Roche and The Perfect Circle

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December 19, 2016 | 45 Comments

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  1. Heather, I really admire the spirit in which you and David work toward getting the word out about RoAccutane and the other drugs that affected Ollie. When I read your last post, I was overcome by how badly your family was treated, and for so long. There are patterns with these companies and their drugs and the history of RoAccutane looks somewhat like that of benzodiazepines: people had concerns early on and were ignored, harms kept occurring over many years and were/are denied, companies won’t change and no one can make them. I guess SSRIs and god knows how many others have a similar history.

  2. Thanks so much Laurie. I feel now that there must be a better way of treating acne satisfactorily, and for as long as RoAccutane-isotretinoin is there, more research will not be done. I am no scientist, but I do have a few ideas I’d like to air here, for others more expert in this field to comment on:
    Point 1: could there be two very different kinds of reactions in individuals to acne, and therefore, should we be looking at at least two different ways of healing it?
    —the young person going through puberty, with changing hormones, may well get a scattering of spots every so often, which could be treated with good skin hygiene, not too much washing to dry out oiliness, but keeping it clean and trying not to touch it with oily hands etc. also watching whether certain foods make the spots worse. Trying not to worry about it too much, being aware that this is likely to be a phase lots of us go through, and it will pass.
    —-then there are those like Olly and me who seem to get really very severe acne, erupting into painful boils and lesions one after another, particularly on the back, neck and chest. To look at Olly’s face, you would never guess what his back and chest were like. This acne did not pass away with puberty. He tried literally everything he could get his hands on, to make it go. Until he resorted to RoAccutane- isotretinoin, and even that didn’t really make much difference to his skin, lastingly, but sadly, it sure did mess his mind up, and his joints, and his liver, and his gut, and his muscles, and his eyes, and his hair, and plenty more besides.

    if we look at his early history, we see a baby born by Caesarean section, having been kept from miscarrying by his mum having regular shots of progesterone through the pregnancy and having to rest up for months, the last month in hospital. He could only digest breast milk, and stayed on that for a year. Cows’ milk and soya gave him terrible colic. Aged 5 he became asthmatic. He was a worrier, but at the same time, a loving, cheerful and kind child. Age 7 he was tested for coeliac disease and was shown to have a leaky gut. Age 9 he was caught in crop spray, and became sensitive to organo- phosphates on our sheep farm, having CFS for several years, but never missing school, being of a rather determined non-attention seeking disposition and not wanting to stand out from the crowd. He was still a worrier, but hid it well. Age 14 the acne began, with a vengeance. The only thing that drove it away was following the Stone Age diet. This was rubbished by his dermatologist, so he stopped it. He always loved to drink a glass of cold milk, straight from the fridge.

    Could we surmise that Olly’s kind of acne was gut related? So, by shutting down the outlets on the skin for oily sebum, he could not get rid of it any other way. If his leaky gut in addition meant that food escaped also into the blood, and didn’t go out through the digestive process, shutting things down was probably not a good idea.So perhaps it was trying to get out via the skin, hence the boils and lesions. Add to this, if he did not have the CYP450 enzyme, he could not detoxify anything, including medicines easily.

    Once onto the RoAccutane- isotretinoin, which works by closing down skin, hormones, affecting DNA, he would be in a gridlock where the only place for toxins to go would be to cross the blood brain barrier and cloud his rational thinking. Add to this the perpetual worry about having such ugly skin, with no prospect of improvement, and you are into a downward spiral. I would love to know what was in the powders or pills the homeopath used when Olly was about 17, (but the practitioner wouldn’t tell us) as maybe they introduced some kind of bacteria, or sulphur. It made such an amazing worsening, that we were extremely surprised. We asked for an antidote but apparently there wasn’t one! It was supposed to get worse and then better, but it just got worse and worse and worse!

    I feel we need to get school biology departments involved, doing their own research. They must not be Pharma funded. They are best placed to test out what foods, lifestyles etc work, maybe taking weekly ‘selfies’ and comparing their individual results. It would be fantastic if those who wanted to could have the saliva test for CYP450. It would be even more fantastic if they could crack the code of acne in all its forms, and themselves earn the funding from the State (which we think at one point Earl Howe said was on offer) to change lives, and make Roche’s RoAccutane-isotretinoin a thing of the past. They could save so many like Olly in the process. Any ideas on how we could propose this without Big Pharma interference? Any biology teachers out there interested to set up a trial. Obviously not to include antibiotics or RoAccutane, but anything natural and safe that could help. The Universities can’t/won’t do it because so many of their research labs are Pharma funded. Over to you….

  3. Dear David and Heather,
    I am very proud of you and other parents confronting these powerful organizations.
    Many parents are grieving and they need to be very sensitive in how they approach these meetings.
    I was very shocked when I read that:
    Another source suggests all prescriptions containing isotretinoin have risen from 1,687 in 2008 to 48,797 in 2012. ~ This is very worrying!
    I believe that a lot of meds can permanently damage brain tissue however, what are pharmaceutical companies doing??? Washing their hands of any accountability.
    This is not ethical business.
    These acne medicines should come with a warning, also.
    I have spoken to many young people regarding this medication and many have had unfavourable outcomes. Some suffer from multiple allergies whilst others generally feel down.
    The same lame excuses pharmaceutical companies have to offer is:
    ‘ This drug has no proven causal link with suicide’ disclaimer, and said they take the safety of medicines very seriously’.
    If this is the case, MHRA/FDA and whoever else is involved, have failed their duty of care.
    They are putting profits before people and I am certain that it will come back to bite them in the proverbial – (excuse the language!)
    There are enough people grieving out there as a result of these meds ruining the good minds of their loved ones.
    If the MHRA/ FDA want to speak with me, I have no shame in telling them how I cope on a day to day basis, from having ingested a med that they deem as safe.
    To understand how these people feel, one has to walk in their shoes and REFRAIN from using the same old lame excuses, year after year.
    People have been maimed and died as a result of ingesting these meds and they are demanding CHANGES so that no one else has to suffer the same fate.
    I am humbled by what you and many other parents are doing to create an awareness regarding this dubious med.
    I am sorry that beautiful Olly and others have had to suffer unnecessarily.
    If RoAccutane – isotretinoin, is used to shrink brain and pancreatic tumours and the clinical results have been favourable, let it treat what it was originally intended for.
    You are on a mission Heather and David. I am glad you have likeminded people support you with your mission. Having someone to lobby for you is an extraordinary gift.
    You may not see the results of what you want to achieve now however, I have faith, trust and believe that all your prayers will be answered very soon.
    Keep up the great work!
    It takes a lot of guts and courage to stand up for a cause and it can be very challenging when you get knock back after knock back. Olly is guiding you in spirit.
    Change can only come about when people band together and the ‘ripple effect’ keeps spreading wider into our communities.
    If they don’t change, people will be well informed. Your voices will be heard because you are informing people before they get their hands on that script.
    All my love and blessings to you all, Carla

    • Carla, I feel that your comment regarding the original intentional use of RoAccutane and its use, today, for acne is so very true. I also feel it’s true of SSRIs – surely intended for major depression but now handed out for the slightest hint of unhappiness. We all know why the companies do this, of course, it widens the market for their products and increases their profits no end. All of this without any further work on their part, no extra research to pay for – they’re laughing all the way to the bank……….and we are so gullible, we swallow every word that they utter. Haven’t NICE or the MHRA pointed out that SSRIs should only be used to treat major depression? – yet they seem to be shocked by the idea that these are still handed out for lesser ailments. Why can we not have a body, without anyone within it being in pharma’s grip, which could clamp down on these wrongdoings? Surely, in the long run, it would cost the country less to set up and run such a group than it does to compensate individuals for the injuries caused by the drugs? ( By compensate, I mean provide welfare benefits etc. – not compensation).
      I would really like to think that things are on the move as regards an awakening and a willingness to ‘stand up and be counted’ – following in David, Heather and the rest of their group’s footsteps – by ALL who have been injured in this way. To this end, we need to encourage the ones who have been lucky enough to recover and their families to join the ‘walking wounded’ and their families to support and sustain the struggle already being so bravely fought by the families who have lost loved ones – we must move together and make our voices stronger.
      Twelve months ago, had we been told that Brexit would have happened here in the UK or Donald Trump would become US president – we would have laughed it off as impossible. The reality is that the ‘ordinary man in the street’ has suddenly woken up and felt the pull of ‘group power’. Let’s make 2017 the year when the ‘group’ takes its ‘power’ to the people and awakens them to the grip of pharma – and ask for their support to help us to work towards a loosening of that grip, for the sake of future generations.

