RxISK

Making Medicines Safer for All of Us

Antidepressants

FDA Sued for Failing to Act on RxISK’s Petition

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In February 2018, we began work on a petition requesting warnings about post-SSRI sexual dysfunction (PSSD) and persistent genital arousal disorder (PGAD) to be added to SSRI and SNRI antidepressants. The academic literature on these conditions had been steadily increasing, and our latest case series on persistent sexual dysfunctions had just been accepted for publication - … [Read more...] about FDA Sued for Failing to Act on RxISK’s Petition

Ondine’s Curse: Can’t Live With or Without

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Ondine's Curse links closely to Balancing our Bodies and next week's Juggling our Selves. Ondine’s Curse sounds like a Greek Myths. Its not.  The story began taking shape a few hundred years ago and has been elaborated ever since - ending up featuring in The Little Mermaid and other stories. The standard version is that a faithless man is cursed by Ondine, a water-nymph, … [Read more...] about Ondine’s Curse: Can’t Live With or Without

Balancing Our Bodies and Our Selves

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Thanks to R who helped trigger this important RxISK post and some doctoring. . In July 2023, RxISK ran a post, written by R, giving an account of her Persistent Postural Perceptual Dizziness.  PPPD was new to us.  R had been in regular contact for a decade because of protracted withdrawal problems. Her problems came back in waves that were difficult to manage. She was then … [Read more...] about Balancing Our Bodies and Our Selves

Deprescribing – Where does Responsibility Lie?

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This post follows on from last weeks Potentially Inappropriate Deprescribing and has links to this weeks The Creation Narrative and God Complex. It brings up a painfully tricky point.  Reducing Medication Burdens is perhaps the most important task in medicine today. Many well-meaning folk are aware of and raising the profile of this need and attempting to work out how to go … [Read more...] about Deprescribing – Where does Responsibility Lie?

Potentially Inappropriate Deprescribing – PID

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This post is linked to An Archipelago of Realities on DH.org.  The link may not be clear when you start reading Archipelago but half way down it will be apparent. What is being said on Archipelago about SSRIs applies just as much to benzodiazepines here.   Geriatric medicine came into being in the 1980s and with it a new word – polypharmacy – a phenomenon particularly … [Read more...] about Potentially Inappropriate Deprescribing – PID

Transferring the Prize to the Research Fund

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The RxISK Prize was launched on September 12, 2017. It was a campaign to raise $100,000 USD which would be offered as a prize to anyone who could provide a cure for post-SSRI sexual dysfunction (PSSD), post-finasteride syndrome (PFS), or post-retinoid sexual dysfunction (PRSD). The possibility of a research fund had been considered, but despite having chased numerous leads … [Read more...] about Transferring the Prize to the Research Fund

Sex, Death and the Royal College of Psychiatrists

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The Guardian just ran an article on PSSD - It feels like we've been lobotomized. The following day they surprisingly had two articles on Singulair - Montelukast - hazards Safety fears over asthma drug after young children suffer severe side effect and A healthy kid dies and there has been no change’. For a paper that has not noticed a single hazard of a drug or vaccine … [Read more...] about Sex, Death and the Royal College of Psychiatrists

Fertility, the Moon and the Military

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For Millennia, the Moon has been linked to Fertility, Healing and Creativity. It was the Goddess for Fertility.  None of our ancestors, however, had to wonder if a Robot on the moon might have implications for Fertility. If you think last week's Lunar Landing of an Intuitive Machine Robot could have nothing to with Fertility – think again. We normally link medicine to the … [Read more...] about Fertility, the Moon and the Military