depression, agitation, psychosis, suicidality or homicidality. In the interests of transparency we are including these reports on the label but of course no causal connection has been made.”

However, these reports of depression, agitation, psychosis, suicidality or homicidality are put in the labels of drugs only where the company has investigated the case in great detail and can find no other way to explain the problem other than it was caused by their drug.

If it happens to you

These problems can happen when starting, stopping and changing the dose of a drug.

They can happen straight away – within an hour of your first dose or any change of dose – or they can take weeks to appear. Depression builds up slowly, agitation is quicker to appear.

If you develop a nervous problem, some drug you are on is probably the single likeliest cause. Your “mental” problems may even stem from the eye-drops you are using.

No-one should assume that if someone is taking a drug for a mental issue, a suicide or breakdown stems from their “illness”. Suicides are more likely in those on drug treatment for mental disorders than in those not taking medicines.

The greatest difficulty lies in knowing what to do if you suspect a treatment is causing you, or your partner or a child, problems.

Something curious that no-one properly understands can happen to those affected that can be seen even with something like coffee. Taking too much strong coffee can give any of us palpitations or make us agitated. Even as one part of us tells us not to take any more, another can figure that another cup of coffee would be good.

This is quite like what happens with food leading to bulimia and may apply to many things that make us feel worse. We’d love a good explanation of this phenomenon if anyone out there has one.

If your treatment is making you worse, your doctor may or may not be a good person to turn to. Doctors’ understanding that treatments can cause problems like this is shaky. There is at least a 50-50 chance their advice will be to stay on treatment or even increase the dose – the wrong advice if treatment is causing the problem.

If you are convinced the drug is your problem or your partner’s problem, the best advice is to lower the dose and perhaps stop treatment. If things improve over time, this is an important pointer to the role of treatment.

If the problem has appeared on withdrawal of some drug, the best advice may be to reinstate treatment and see what happens.

The list

Acid & reflux

Generic NameTrade Names
Cimetidine
Tagamet & 40 others
DexlansoprazoleDexilent
Esomeprazole
Nexium & 600 others
Famotidine
Pepcid & 100 others
Lansoprazole
Zoton, Prevacid & 300 others
Nizatidine
Axid
Omeprazole
Losec, Prilosec & 700 others
Pantoprazole
Protonix & 800 others
Rabeprazole
Aciphex, Pariet & 200 others
Ranitidine
Zantac & 400 others

Analgesics

Opioid analgesics

Generic NameTrade Names
AlfentanilAlfenta & 30 others
BuprenorphineSubutex & 400 others
CodeineCodeine & 300 others
DextropropoxypheneDiclofenac & 20 others
DiamorphineHeroin & 15 others
FentanylActiq & 400 others
Hydrocodone & combinationsVicodin & 90 others
Hydromorphone & combinationsExalgo & 90 others
Methadone & combinationsMethadose, Dolophine & 140 others
Morphine & combinationsAvinza, Oramorph, MS Contin & 300 others
NalbufeneNalpain & 20 others
NalmofeneSelenero
Naloxone & combinationsNarcan & 200 others
NaltrexoneVivitrol & 80 others
Oxycodone & combinationsOxycontin, Percocet & 450 others
PethidineDemerol & 50 others
PropoxypheneDarvon

Psychotropic analgesics

Generic NameTrade Names
AmitriptylineElavil, Tryptizol & 100 others
CarbamazepineTegretol & 120 others
DuloxetineCymbalta & 400 others
GabapentinNeurontin & 300 others
LamotrigineLamictal & 200 others
NortriptylineAllegron, Aventyl & 40 others
OxcarbazepineTrileptal & 80 others
PregabalinLyrica & 250 others
TopiramateTopamax & 220 others

Triptan analgesics

Generic NameTrade Names
AlmotriptanAlmogen Axen & 66 others
EletriptanRelpax & 60 others
FrovatriptanFrova & 50 others
NaratriptanAmerge & 60 others
RizatriptanMaxalt & 150 others
SumatriptanImitrex & 250 others
ZolmatriptanZomig & 200 others

Older analgesics

Generic NameTrade Names
BaclofenLioresal & 120 others
CarisoprodilSoma
ChlorzoxazoneLorzone, Parafon
CyclobenzaprineFlexeryl & 5 others
MethocarbamolRobaxin
MetaxoloneSkelaxin
TizanidineZanaflex & 30 others

Anti-asthma

Generic NameTrade Names
MontelukastSingulair & 500 others
RoflumilastDaxas
ZafirlukastAccolate & 8 others