  4. Dear Mary,
    I agree with you wholeheartedly.
    People power is invariably, one way of creating CHANGE.
    The average person does have the power.
    Tapping into our unlimited resources and switching gears, is going to achieve ‘optimum’ results. It is al about changing our mindsets.
    Just look at what Erin Brockovick achieved! ; )
    Give me a podium, megaphone and a crowd of people and there will be ‘no one stopping’ me.
    We have these great ideas that could revolutionise STAGNANT thinking.
    Love Carla

    http://www.bing.com/search?q=if+today+was+your+last+day&src=IE-SearchBox&FORM=IENTSR&pc=EUPP_

  5. Some very interesting comments here, thanks to all of you. I do feel we need to come in from left field and try to offer solutions to the problems these drugs we’ve all listed, so that we make them redundant and we progress forward. Heaven knows, thousands of us, along with enlightened medical people, have been confronting Big Pharma head on endlessly and year after year, but their massive financial might scares governments and makes them appear unassailable. But if we find solutions to the problems the weary medics prescribe these drugs for, they will fade away like the dinosaurs they are.

    We need to move some different pieces on the chess board. Once we have shone light on new safer and more effective treatments, got them out into mainstream use, then we can turn back in force onto exacting some kind of retribution for all the Big Pharma criminal cover ups and torture of sufferers from their poisons, that has gone on. Our problem is, how to get the unbiased research going, using the best minds we have to make a real difference to the world.

    The Candle Vigil on 2nd November 2016 was a very good start. We harnessed our collective power of thought. That power can move mountains. Skeptics may not agree, but it has been shown to work in many spheres, time and time again. It is all that we have, but in a sense, it is the best thing of all. Let’s light more candles at Christmas and keep the energy flowing. We are unstoppable now, we are on our way. For the sake of our children’s futures, we have to stop this evil torture, and revert to basic common humanity and honour. And we will.

  6. Dear Heather,
    I agree with you whole heartedly.
    Lighting a candle, is a symbol of hope for all.
    Positive energy creates shifts in consciousness.
    Honouring humanity, is what this life is all about.

    I would like to take this opportunity to wish everyone a Merry Christmas and a Prosperous 2017 filled with lots of love, good health and happiness.
    When we stand united, all things are possible.
    Love Carla

    Great acts are made up of small deeds ~ Lao Tzu

  7. The Real “Mental Illness” Epidemic: Withdrawal from Antidepressants

    https://www.madinamerica.com/2016/12/real-mental-illness-epidemic-withdrawal-from-antidepressants/

    Drug companies prey on…children..

    http://www.baltimoresun.com/news/opinion/oped/bs-ed-youth-overmedication-20161225-story.html

    Patrick D Hahn

    No doubt this essay will elicit the obligatory incantations against “stigmatizing” the mentally ill. But there is a world of difference between stigmatizing the confused and vulnerable, and stigmatizing an industry that preys on the confused and vulnerable.

    • Another article of interest to you Annie, and many others is ‘Once Upon a Time in Withdrawal’ by Jarett Burke on Mad in America. I particularly like the final sentence or two – so very true!

  8. Yes; I thought it very powerful and , me too; true…

    “I had to be in bed with pillows over my head to block out all light and sound. I lay in bed wanting to die, daily.”

    https://www.madinamerica.com/2016/12/once-upon-time-withdrawal/

    Mary Newton December 31, 2016 at 12:33 am

    Jarett wrote:

    “Psychiatry can be a monstrous system where trusting people are chewed up and spit out.”

    Jarett,

    Kudos and brownie points to you for recognizing the worst and most neglected evil of the whole psychiatric system: the abuse of vulnerable people’s trust by powerful and well educated professionals. It compares unfavorably to priests’ sexual abuse of children. Children can grow up and escape their tormentors. Victims of psychiatry too often remain stunted and dependent until their too-early deaths, crippled by their faith in the god-like suits and heels who are paid so handsomely to stigmatize and drug them for life.
    So keep up the good work toward the day when we have a Pope Francis of Psychiatry who recognizes what’s going on and acts accordingly. How about going back to school and applying for the job yourself?

    Best regards,
    Mary Newton

    Pope Francis…..a Winning Smile, and two complimentary comments from the Mary’s..

  9. Mugs……..mug heaven..

    http://mpegmedia.abc.net.au/rn/podcast/2011/10/bbg_20111016.mp3

    with Dee Mangin and Jon Jureidini

    Quote:

    “sleazy”…

    Turning sorrow into sickness: An interview with Jon Jureidini

    http://www.psychotherapy.com.au/fileadmin/site_files/pdfs/Jon_Jureidini_Interview.pdf

    While not always attracting ‘approval’ from others in the debate, Jureidini has become a quiet voice of critical appraisal and common sense. In this interview, he talks about the impact of the increasing medicalisation of misery in our society.

    Sounds familiar…?

    BIG thing, small package…

    http://1boringoldman.com/index.php/2017/01/02/big-thing-small-package/

  10. Dear Annie,

    How can people be fooled by this nonsense?
    Marketing hype – destroy heathy people all in the name of science!
    Some people are just so gullible :’ ( just like I was! (past tense)

  11. Erin Rowlands, a 15 year old from Bangor, North Wales, has had her life wrecked by RoAccutane-isotretinoin. A ‘rare’ side effect nearly killed her, she lost all her hair and is now diabetic. Like Olly, she had been targeted by bullies at her school because of her skin. Her dosage of the drug was increased from 30mg to 70mg a day in 5 months. Parts of her pancreas started to die after inflammation stopped the blood flow. She is now diabetic and reliant on enzyme pills after 4 operations to save her life. The stress of all of this caused her hair to fall out and she has been advised that she may never now have children.

    She was in hospital for nearly 6 months and has lost 92% of her pancreas. Do followers of this Blog remember that RoAccutane was originally developed as a chemotherapy drug to treat brain tumours and pancreatic cancer? Interesting.

    Two days after her dosage was upped to 70mg she was sent home from school with severe abdominal pain. She spent 3 weeks in hospital with suspected pancreatitis (inflammation of the organ), which then developed into necrotising
    pancreatitis. She was sent to the Royal Liverpool University Hospital where she became the youngest person to have surgery for this condition.

    Ironically the RoAccutane did nothing to stop her acne. She is reported in the Daily Mail online (23Nov2015) as saying ‘it makes me so angry to think that all I’m going through is for nothing. I will never be cured. This is going to affect me for the rest of my life’. She is now diabetic because she can no longer produce insulin and needs a daily course of tablets, injections and anti-sickness drugs. She has been warned that she may never have children.

    She actually found a cream, costing £11, advertised in a magazine, that has now worked wonders on her acne.

    Elin’s family have apparently approached Swiss drugs firm ROCHE which makes RoAccutane, to list pancreatitis as a potential side effect. The Company says it recommends that the drug is prescribed carefully following advice in patient leaflets…. A spokesman said regulators agreed that its ‘clinical benefits outweigh the risks’.

    Notes written by hospital consultants linked RoAccutane to Erin’s health problems and asked for the medication to be stopped immediately. The Betsi Cadwaladr University Health Board which runs health services across North and Central Wales offered to meet with Miss Rowland’s family and discuss the case. That would have been in 2016 if it happened. It would be interesting to learn what came of it.

