Perhaps linked to this January 23rd news:
MONTREAL — A team of researchers from the Montreal Heart Institute believe they have found an effective weapon against COVID-19: colchicine, an oral tablet already known and used for other diseases.
Full Article HERE
We had an enquiry from a reader – can we let him know the 100 commonest side effects listed for Colchicine.
This was too good an idea to keep simply as a response to him. It felt like a post in its own right.
Behind the scenes, you have RxISK team members who figure hydroxychloroquine may be more effective for Covid than the powers that be have been willing to concede if only because the powers that be have gone to such extraordinary lengths to diss it.
See Meryl Nass here. Difficult to avoid thinking conspiracy here except perhaps for the fact that if hydroxychloroquine is useful for coronaviruses why haven’t we been using it all this time.
Hydroxychloroquine might be useless but there still could have been a conspiracy to make as much money from the perhaps even more useless remdesivir as possible before something effective turned up.
Is Colchicine effective? Who knows. At the moment we have a press release. There seems like there has been a trial.
It is possible that an ancient drug like this – the history is worth Googling – works.
If it does, it will be interesting to see how the attack dogs let loose by those with a lot of money at stake go about their business. Hydroxychloroquine playbook or something else?
The Full list of 100 most common side effects is HERE
The first point to note is colchicine is an old drug and not widely used so its likely relatively few people bother to report now. There are only only about 12% of the reports on it there are on Zoloft-sertraline for instance.
A second point is that with reports like this is the reporters or FDA coders can code kidney problems under many different headings – seven in this case. So it seems to make sense to do some amalgamating.
The commonest problems are gut problems – diarrhoea, abdominal pain, vomiting, nausea and potentially others like haemorrhage and constipation.
Abdominal problems come to at least 4,200 reports – 25.4 % of the total.
Kidney problems are the next most common group. These come to 2960 reports 17.8% of the total.
After this comes a series of reports about the drug being ineffective or making things worse. This is true for all drugs – antidepressants regularly make depressed people worse. In this case the problem may be fluid retention in joints – fluid retention definitely also happens.
These comprise 2600 reports – 15.8 % of the total.
Of interest to all RxISK readers is does colchicine cause suicide? Yes it probably does. This is one to add to our list of 300 Drugs that cause Akathisia and Suicide.
There are at least 1300 reports, 7.8% of the total that are consistent with this.
Of equal interest to RxISK readers is does colchicine cause sexual problems? Well searching through the top 900 reports there doesn’t appear to be anything to do with sex. This may be because the people who ordinarily get colchicine aren’t associated with sex.
It may take some young readers interested to warn off Covid by taking Colchicine to make the discovery and report back. What if it cured PSSD or PGAD?
Pain of various sorts happens in 2,840 cases – 17.1% of the total
Blood cell changes (anemia, neutropenia or pancytopenia, or liver enzyme changes) account for over 1900 reports or over 15% of the total reports.
Fatigue happens in 1450 cases – 8.7% of the total.
Skin problems happen in 1210 cases – 7.25% of the total
There are over 1200 reports of cardiac problems – 7.2% of the total. Adding raised blood pressure and stroke to this mix increases the totals to 1856 and 11.1% of the total.
There are 732 reports of Drug Hypersensitivity problems – 4.4% of the total.
Given the huge under-reporting on this drug and its possible use in people never exposed to it before if the claims that it can help in Covid catch on, we may be about to find out a lot more about what it does.
Anyone taking Colchicine is invited to Report to RxISK.
Who knows what might come to light.