Accutane: 30 Years of Trading our Sex Lives for Clear Skin

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December 10, 2013 | 113 Comments

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  1. Very appropriate article. If you like sex even a little bit, know that that enjoyment could all be taken from you if you take Accutane. Sexual dysfunction is pure hell. This warning absolutely needs to be added to the paragraph of side effects on the label. People need to know that this is a possibility. If you’ve experienced this side effect, please report it through the FDA MedWatch program and on this website.

    • yes, I am experiencing it, ive been using Acnetrex since Nov.2013. Beforehand, I can say that I have that extreme libido, I am thinking of myself as a maniac but recently I am noticing myself as a blunt person. I am experiencing erection but its not lasting. I have the desire but my body is not responding. I wanna masturbate but my thing is just that flaccid.

    • I’m a femal, 31 yrs old now. I have sexual dysfunction since 7 yrs when I took accutane for 6 months. I have now zero libido & zero sensation. I cannot find any treatment and cannot marry.
      I became like a robot without any feeling after I was very horny.

      • I am Traci. I am 32 yrs old n was also on Accutane at a young age. My question is have u had children? I’ve been wanting to be blessed with a child but im starting to think Accutane is the reason i cant get pregnant.

  2. I was never told that accutane reduces growth hormone and testosterone levels before taking it, 2 things I really needed at the age of 17. Derms need to stop sugar coating this poison and tell patients how dangerous accutane really is. The drug accutane destroyed my life please don’t take it.

  3. It ruined my life the same way. Became impotent at age 16, 20 years old now. I have felt DEAD for 4 years now. No energy in my body, aching joints, a penis that no longer works, a brain that feels severely damaged. Go look up accutane. You learn later that this poison they give innocent children that just want their acne to go away is actually chemotherapy designed for brain cancer. HOW DELIGHTFUL. DON’T EVER TAKE THIS POISON IT WILL RUIN YOUR LIFE. AS STATED ABOVE, YOU WILL NO LONGER FEEL HUMAN. I have hope though. I am on my journey to ingest cannabis oil because i have learned how extremely medicinal it is and believe it may just be the cure for all these horrible side effects.

    • If anyone want to talk about problem, erectile dysfunction, problems after taking accutane can do that on mail: axehector@hotmail.com, I have lot of experience about that problems, and we also can exchange some personal experiences what i really want to do. (Everything anonymously of course)
      Regards

      • Hi Ivica,

        I am sorry to hear about your problem.

        I would like to learn from you how you have got better please and your experience ?

  4. Accutane has ruined my life. Accutane killed my penis is the best way I can describe how I feel sexually. Aside from impotence, I have very very low libido. Other severe and chronic side effects include: Major depression, anxiety, hair loss, dry skin, aching joints, and the list goes on. I cannot believe that the FDA would allow for a poison like this to remain available for so long. It’s because they care about the money, not your health.

    Derms are ignorant, most of them. Google will provide you with much better solutions to your skin problems than any Derm can, one example is Acne.org. Do not trust someone with your health just because they wear a white coat. Remember, the reason we are all suffering these, very likely, permanent side effects is because we trusted our Derms in the first place.

    It’s been 10 years for me without a resolution to ANY side effect that occurred as a result of Accutane.

    I have not given up. I will continue trying to cure myself of these life robbing side effects. I have tried very many supplements and other protocols to try to heal my body, unfortunately so far to no avail; Sometimes Accutane damage seems too powerful. But I’m not giving in, and neither should you. We all need to work together and try different (safe) options to heal ourselves. And if something works, we CANNOT be selfish about it, we HAVE to broadcast the possible cure on the internet EVERYWHERE we can so that we can give hope to the significant number of Accutane victims out there.

    Finally, DO NOT wait for someone else to provide you with the solution. Do some research, experiment safely – no more pharmaceutical medications! And try to find the cure to the possible indefinitely lasting side effects of Accutane yourself. Imagine there is no one out there but you, and if you don’t help yourself, then you will forever be trapped in a poisoned body.

    We can do it. But we all have to do some researching and trials and errors with regimes, natural supplements etc., whatever we can to reset our bodies.

    Get started right now. If we all waited for someone else to find ‘the fix’, then we will never recover.

  5. I’m a 16 year old male that has always had a high libido and never had any problems getting hard, even off of just thoughts of women. I’m currently on my first course of the drug Isotretinoin, coming upon the end of my second month taking a 40 mg / a day dosage.

    I have already noticed the size of my flaccid penis shrink. My boners are too quick to fade away. It’s never been this way in my whole life. Even when I was about 9. I was always able to obtain an erection with ease. It’s getting harder now, and I am noticing it. I’ve told my mom about it and she thinks I’m just being paranoid.

    My next appointment with the derm is in 2 days. I’m going to give it a shot at confronting them what the little brownish-orange pill is doing to my body. My acne has faded a little bit, but I still get little pimples. All the cysts are almost gone. My penis doesn’t seem to be working the way it was before I was prescribed this drug.

    I would take severe acne over a broken penis any day. Your penis is what makes you a man. Without it, what do you do? I’m not standing for that. I’m praying that stopping this early into the course will help me. I’m praying that it is not too late.

    My girlfriend noticed it one time before we had sex and thought it was her. I didn’t know why that was happening until I thought of it a couple days ago. None of this happened until I took this drug. My flaccid penis was never as small as it has gotten in the past 2 weeks, and I noticed it. I started to worry about it. I decided to google it not too long ago, and to my surprise, I was not the only one.

    There was story after story and post after post about people having the same exact problem after taking the drug Isotritenoin (Accutane). Most of them had these problems for over 5 years. That’s something I cannot live with. My sex life means a lot to me. It’s a big part of my life. I enjoy it. I can’t let a drug that I was unaware can cause such a destructive effect on my body do this to me.

    I pray that I will not be effected as much after I stay off the drug. I’m quitting my course about half way into it. I pray it is not too late.

    Good luck to all of you suffering with this problem out there.