    So many people do not realise that pancreas and colon damage can occur due to this drug. They do not make the link, and so their symptoms are not reported as connected to the drug. There have been millions of dollars paid out in the USA for colon damage. After Olly died, in discussion with my cousin we learnt that her son had suffered stomach problems whilst on it, and another son, tipped for excellent A level results, underperformed because of its effects. They didn’t make the connection until they found out what had happened to Olly.

    Just trawling Google, there are endless cases of dire effects posted by desperate people about their ruined lives having taken this drug. Annie would have a field day if she researched them and put links on here. So many lives ruined. And still the horror and the risk goes on. And it would seem that unless we find an alernative and safe acne treatment, dermatologists will just smile wryly and say, ‘well, what else can we do?’ Quite a bit, actually, if they really spent some time and thought on it and came at it from a different mindset.

    • Erin’s story is certainly a very sad one which clearly shows the folly of using these strong medications for all the wrong reasons. There will always be the ‘doubters’ who will say that we can’t prove that the medication caused the real havoc which has devastated her life. That’s as may be but there are far too many similar stories of adverse reactions for the ‘coincidence’ tale to hold water any longer surely. There seem to be two ‘stings in the tail’ here in my view – one being the TRUE USE of this medication and the part of her body which was attacked by it; the other being the fact that a simple, fairly cheap cream worked so much better for her. Poor girl – if only hindsight could be accessed and reversed with a magic wand!
      Another young lady, from the same area of north wales, has recently started a mental health blog. This has no connection to Ro-Accutane but to antidepressants and antipsychotics. She suffers quite severely from the ‘lows’ of depression – but is doing remarkably well in dealing with it. She has a very different way of approaching her ‘low’ spells and is sharing many of her experiences in a friendly easy-reading manner.
      I know her from Twitter – as a Welsh speaker, but here she is using English in the hope of sharing her thoughts with a wider audience. Since many of us here feel, quite desperately, that we have to get our concerns out into the wider community and to a younger generation – I see her as a person who will do exactly that. She has over 2,000 followers on Twitter and shares her ‘mental ill-health journey’ there too – mainly in Welsh. I am sharing these details here, with her permission, in the hope that her stories will help us to move forwards and that our interest will help her to gain confidence and self-esteem in her ability to help others through her writing.
      Her name is Malan Wilkinson, found on Twitter @malanwilkinson and her blog is called ‘My Blue Blog’. Easiest way to access the blog seems to be from her Twitter account at the moment. It’s shown there in English so no Welsh lessons needed! I hope you find her writing as inspirational as I do.

      • Mary, Malan’s work is interesting and as you say, likely to become a very useful resource, particularly for young people like herself. She has many listed creative arts talents, and writes in a poetic and refreshing way. Thank you for alerting us to her blog, which is accessed via Google

        • Thank you for looking up Malan’s blog Heather. My comment was sent on one of the first days of her blog appearing which was before it could be accessed through a search engine. As you rightly say, it is now easily accessible via Google.
          I agree with you that she is multi-talented – the sad fact is that Malan herself has difficulty accepting that. It is for those two reasons that I mentioned her here – that she, undoubtedly, will do her best to promote mental wellbeing in any way possible and that, maybe, her confidence and self-esteem will be strengthened by the knowledge that others find her blog rewarding.

  12. It honestly doesn’t take a Field Day to find this stuff and I really hope that from the mounds of stuff on the IT, these few hit the spot.

    Accutane (isotretinoin)
    Everything you need to know about Accutane

    https://www.acne.org/accutane.html

    My happy son killed himself after taking the ‘wonder cure’ for acne: Warning from father of talented musician who was prescribed Roaccutane before committing suicide
    Musician Jesse Jones, 24, said he ‘hated’ the acne drug in last email sent to parents
    His body was found at the bottom of a cliff in Swanage, Dorset
    Parents Derek and Patsy, who feature in new documentary, say they will ‘everything they can to get the drug banned’
    Say prescribing is ‘like Russian roulette’
    Roaccutane manufacturer Roche deny ‘causal link’ between drug and depression or suicide
    Company say nine suicides reported in one year of 500,000 people known to be taking Roaccutane

    http://www.dailymail.co.uk/news/article-2234470/Roaccutane-effects-Warning-father-Jesse-Jones-talented-musician-commited-suicide.html

    Hollywood’s High Profile Accutane Lawsuit

    http://www.accutanelaw.org/

    Lawyers and Settlements.com

    https://www.lawyersandsettlements.com/lawsuit/accutane.html

    • It’s interesting that Annie you highlight, amongst all the hundreds and thousands of others, the example of the terrible loss of talented musician and student Jesse Jones, who died following what RoAccutane-isotretinoin did to him. Jesse’s brave parents made the wonderful film, ‘Dying for a Clear Skin’ shown first on BBC 3 in December 2012, too late sadly to save Olly, who would have been helped we feel sure to at last truly understand what effect the acne drug had really had on him, (contrary to the BS that doctors had blinded him with for years, by distracting him with talk of body dysmorphia because of his (by 2011) finally non existant acne, following Dr Tony Chu’s excellent Blue Light and laser treatment.

      Even though it was screened too late to save Olly, it was such a relief to discover that what we had suspected, right from the start of his ‘mental’ problems in 2001. We were just so fortunate that Jesse’s father was a Producer and made that film. (Rather like, interestingly Katinka Blackford Newman, also working in that media industry, was able to write ‘The Pill that Steals Lives’ and draw our attention to AKATHISIA, which has proved a magnificent key to our understanding of why people die by prescripticide).

      Jesse’s parents were able to collaborate on that film with the Medland family, whose very much loved son Jon was just completing his Finals in Medicine and had just a small amount of acne. He was prescribed the drug and within about 3 weeks he was dead. He had begun to experience the oft reported ‘low mood’ which must have suddenly become almost psychotic in intensity, just for a few moments. That, of course, is all it takes, just a few moments when the brain isn’t working right, and death comes so fast, for no reason at all. Like Jesse, Olly and all the others in our little group of 8, Jon had everything to live for. Their deaths made no sense at all.

      When you add an SSRI to combat the ‘low mood’, the results are equally dire, if not worse, because then AKATHISIA kicks in, more drugs are given, and the poor acne sufferer becomes branded for life as being mentally ill. Of course they are not, they are suffering organic brain disease, but no one seems to want to acknowledge this. Except Dr Doug Bremner, whose scans show it, but whom the MHRA discounts as not being worth including in their Government commissioned Report in November 2014. Bremner showed that in many cases, over 20% of the frontal lobes were not functioning. They are an area of the brain we use for our reasoning skills.

      I have just watched Leonnie Fennell’s brave, comprehensive but heartbreaking YouTube talk, about what an SSRI did to her dear son Shane, who was also dead within 3 weeks of taking it, and who had been driven to behave in a way totally out of character of this kind, funny, delightful brother. One would think that what happened to him, and to Jon Medland, although they were affected by two different medications, bearing in mind the short time between commencing taking them, and dying, one would think surely this is so obviously AKATHISIA that no one could fail to see it and ring alarm bells?

      But no. Beware of the Distracting Hand, says Leonnie. With RoAccutane, beware of being told that their acne drove them to their deaths. Beware of the subterfuge. Maybe if Donald Trump really does take on Big Pharma, there is a silver lining in view.

  13. There must be some way of making Pharmaceutical companies accountable for so much harm their products induce.
    I believe that any patient who was prescribed a medicine which induced dangerous side effects that the pharmaceutical company was aware of and failed to disclosed, should be sued.
    I also believe that patients who believe they ingested some defective medicine and were deceived by false advertising and dodgy manipulative business practices should also be sued.
    This is the only way we can make the dishonest pay for all the harm they have done!

  14. More on the theme of ‘what causes acne?’ And how it can be effectively treated without resorting to RoAccutane- isotretinoin.

