Sensory Receptors, Small Fibres and Neuropathy
September 21, 2022 | 12 Comments

RxISK began in 2012.  One of its main goals was to offer people an opportunity to report problems they had on treatments – any treatment – and generate a report they could take to a doctor in the hope this might get the doctor to take their problem seriously. I had seen my first cases […]

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New Sex and Drugs Research Forum
August 24, 2022 | 4 Comments

RxISK Research Forum for Enduring Sexual Dysfunction RxISK is pleased to announce a new Research Forum.  This was trailed in a recent post  Our Love Life Needs you to be Wi(c)ked. Since this post we have had a lot of input from many folk offering to help out – mostly advising us to keep it […]

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Our Love Life Needs You to be Wiked
August 3, 2022 | 15 Comments

Our Love Life Needs You © Nina Otulakowski August 2022 RxISK regularly gets enquiries about what can be done to find an answer to the sexual dysfunctions following SSRIs, Finasteride and Isotretinoin –  PSSD, PFS and PRSD. RxISK and Sharks outlined the likely Endgame.  This outcome would be terrible – especially as its highly likely […]

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RxISK Research Fund and Prize
June 27, 2022 | 48 Comments

We need to clarify some things about the RxISK Prize and Research Fund.  The Prize was established RxISK Prize in 2017 – see The Golden Rule, RxISK No-Nos, Relationships, Stigma and Recovery, Campaign and Challenge. Some of us in RxISK have had a difficult few months attempting to set up a Research Fund for PSSD […]

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The Holy Grail: Searching for a Cure for PSSD
June 21, 2022 | 42 Comments

The Holy Grail © Nina Otulakowski June 2022 You need to click on the image to get the full effects. Post-SSRI Sexual Dysfunction (PSSD) is a debilitating consequence of taking serotonin reuptake inhibiting drugs (SSRIs, SNRIs, some antihistamines, some antibiotics, some analgesics and other medicines) that can leave people of all ages, and from all countries […]

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The Caste System in Medicine
May 2, 2022 | 9 Comments

This post is by Spruce who has been a regular contributor to these columns.  It follows from his comments on The Invisible Doctor and it adds to that post which has had a lot of comments since.  Humans seem to have a tendency to caste systems but most people would be surprised to think you […]

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Welcome to Mondor, Frodo
March 1, 2022 | 5 Comments

Quarantined Last October one of the key researchers on PSSD noticed a thread on Reddit about sexual dysfunction post vaccine.  Apparently the thread has been quarantined and you have to join the Reddit group to access it – this is likely true about a lot of vaccine related threads. Here are two testimonies that appear.  […]

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Leader with a Mandate to Eliminate Contagion
February 4, 2022 | 11 Comments

Breaking News Jorge Mario Moves with the Times Having been the first Head of State to introduce Mandates, Jorge Mario Bergoglio appears to have gotten the bit between his teeth and is now embracing (perhaps the wrong word) modern medicine rather completely. While one will surely come, there is not at present an mRNA  gene […]

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Post Minoxidil Syndrome
January 26, 2022 | 8 Comments

Greetings all, I want to thank RxISK for presenting this opportunity for me to share my experience with this drug and my persisting side effects from it. It all started in April 2021, I was an insecure eighteen year-old Canadian guy slowly losing his hair like many others out there. Desperate for a cure, I […]

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Is Recovery from Medication Possible?
January 14, 2022 | 38 Comments

In response to recent posts, especially A Time for PSSD, Laurie Oakley got in touch with the following thoughts.  Laurie has had a series of six posts on Pharmaceutical Rape on davidhealy.org starting in February 2015 but mostly from early January 2016.  These outline her own difficulties recovering from medication induced injury and the equal […]

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No sex please (we're on antidepressants)
Sex Please but We Are on Antidepressants
January 5, 2022 | 4 Comments

This anonymous post stemmed from a RxISK report, which came in following A Time for PSSD last week. If anyone else, female or male, has started an antidepressant before or early in puberty with things not working quite as a result – anything from being asexual through to intrusive uncontrollable orgasms – you can file […]

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A Time for Post SSRI Sexual Dysfunction?
December 28, 2021 | 13 Comments

This post has been put together by L who in the last few years has been an inspiration to many people suffering the ill-effects of a number of different drugs.  Like mythical heroines she has many different aliases.  When it comes to the harms done to us, behind heroes like Zorro or the Scarlet Pimpernel, […]

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Diagnostic Criteria for Enduring Sexual Dysfunction
December 19, 2021 | 11 Comments

Background We noticed that a lack of diagnostic criteria was increasingly being mentioned in the published literature on post-SSRI sexual dysfunction (PSSD). The condition was being described as difficult to diagnose because there was no commonly accepted definition. At the same time, a number of new websites and online discussions were appearing, many of which […]

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Prescribed Harms and Vaccine Hesitancy
October 18, 2021 | 48 Comments

In 2015, there was a series of posts on davidhealy.org Pharmaceutical Rape, Pharmaceutical Rape is not a Metaphor, Pharmaceutical Rape: Cast of Characters, Pharmaceutical Rape: The Good Patient, Pharmaceutical Rape: Doctors Still Know Best, Pharmaceutical Rape: Discrimination, Pharmaceutical Rape: Ending our Tolerance. The following year GlaxoSmithKline lawyers deposed me in the Dolin case, spending hours […]

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Mind Softens Warning about Sexual Side Effects of Antidepressants
September 13, 2021 | 11 Comments