    – Dylan

  6. I’ve got to share my story because hopefully it can provide a little hope to sufferers. I took 3 YES 3 courses of accutane starting my sophomore year in high school with the last occuring during college. From my junior year of college (20 years old) until recently (24 years old) I had many occurences of being unable to obtain an erection for sex HOWEVER I could get it up masturbating at times. This obviously really stressed me out and had me pretty depressed at times. By age 23 I had become content with a sexless life because there are worse situations in the world. At age 24 I met a girl who I fell in love with and almost ruined the relationship because I kept flaking on her for fear of failing in bed and her not liking me. I finally told her and I went to the doctor and got viagra/cialis. They worked wonders and after a while we began trying without them and HEY, with her patience and love, it fucking worked…I’ve been having drugless sex for half a year now. The pessimist in me says that maybe it was all mental for all those years but I had been having sex before no problem and lost it out of nowhere. The optimist in me (i’m an optimist) says don’t lose all hope because there are success stories like mine. Prior to this I did tons of research on this so I am no amateur to the plight, medical diagnosis, etc. If you have any questions you can email me at LeJclair101210@yahoo.com. I’ll be happy to try to answer any questions. Regardless, live life to the fullest even if you can’t have sex, there are other things that can bring joy in life and it could ALWAYS be worse.
    Best regards,
    John

    • John, your story and mindset is great to hear and inspiring…I am very happy you stayed optimistic and things are working out for you. I have Post Finasteride Syndrome, persistent side effects (sexual, mental, physical) from taking Propecia and appreciated reading your post. I am trying to stay optimistic and healthy in my lifestyle (diet, exercise) and just keep living life also.

      Take care,
      Brendan

    • Hey everyone!!

      So I chose to reply to this, rather than just post something because it was so relevant! The only difference is, I’m female!!

      I was on Accutane and lost my libido. I had the hottest man (or at least I’ve always thought he is) and sex was great until I started the medication. Slowly, I lost my libido. What kind of 17 year old girl isn’t horny? It freaked me and my boyfriend out and we fought for years. You see, at the time I didn’t realise it was the Accutane, because even once I stopped the medication (because I got very emotional, aggressive and depressed) I was still not horny, even though all the other side effects went away quickly.

      The great news is that, like John, patience is the answer. Except, even BETTER, is that I never went on medication. We just kept trying and using lube and one day he suggested we watch porn together. And since that day I’ve felt like my 16-year-old self (I’m 24 now). Yes it sucks and, if you haven’t taken Accutane, then don’t. But to those who have, don’t worry. All is not lost and it’s not permanent!! Just don’t give up. Because giving up is giving in, and you are NOT going to accept a life with no libido!! You can do it 😉

      Hope this helps guys!!!

      • My dermatologist just recommended isotretinoin for me to take for my cystic acne. Reading all this is completely freaking me out. I think I’ll try natural remedies first!

  7. Hey,

    I had been on 30 mg Sotret back in 2010 for just 2 months. Nothing happened for 2 years. After 2 years I developed sever back pain,( may be bcz of some other reasons.) However, alongside back pain developed knee and elbow pain as well. My Orthopedic had even done my CT scan to declare nothing is wrong. The pain was unbearable sometimes but is non existent away in the summers. And I am feeling pain just in 2 areas apart(from back offcourse) for a limited time.

    My question is that even after 2 years of no effect at all, can this light doses of accutane still be the reason for my joint pain? The peculiar thing I feel pain only when I sit idle for long duration. So is my pain due to wrong lifestyle?

    Kindly help in diagnosing this issue (as doctors are in total denial of any such link)

    • Vivek

      Go into RxISK and enter isotretinoin and look at FDA reported side effects. There are nearly 1400 reports of back pain and more for back injury. So it certainly looks like back pain is possible, although whether delayed like this is less clear to me

      David

      • My daughter had low dose isotretoin over a longer period than usual (several years) . This was prescribed by a dermatologist for acne. It worked for the acne but a pre-existing small benign tumour (a teratoma which often contains skin &hair) of one ovary enlarged over the following 2 years. This caused acute pain and she was admitted as an emergency to hospital where it was removed surgically. I think it is likely that the increased size of this tumour was caused by isotretoin.

  8. Hi,
    I can’t believe how fool I was, not searching and learning more about accutane, before starting my treatment. This drug ruined my life. I was never the happiest person in the world, or an innate optimistic, but lord did I have a high libido. I neger had sex until I was 24, being raised in a very rigid and square fashion, my parents expected me to stay virgin until marriage! But, I started developing cystic acne, at 16. And tried everything u can think of,but it wouldn’t go away. I was 23 when I finally started on accutane, felt the wonders of the drug after the first two weeks of treatment. Even my bulbous tipped nose shrinked. I felt beautiful and my skin was flawless. Was too busy looking at my finally clear skin in the mirror , to notice the slow but consistently increasing signs and symptoms of what would change my nonexistent sexual life forever. I used to get wet just holding hands, just smelling the guy I liked, and even being oon the edge of orgasm while kissing passionately . All of this without ever having penetration. A I was on my last weeks of accutane I met a guy , lost my virginity and it was ok. Never had an orgasm for the 14 months the sexual relationship lasted. I thought it was due to the fact that he had a gf, and I fel used. I still could have great orgasms by masturbation.the relationship ended , I was still feeling aroused and excited at times , that I never noticed three frequency of sexual thoughts and desire were slowly decreasing, I wasn’t masturbating so often. In my lay teens an early 20s , I’d masturbate on average about 3-6 times a day, having really vivid fantasies I’ll come in no time! Idk if I should feel embarrassed about this , but is nothing compared to the pain I feel now, to admit that I am completely numbed in my genitals . I never have felt the pleasure of penetration, I didn’t realize that by the time I had sex for the first time, accutane had already ruined my sex life , before it even started. It’s been 9 years now , I have only had an other sexual partner, who is my husband to this day, and he thought because of my inexperience it was hard to me to adieu orgasm. The fact is, with his patience and love , I now can have orgasms by oral sex, manual stimulation and also using a vibrator. I apologiz for being I specific, but is necessary to explain every single detail, so no other women have to bear this heavy cross. It takes TOO much stimulation for me to achieve orgasms. In a scale from 1-10 i would say they are from 1-6, 6 being the strongest. But I miss the sky rocketing, mind blowing orgasms I would By masturbation , I wish I could have share that with a partner. I feel nothing with penetration, sometimes is painful, I have severe vaginal dryness, I used to have to wear protective pads , I had such a high sexual drive I would get wet at the minimum stimulus fom an attractive guy. Today, I barely think about sex. I used to orgasm from seating and peing on the toilet just with the passing of my uring caressing my outer lips, it would tickle, and then just thinking about penetration while peing , would give me my secret peing orgasms in no time. I was a lucky girl. Today all that is gone , and the only reason I find I’s accutane. I have no libido, or very low if anything, I don’t even feel sexual excitement while kissing my husband, Andes just like if something cut the nerve that provides sensations to my genitals. I feel mutilated, I hate myself for waiting too long to enjoy sex, cause now I understand that it is your right, and not even bad parents like mine, should have decide over your sexual rights, cause now it’s gone and I never even got to enjoy it with a partner. Don’t get me wrong, I can have an orgasm with so much concentration and working really , really hard on it, but that tumescent warm sensation of the blood flowing to my genitals, the pleasure of my outer and inner lips expanding in response to this increasing blood flow, that anticipation and desperate desire for penetration, and the certainty of crazy pleasure awaiting for me as soon as my vaginal walls would expand to host that desired hard penis, is all gone:(. I used to try to delay my orgasms, just in order to achieve even a more intense one, now, I am lucky if I can come once. Bland boring orgasms. Is so sad, that I try not to think about it, other way I’d be majorly depressed. Its hard to explain neat happened to me, but I did my best.
    Please, please, stay away from accutane, try everything else but not this drug.
    Gaby