    I was Googling all the references to RoAccutane I could find, trying to group together all the many posted side effects that people who had them, were suffering. Having found a lady who has a YouTube video about her permanent dry eyes and the problems they have brought (a horrendous story by the way), I stumbled on a YouTube video by ‘Organic Olivia’ who at length describes the three key elements to the causes she has discovered, and offers ways to eliminate acne
    .
    A lot of her ideas are based on common sense, clearing the gut, using the amino acid L-lysine, and she explains the role of hormones, facial cleansing and stress reduction. It’s quite long, very comprehensive, but well worth investing the time to listen. I thought it impressive and very helpful. So for anyone ( or even any open-minded brave dermatologist) not wanting to resort to using RoAccutane-isotretinoin, who has severe cystic acne (or indeed, any kind of acne), it gives the results of her fascinating research. I only wish our son had had information like this when he was 21. She also blogs on her website http://www.organicolivia about her long struggles with poor health until she discovered how the gut works and how it is key to good health when properly understood and treated with care and respect. I’d suggest that her video on YouTube could be a wonderful resource.

  15. Mental health reforms to focus on young people, says PM
    1 hour ago
    UK Politics

    http://www.bbc.co.uk/news/uk-politics-38548567

    We have Martha in the US, spelling it out..

    Pleasing Wall Street but Not Patients and Taxpayers: Pharma’s Plan for 2017?
    By Martha Rosenberg |
    January 7, 2017 AT 3:04 PM

    http://www.theepochtimes.com/n3/2207523-pleasing-wall-street-but-not-patients-and-taxpayers-pharmas-plan-for-2017/

    and then we have Charlotte in Bournemouth, doing some of the same..

    Should we be turning to antidepressants?

    http://buzz.bournemouth.ac.uk/2017/01/should-we-be-turning-to-antidepressants/

    and then we have…

    Professor Sir Simon Wessely, president of the Royal College of Psychiatrists, welcomed Mrs May’s “new and bold vision”, but added: “We have a long way to go before mental health services are on an equal footing with those for physical disorders.”

    You don’t think this is because it isn’t, as most doctors seem to make it all up as they go along and seem to develop a tendency to think off the hoof..

    There were no shortage of ‘experts’ when all six drugs were aimed at me through a pea-shooter…

  16. In search of Incredible..

    “Whatever has happened has happened”

    A rare glimpse in to the minds…of a ‘collection’ of psychiatrists..

    King’s Research Portal

    12 Sep 2013

    DSM-5: a collection of psychiatrist views on the changes, controversies, and future directions

    Charles B Nemeroff1,

    Daniel Weinberger2, Michael Rutter3, Harriet L MacMillan4, Richard A Bryant5,

    Simon Wessely6,

    Dan J Stein7, Carmine M Pariante8, Florian Seemüller9, Michael Berk10,11, Gin S Malhi12,13, Martin Preisig14, Martin Brüne15 and Paul Lysaker16,17

    https://kclpure.kcl.ac.uk/portal/files/12223031/Forum_on_DSM_5_BMC_Medicine.pdf

    and ‘declared’ competing interests…

    Competing interests

    CBN has received grants or research support from the National Institutes of Health (NIH) and Agency for Healthcare Research and Quality (AHRQ); has provided consultation for Xhale, Takeda, SK Pharma, Shire, Roche, Lilly, Allergan, and Mitsubishi Tanabe Pharma Development America; is a stockholder of CeNeRx BioPharma, PharmaNeuroBoost, Revaax Pharma, and Xhale; and has received income or equity from AstraZeneca Pharmaceuticals, PharmaNeuroBoost, CeNeRx BioPharma, NovaDel Pharma, Reevax Pharma, American Psychiatric Publishing, and Xhale. Other financial interests include CeNeRx BioPharma and PharmaNeuroBoost. CBN also holds patents for methods and devices for transdermal delivery of lithium (US 6,375,990B1) and methods of assessing antidepressant drug therapy via transport inhibition of monoamine neurotransmitters by ex vivo assay (US 7,148,027B2). He is also on the scientific advisory boards of American Foundation for Suicide Prevention (AFSP), CeNeRx BioPharma (2012), National Alliance for Research on Schizophrenia and Depression (NARSAD), Xhale, PharmaNeuroBoost (2012), Anxiety Disorders Association of America (ADAA), Skyland Trail, and AstraZeneca Pharmaceuticals (2009); and is on the board of directors of AFSP, Mt. Cook Pharma (2010), NovaDel (2011), Skyland Trail, Gratitude America, and ADAA.

    http://www.forbes.com/sites/paulthacker/2011/09/13/how-an-ethically-challenged-researcher-found-a-home-at-the-university-of-miami/#ba96879517b2

    http://www.nytimes.com/2008/10/04/health/policy/04drug.html

    http://www.pogo.org/our-work/letters/2010/ph-iis-20101129.html

    Mr Witty said: “It’s appropriate that we have a limit on what we pay. In the past, whatever has happened has happened, but in the future there will be strict adherence to these caps, which will be clearer to everybody.”

    Pre Paywall –
    https://www.ft.com/content/7f6917aa-a067-11dd-80a0-000077b07658

    Financial Times

    October 23, 2008 3:00 am
    GSK to publish level of advisory fees for doctors
    By Andrew Jack

    GlaxoSmithKline is to make public the level of advisory fees it offers to doctors and medical academics, and will strictly cap the payments they can receive in the US to $150,000 (£88,000) a year each.
    Andrew Witty, chief executive of the UK-based pharmaceutical company, said he was introducing tougher new rules to impose a cap “without exception” on such payments and promised to publish the amounts.
    His commitment comes at a time of growing concern that the widespread practice of payments by pharmaceutical companies may help unfairly influence “key opinion leaders” in the medical community, in a way that biases their judgments and recommendations for particular treatments.
    GSK has recently been drawn into the debate in the US, after reports that Charles Nemeroff, chairman of the psychiatry department at Emory university in Atlanta, had received nearly $1m in fees from the company during 2000-06, most of which it is claimed he had not disclosed. He has recently stepped down from his post pending the outcome of an internal inquiry.
    In Europe, the Dutch Health Inspectorate is investigating concerns about payments from GSK to academics who sit on the Health Council, an advisory body that recommended the use of Cervarix, the company’s recently launched drug to protect against cervical cancer. GSK said it had received “no allegations of misconduct”.
    The cases have added support to a proposal from Senator Charles Grassley in the US to introduce “sunshine” legislation designed to require publication of fees paid to doctors, although the fate of his bill remains unclear.
    “It’s appropriate that we have a limit on what we pay,” said Mr Witty. “In the past, whatever has happened has happened, but in the future there will be strict adherence to these caps, which will be clearer to everybody.” The company added that the “timing and infrastructure” of publishing details of its payments had yet to be determined.
    The US National Institutes of Health, a large funder of academic research, as well as leading academic medical journals, have requirements for disclosure of conflicts of interests through both advisory fees to academics and broader support to their universities and institutions.
    However, such disclosures are difficult to police and public registers of payments would make it far easier to identify any discrepancies.
    The pharmaceutical industry has taken steps in recent years to limit accusations of influencing doctors, curbing lavish entertainment and luxury travel under the pretext of supporting their attendance at academic conferences. But critics continue to question payments to individual doctors as speakers and advisers to companies, as well as the drug industry’s heavy sponsorship of continuing professional medical education.

    Bully pulpit
    http://1boringoldman.com/index.php/2017/01/11/more-bully-pulpit/

  17. More Questions than Answers…

    For:

    https://www.baumhedlundlaw.com/prescription-drugs/paxil-injuries/

    https://www.baumhedlundlaw.com/pharma-news/paxil-news/

    Against:

    http://www.seroxatusergroup.org.uk/MHRA_investigation_GSKSeroxat%5B1%5D.pdf

    Comment left on the FT..

    uiuiuiui

    Jan 3, 2016

    Here’s an obvious point for readers and GSK investors alike. Glaxo’s share price has been in a secular decline since the SmithKlineBeecham merger in 2001. To assume that a CEO who has been in charge for 9 of those 14 years can wordsmith/market/spin/cherry pick facts (to analysts) and reverse ~$70 billion dollars of shareholder value destruction is at best a fallacy and at worst a fraud. It implies that the leadership ‘cult of the CEO’ is more important than the working culture of the underlying company. In reality what we are witnessing with GSK is simply a crisis of competence, not of confidence. The right people need to be in the right job to have a chance to change a decades long secular decline. Good luck with your powerpoint slides!