Mind is a mental health charity based in England and Wales. For several years, their information on antidepressants has included a warning that sexual side effects may continue after stopping an SSRI or SNRI – Post SSRI Sexual Dysfunction (PSSD). We recently contacted Mind after noticing a change to the wording. See the emails below. […]

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Farewell Marchino
April 30, 2021 | 102 Comments

Nearly a week ago a group of Italians sent this post written after one of their number gave up his struggle with PSSD and the system.  We’ve been very slow posting it – partly because of the emotions it stirs. Its quiet beginning and contained fury at the end conjured up Marc Antony’s speech after […]

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Sex, No Sex, Sex, No Sex….
April 21, 2021 | 19 Comments

Accessible New Resource RxISK has a new resource – a literature resource.  PSSD Literature.  You can download any of these articles and take them to any doctor, lawyer or other person you see.  While in this area on RxISK, have a look at the other material under Tools. Anyone who becomes aware of any other […]

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Antidepressants: Education and Disability Certificates
March 22, 2021 | 38 Comments

This post covers difficulties primarily on antidepressants that medicines can cause to people in schools or universities who end up unable to study or do course-work, as well as the difficulties people can have trying to get off medicines, a process that can be pretty disabling. The materials linked to this post are being put […]

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MAiD in Canada: Treatment Resistant Depression
February 19, 2021 | 15 Comments

See accompanying MAiD in Canada and Sex. Illustration: Meds © created by Billiam James The provision of Medical Assistance in Dying (MAiD) is under review in Canada with debate about access for patients with mental illness. An amendment to the draft legislation eliminating the exclusion of people with mental illness was proposed by Senator Stan […]

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Health Canada warns about Persistent Sexual Dysfunction after SSRIs & SNRIs
January 18, 2021 | 5 Comments

Health Canada has just concluded its review of persistent sexual dysfunction after stopping SSRIs and SNRIs. Let’s look at some of the background. January 2019 On 25 January 2019, we were contacted by the Marketed Pharmaceuticals and Medical Devices Bureau at Health Canada. They had become aware of our 2018 paper, “Enduring sexual dysfunction after […]

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I Am Your Patient Too
December 24, 2020 | 25 Comments

This 2020 closes in the middle of Covid19 and with the package leaflets of SSRI and SNRI antidepressants just updated in Europe with a new but evasive Warning: ‘Cases have been observed where symptoms of sexual dysfunction have persisted after discontinuation of treatment‘. Doctors, did you notice? Here I am.  My sexual symptoms caused by […]

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$100K and a List of Doctors
December 14, 2020 | 43 Comments

$100,000 target reached We are pleased to announce that the RxISK Prize, which was launched on 12 September 2017, has reached it’s goal of $100,000. This consists of money that has been donated as well as pledges from two generous donors who have provided written agreement to hand over money in the event that a […]

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TRP Drugs and Herbs for Withdrawal and PSSD
November 25, 2020 | 25 Comments

We first mentioned Transient Receptor Potential (TRP) Channels/ Receptors in several RxISK posts about withdrawal and they feature on the RxISK Complex Withdrawal Page under Ion Channels.  The table on that page gives a fascinating list of herbs and other compounds that could conceivably play a part in stabilizing people who are having withdrawal problems. […]

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Where’s Anonymous?
September 7, 2020 | 13 Comments

The following email arrived last week from someone who is unknown to me – has never filed a RxISK report about PSSD, never contributed to the RxISK Prize, never previously been in touch that I know of – at least under the name offered – doesn’t sign off, and is unwilling to engage in a […]

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RxISK and Sharks
August 23, 2020 | 32 Comments

  Two posts last week on RxISK Biohacking and david healy Stormy Weather raised issues about the Enduring Sexual Dysfunctions (ESD) linked to SSRIs and related drugs (PSSD and PGAD), finasteride and related drugs (PFS), and isotretinoin (PRSD). In the biohacking post both sides of the “debate” were concerned about the people with these conditions […]

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Bio Rip-off, Bio Delusions, Bio Hack?
August 16, 2020 | 81 Comments

This ambiguous picture comes up when you search under grave robbing – nothing you can make money out of is sacred.  But its entitled grave digger. Digger, robber, it can be hard to tell. We had an email a few days ago about a young man desperately seeking help who had in good faith took […]

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Sexually Confused or Chemically Imbalanced Cosmopolitan
May 13, 2020 | 24 Comments

April’s Cosmopolitan features How Depression Stole my Orgasm – an article on Sex for sure… but Sex and Depression or Sex and Antidepressants? It’s worth downloading the full article and telling us what you think the message is. It opens with some pretty clear examples of how SSRIs have immediate effects on sex and can […]

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Catch San Marino if you Can
May 4, 2020 | 28 Comments

There have been some major developments on the RxISK Prize front. First we are hovering around the $66,666 point – depending on how exchange rates go we may be wandering back and forth over this line as I write. More important however is that San Marino has raced out in front as the donor leading […]

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Causes Sexual Dysfunction, Suicide and Birth Defects?
March 3, 2020 | 35 Comments

Everyone who reads RxISK posts will know that SSRI and related drugs (some antibiotics, painkillers, antihistamines and most antidepressants) can cause sexual dysfunction. This has been known since 1961. And that they can cause suicide.  This has been known since 1959. And that they can cause birth defects. The first publication by an Australian obstetrician, […]

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The Politics of PSSD
February 18, 2020 | 35 Comments

Members of the British parliament In October 2019, we were contacted by a British PSSD sufferer who had done some excellent work in getting his Member of Parliament (MP), Steve McCabe, interested in the condition. We were informed that Mr. McCabe wanted to get a large group of MPs together to try and get some […]

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