    • Your problems with lubrication may not be due to accutane, have you had your estrogen levels checked or considered a topical estrogen creme? The hyperexcitability of your orgasmic response is almost suggestive of nerve entrapment either from a tarlov cyst, pudendal nerve in alcocks cannal, or from the musculature of the pelvic floor (check out a headache in the Pelvis). Changes in sensation on a toilet seat are classic for this. You may consider contacting Dr. Irwin Goldstein in San Diego.

  9. Hello everyone,
    Enough of taking on Accutane. I am a victim too.
    Please share the treatments that you have taken and the success in those treatments.
    I wnat to know what accutane has done to me so that Doctors can the treat the cause.
    Now all that my doctor has been giving to me is anti-depresents, nerve builders and viagra for sex.
    It is one dimensional our problem is different and we need a different ED treatment.

    • You should look into the side effects of any antidepressants you are taking. Some (many) antidepressants cause the same thing.

  10. Accutane IN MY OWN expierience made me very panic prone towards the end . Especially when on 2 pills a day . The problem wasn’t getting it up the problem was the mental state it puts you in . Depression , confusion , and a partial decrease in flaccid size and lack of normal libido. These aren’t permanate and I treated it by refraining from masturbation an let my libido get stable. Then I was okay . As far as anxiety goes . Once you figure out what causing your impotence (anxiety) you generally get a grip on yourself and cure it. I haven’t had any long term side effects after either .

  11. HI guys! I just take four pills of ruacutan and instantly felt the effects in my erection and i immediately stop. BUT I COULD SOLVE THE PROBLEM BY EXERCISING THE PC MUSCLE ( The pubococcygeus muscle), IS THE MUSCLE BETWEEN YOUR PENIS AND YOUR ASS. PLEASE CHECK THIS ON THE INTERNET (http://www.wikihow.com/Do-PC-Muscle-Exercises) , AND YOUR SEX PROBLEMS WILL BE SOLVED, BE STRONG AND PATIENCE,GOOD LUCK!

  12. Many of these problems can be self induced mentally. For the amount of people that take accutane annually, these problems highlighted are few and far between. Maybe your issues are connected, maybe they are not. There is always a risk taking prescription medications, and one must weigh the potential negatives with positives.

    In the study done by Sanchez and Dorantes, there is no conclusive affirmation of sexual dysfunction. They found 6 people…yes 6, that reported having sexual dysfunction in conjunction with symptoms of depression. Their symptoms of depression are likely linked with their sexual dysfunction. What was the sample size where they picked the 6 people from? The sample was 20 people, hardly a study to hang your hat on. Correlation is not causation, and in the abstract of the study the researchers suggest further research is warranted.

    Do not fall prey to people peddling misinformation and hysteria to push you towards their products. “Has this study been ignored by those whose job it is to protect or at least inform the public of such a deleterious effect of this prescription drug?” No, the study has not been cited as it only highlights further areas of research. The author ends on this open ended question pointing to some conspiracy. There is even debate within medical journals on the cause of depression in accutane users. Questions arise to the causation, is it because of the initial breakout and side effects? Does it negatively cause issues within the brain? It is still being debated.

    I highly doubt the researchers on the rxist team had any say in this article. As scientists, they would know that this article is nothing more than a simplistic look at correlation between accutane use and sexual dysfunction. Makes this entire website look like a sham. Makes me question the oversight by these “medical professionals.”

    • Sanchez and Durantes absolutely did not surmise that erectile dysfunction was secondary to depression, but that both were plausibly linked to Accutane’s unintended effects on the central nervous system.

      The study included a control group being treated with an antibiotic.

      …All of the patients had acne!

      …but the rate of erectile dysfunction was “extremely” higher in the group taking Isotretinoin. Patients were also pre-screened for depression, erectile dysfunction, and testosterone or DHEA outside of normal bounds and they were excluded before the study began. Not a study to “hang your hat on”, but certainly a red flag.

      This article was also never intended to be conclusive scientific evidence, but patient narratives and correlative studies. The product being sold here is a cautious approach toward a controversially dangerous acne medication.

      Attacking another’s professional integrity based on misconceptions is a bit harsh.

  13. How does one weigh the risks of taking accutane when sides like sexual dysfunction are not even listed as a possible side effect. Pet scans on the brain of accutane patients have shown massive changes in brain activity. Accutane has been shown to significantly reduce dht synthesis in the skin by 80%. If you think serious changes like this cant effect someone’s mood and sexual performance then it’s you falling prey to misinformation.
    However I don’t need studies or bullsh*t docs telling me what accutane has done to my body, I lived it first hand and never been the same since.

