Mentally Hijacked by Doxycycline

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November 22, 2021 | 8 Comments

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  1. Doxycycline has been authorised as an anti-malaria drug for more than 50 years. It is also prescribed to treat bacterial infections and skin disorders. An MHRA spokeswoman said they had reviewed the “suspected association between doxycycline and psychotic disorder” after the coroner’s report and work was “continuing”.

    Alana Cutland: Parents’ shock over malaria drug behind plane fall

    https://www.bbc.co.uk/news/uk-england-beds-bucks-herts-54818652

    The parents of a student who fell from a plane after a psychotic reaction to an anti-malaria drug were “shocked” to find its side effects were “virtually undocumented”.

    Alana Cutland, 19, from Milton Keynes, died after the fall in July 2019 in Madagascar.

    A coroner has asked for a review of the information sent out with doxycycline.

    The Medicines and Healthcare Products Regulatory Agency (MHRA) said it was gathering “further information”.

    https://www.judiciary.uk/wp-content/uploads/2020/10/2020-0151-Response-from-the-Medicines-Healthcare-Products-Regulatory-Agency_Redacted.pdf

    Overall, these spontaneous ADR reports provide limited evidence on which to base a thorough assessment of causality between doxycycline and psychotic reactions. While under-reporting is a common problem with spontaneous ADR reporting, given that in the context of malaria prophylaxis, doxycycline is often given to healthy people, it may be that we would expect to see more cases of a serious reaction like psychosis if it were a true ADR for doxycycline. In addition, there is no established biological mechanism to explain an association between doxycycline and psychotic reactions and there is little in the way of published literature suggesting a causal link, including a lack of any well-controlled studies.

    The CHM Pharmacovigilance Expert Advisory Group advised that overall, the evidence to support a causal association between doxycycline and psychotic disorder was limited considering the cumulative exposure to this drug in the UK which is likely to be in the order of tens of millions of people. The PEAG advised that prior to the possible addition of psychotic type reactions in the doxycycline product information, which may cause patient alarm, further data is needed to enable a more robust assessment. The EAG recommended that the marketing authorisation holder (MAH) for the brand-leader doxycycline product should be requested to propose how this additional data may be collected, for example by investigating the feasibility of conducting a study using electronic healthcare records which compares rates of psychotic reactions following doxycycline, with another antibiotic.

    Action being taken by the MHRA …

  2. MHRA: “suspected association between doxycycline and psychotic disorder”.

    I’d rather be ‘alarmed’ than HARMED.
    Why not recommend that prescribers are aware of this concern and increase reporting. How is an acute confusional state as an ADR to doxycycline to be differentiated from ‘First Episode Psychosis’. In the tragedy that destroyed the life and health of our loved one: an SSRI (inappropriately prescribed) resulted in acute, intense AKATHISIA which was misdiagnosed as ‘psychotic depression’.

    “Psychotic depression is vanishingly rare compared with treatment induced akathisia”.

    To accumulate further evidence for Doxycicline induced ‘Psychosis’ it would be
    necessary to avoid misdiagnosis as a Psychotic presentation, which will be followed by inappropriate detention, forced drugging, physical, psychological and emotional injury and a kaleidoscopic collection of Psychiatry labels for Life.

    Why not insist that all who are labelled as first episode psychosis have a detailed prescription dug history entered into a centralised, anonymous, computer data base held by an MHRA more committed to patient safety? If all those so-labelled had an identifiable history of doxycycline ingestion, SSRI/SNRI ‘Rx’ (or dose/product change) and/or other akathisia inducing/neurotoxic drug ingestion identified: further evidence of association may increase awareness of this ADR. It may also reduce unforgivable psychiatric misdiagnosis and subsequent loss of all human rights.

    The use of the term ‘psychotic disorder’ by the MHRA surely invites misdiagnosis?

    • “To accumulate further evidence for Doxycicline induced ‘Psychosis’ it would be
      necessary to avoid misdiagnosis as a Psychotic presentation, which will be followed by inappropriate detention, forced drugging, physical, psychological and emotional injury and a kaleidoscopic collection of Psychiatry labels for Life.

      Why not insist that all who are labelled as first episode psychosis have a detailed prescription dug history entered into a centralised, anonymous, computer data base held by an MHRA more committed to patient safety?”

      Do do this will require psychiatry to admit what it resolutely refuse’s because it knows all the harm it has created along with pharma. Everyone in a psych ‘hospital’ is on antipsychotics no matter what the diagnosis and most are on high dose and have akathisia – this is a major human rights crime going back a long way.

      The agencies set-pup to over see psych hospitals, to date, have only covered up what is happening – they are not exposing and shutting down these operations which lead to this:

      https://www.expressandstar.com/news/local-hubs/sandwell/west-bromwich/2021/03/26/man-absconded-from-mental-health-facility-before-being-found-dead-on-motorway/

      • “Everyone in a psych ‘hospital’ is on antipsychotics no matter what the diagnosis and most are on high dose and have AKATHISIA”. Press Report: ‘HE WAS PACING AROUND’ —–(my emphasis).

        • “Mrs Perry said Hallam Street Hospital is not a psychiatric intensive care unit, that there are patients who choose to go there and those who are detained for treatment but it is “absolutely not” a prison.”

          Also worth noting from the article ‘it’s “absolutely not” a prison’ but negate to inform the public there are two locked doors to the outside world. After being informed of this recent atrocity I sent the CQC and the trusts governance support manager a link to akathisia on here and this quote:

          “as David Foster Wallace put it before he died:

          “The person in whom its invisible agony reaches an unendurable level will kill herself the same way a trapped person will jump from the window of a burning high-rise… The terror of falling from a great height is still just as great… It’s not desiring the fall, it’s the terror of the flames… You’d have to have personally been trapped and felt flames to understand a terror beyond falling”.

          They have a CQC report being published on 2nd Dec I bet they will be given a good rating.

  3. Chris ,It’s going to be ‘interesting’ to see how Austria enforces it’s mandate that all citizens are to be vaccinated starting in Feb 22.
    Will they take lessons from psych hell holes on how to pin people down and forcibly inject them… In Russia dissidents are forced into Covid ‘hospitals’ and forced to ‘accept’ vaccines. It’s not a huge step to ‘diagnosing’ people who decline to be vaccinated as mentally ill. Potential harms from enforced vaccs plus harms from enforced psych meds – in a totalitarian nightmare in a world led by psychopaths such as the Austrian chancellor who wants ‘turn the screws’ on unvaccinated citizens. The police would always be willing to assist as shown by the often heavy handed surveillance and fining of citizens in UK during ‘lockdowns’ and firing on and water hosing of protesters throughout Europe presently.

  4. Not so long ago, certainly it increased after the menace Tom Burns psych persuaded the government to introduce ”treatment’ in the community , forced ie depot injections, people in areas with independant ‘user-survivor’ networks set up safe houses where refusniks were looked after by friends. A few psychs would give advice off the record on meds but many were knowledgeable anyway. . The nasty campaign by politicians and their allies against people who refuse vaccs scapegoats and set citizens against citizens so we take out eye off the way more and more rights are being abused – in our name. If it goes too far it’s likely no-vacc safe houses will be set up and for sure more false proofs of being vacced will become a more lucrative business than it already is.. It is sad that groups who know first hand what discrimination can lead to are keeping pretty silent about the creeping violations . It;s not just a question of taking or not a vaccine but of to some extent grieving as well as resisting with protests and riots all across Europe against the undermining of democracry.

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