Anti-acne

Generic NameTrade Names
AcitretinSoriatane, Neotigason & 50 others
AlitretinoinToctino & 20 others
DoxycyclineDoryx & 250 others
IsotretinoinAccutane, Ro-Accutane & 130 others
TretinoinRetin A & 40 others

Anti-arrhythmic drugs

Generic NameTrade Names
FlecainideTambocor & 80 others
PropafenoneRhythmol & 90 others

Anti-clotting drugs

Generic NameTrade Names
ClopidogrelPlavix & 400 others

Anticonvulsants

Generic NameTrade Names
CarbamazepineTegretol & 100 others
EthosuximideEmeside, Zarontin & 25 others
FelbamateFelbatol & 25 others
GabapentinNeurontin & 300 others
LacosamideVimpat & 120 others
LamotrigineLamictal & 200 others
Levetiracitam Keppra & 400 others
OxcarbazepineTrileptal & 80 others
PhenytoinEpanutin & 100 others
PregabalinLyrica & 250 others
Sodium valproateDepakene, Epilim & 200 others
TiagabideGabitril & 10 others
TopiramateTopamax & 220 others
VigabatrinSabril & 20 others
ZonisamideZonergan & 130 others

Anti-dementia

Generic NameTrade Names
DonepexilAricept & 400 others
GalantamineRazadyne &160 others
MemantineNamenda & 100 others
RivastigmineExelon & 300 others

Antidepressants

Serotonin reuptake inhibitors

Generic NameTrade Names
Citalopram
Celexa, Cipramil & 400 others
DapoxetinePriligy & 30 others
Desvenlafaxine
Pristiq, Enzude
Duloxetine
Cymbalta & 400 others
Escitalopram
Cipralex, Lexapro & 600 others
Fluoxetine
Prozac & 300 orthers
Fluvoxamine
Faverin, Luvox & 50 others
LevomilnacipranFetzima
MilnacipranIxel, Savella & 10 others
Paroxetine
Paxil, Seroxat & 300 others
Sertraline
Zoloft & 400 others
Venlafaxine
Effexor & 500 others
VortioxetineBrintellix, Trintellix

Tricyclic antidepressants

Generic NameTrade Names
Amitriptyline
Elavil, Tryptizol & 100 others
Amitriptyline & chlordiazepoxideLimbitrol & 10 others
Amitriptyline & perphenazineTriptafen & 5 others
Clomipramine
Anafranil & 70 others
Desipramine
Norpramin, Pertofran
DosulepinProthiaden
DoxepinSinequan & 30 others
Imipramine
Tofranil & 20 others
LofepramineGamanil
Nortriptyline
Allegron, Aventyl & 40 others
ProtriptylineVivactil
TrimipramineSurmontil & 25 others

Other antidepressants & anxiolytics

Generic NameTrade Names
BuproprionWellbutrin & 80 others
BuspironeBuspar & 50 others
MianserinTolvon & 30 others
Mirtazepine
Remeron & 300 others
MoclobemideAurorix & 50 others
NefazodoneSerzone
PhenelzineNardil & 5 others
SelegileneEldepryl & 50 others
TranylcypromineParnate & 10 others
Trazodone
Desyrel, Molipaxin & 80 others
VilazodoneViibryd

Antihistamines

Generic NameTrade Names
CetirizineZyrtec & 250 others
ChlorphenamineChlortimeton, Piriton & 200 others
CyproheptadinePeriactin & 10 others
DexchlorpheniraminePolaramine & 10 others
DiphenhydramineBenadryl, Sominex & 800 others
FexofenadineAllegra & 100 others
LevocetirizineAlcet, Clarigen & 200 others
Pyrilamide
Mepyramine
Antihistan & 20 others

Antihypertensives

ACE inhibitors

Generic NameTrade Names
BenazeprilLotensin & 20 others
CaptoprilCapoten & 190 others
CilazaprilDynorm & 30 others
EnalaprilVasotex & 600 others
FosinoprilMonopril & 130 others
LisinoprilZestril & 300 others
MoexiprilUnivasc & 5 others
PerendiprilCoversyl & 500 others
QuinaprilAccupril & 90 others
RamiprilLopace, Tritace & 400 others
TrandolaprilGopten & 50 others