  14. My fiance took accutane for about 8 months. Its about to ruin our relationship. I was with him every step of the way. Trying to support him and help him through every heartbreaking side effect he experienced. He’s been off of accutane for almost 8 months. We’ve had sex once in the past 7 months. The feeling of rejecton that I have is almost unbearable. I haven’t found many support forums for significant others of those who have taken accutane, and no one really understands it when I tell them. I’m so madly in love with my fiance but how do I have a healthy marriage without any intimacy, let alone the mental state I’m in after feeling unwanted for so long? I want to be there to support him thru this and maybe I’m a terrible person for bringing light to what significant others experience. Accutane and all off brands need to be banned. The fact that dermatologists still prescribe it is unbelievable. My heart aches for each and every one of you that have personally gone thru the accutane process. I don’t know what’s it’s like first hand, but I’ve seen the consequences and I know it’s difficult.

    • K,

      Seems we are in similar situations..

      I am a victim to actutane and suffer low libido and dryness regardless of my yearning to be intamite with my boyfriend. I have tried numerous lubes but just want to feel sexy again and enjoy sex with out lube. My boyfriend recently told me something is missing because of our lack of sex, which killed me because its out of my control. He feels I am not attracted to him and wants to feel wanted- know that is not the case with your fiancé- I was just being insecure and avoiding the elephant in the room. I am going to a holistic dr to have my hormones checked and start natural therapy. The best advice my therapist told me is to “get to know each other again”. Intimacy isn’t just sex.. Cuddle more, kiss more, hug more – anything but sex (for now) because his erectile dysfunction can also be mental. Try not to focus on the negatives be positive and work on natural resolutions for now.

      • Samantha,

        Thank you for your message. We have since gone to counseling. Our first weeks homework was to hug 30 seconds a day. With that he became more affectionate, but that last only a week. I’ve been begoing him to make out with me for several months now, but I can’t even get that. I haven’t given up yet, but it is so tough. He’s been on T shots for months now, but those haven’t worked. Its added so much stress to our relationship, but we’re both still hanging in there. Hope you and your boyfriend can too.

        K

        • My 40 y/o (midlife crisis?) husband has been on Accutane probably for close to 8 weeks. We have been together for 6 years, have 2 kids (one is just 3 mos. old). We’ve had our ups and downs throughout, but we got married 6 months ago and it was an event HE set up completely with a special judge at the courthouse, included our 5 y/o son as the ringbearer, and invited his childhood friend and wife to witness. This was not a forced occasion on my part. We’ve since had notable close/huggy/intimate moments and I felt more settled in our relationship than we ever have been (granted, I was still uncomfortable and pregnant during this time). Come early December last year things seemed extra snappy and weird. The hubs is a like-clockwork, staid guy. Noticed he was drinking heavily during the month (4 bottle boxes of wine every 2-3 days, not kidding). Then after the holidays were over he sits down and tells me that we haven’t been getting along for a long while and wants a divorce (!!!!). I still feel totally blindsided and am trying to figure this out. There was no putting me on notice or saying there’s problems, we need to try to fix this, go to therapy, NOTHING. He is as cold as ice and no one can talk any sense to him. So while I initially thought of the classic OTHER WOMAN (especially the fact that he decided to get on Accutane to begin with), these last few weeks since the big D-bomb he has pretty much been home, but still obstinate towards me and this whole situation. He “turned me down” for the first time ever Christmas evening. In December he usually has a fair # of work Christmas parties, but did have some extra nights out (which is why I still sorta entertain other woman, but overall Accu-induced personality change?). But these last few weeks since the D-bomb was dropped on me he has pretty much been home like usual (could still possibly be a potential work honey, who knows?). He says he can’t / doesn’t trust me and just seems overly paranoid (which also could be classic cheating projection). I don’t know, but all of this is behavior is so left field, weird, and incredibly final for no good reason. I initially questioned the Accutane prescription when he started taking it because of negative stuff I remember hearing about suicides in the media in my teens/20’s, but let it roll. Then weeks later, BOOM, divorce time! I am getting ready to move out of our place in a few weeks with the kids and am confused reaching for straws here. I Googled “Accutane affect behavior” and all this mostly negative information comes up. My next place will be a short term lease in our town so that our son can finish out kindergarten. I am preparing to move on, but am wondering if things level off chemically in the body with the Accutane at the end of the treatment period. I am not sure exactly how long he will be on it, but am assuming, worst case, Spring. He truly thinks there is nothing wrong with him or this whole situation he has set forth, so I doubt he will quit the meds cold turkey on my request. His was not a face affliction (only here and there), mainly neck and back acne type stuff, but he’s had problems since he was a teenager. This is all just so odd to me. I can actually accept another woman at this point, but if our family is breaking up over some stupid acne drug, or it’s a combination of one feeding into the other, I guess time will only tell. Am just wondering here if anyone else has gone through something similar.

  15. Hey guys,

    I’m 18 and had tried everything else to clear my acne and didn’t work so did accutane. I am always happy and stuff so depression is and was never a problem. However I have this erectile dysfunction too and don’t know what to do especially im at uni now…did u guys speak to UR dermatologist about it or GP?! I have to make an appointment soon to see what they can do?

    Also anyone who has found stuff that has permanently treated their issue can they put it on here would be nice. Keep the hopeeeee guys :)))))))

    • Dear H

      Accutane can cause sexual dysfunction. This will often clear on stopping. But probably better to stop sooner rather than later. The key issue is whether it endures after you stop. If it does, at the moment, we don’t know of a cure. We’re working on it.

      It would be great if you can file a RxISK report and take that to your dermatologist and see what s/he says. Point them to this post as well. If you have a good doctor and can engage them with this issue in finding a cause for the problem and an answer to it it would be wonderful.

      The more people who recognize the problem and get involved in trying to find an answer the better for all of us. There are likely to be links between this and PSSD and Post-Finasteride syndrome

      DH

      • Doc,

        Can u help me out. I’ve been on it for3 months with 40mg first two months and 70mg on the third month. I have been experiencing this ED since after the first month… What do u think is the best decision for me now to do? Once I went and spoke to one of the dermatologists and he was like it’s not a side effect on the official thing and he’s never come across someone having it and he said it could be psychological. I very much doubt this now…. I’m great state of mind think it’s physical im 18 don’t want to ruin my life just for this treatment. My face hasn’t even cleared up yet. Can you tell me what I should do? I could speak to different demr? More importantly..Shall I stop the treatment?

