This post is close to identical to an article that has just appeared in the BMJ - Clinical Judgments, not Algorithms, are key to Patient Safety. Immediately on taking a selective serotonin reuptake inhibitor (SSRI), most people have some genital anaesthesia.1 This may be aggravated on withdrawal of the drug and can remain for years after treatment has stopped, constituting … [Read more...] about RxISK Manifesto
PSSD Patient Experiences
New paper "If you wish to have such “syndrome” continue what you are doing ... read obscure studies and reviews in obscure databases and I can guarantee to you that you will have it till the end of your life!" Anyone who has experienced a serious side effect from a medication will know how difficult the conversation with your doctor can be. In our new paper, “Post-SSRI … [Read more...] about PSSD Patient Experiences
Business Opportunity courtesy of Impeto Medical
Some months ago we had organised for 6 volunteers with PSSD to get tested for peripheral neuropathy, using a Sudoscan, made by Impeto Medical, who are based in Paris. By chance we found that there is a genital adaptor for the Sudoscan that has been in use for several years in Paris, leading to a publication over two years ago. Through a colleague, we got in contact with Dr … [Read more...] about Business Opportunity courtesy of Impeto Medical
Device Wrecks & Regulators?
RxISK is powered by people working behind the scenes - picking at threads and sometimes finding something rather different to what they expected. One of those who can't resist a loose thread is Suzanne Stevens, who has been interested in our Sudoscan problem. Many of you suffering with PSSD or related PRS, PRSD and PGAD conditions have been emailing Impeto Medical in Paris … [Read more...] about Device Wrecks & Regulators?
Ecclesiastical and Pharmaceutical Risk Benefit Calculations
The Catholic Church has been convulsed in recent years by sexual abuse scandals. There are two aspects to this. One has been the harm inflicted on children from the abuse but in many instances as much if not more damage has arisen from the secondary harms these children and later adults have incurred in their efforts to get believed. The second aspect has been the Church’s … [Read more...] about Ecclesiastical and Pharmaceutical Risk Benefit Calculations
Sudoscan Saga & Propecia/Finasteride Survey
Sudoscan Several months ago, we became aware of a device called Sudoscan made by Impeto Medical, based in Paris. It’s mainly used to assess peripheral neuropathy in the hands and feet. But the company also have a special adaptor for Sudoscan that has been used to test genital function and found disturbances where other tests haven't. This is custom-made and isn’t commercially … [Read more...] about Sudoscan Saga & Propecia/Finasteride Survey
Extinction Revolt?
Editorial Note: Following the Montelukast, Fluoroquinolone and Psychotropic post, there is a comment from Heather Roberts to which David Healy responded. The edited comments are here. This led to an email exchange between HR and DH which follows. Along with Wendy Dolin and her MISSD website (see above) and Billiam James' Akathisia Anthem, Heather and her husband David have … [Read more...] about Extinction Revolt?
Cis- and Trans-Drug Wrecks
After a Montelukast Withdrawal Syndrome post two weeks back, we had more comments than after any previous post - so much so that this seemed worth noting in a Post in its own right. After last weeks Transgender Meds, we have had fewer comments than after any previous post. This also seems worth noting in the form of a post. This is not so much a post as a series of notes … [Read more...] about Cis- and Trans-Drug Wrecks
Transgender Meds: A Call for Reports
This post is an invitation to report on drugs prescribed to transgender people. These include cross-sex hormones - testosterone for women, estrogen and progesterone for men, hormone-blocking agents like Lupron given to children with gender dysphoria to stop the physical changes of puberty, and other drugs like finasteride, spironolactone and birth-control pills prescribed to … [Read more...] about Transgender Meds: A Call for Reports
Montelukast, Fluoroquinolone, Psychotropic Withdrawal & Toxicity
Last week's post on Montelukast Withdrawal Syndrome has attracted comments at a higher rate than any prior post in 7 years of RxISK posts. It followed a post on Asthma causing Suicide and Homicide two weeks previously, which had links to the QuarterWatch 2015 report of adverse events in children fingering montelukast and suicidality as the second most common pediatric … [Read more...] about Montelukast, Fluoroquinolone, Psychotropic Withdrawal & Toxicity