Beta-blockers

Generic NameTrade Names
AcebutalolSectral & 40 others
AtenololTenormin & 200 others
BambuterolBambec & 30 others
BetaxololKerlone & 90 others
BisoprololZebeta & 500 others
CarvedilolCoreg & 200 others
CeliprololCordiax & 30 others
LabetalolTrandate & 50 others
MetoprololLopressor, Toprol & 400 others
NadololCorgard & 5 others
NebivololAsivol & 250 others
PindololVisken & 10 others
PropranololInderal & 80 others
SotalolBetapace

Older antihypertensives

Generic NameTrade Names
ApraclonidineLopidine & 15 others
ClonidineCatapres & 50 others
DoxazosinCardura & 250 others
Guanabenz Wytensin & 5 others
GuanfacineTenex & 4 others
HydralazineApresoline & 20 others
MethyldopaAldomet & 30 others
PrazosinMinipress & 15 others
RauwolfiaRauwolfia & 20 others
ReserpineSerpasil & 20 others

Anti-Infectives

Antibiotics & anti-protozoals

Generic NameTrade Names
CycloserineSeromycin & 15 others
DapsoneAczone & 10 others
DoxycyclineVibramycin, Doryx & 250 others
LymecyclineLimeclin, Tetralysal & 30 others
MefloquineLariam & 13 others
MetronidazoleFlagyl & 350 others
TafenoquineKristafel

Antivirals

Generic NameTrade Names
AbacavirEpzicom & 10 others
Abacavir & lamiduvineKivexa, Zentiva & 140 others
AtazanavirReyataz & 30 others
EfavirenzSustiva & 60 others
Efavirenz, emtricitabine & othersAtripla & 200 others
EmtricitabineEmtriva & 200 others
LamiduvineEpivir & 50 others
OseltamivirTamiflu & 10 others
RaltegravirIsentress & 15 others
RibavirinRebetol, Copegus & 90 others
ZanamavirRelenza & 20 others

Fluoroquinolone antibiotics

Generic NameTrade Names
CiprofloxacinCipro & 600 others
GamifloxacinFactive
LevofloxacinLevaquin & 600 others
LomefloxacinMaxaquin & 5 others
MoxifloxacinAvelox & 350 others
NorfloxacinNoroxin & 80 others
OfloxacinFloxin & 160 others

Anti-nausea

Generic NameTrade Names
DronabinolSativex
GranisetronKytril & 10 others
MetoclopramideMaxolon, Reglan & 180 others
OndansetronZofran & 450 others
ProchlorperazineCompazine, Stemetil & 30 others

Anti-psoriasis

Generic NameTrade Names
AdalimumabHumira & 9 others
ApremilastOtezla
BrodalumabSiliq, Kyntheum
IsekizumabTalzt
UstekizumabStelara

Antipsychotics

Antipsychotics pre-1990

Generic NameTrade Names
BenperidolAnquil & 5 others
ChlorpromazineLargactil, Thorazine & 50 others
ChlorprothixeneTruxal & 30 others
ClozapineClozaril & 100 others
DroperidolDroleptan & 50 others
FlupenthixolDepixol, Fluanxol & 50 others
FluphenazineModecate, Prolixin & 20 others
FlusprileneImap & 4 others
HaloperidolHaldol, Serenace & 130 others
LevomepromazineNozinan & 50 others
MelperoneBuinil & 20 others
MolindoneMoban
PericiazineNeulactil & 5 others
PerphenazineFentazin, Trilafon & 10 others
PimozideOrap & 10 others
PipamperoneDiperone & 10 others
SulpirideDolmatil, Sulpitil & 80 others
TetrabenazineXenazine & 30 others
ThiothixeneNavane
TrifluoperazineStelazine & 15 others
ZuclopenthixolClopixol & 50 others

Antipsychotics post-1990

Generic NameTrade Names
AmisulpirideSolian & 130 others
Aripiprazole
Abilify & 500 others
AsenapineSaphris, Sycrest
BrexipiprazoleRexulti
CariprazineVraylar
DeutetrabenazineAustedo
IloperidoneFanapt
LoxapineLoxapac & 5 others
LurasidoneLatuda & 5 others
Olanzapine Zyprexa & 450 others
Paliperidone
Invega & 30 others
PimavanserinNuplazid
Quetiapine Seroquel & 700 others
RisperidoneRisperdal & 400 others
SertindoleSerdolect & 20 others
ValbenazineIngrezza
Ziprasidone
Geodon & 100 others
ZopetineZoleptil & 5 others

Anti-smoking & anti-alcohol

Generic NameTrade Names
AcamprosateCampral & 20 others
BaclofenLioresal & 120 others
BuproprionZyban & 100 others
VareniclineChantix, Champix