        THANK YOU

        • Anon

          We don’t offer medical advice. We will give a view about whether a drug has caused a problem or not – and Accutane certainly can cause enduring sexual dysfunction.

          Has it caused this for you – can you fill a RxISK report and take to your doctor – this gives a score to indicate if its possible or likely that it has caused it. Give the RxISK report to your doctor. If you have a doctor who listens this is the best way forward. Either way can you report back – we are keen to hear about doctors who listen and doctors who don’t.

          Best of luck

          RxISK

  16. Hi everyone

    I’m an 18 year old student who’s been suffering the curse of acne for the last 5 years . I have tried every single thing , you name it . I was so tired of everything not working and my face just kept getting worse . Extremely red blemishes and large pimples it was to much for me to handle . So I was prescribed to go on Roaccutane last September but due to my exams coming up I started taking them the first week of December 2014 . Before taking it , my libido was on point . Never had an issue with getting an erection , now I feel like my body is an old man I can even get the normal morning wood my sexual activity as drop drastically and it’s so bad . I only been on it for two month and saw it and consulted my Dermatologist and now I have stopped all treatment . Praying that I’ll get my body back

    • Mate I’m in a similar situation to you.. Nearly exactly the same. I’ve been on it for 3 months now shall I wait one more month as I have my appointment or go consult them now and stop it coz iheard it ain’t good to stop in the middle of treatment?

  17. I’m 25 now. When I was 19 I took Claravis for 6 months. Since then it’s been a never ending battle with lack of sex drive and not being able to get/keep errections long at all. I wish there was more focus on this like the ipledge crap for birth defects. I’ve tried everything except ED pills. Just wondering if we can file a lawsuit or if it’s frivilous?

  18. I took accutane for 6 months at the age of 15. I am 34 today and had ED and loss of libido ever since I took Accutane and that is 19 years ago! I am fully healthy, well trained and all possible physical tests are normal, a bit low testosterone but still “normal”. Hope there will be some solution in the near future to reverse the side effects.

  19. I’ve been on Clarivis for about 8 years on and off. I started in my early 30’s and am now 39. I’ve never had nodular or cystic acne, but what I did have was an extremely oily complexion that traveled down my neck. To a lot of you this will sound excessive to take such a drastic and controversial drug. To me this was just as crippling as the acne so many suffer from.I knew some of the risks associated with Accutane and had many friends/family who had been on it at one time. Oddly enough I still view it as the miracle pill, it not only cleared my face but it’s like the fountain of youth, but with anything so amazing there’s another side.
    I was only prescribed 10mg 2x daily, but after a few weeks I realized 1pill was sufficient and I had no side effects, and a back stock to keep me going, it was amazing! I’ve voluntarily been on 4 different 5mo. rounds of treatments over the lat 8 years and to date have about 15 pills remaining.
    Additional I also suffer from OCD, cleaning issues specifically. I sought treatment last year and was started on Prozac. Because apparently the chemical imbalance you have from this is treated with anti-depressents. I was actually more apprehensive to take Prozac because of lack of sex drive and ongoing tiredness associated with the med. The birth defects and depression side effects never worried me with Claravis.
    I noticed a significant decrease in sexual libido, and female dryness over the past 2 years. None of which had been an issue previously. After reading many different stories, articles, and literature about Accutane products I am leaning more toward the fact that this very well may be of my own doing by taking Clarivis. I’m not saying there can’t be other factors,but this has been with me for 8 years and Prozac was only for about 7 mo. I thought after stopping things would improve, but it’s been a full year since I’ve taken Prozac and I’ve only had maybe 4 Clarvis pills in that same time.
    I’m looking for any advice female patients may have, moving forward. I’m uninterested in judgement, or looking back. I remain positive and focused on making the most out of my sexual future however I can. If you have any suggestion/ advice it would be greatly appreciated. Specifically what type of doctor you may have consulted first, PCP, or Gyn.

  20. I am 48 and took Accutane when I was 19 for a few years. About 10 years ago I noticed a lack of libido. I could not reach orgasm while masturbating. I then noticed when I had sex with a woman that I had ZERO feeling in my penis. I could not tell I was inside. At first I thought it was the girl until after a few other partners I realized I had the same results. I saw 5 different doctors and no one had a clue as to why I was having this issue. My testosterone levels were low so I take Fortesta and use Viagra. Nothing helps and now I don’t date or even enjoy life. It really is horrible. I came upon this thread while researching.

  21. I am in the same boat as all of you and have been searching for over 10 years how to reverse the lifelong effects of this poison. I was given 3 cycles from ages 15-20. Overall skin is worse, prematurely aged me and ruined my body and life. Something needs to be done I’m tired of waiting for a cure that will most likely never come. Action needs to be taken against the company and doctors who give this poison to kids who just want clear skin and have no idea that it is going to rob them of their lives.

  22. Im a person who took roaccuatane and I never linked severe abdominable pain to this drug. I was young naive and took it because of my skin doctor said so. I didn’t have anything happen while i was on the drug and i made sure my dry skin was covered so a not to get cancer. I started to get massive painful cramps in my stomach when i was in my late 20’s which lasted into my late 30’s and are now thankfully gone. I also got a racing heart condition which to this day is undiagnosed. My stomach pains were undiagnosed and i was also referred to a pysychiatrist as well. My family have thought i was mad most of my life since this drug also. I also get random sexual disfunction not always just sometimes which is annoying. I have also always been passed over for promotion in my job all the time since roaccuatane.

