This is the first part of a two part series on clinical trial fraud from Johanna Ryan, with part 2 next week. Jo is RxISK's clinical trial and shoddy clinical practice sleuth - see The Maintenance Man. Recently the U.S. Department of Justice called attention to a small but worrisome crime wave. Health care fraud is a familiar feature of American life that may account for … [Read more...] about Ghosts in the Clinical Trial Machine
Antipsychotics
Farewell Marchino
Nearly a week ago a group of Italians sent this post written after one of their number gave up his struggle with PSSD and the system. We've been very slow posting it - partly because of the emotions it stirs. Its quiet beginning and contained fury at the end conjured up Marc Antony's speech after Caesar's assassination. I Come to Bury Marchino Goodbye Marchino.. Little … [Read more...] about Farewell Marchino
Antidepressants: Education and Disability Certificates
This post covers difficulties primarily on antidepressants that medicines can cause to people in schools or universities who end up unable to study or do course-work, as well as the difficulties people can have trying to get off medicines, a process that can be pretty disabling. The materials linked to this post are being put in your hands to run an experiment and hopefully … [Read more...] about Antidepressants: Education and Disability Certificates
Functional Neurological Disorder?
A recent RxISK post on SSRI triggered Movement Disorders - My Doctor Thinks I'm Faking It - put together by Stevie Lewis, attracted less attention than we expected. This may be because it featured strange movements and few of us figure we are in a good position to make sense of strange movements. The movements we featured don't make sense to many neurologists, even … [Read more...] about Functional Neurological Disorder?
Grey Hair, Rotting Teeth, Semi-Blind and Demented
The Human Body is not meant to be taking ‘stuff’ all the time, whether medicines or biohack stuff or whatever. Forget the image of a magic bullet that flies to the one spot where it is needed and causes no collateral damage, every medicine poisons. The trick is to use medicines only when the damage being caused by some condition outweighs the inevitable harms of the poison … [Read more...] about Grey Hair, Rotting Teeth, Semi-Blind and Demented
Starship Corona: Captain’s Log
The use of psychiatric meds in the U.S., already sky-high, is on the rise as a result of Covid-19. That’s not surprising – it happened after the 9-11 attacks, the 2008 crash and other crises. This graph comes from “America’s State of Mind,” an April 2020 report from Express Scripts. In the month from February 15 to March 15, prescriptions for depression, anxiety and … [Read more...] about Starship Corona: Captain’s Log
Covid and the Market in Research
There are 3 bits to this post - an interview with Joan-Ramon Laporte. An article by Ariane Denoyel and a Q and A with Laporte and Healy. Laporte Interview As part of a series for ROAR Magazine, Frank Barat has run some striking interviews about aspects of the Covid pandemic not usually mentioned. Here is Joan-Ramon Laporte talking about the market in … [Read more...] about Covid and the Market in Research
Medications compromising Covid Infections
IN THE MIDST OF THE SARS-CoV-2 PANDEMIA, CAUTION IS NEEDED WITH COMMONLY USED DRUGS THAT INCREASE THE RISK OF PNEUMONIA. Joan-Ramon Laporte, M.D. Emeritus Professor of Clinical Pharmacology, Department of Pharmacology, Therapeutics and Toxicology Universitat Autònoma de Barcelona. Fundació Institut Català de Farmacologia. WHO Collaborating Centre for Research and Training … [Read more...] about Medications compromising Covid Infections
Ecclesiastical and Pharmaceutical Risk Benefit Calculations
The Catholic Church has been convulsed in recent years by sexual abuse scandals. There are two aspects to this. One has been the harm inflicted on children from the abuse but in many instances as much if not more damage has arisen from the secondary harms these children and later adults have incurred in their efforts to get believed. The second aspect has been the Church’s … [Read more...] about Ecclesiastical and Pharmaceutical Risk Benefit Calculations
Montelukast, Fluoroquinolone, Psychotropic Withdrawal & Toxicity
Last week's post on Montelukast Withdrawal Syndrome has attracted comments at a higher rate than any prior post in 7 years of RxISK posts. It followed a post on Asthma causing Suicide and Homicide two weeks previously, which had links to the QuarterWatch 2015 report of adverse events in children fingering montelukast and suicidality as the second most common pediatric … [Read more...] about Montelukast, Fluoroquinolone, Psychotropic Withdrawal & Toxicity