Anxiolytics (tranquilizers)

Benzodiazepines

Generic NameTrade Names
AlprazolamXanax & 200 others
ChlordiazepoxideLibrium & 30 others
ClobazamFrisum & 40 others
ClonazepamKlonopin, Rivotril & 50 others
ClorazepateTranxene & 20 others
DiazepamValium & 250 others
LorazepamAtivan & 120 others
MedazepamNobrium & 10 others
Oxazepam Serenid, Serax & 60 others

Beta-blockers

Generic NameTrade Names
AcebutalolSectral & 40 others
AtenololTenormin & 200 others
BambuterolBambec & 30 others
BetaxololKerlone & 90 others
BisoprololZebeta & 500 others
CarvedilolCoreg & 200 others
CeliprololCordiax & 30 others
LabetalolTrandate & 50 others
MetoprololLopressor, Toprol & 400 others
NadololCorgard & 5 others
NebivololAsivol & 250 others
PindololVisken & 10 others
PropranololInderal & 80 others
SotalolBetapace

Niche anxiolytics

Generic NameTrade Names
ApraclonidineLopidine & 15 others
ClonidineCatapres & 50 others
DoxazosinCardura & 250 others
Guanabenz Wytensin & 5 others
GuanfacineTenex & 4 others
HydralazineApresoline & 20 others
MethyldopaAldomet & 30 others
PrazosinMinipress & 15 others
RauwolfiaRauwolfia & 20 others
ReserpneSerpasil & 20 others

Serotonergic

Generic NameTrade Names
Citalopram
Celexa, Cipramil & 400 others
DapoxetinePriligy & 30 others
Desvenlafaxine
Pristiq, Enzude
Duloxetine
Cymbalta & 400 others
Escitalopram
Cipralex, Lexapro & 600 others
Fluoxetine
Prozac & 300 orthers
Fluvoxamine
Faverin, Luvox & 50 others
LevomilnacipranFetzima
MilnacipranIxel, Savella & 10 others
Paroxetine
Paxil, Seroxat & 300 others
Sertraline
Zoloft & 400 others
Venlafaxine
Effexor & 500 others
VortioxetineBrintellix, Trintellix

Cancer therapies

Breast cancer drugs

Generic NameTrade Names
AnastrozoleArimidex & 340 others
ExemestaneAromasin & 200 others
RaloxifeneEvista
TamoxifenNolvadex, Tamifen & 120 others

Prostate cancer drugs

Generic NameTrade Names
BicalutamideCasodex & 340 others
GoserelinZoladex & 60 others
LeuporelinLupron & 130 others

Other cancer drugs

Generic NameTrade Names
ErlotinibTarceva
LenalidomideRevlimid
SorfanibNexavar
ThalidomideThalomid

Contraceptives

Generic NameTrade Names
ChlormadinoneBelara & 80 others
Conjugated estrogensPremarin & 15 others
Cyproterone & estradiolDiane, Dianette & 90 others
Desorgestrel & combinationsAzurette & 450 others
DienogestEstradiol valerate & 300 others
DihydrogesteroneFemoston & 80 others
DrospirenoneYasmin, Yaz & 800 others
Estradiol & combinationsEstrogel & 400 others
Estriol Ovestin & 100 others
EstropipateHarmogen & others
EthinylestradiolAlesse & 800 others
EtonorgestrelCirclet, NuvaRing & 20 others
HydroxyprogesteroneDilalutin & 4 others
LevonorgestrelEllaOne & 300 others
MedroxyprogesteroneDepo-Provera & 80 others
MegesterolMegace & 35 others
NorethisteronePrimolut nor & 120 others
NorgestrolOvrette & 16 others

Disease modifying agents

Generic NameTrade Names
CyclosporineNeoral, Sandimmune & 10 others
DalfampridineAmypyra
Dimethyl fumarateTecfidera
FingolimodGilenya
GlatiramerCopaxone
Interferon beta 1aAvonex, Rebif & 5 others
Interferon beta 1bBetaferon, Betaseron
MethotrexateTrexall & 99 others
NatalizumabTysabri
Peg-InterferonCopegus, Rebetol & 5 others
TeriflunomideAubagio