  23. hi,
    i just read the entire blog. i had taken this isotroin two years back. within two weeks i felt my sex desire going down. i stopped immediately. i m fine now. there is a remedy to come out of ED. it is a home remedy and traditionally followed in india. follow this: take handful of drumstic tree leaves and its flowers. clean it. then, along with this add small size onion chopped, then pepper(powered, less quantity, just for good taste). boiled them with water (half litter). all essence would have extracted. just have this juice everyday in the morning or evening. you can take this as many times as you want per day.

    secondly, to purify your blood from all sorts of filthy medicine stuff, take fenugreek (20gram) soak it in water for 3 hours and have it with that water(would be bitter little bear it). you can take this twice a day.

    within two weeks you will get erected when you see just chicks. you need not spend more money for drumstick leaves. 0.0% side effect. good for health to build immunity too.

    there is a way for everything. dont worry. this will definitely work. at least you can give a try for no cost.

    cheers

    • I just used accutane for a week and have already stopped using it for a week up until now…I am able to get erection but it won’t last long as normal and its hard for me to get hard…I’m still try to find way to fix it….I went to doctor and he wanted me to wait a week more to get a medicine and picture for him to analyze more….I also went to other doctor and he said probably im depressed without realizing it…however I also depressed after using it

  24. I took accutane at ages 15, 17, and 20. I’m 30 now and look 16 but feel 60. Every side effect you can basically list I have. Stunted growth extremely dry skin, joint pain, eczema, foggy brain, no muscle, attitude change no motivation, cant gain any weight, sexual dysfunction, hairloss etc.. i also noticed something wasnt right compared to my peers. Doctors and everyone else telling me there is nothing wrong and to just be patient. Well I got educated from research many years ago praying that something would cure us. Seems like this drug destroys cells along with your body with life long lasting side effects. I have taken every supplement and other plans of actions to help without avail. If the doctor had told me this was designed as chemo drug and the side effects would be with you for the rest of our lives, then no way would i have taken it. Both doctors and roche are to blame for ever giving this to a kid who hasnt developed. They should have to use the billions a year they made off it to research a way to reverse it, if even possible. Everyday above ground is still a blessing an many others have it worse, but you cant help but think how different your life might have been had you made better decisions in your younger years and that hurts every time. Much greater awareness needs to be raised.

  25. Hi
    I took roacutane while i was 19. Before then i was normal in every way. Since then i have had many serious gay thoughts. I have slept with many men as their girl. I have been bedded by many gay top men for just casual sex. I attribute this fascinatin with roacutane. I have never been cured and still sleep with men so they can have sex with me all the time. i am a gay bottom after roacutane. i have been gayed and screwed lots by men.

  26. I took Roacutane after i had many other prescriptions that didnt work well. It dried my skin and made me feel lethargic. My doctor said that was normal and would stop after a while at the end of the course of this treatment. Around 6 months after the treatment I noticed i wouldnt always get an erection. It was on and off and sometimes went small during the intercourse. My doctors could find nothing to indicate a problem so i have lived with it ever since. Sometimes i cant and other times its very good. My normal actions are gone and replaced with irrational physical goings on. There is no cure. Dont take roacutane guys you will regret it.

  27. I was given this drug in 2010 for a few pimples. During the course I experienced low libido, genital numbness, joint and muscle pain, and dry lips. Five years later, all of these symptoms have worsened in addition to other symptoms that began one month after stopping treatment including digestive problems, dry and thin skin, dry hair, hair loss, tinnitus, muscle spasms, hand and feet numbness, chronic fatigue, memory loss, and an overall feeling of not being well. Dermatologists need to be informed and not hand this stuff out like candy for mild to moderate acne. If they do, they need to warn the patients about the possible permanent side effects. I was told that none of the side effects were permanent, except if I became pregnant, there would be possible permanent damage to the fetus and I would have to get an abortion. The permanent side effects are definitely not worth the risk.

  28. Hello, I am a 20 year old male from the United Kingdom. In 2014, I decided to give roaccutane a try for my treatment-resistant acne. The acne was not cystic, but it did not respond to antibiotics. Before seeing a dermatologist, I did a lot of research into roaccutane and decided that the benefits outweighed the risks. Little did I know, I was about to make a very big mistake. As a precaution, I only took roaccutane for a short amount Of time (1 month course-40mg per day). By taking it for a short amount of time, I thought I would be avoiding long term side effects. How wrong was I.
    Towards the 4th week of my course, I started to notice I was depressed, and my sex drive was greatly diminished, and found it difficult to achieve an erection (even with a hot girl). I thought these effects would be temporary, but I stopped taking it just in case. And to my absolute horror, the side effects persisted. My penis when flaccid has reduced in size, and has a “shrivelled” appearance. However when I do eventually get an erection, I find it difficult to reach orgasm. I have also noticed a decrease in my ejaculatory volume. At the young age of 20, I feel like I can’t go much longer living like this. Having depression is one thing, but having a dick that hardly works is just ridiculous. It’s been 9 months since I took roaccutane, and I have to say, my life hasnt been the same since.
    To combat these effects, I have tried a combination of supplements and have had some improvement. But by no means a “cure”.

    -5HTP
    -vitamin b6
    -niacin
    -magnesium
    -Horney goat weed
    -L-arginine

    If anybody would like to talk about this issue, I would be happy to do so. You can email me: henthornedward@yahoo.co.uk.

    Some days, I have been very close to ending all this bullshit. but the reason I am still here is because I love my family, I don’t want to put them through that. But I honestly don’t think I can continue much longer like this. For the past 9 months, I have literally been hanging on by a thread. The amount of misery this drug has caused me is hard to put into words, but hopefully together we will find some way to get through this.

    • Hi Ed. There is a thread on acne org called “Repairing Long Term Damage From Accutane”. Until post-Accutane sufferers have a proper forum, this seems the best place to gather to discuss finding ways out of this.

  29. I only took roaccutane (isotretinoin) for 1 month. does anyone know if this depression/sexual dysfunction is permanent? it’s been 9 months since I took it and there has been little improvement. I took it for such a short amount of time so I’m hoping this will all go away given enough time.

  30. This is complete hyperbole.

    No one would usually bother to read the journal references the author included, and so they add an air of legitimacy to the article that is not contrived. If you do bother to read the supplied articles, you will see that there are two cases of sexual dysfunction associated with Accutane among females reported, and a few more cases of erectile dysfunction. The odds are overwhelming that these effects have nothing to do with Accutane, given that sexual dysfunction affects a huge subset of the population (minus medication). These numbers are so minuscule, and the results have not been replicated properly, and this drug has been on the market for some time now.