    Data Based Medicine..
    https://davidhealy.org/study-329/

    Adam Jacobs @statsguyuk
    Oh good grief. As if the “50% unreported” statistic weren’t mendacious enough… #zombiestatistics #AllTrials
    9h

  18. In the case of RoAccutane-isotretinoin, it was taken off the market in the US reportedly for ‘commercial reasons ‘ but many of us think it was because Roche had had to pay out billions in compensation for people whose colons had had to be removed, due to the damage, irrefutable, from the drug. Roche usually seems to settle out of court finally, having dragged out the legal trials for as long as possible, to wear down their opponents. In UK it would be interesting to know how many colostomies have been necessary because of this drug.

    David Chow, who died a year or so ago, had bravely struggled with chelitis of his lips, and subsequent damage to his jaw, all caused by the drug. He suffered terrible pain, yet despite this, he and his anaesthetist father did all they could to raise awareness of the horrors of RoAccutane-isotretinoin. David’s lips were so irreparably damaged that he could only eat and drink for many years via a straw. The bravery of this man is incredible. Despite the drug having taken away his chance of a relaxed social life, he produced an amazing collection of wonderful photography and lived for 17 years until the pain, like Olly’s, became too much.

    The Internet is FULL (like Annie said earlier) of accounts of ruined lives, caused by this drug. Then, to be fair, we read of others for whom it has taken away their disfiguring acne. But many say it has returned as soon as they stop taking it. There is even an account written about the neurological and physical damage suffered by a girl whose mother apparently took it all through her pregnancy. This girl states that her life is almost unbearable. Normally these days no pregnancy would be allowed to proceed if the mother was on the drug. But with it’s availability on the Internet, one wonders how many youngsters have taken it without the required safety monitoring by their doctors? We know from the BBC Investigation about its availability online, that the Turkish importer, buying it legitimately from Roche, said he’d been selling it online for 10 years (!) and apparently Roche hadn’t told him how important the safety measures were, it being such a dangerous drug. A young person is most unlikely to admit to their GP that they have bought it secretly. They will just swallow it down, with no liver checks or blood tests to monitor their own health safety. And if they get pregnant, then what do they do? Are we therefore going to see a lot more damaged babies in years to come? Remember, one of its original inventors said he feared it would become the new Thalidomide.

  19. Where are the human rights lawyers to support all of us?
    We need to be protected by people who discriminate, defame, shame and compromise us.
    The drugs have ruined our good health and innocent people have unjustly died.
    We need support ~ not eternal condemnation!
    Humanity needs to be protected.
    We need to learn from past mistakes.
    Anything that is unprofessional or inhumane, should be investigated and the public need to be made aware of any unethical business ~ no questions asked!
    Carla Bataljin

  20. One other thing which MUST be said. Cystic acne, (or indeed any disfiguring acne) is surely one of the worst things that can be inflicted on a young person. I well remember the utter hell it was for me. All through my teen years, I wanted to hide away and not be noticed at school. Every time I walked into my classroom in the mornings, knowing I couldn’t hide the latest crop, I was overcome with a ridiculous kind of shame. One girl used to say to me ‘you are so ugly, why don’t you just die?’ But I wasn’t suicidal, I wanted a solution.

    I lived in London then. Aged 15 I used to catch the Underground to Knightsbridge, quite a long way into town from my home, and secretly used the sun tanning cubicles at a place where you put money in a door slot and set a time on the machine, put on goggles, and toasted yourself. I did this for quite some time, till my horrified mother somehow found out. I guess, looking a bit like a lobster must have given me away. ‘Don’t you realise, you could get skin cancer when you are older? she pleaded. But I couldn’t have given a hoot about when I was older and what the ultraviolet light could have caused. My life was frustratingly compromised NOW because of the wretched acne. Antibiotics like Tetracyline just gave me thrush and did no good anyway. We compromised and bought a little sunlamps to use carefully at home. It helped a bit.

    What I’m trying to say is that, aged 15, if there had been the chance of getting my hands on RoAccutane-isotretinoin, even if secretly on the Internet, (had it existed then) I would have begged borrowed or even stolen the money to send for it. I wouldn’t have cared AT ALL about possible side effects. No one who has not suffered the plague of bad acne can possibly imagine how awful it makes you feel. This is why Roche are in one sense right when they say people can feel suicidal about their skin. But it’s exactly why we MUST find a safe and effective treatment for cystic acne, and make their dangerous drug obsolete urgently, because it is just too cruel to mess up the minds (and bodies) of those who are already suffering hell, by expecting them to play Russian roulette by taking this drug. And then if the poor soul gets ‘low mood’, and is given an SSRI, becomes AKATHISIC (unrecognised of course), then chances are, all their life’s dreams, college, happy social life, carefree creativity, may be gone. We must unite to change this. But, like I wrote earlier, with Big Pharma Roche in total control, and dermatologists desperate, how on earth do we do it?

  21. The C.hronicles of N.arnia..

    Charles Nemeroff MD

    “Depression and other psychiatric disorders are brain diseases..

    https://www.youtube.com/watch?v=iNERCNkFxbQ

    Conflicting Interests in Toronto
    anatomy of a controversy at the interface of academia and industry
    David Healy

    http://www.healyprozac.com/AcademicFreedom/Conflicting-Interests-in-Toronto.pdf

    Pharma politics..

    http://www.pharmapolitics.com/cbcnational.html

    http://ahrp.org/bitter-pill-for-david-healy-academia-under-pharma-influence/

    Ghostbusting in Paxil Birth Defect Litigation

    http://www.healthsentinel.com/joomla/index.php?option=com_content&view=article&id=2735:ghostbusting-in-paxil-birth-defect-litigation&catid=5:original&Itemid=24

    The next person the jury heard about was Charles Nemeroff. He was also an author on the atypical study. Nemeroff was the Chief of Psychiatry at Emory, until he lost the position last year, Healy told the jury. “He’s possibly best known or was the best known psychiatrist in the United States.”
    “He influenced an awful lot of heads of departments, professors of psychiatry, general people within the field of academic mental health, and through them and an awful lot of prescribing doctors here in the U.S. And, indeed, perhaps worldwide,” Healy testified.
    A link to “Articles” on the Emory website in mid-2009, brought up roughly 90 studies and papers that include the co-author Nemeroff.
    Healy said he believed Nemeroff was one of the founding members of the Paxil advisory board and he participated in continuing medical education seminars with talks on Paxil.
    Nemeroff would have been “the key person in producing the kinds of talks with slides that would have been held for large audiences of doctors, and then those slides and talks would have been distributed out to different doctors in the field who hadn’t been at the major meetings as he gave his talk,” Healy told the jury.

    • In 2007 Nemeroff was the second author on a paper about dopamine and depression. One line stands out.

      “There is now an emerging consensus that the majority of depressed patients treated with selective serotonin reuptake inhibitors (SSRIs) and selective serotonin/norepinephrine re- uptake inhibitors (SNRIs) do not attain remission.”

      Now you tell us.

      And at the end:
      “It is now clear that treatment with [SSRIs and SNRIs], although clearly superior to placebo treatment, frequently fail to render patients symptom free; ie, the majority do not achieve remission.”

      In both cases, he’s saying the majority still suffer from depression while taking antidepressants.

      He did a lot of damage before coming to that conclusion. (For both claims, the APA’s guidelines for treating patients with depression, ca. 2000, is cited as the source.)