Dopamine agonists

Generic NameTrade Names
AmantadineOsmolex, Symmetrel & 50 others
ApomorphineApokine, Uprima & 100 others
BromocriptineParolodel & 50 others
Cabergoline
Dostinex & 70 others
Carbidopa & combinationsSinemet & 240 others
Entacapone & combinationsComtan & others
Levodopa & combinationsBenseride & 80 others
PergolidePermax & 5 others
PramipexoleMirapex & 250 others
Quinagolide
Norprolac & 25 others
RasagilineAzilect & 300 others
Ropinirole
Requip & 250 others
RotigotineNeupro & 19 others
Tolcapone & combinationsTasmar & others

Endometriosis

Generic NameTrade Names
BuserelinSuprecur & 30 others
GoserelinZoladex & 60 others
LeuporelinLupron & 120 others
NaferelinSynarel & 80 others
TriptorelinGonapeptyl &120 others

Hypnotics

Generic NameTrade Names
ButabarbitalButisol
ChlormethiazoleHeminevrin & 15 others
EszopicloneLunesta
FlunitrazepamDalmane & 30 others
FlurazepamRohypnol & 12 others
Lormetazepam Noctamid & 80 others
NitrazepamMogadon & 60 others
PentobarbitalNembutal & 80 others
QuazepamDoral, Quiedorm
RamelteonRozerem
SuvorexantBelsomra
TemazepamNormison & 30 others
TriazolamHalcion & 20 others
ZaleplonMorfeo
ZolpidemAmbien & 240 others
ZopicloneZimovane & 140 others

Menopausal

Generic NameTrade Names
CinacalcetMimpara, Sensilar
FluoxetineSarafem
ParoxetineBrisdelle
RaloxifeneEvista

Mood stabilizers

Generic DrugTrade Names
CarbamazepineTegretol & 160 others
GabapentinNeurontin & 300 others
LamotrigineLamictal & 200 others
OxcarbazepineTrileptal & 80 others
PregabalinLyrica & 250 others
Semi-sodium valproateDepakote & 4 others
TiagabideGabitril & 10 others
TopiramateTopamax & 220 others
Valproic acidDivalproex sodium & 80 others
ValpromideDepamide

Statins

Generic NameTrade Names
Atorvastatin
Lipitor & 700 others
Fluvastatin
Lescol & 200 others
Lovastatin
Mevacor & 60 others
PitavastatinLivalo & 20 others
PravastatinPravachol & 230 others
Rosuvastatin
Crestor & 600 others
SimvastatinZocor & 700 others

Steroids

Generic NameTrade Names
BudesonidePulmicort & 90 others
DexamethasoneDecadron & 400 others
HydrocortisoneCorlef & 100 others
MethylprednisoloneMedrol & 200 others
Prednisolone/PrednisoneDeltasone & 240 others
TriamcinoloneKenacort & 50 others

Anabolic steroids

Generic NameTrade Names
CyproteroneAndrocur & 20 others
NandroloneDynabolon & 10 others
OxandroloneOxandrin & 10 others
TestosteroneSustanon & 200 others

Stimulants

Generic NameTrade Names
AmphetamineAdderal & 20 others
ArmodafanilNuvigil
AtomoxetineStrattera & 100 others
DexamphetamineDexedrine & 20 others
Dexamphetamine slow releaseRexall & 10 others
DexmethylphenidateFocalin & 10 others
LisdexamphetamineVyvanse & 15 others
MethylphenidateRitalin, Inspiral, Addwize, Aptensio, Biphentin, Equasym & 200 others
Methylphenidate slow releaseConcerta, Metadate ER
ModafanilProvigil & 50 others
Sodium oxybateXyrem & 10 others

Unlikely

The headline drugs here likely do not cause a problem but they are commonly combined with drugs that can.

Generic NameTrade Names
AmolidipineCombined with statins, beta-blockers & ACE inhibitors
AspirinCombined with beta-blockers & ACE inhibitors
DextromethorphanCombined with opioids, antihistamines & analgesics in over 50 products
BendroflumethiazideCombined with beta-blockers & ACE inhibitors
HydrochlorthiazideCombined with beta-blockers & ACE inhibitors
Vitamin D / cholecalciferolCombined with many biphosphonates

Urinary flow

Generic NameTrade Names
DuloxetineYentreve & 100 others
DutasterideAvodart & 300 others
FinasteridePropecia, Proscar & 400 others
TamsulosinFlomax & 400 others

Weight loss

Generic NameTrade Names
Buproprion & naltrexoneContrave
LorcaserinBelviq
SibutramineMeridia
Topiramate & phentermineQsymia

Xeno-pharma

There are probably a large number of drugs used only in African or Asian settings that have not made it on to the radar elsewhere. We would appreciate any information you hear about.

Generic NameTrade Names
InvermectinStromectol