    All large-scale, blinded, and/or well-designed studies show that Accutane is highly safe with the exception of its teratogenic (birth defect) effects, something that only occurs in patients who are not responsible or who are not educated (i.e. do not take the necessary precautions to ensure that a pregnancy does not happen while on Accutane).

    There are more risks in taking long-term minocycline (antibiotic) than Accutane, which most GPs have no problem prescribing to teenagers and young adults for mild acne (and virtually no one criticizes GPs for this).

    In sum, sensationalism is fueling the media reports on Accutane rather than evidence-based science. Even some GPs are fooled my the nonsense that is heralded in innumerable media stories––either that, or they are afraid of law-suits based on a few testimonial reports rather than real data.

    • This response sounds very like Formerly 98, John Alan Tucker. Formerly 98 is mentioned in several earlier posts about PSSD where he was involved in removing the Wikipedia PSSD page. He has also edited out of existence almost any reference on Wikipedia to the side effects of drugs like the Fluoroquinolones and Olanzapine.

      While there is an appeal here to science and controlled trials, the likely driver in Formerly 98s case and perhaps jdlkm1234abc may be something much more anecdotal – perhaps a sexual difficulty at some point earlier in life – from which a conclusion has been drawn that all that is involved with SSRIs, Finasteride, or Accutane is what happened to him. Anyone can have sexual difficuties – this is true. But these difficulties are rarely accompanied by profound genital anesthesia – whereas SSRIs for instance produce very clearly and demonstrate genital anesthesia within 30 minutes of having one and this provides the basis for their marketing authorisation for premature ejaculation. Accutane is also a serotonin reuptake inhibitor

      David Healy – aka 666 or jdklm123456789abc

    • To assume that trials always pick up on every side effect a drug has, is incorrect. I can personally assure you, that this drug causes sexual dysfunction. You only need to look at other 5 alpha reductase inhibitors such as Finasteride. Studies on this drug clearly demonstrate that it can have lasting effects on users, it has been shown to effect protein expression in the Nucleus Accumbens, an area highly involved in pleasure. Now if this drug which works as a 5 alpha reductase inhibitor can do this, its not too hard to believe that its plausible, that Accutane, a known potent 5 alpha reductase inhibitor can have similar effects.

      Sexual Dysfunction is common, this is true, but sexual dysfunction lasting years is not. I have experienced sexual dysfunction for the last 10 years. Trust me that, persistent sexual dysfunction is different to sexual dysfunction. No amount of sex therapy is going to fix this. But I implore you to give this medication to your teenage son and daughter, and we can see if after 6 months, you still hold the same viewpoint.

  31. Hi I’m a 37 year old married female. Went on Roaccutane over 20 years ago for about a year. I was completely normal one minute and not the next-major extreme in difference. Normal libido and orgasmic before the drug to low libido and never orgasming again. I thought something seriously got damaged with my privates or something. Every doctor i went to said its all in your head blah blah blah but i knew it was total rubbish. Its only the last year from watching a tv program about others having the same symptoms that the lightbulb totally went off that it was the drug that did this to me as the timeline from when it started happening is smack on. I’ve learnt to live with it but i feel like myself and my husband have been robbed. I would love a cure. Only people that have this understand. The people that say there is no proof that this drug did this would think differently if it happened to them. It seriously does something wack with your nerves and brain that they haven’t pinpointed just yet but trust me it DOES!

  32. Antecedent:
    I was only 18 when I have become it: I had a beautiful girlfriend, I was very happy -my libido–oh my God…! it was so high that I need to ask God to reduce it in a way….SO!
    After Roaccutane:
    But I had very-very acute Acne conglobata…. I became Roaccutane two times, 2 courses – this was terrible, my father – I remember, asked me – what is this?- I had bloody hematomes on my lips, and I tried to set him to ease, this all is a treatment…don’t worry!
    My libido:
    After the second time I become Roaccutane- I fell to the other side of the horse..dramatically. My girlfried had done with me…!!! It was off!

    Therefore you kindly readers –> Be care with Roaccutane! This is not only a Vit-A version.

    Just wait and see!

    How can it rebuild/reset the sexual life after Roaccutane? Forgetting viagra and ciallis, others?

  33. Not to make light of the matter, but doesn’t having bad skin (i.e. acne vulgaris) also kills your sex life?

    Take accutane, clears skins, but kills your sex life.
    Not to take accutane, grotesque skin, puts people off, also kills your sex life.

    To take or not to take, that is the question.

  34. 27 took Accutane when 16 for about a year. Told no permanent side-effects. Was healthy and extremely energetic prior to Accutane. Family has no medical issues too.

    Once I started Accutane I got:
    Depression
    face dryness
    Facial coldsores or the like
    lack of libido
    nose bleeds

    After the treatment within one year I developed (and have to this day decades later);
    sebhoric dermatitis
    dry eyes
    dry skin
    eyebrow hairloss
    head hair loss
    continued nose bleeds
    joint pain leading to injuries
    back pain requiring chiropractor (asked if I had been in a car accident after seeing x rays)
    blushing
    anxiety
    more depression
    Erectile dysfunction (soft even when erect)
    extreme brain fog / can’t concentrate
    short-term memory is real bad

    I was only young at the time. Now I think to myself this: how can the drug permanently get rid of the acne without permanent side-effects?

    You are in a small concrete room with only one opening. In this opening your food, oxygen and many other things you need appear. You are very happy aside from the fact that mosquitos also enter from this opening. They bite you every night…all night. You use the telephone next to the opening to call for help on this matter one day. the operator says he has fixed this issue with many other people and it is as simple as constructing a brick wall to block the opening. he says you will experience temporary shortness of oxygen, food and other benefits but after the wall is constructed they will all come back to their normal rate. He provides you with the bricks, which he places in the opening, one brick per day as well as temporary air cylinders and food packages. After some time the wall is nearly up and you are happy the mosquitos have dwindled in number. You place the final brick and the mosquitos stop. You are extremely happy and are now just waiting for the oxygen, food and other benefits to return. Then it hits you like A BRICK IN THE FACE…how could I have been so stupid… the mosquitos came in the same opening that all those other things did…what have I done. You gasp for air as you start banging on the wall in an attempt to break it but your hands are too soft… You call the operator and ask for a hammer but he says the opening is now closed and he does not know how to send one to you. You tell him you are finding it hard to breathe and the air cylinders aren’t good enough and he says it is all in your head and that you should be glad the mosquitos are gone.