  22. Nice tie….

    https://www.madinamerica.com/2017/01/mia-year-2017/

    https://www.madinamerica.com/psychiatry-past-present/

    TRM123 January 13, 2017 at 12:15 pm
    Thank you Bob, and thanks to all your colleagues at MIA who have had such a successful 2016.
    Knowledge, Understanding, and Hope are found here.
    These are the critical success factors for the continued survival of those who themselves, or whose loved ones, have suffered so terribly from the arrogance, dogma and inflexibility of the casual and careless prescribers, who impose psychotropic drugging by deception, coercion and enforcement.
    Sir William Osler observed: –
    “The greater the ignorance, the greater the dogmatism”.
    These words appear bespoke for those detractors who fear and contest your great humane and compassionate endeavour.
    Retired Consultant Physician. U.K.

  23. In Annie’s comment on Jan 11th she lists, amongst many others, Charlie Nemeroff. I have previously mentioned that the main brave voice speaking out with his results of research into the harms of Accutane, was Dr Doug Bremner in the USA. He worked at Emory Uni alongside Charlie Nemeroff, well, in a position under him I assume. Dr Bremner, a psychiatrist, had been employed to promote Accutane, but some parents approached him after the bizarre behaviour of their son whilst on it and he began to collate similar cases (including suicides) and, like the good doctor he was and is, suggested that all was not well with this drug. A parent paid for him to do some further research and his results were mind blowing. But Charlie Nemeroff, along with others, did everything they could to undermine his efforts, threatening to ruin his career. It was only because the scandal broke, about Nemeroff’s undisclosed payments from drug companies, that Dr Bremner was saved. He has written a wonderful book called ‘The Goose that Laid the Golden Egg – Accutane, the truth that had to be told’ telling the story of his research and how he was targeted and worn down by the attempts of Big Pharma (Roche) working with Nemeroff, to totally discredit him. The book is interesting as not only does it explain the scientific research, but also describes the author’s own psychological personal experiences along the way, in an almost spiritual sense. On first reading it I wondered if he’d put this element in as a kind of smokescreen to water down his crusade about Accutane and deflect the ire of his critics. He has written other excellent books, such as ‘Before you Take that Pill’ dealing with side effects from all kinds of medications.

    When our group of parents met Earl Howe at Portcullis House in February 2014, the MHRA representative was present, along with Sir Nick Harvey (now ex) Lib MP for Barnstaple, Ed Vaisey (Con) MP, Gordon Henderson (Con) MP, and Norman Lamb (Lib) MP, at that time in Cameron’s Cabinet. When Earl Howe asked the MHRA to investigate this drug YET AGAIN, we all asked for Dr Bremner’s research to be included, especially his scans which show that 21% of the frontal lobes in the brains of those taking Accutane/RoAccutane/ isotretinoin can be destroyed by it. The woman from the MHRA brushed this request aside, just saying ‘we do not rate his research’ or words to that effect. So it was not included in the Report, but the opinions of various pro-RoAccutane dermatologists and others, were. It is thus easy to see why, however hard the damaged users try to warn others, and get better treatment for acne, they are crying in the wilderness.

    Maybe only by highlighting the unhealthy alliance between the MHRA and Roche, just like the unhealthy alliance of Nemeroff and Big Pharma, will we begin to wake the world up. And let’s not forget the role Nemeroff played in Dr David Healy’s loss of his appointment to a prodigious position in Canada. Thank heavens for the Internet, so that at least we can find out all sides of a story, and not have to rely on being spoon fed by a biased Murdoch owned Media.

  24. Dear RXISK community,

    I want to share something with all the RXISK community.
    Today, I decided to step outside my comfort zone and seek some support.
    I feel empowered.
    I feel positive.
    I know that we will all have our voices heard.

    I wrote a brief email message to Jeffery Robertson’s firm, who is a human rights lawyer in the UK. I will not give up without a fight.
    I know he will lobby for all of us. It is inevitable.
    This is what I emailed to him.

    Sixteen years ago, my husband and I ingested one tablet out of valium which had very devastating effects.
    I have not been given an opportunity to speak up because the processes and systems have allowed me to fall through the cracks.
    I believe the batch which was prescribed to me was a counterfeit or manufactured to induce problems.
    Took me a long time to make a connection.
    I also believe that the Government has not taken any responsibility for what has happened.
    I have served my prison sentence ~psychological vilification & character defamation (labelling me as mentally unstable-which are not true). How does one prove their innocence in this complete horror story?
    The endless labels which have been put on me are preventing me from speaking the TRUTH.
    I am dying inside knowing what I know today however, if someone believed in my story, it would somehow make my life worthwhile knowing that I have done the best I can to prevent tragedies like mine occurring to someone else.
    The drug manufacturers have known that benzos’ and other antidepressants induce dangerous side effects however, they have been very negligent in failing to make this known to consumers.
    Please do not ignore me because I feel like I have paid my prison sentence and need to get my story out there about how I have been wrongly accused.
    How can I let go of something if it had a major impact on my health and whole family?
    I am terrified of speaking up because there are powers out there that will not allow me to speak up. I know that my story has to be told so that I can assist with making legislative changes that will benefit all. Seem to be getting no where with my story because everyone is questioning the legitimacy of it.
    Would anyone shy away knowing that a drug has severely harmed one. I have received the SILENCE TREATMENT from everyone, when ever I try to bring my case up. This experience seems so surreal and each day I say that if I let it go, I will go to my grave with grave regrets. I am at complete loss with how my matter has been handled.
    I will not give up without a fight.
    I would appreciate it immensely if someone like Jeffery Robertson would lobby for all us voiceless ‘injured ones.’
    In South Australia no one has had the audacity to support me.

    With many thanks
    Carla Bataljin

    PS I know that the universe is going to support all of us.
    We deserve the best outcome for humanity.

    • Good on you Carla – I’m with you all the way, as, I’m sure, are the rest of us who read or comment here.
      It’s amazing how things happen. At 7.15 this morning, I listened to a Welsh language Pause for Thought, given by a young lady whose new blog I recently mentioned on RxISK. In the main, she spoke of ‘fear’ – thinking about the possible fear felt across the waters as America awaits its new President. She finished by saying that ‘fear’ can hold us back; that the way forward is to have ‘faith’ in its broadest sense – and that, by faith, we can explore the possibility of each little one of us being able to make a difference……Now, a few hours later, after considering her words off and on since I heard them, I switched on my laptop – and here you are Carla, the one little voice, standing up with ‘faith’ for what is right. As fellows in the ‘faith’ you can bank on our support at all times. I look forward to hearing more about your ‘marching on’. Good luck.

  25. Update

    https://petition.parliament.uk/petitions/163527

    Update Psychiatric Diagnosis Procedures so they are accountable & evidence-based
    Psychiatry is under criticism for its subjectivity and unaccountability. Brief crises are defined as lifelong conditions. There is no recognition of this ambiguity. Complaints are seen as symptoms. Patients are misunderstood or slandered. The pessimism of working in a Hospital causes Confirmation Bias.
    ▼More details
    Psychiatry in its present form is based on a one-to-one interview that is then written up from the memory of the person who conducted the interview. This leaves a lot of scope for misrepresentation,and hard evidence such as videotape is not used. Nor is there group inter-rater reliability,but instead the creation of a “United Front” of Professional Vanity to prevent criticism.
    “On being sane in insane places” Rosenhan;
    “The Psychopath Test” Jon Ronson;
    “The Stanford Prison Experiment” Zimbardo

    Update

    James Moore continues, with an interview with Charlotte Very’ard

    https://www.change.org/p/secretary-of-state-for-health-jeremy-hunt-make-pharmaceutical-firms-help-users-who-want-to-stop-taking-anxiety-depression-drugs/u/19058537?utm_medium=email&utm_source=notification&utm_campaign=petition_update

    http://buzz.bournemouth.ac.uk/2017/01/antidepressant-withdrawal/

    And so we swallowed Paroxetine at a time in the 90’s and 2000s when all this was going on and some of us were classified as ‘Subjectively Depressed’ which is an airy fairy opinion at best and a destiny of death at worst…

    The Petitions are mounting up..

