The Persecution of Heretics

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December 10, 2014 | 4 Comments

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  1. Interesting.I have yet to find a published report of adverse effects of biologics.Apparently no one is willing to publish the long term effects of these drugs.I have sen a number of patients with terrible side effects and sent a letter to the editor .No reply and no publication!

  2. Dr Joanna LeNoury found this Cochrane Review of adverse effects reported in trials:

    Singh JA et al (2011)
    http://www.ncbi.nlm.nih.gov/pubmed/21328309

    It makes some good points — but mainly about the failure of the controlled-trial literature to come clean about the nature and extent of the side effects.

    As far as case reports, well, that’s interesting. I did a PubMed search of “lymphoma and adalimumab” just for kicks. Got several reports … all of them, it seemed, very recent, and all in what sounded to me like obscure specialty journals.

    Has criticizing Humira just been downgraded from a felony to a misdemeanor?

    http://www.ncbi.nlm.nih.gov/pubmed/?term=lymphoma+and+adalimumab

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