A 2016 RxISK post discussing how common post-ssri sexual dysfunction (PSSD) might be, highlighted Colpi et al., 1991, and Yilmaz et al., 1999 showing fluoxetine and clomipramine, both serotonin reuptake inhibitors, reduce genital sensation. These studies feature in our 2018 paper: Enduring sexual dysfunction after treatment with antidepressants, 5α-reductase inhibitors and … [Read more...] about New Test to Confirm a PSSD Diagnosis
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Withdrawal, PSSD and Cholinergic Drugs
Health Warning I don’t know a great deal about the issues in this post. Experts by Experience and The Marketing of Anticholinergic Maleficence along with Psychotropic Drug Follies will give some feel for the background that makes it difficult to be certain about anything linked to the cholinergic drugs. The Past Present and Future article will need to be downloaded to take to … [Read more...] about Withdrawal, PSSD and Cholinergic Drugs
Experts by Experience and Nobel Prizes
In the mid-1980s, I gave a very nice man, an in-patient, weekend leave. He hung himself. Everyone was shocked. The drug I’d put him on was the trigger to his suicide. Soon after, a medical resident called me to a case she was handling. She seemed exceptionally impressive, so I was surprised to hear afterwards she was taking an antidepressant. She told me about the … [Read more...] about Experts by Experience and Nobel Prizes
Visual Snow: A Looming Epidemic
There have been multiple RxISK posts on visual problems linked to SSRI use, starting a decade ago with Keeping an Eye on the Ball and most recently Visual Snow Protocol and New Study of Antidepressants and Vision Problems. Visual Snow can be episodic linked to migraine, or continuously present when triggered by antidepressants. When visual problems - palinopsia, enhanced … [Read more...] about Visual Snow: A Looming Epidemic
What Counts? A Tale of Good and Evil
This title plays on words. Counting suggests numbers but also hints at values. This talk hinges on a clash between a worldview centred on numbers and one centred on values. The slides and text are below. A video record of the talk is here - What Counts? Slide 2: One of these two is on an antidepressant and unable to make love. Like drug induced Homicide, … [Read more...] about What Counts? A Tale of Good and Evil
How the Safety of Drugs was Destroyed
Emer Cooke, the CEO of the European Medicines Agency (EMA) is Irish. This is Dublin's famous Halfpenny Bridge which for some reason features in an article outlining the history of the phrase Tail wags Dog which seems appropriate for what followed. I wrote to Emer recently about a bizarre letter I received from Kinapse - A Brush with EMA - who run EMA's medical literature … [Read more...] about How the Safety of Drugs was Destroyed
The Wild Doctor – Le Médecin Sauvage
The French playwright Moliere loved poking fun at pomposity especially when it involved doctors. In Le Bourgeois Gentilhomme, he pokes fun at Monsieur Jourdain, a pompous upstart, who has come into money and is taking on airs and graces. Translating gentilhomme into gentleman misses what the word meant around 1660, which was more like civilized, the manners which … [Read more...] about The Wild Doctor – Le Médecin Sauvage
A Brush with the European Medicines’ Agency
This post should be read in conjunction with Are Journalists the Answer to Clinical Medicines Cause and Effect Problem which is on davidhealy.org, or will be, and last weeks Clinical Details Confuse Expert Doctors along with Royal College of Psychiatrist's Suicide Note. Several months ago, I agreed to review an article by John Read analyzing the hundreds of antidepressant … [Read more...] about A Brush with the European Medicines’ Agency
Clinical Details Confuse Expert Doctors
Following the death of their 16-year-old son Romain, who had been put on paroxetine with Tercian later added, Yoko Motohama and Vincent Schmitt began asking questions of GSK, Sanofi, the French ANSM (Agence nationale de sécurité du medicament), and others. They set up two websites Antidepeffects.wordpress.com and Romainschmitt.wordpress.com. Romain’s case features on … [Read more...] about Clinical Details Confuse Expert Doctors
PPPD – Persistent Postural Perceptual Dizziness
This post is from R, whom I came into contact with at least a decade ago. She had significant SSRI dependence and withdrawal issues. And was very discombobulated by the difficulties she was having. Back in 1997 after a difficult and stressful house move I went to see my Family Doctor because I was getting a lot of headaches and panic attacks in crowded places. She said I was … [Read more...] about PPPD – Persistent Postural Perceptual Dizziness