    Update

    https://twitter.com/hashtag/ReformMHRA?src=hash

  26. Update

    https://www.change.org/p/house-of-commons-to-disband-the-medicines-and-healthcare-products-regulatory-agency-mhra-a-corrupt-government-body-charged-with-protecting-patients-from-avoidable-harm-in-the-national-health-service-and-in-public-health

    Dr June Raine, Director of
    Post-Licensing Division, MCA
    Market Towers, 1 Nine Elms Lane
    LONDON SW8 5NQ

    7 June 2000

    Dear Dr Raine,

    You may or may not have heard that yesterday in Cheyenne, Wyoming a Court found Glaxo SmithKline guilty on several accounts including the count that Paroxetine can cause suicidality, that it specifically did so and contributed to the wrongful death of Don and Rita Schell as well as Deborah and Alyssa Tobin and that the company had been responsible for a failure to test and a failure to warn. You may also be aware of a verdict in the Hawkins case in New South Wales some weeks ago where a Supreme Court Judge made it clear that in his opinion Mr David Hawkins would not have murdered his wife but for the influence of Sertraline.

    In the course of my work as an expert witness in Tobin versus SmithKline I got the chance to look at SmithKline’s healthy volunteer database in Harlow. Their characterisation of this for you was that: “There were no reports of suicidal thoughts in any of the volunteer studies. There were few reports of ’emotional lability’, however these reactions were not found to be related to suicidal thoughts or behaviour. Some volunteers reported anxiety, nervousness and agitation while taking paroxetine, however the most commonly reported adverse events were nausea, diarrhoea, drowsiness and insomnia”.

    What I found was that approximately 25% of the volunteers in the studies that I reviewed which were all of the healthy volunteer studies done prior to the filing of this drug for registration in the US and in the UK – 34 studies approximately in all. These yielded a 25% agitation, nervousness/akathisia rate. Some of the multiple does studies in healthy volunteers lasting 2-3 weeks yielded an up to 85% withdrawal rate in the volunteers.

    All of their healthy volunteer studies were supposed to have been made available to me but not all were. Of the ones that were missing there was trace correspondence left in once indicating that the investigator had never witnessed such a level of problems in a study with healthy volunteers. Another study was a single dose study which in a dose dependent fashion yielded a 75% rate of severe adverse events most of which involved the central nervous system. There were other disturbing indications from one of the other missing studies.

    Volunteers who had participated in the programme went on to suicidal acts. The relationship between their intake of paroxetine and later suicidal acts is a matter about which neither you nor SmithKline Beecham should be sanguine.

    These studies were for the most part done on company employees. None of the studies bar the missing ones were done by investigators with a background in psychiatry. The investigators were general physicians with a primary interest in gastrointestinal problems who could not have been expected to detect mental problems of this sort that have concerned me and I would have thought should concern you.

    My testimony in this case also bore witness to sealed studies and other unreported data. It commented on the Montgomery Baldwin Study which yielded a projected rate of 45 suicide attempts in a group of recurrent brief depressive disordered patients on paroxetine per annum versus 12 on placebo. The figures were not statistically significant in great part one has to suggest because the company had terminated the study early. This termination and subsequent non-publication I would imagine the jury will have found and others will find significant.

    Dr Hudson, currently of the MCA, was a witness for SmithKline in this case. He may well be able to give you further details on some of the issues involved. His testimony involved repeated reference to the fact that SmithKline Beecham cannot decide whether their drug had caused problems such as the wrongful death of Don and Rita Schell or Deborah and Alyssa Tobin or the wrongful deaths of many other people whose deaths have been reported to SmithKline even when these reports have been accompanied by the opinions of their treating physicians that the drug had indeed contributed to the problem. Dr Hudson’s testimony was that until controlled trials or other similar studies had proven in general that paroxetine could cause such problems that the company could not make decisions on any specific case.

    This appears to me a Black Hole defence. It is entirely conceivable that tens of thousands of suicides could disappear into this Black Hole without either SmithKline Beecham, Pfizer or Eli Lilly being called upon to make any judgements as to whether their drug was contributing to the problem. The lack of evidence from randomised controlled trials or epidemiological studies in this context is not evidence of a lack of a problem. It stems explicitly from failures of SmithKline Beecham, Pfizer or Lilly to do the requisite studies. Both David Wheadon and Christine Blumhardt from SmithKline as well as Roger Lane from Pfizer and Charles Beasley from Eli Lilly along with outside experts such as Daniel Casey and John Mann have testified under oath in the course of the last year that there have been no studies undertaken by any of these companies or others that have been designed to test whether the SSRIs could cause a problem. I believe that this will in due course be seen for the extraordinary state of affairs that it is.

    I think what will also be clear is that SmithKline Beecham recognised the presence of withdrawal syndromes in their volunteers from the early to mid 1980s. That withdrawal syndromes occurred at a much higher rate than occur on benzodiazepines. Nevertheless they applied for and have received from you and other regulators a licence to claim that their drug is effective in the prophylaxis of depression and these claims have been based on designs which almost certainly are designs better suited to show the presence of a withdrawal syndrome than designs suited to demonstrate prophylaxis in depressive disorders. A great number of people have in recent years been told that when they begin to feel ill on discontinuing treatment that this is the recrudescence of their mood disorder rather than a discontinuation syndrome from their drug. I would imagine that a great many such people and others on their behalf will feel extraordinarily let down and angry when faced with the evidence that I’ve been faced with.

    Yours sincerely

    David Healy MD FRCPsych
    Director, North Wales Department of Psychological Medicine

    http://fiddaman.blogspot.co.uk/2009/06/mhras-june-raine-honoured-with-cbe.html

  27. This has to be one of my favourite posts..

    https://davidhealy.org/42-or-thereabouts/

    The *comments* were…pure dead brilliant..

    When we moved to Argyll, in the 80s, a Lady pilot and her husband became great friends introduced to me by my partner, an airline pilot.

    C and C met at a Welsh primary school and she learned to fly and he engineered.

    They started up their own airline in their 20s and bought an aeroplane and did pleasure flights and then cargo traffic all over the world. Just the two of them.

    Fanatical about planes and boats their life was ups and downs and their ‘anecdotes’ staggeringly hilarious and mind boggling at the same time..

    The scrapes they got into and all this was documented in the most amazing film they made of their love affair as teens and subsequent life as flyers. He did this for his wife…as a memento. He had documented everything from the day they met until they got old..

    When I had my baby they were the ones who created so much fun for us with sailing at night and visits to air shows and the like.

    When I was placed in the Mental Hospital at the direction of the gp after cold turkey from Seroxat, they were the ones who travelled to visit me.

    I remember we sat huddled in a corridor with their concern for me.

    After the two years of my prescription drug abuse and so on, C had some sort of breakdown.

    Her gp sent her to the same mental hospital.

    I visited C and got permission to take her out for lunch.

    She was nosediving and crashing in to people’s lunch and was obviously on ‘medication’.

    When she left we all sort of carried on, but, our friendship was destroyed because I was so damaged from all those drugs and she was not quite the same either, and so we floundered around for a while but all the old enthusiasms had gone and it was difficult to pick up the reins from where we had left off.

    I feel terrible about it now, as friends like C and C don’t come around very often and I often wonder how it is possible to pick up all those friendships I lost because some Scottish Heathens decided that
    Seroxat and Suicide would stick to me like glue..

    Nobody knew what gps and consultants had done to me because they were never going to own up and neither were their superiors…the long and deliberate cover up affected every area of my life, not just one or two aspects, and it really is quite shamefully corrupt.

    “it was terrible what they did to you” remarked my art teacher.
    The one who had sat with me in my garden for weeks when all I did was stare in to space..

    All through my life I have had remarkable friendships with remarkable people.

    At least, this friendship stayed alive..it might be time to go back and collect the losses..

  28. Dr David Healy, who was prepared to testify in support of reduction of my sentence, has additionally concluded that:

    “This case is about as simple and straightforward as it gets, and bears all the hallmarks of a treatment induced problem…I believe there is a strong case to be made, but for the Prozac he took, Mr Danysh would not have killed his father (Emphasis added)

    http://www.thepillthatsteals.com/blog/

    From Patient to Prisoner
    By Kurt M. Danysh

    David Healy..essential viewing..

    http://www.kurtdanysh.com/about.htm

  29. Dear David,

    Without you, many voices would go ‘unheard’.
    Listening to one testimony after another testimony, is proof, that these meds are dangerous and that the ‘gatekeepers’ are being totally NEGLIGENT in matters pertaining to peoples SAFETY ~ We already know about this!
    All people need to be made aware of the TRUTH and until it is all disclosed, unnecessary MAIMING, SUICIDES & HOMICIDES, will continue to occur.

    Thank you David for taking a stand and trying to create an awareness, when no one else was believed.
    You are the voice who will shed LIGHT for the VOICELESS.
    Thank you, for believing in us and making drug companies accountable. The unnecessary harm these meds induces and the terrible thoughts that rage through peoples minds, whilst on these meds, is a constant reminder that can no longer be dismissed.

    Sending you many thoughts of gratitude,
    Carla

    http://www.kurtdanysh.com/about.htm

  30. “mouse-killing behaviour”

    http://www.thepillthatsteals.com/blog/

    Comments (2)

    Anne-Marie 20 hours ago

    The Zoloft litigation Manual that all Prosecutors have.
    https://healthwyze.org/archive/zoloft_defense_manual.pdf

    Anne-Marie 20 hours ago

    This story is really, really very shocking! I am really sorry Kurt this has happened to you and your family. There should be an urgent inquiry into this, this is so serious. This following bit really has enraged me, it proves to me that they know and always have done.
    Lilly has known since the 80’s that Prozac is capable of causing violent behavior, to include homicidality, in some patients. Nonetheless, since 1991, Lilly has conspired with prosecutors to convict criminal defendants who raise the so-called “Prozac Defense.” (1) These efforts include providing expert witnesses at trial (to combat claims that the drug caused the defendants’s violent offense(s) and even financing entire prosecutions. (2)
    Other antidepressant manufacturers have followed Lilly’s lead. Pfizer, the manufacturer of Zoloft, went as far as creating a “Zoloft Litigation Manual”, which it prepared “in anticipation of litigation to assist Pfizer’s lawyers, and lawyers in prosecutor’s offices with common interests, in responding to civil claim or criminal defense” claiming that Zoloft induced violent behavior. (3)

    https://healthwyze.org/archive/zoloft_defense_manual.pdf

    “In the first clinical trial of its kind, Dr David Healy, director of the North Wales Department of Psychological Medicine at the University of Wales, gave Prozac to a volunteer group of mentally healthy adults and found even their behaviour was affected. He said: ‘We can make healthy volunteers belligerent, fearful, suicidal, and even pose a risk to others.’

    Healy says between one in 20 and one in 10 people who take Prozac can be affected by akathisia, whereby they become mentally restless or manic and lose all inhibitions about their actions ‘People don’t care about the consequences as you’d normally expect. They’re not bothered about contemplating something they would usually be scared of,’ he said.”

    “described as ” Pfizer’s Zoloft Litigation Manual ” and is an exhibit from the Christopher Pittman double murder trial.

  31. Annie, you have highlighted a key part of the damage that Seroxat SSRIs and no doubt many other SSRIs and RoAccutane and Lariam (these last two made by ROCHE), do to relationships and our standing socially in the eyes of others, even in some cases, family. The fear that an implied diagnosis of ‘mental’ illness generates in those around the victim tends to drive a wedge in between relationships. Once you are ‘branded’, no one is ever really quite comfortable with you again. And, as Carla has also written, no one will put their hands up to the fact that the medicines caused the severe symptoms which have got you labelled as ‘mentally’ ill. The whole wicked scenario reminds me of the story of the Count of Monticristo who was thrown into jail for life, deteriorated, was hidden away and starved, but by a stroke of luck, found guidance and a means to escape and get retribution, naming, shaming and ruining those who did such a terrible thing to him by persevering with hope and righteous indignation at the injustice done to him, and never giving up. In a sense the RxISK Blog is one excellent way for sufferers to unite and reverse the stigma they’ve so wrongly been labelled with.

    By the way Annie, you mention airline pilots. It should be noted that if you have taken RoAccutane-isotretinoin you cannot become a pilot, because of night blindness which can be a side effect, as well as other sight problems. Similarly with Lariam, the anti malarial drug, whose effects are very like RoAccutane, and also made by ROCHE. In Australia, army personnel on Lariam are not supposed to be allowed to fly planes whilst they are on it.

    Should anyone, without our knowledge and informed consent, be allowed to mess with our neurology, and then, having rendered us vulnerable and defenceless, have the audacity to deny that they’ve done it, by branding us as ‘mentally’ ill? We call ourselves a civilised society. But surely, like Carla says, this is a crime against humanity and until the herd see and take steps to right it, it is only the injured or their bereaved loved ones who are left to fight for justice.

  32. On the Radio 4 BBC ‘Today’ programme this morning, a reference was made to the findings of a recent report on the benefits of CBT in psychosis. The consultant interviewed said it worked by using the brain’s plasticity to change the way it worked, and find a way to deal with difficulties.

    This is great, but only, I feel, if the brain is working as a person’s unadulterated mind, free of any use beforehand of psychotropic drugs. Olly did years of CBT. But his mind was already organically messed up/ changed by RoAccutane-isotretinoin and further by SSRIs and eventually anti-psychotics too. He got to a point when he could neither see, read, think clearly, or finally make reasoned judgements in relation to his own personal pain and whether death was his only way out. He could still manage his commercial work, which was automatic after so many years of doing it, and in one sense anchored him to life. But the CBT words on the page did not ‘hit the spot’. He was however shouted at by a psychiatrist who obviously felt that CBT should have counteracted the AKATHISIA he experienced when told to come off Venlafaxine cold turkey. Impossible. You have to have your normal mind in working order to get benefit from CBT, and it won’t be if prescribed drugs have already limited its processing and learning ability.

    Better surely to bring in Social Prescribing, good listening companionship, and yes, CBT if it helps, but don’t cloud it’s effectiveness in a cotton wool mush of SSRIs. According to ‘Anatomy of an Epidemic’, the brain on SSRIs is changed within 3 weeks. According to ‘The Pill that Steals Lives’, it need only take 3 days. Wake up and smell the coffee folks.

  33. Muddy Studies…

    http://www.thetimes.co.uk/edition/comment/muddy-studies-9dql0tf55

    Making one’s mind; up…

    “Psychiatry is at the heart of medicine…

    http://www.rcpsych.ac.uk/

    Professor Sir Simon Wessely, president of the Royal College of Psychiatrists, welcomed Mrs May’s “new and bold vision”, but added: “We have a long way to go before mental health services are on an equal footing with those for physical disorders.”

    Simon Wessely ‏@WesselyS 13m13 minutes ago

    Small kittens or large sabre toothed felines? My guest blog on the PM’s speech (no not Brexit) via @mhtodaymag https://www.mentalhealthtoday.co.uk/its-official-there-is-such-a-thing-as-society.aspx …

    https://www.mentalhealthtoday.co.uk/its-official-there-is-such-a-thing-as-society.aspx

    Is this useful, illuminating, brightly lit or anything else…?

    The ‘other half’..

    Clare Gerada ‏@clarercgp 3h3 hours ago

    Last few days to vote for @WesselyS replacement (if he ever can be replaced) as President
    @rcpsych – I know who i voted for!

    http://www.pinknews.co.uk/2013/11/27/worlds-most-senior-psychiatrist-comes-out-and-says-profession-should-apologise-to-gay-people/

    world’s most senior psychiatrist comes out and says profession should apologise to gay people……….how about apologising to the patients, first, Dr. Bhugra..

    The Top Jobs; how out of touch are these people and where is their involvement in the Muddy Studies?

    It was all very well Dr. Bhugra saying on IAI Madness Incorporated “I love David”, but.

    Was he really listening…?

    https://iai.tv/video/madness-incorporated

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