    What is abundantly clear to me now is that my acne has never come back which means these side-effects will never go away either. I would actually be HAPPY to see my acne come back.

    Some successes I have had (no permanent relief just temporary bandaid solutions);
    Burning the veins within the nose to reduce nose bleeds (not allowing them to dry out).
    Taking Viagra has helped increase the strength of erection slightly…enough to allow for penetration.
    Gently rubbing of 1% pyrythion zinc into eyebrows with tooth brush to clear sebbhoric dermatitis
    Eating less sugars and fats
    Moderate weights and cardio (if I overdo it I injure myself).

    I would like to say for all those people who say this is all in our heads. Maybe one or two of the symptoms might not be related but to go from a perfectly healthy person to a person with over 25 ailments in the space of one year is not normal. To go from being able to memorise complete essays word for word to not being able to remember where I put the keys 5 mins ago, all the time, is not normal. One day I hope that the company will be made to pay… I am sure if we all get together we could make a class law suit… thousands of people with similar permanent side-effects (which were supposed to be temporary) is too much to brush off as coincidence. if the maker of Roche thinks otherwise than I would ask him to feed himself or his kids this poison to lay the issue to rest once and for all.. if he believes all the side-effects are only temporary he should have no issue with this.

    Finally on a note of hope. Even with all this side-effects I am still trying to move on with my life. I exercise whenever I can as that improves my mood (and my body). I keep thinking how other healthy people have it much worse and are being killed every day and starve to death. The Viagra also helps. It is not a complete fix but even that small amount that it helps gives me some happiness. For those others out there who are finding it hard to cope just keep remembering that there is always someone else who has it worse off than you and has the courage to continue. Find hobbies and things that interest you and pursue those. I have learnt not to care about what other people think and to do things which make me happy. I have pressure at home because I struggle at university (due to the side-effects. Mainly anxiety). My family only wants the best for me but they don’t understand that I am incapable of certain things now, and having all these side-effects (many of which they are unaware off) has really put things in perspective. They want me to get married have children and get a good job ( my family is well-off and hard-working but I feel place too much emphasis on money and looks). I don’t have time for this I just want to enjoy the limited time I have left. Once I finish, if it is in gods will, I will be moving overseas, possibly to China, to live a life how I want to. I will find a modest job and just enjoy every day doing what I want to when I want to. I will stay in contact with my family but i will live my life how I want by making money to live not living to make money. I am gratefull my joint pains and back pains have been slowly improving with exercise.I anticipate my body should hold up relatively well until I am at least 50. This gives me over 20 years to enjoy myself, meet new people and just live. If I meet a women who understands me and loves me for me then maybe i will find love. I should also note that I am gratefull for the 16 years of life which I thoroughly enjoyed and lived to the fullest prior to Accutane. Good luck to everyone, keep your chins up and just plodding along..we are all in this together.

  35. I was on Accutane at 16 years. Now I’m 22 years old, and still have the same sides. Erectile dysfunction and hormonal Problems the worst of all. Another Problem of us is the ignorance of the doctors, they say its in your head (Fucking bullshit). I can only say, do not take this drug, its dangerous and the sides can be permanent (I never give up and fight on myself) Don’t go to doctors anymore.

    • The doctors and drug companies are working together. I was given this drug in 1986 when it first came out at that time they knew it caused sterility in male dogs but told no one, now at 40 my testosterone levels should be around 650 to 725 instead its 228 and I am completely sterile after many genetic tests no genetic cause for this was found, no one in my family on either side back four generations had any of these problems. Clear skin was not worth losing the ability to someday be a father!

  36. Well, I never thought I’d ever share it, but yeah.

    Accutane destroyed my sex drive.
    It’s not that I can’t get hard or anything, it’s just that.. When I start fucking my girlfriend, I don’t last long at all. I can barely ever get her to come and it’s pretty hard on my self esteem.

    Regardless, I’m not going to die from this, I’ve been through worse.
    However, I completely recommend AVOIDING ACCUTANE AT ALL COST.

    You’d rather have problems with sex than having acne?
    That’s the worse mistake you can ever make.
    That’s.. The worse mistake I ever made.

    My acne did go away – not completely, but it did prove to be very efficient after a little over than 6 months.
    Regardless, it was not worth it.

    If the only reason you want to get rid of acne is to get a girlfriend or a boyfriend, then you’re an idiot.
    Your acne will go with time, and a girlfriend/boyfriend that loves you for what you LOOK like will also go with time.

    Your partner is one that will love you for who you are.

    The decision is yours to make, sure, but at least mark my words, and let them have an influence on your choice.

  37. I took acutane through most of high school, and I’m 20 now. I stopped and haven’t taken any acne medication (topical only) of any kind and I still feel like my erections aren’t as strong and long lasting as they should be, I can never stay hard for more than 5-10 minutes with my girlfriend before just losing it completely. Doctors told me I was too young for ED, and I ordered some samples of Viagra from a Canadian pharmacy: http://goo.gl/zRSgN2 Now, I can just take a tiny dose, like 1/4-1/2 of a pill, and be ready to go completely in a few minutes. Just using it a few times helped me get my confidence back, and I don’t really use it often anymore, just super helpful in getting over it initially. Anyone else ever order viagra or any erection drugs online with any good results?

    • Thomas, I would try herbal supplements, L-Arginine and Niacin to help improve blood flow. The urologist I went to gave me a Viagra prescription through this website because it was cheaper: https://www.healthwarehouse.com/

      But they do require a prescription so it is legitimate and safe. If you really want Viagra I would explain your situation to a doctor, write down your side effects if necessary or print out a study, and they should be able to give this to you. It’s cheaper through the site I listed.

    • ahiio, It’s obviously up to you but I would stop because I do not think the risks are worth it for your health just for something cosmetic. I have post finasteride syndrome (ongoing side effects from taking the hair loss drug propecia) since 2007 and it has been life changing, physically, sexually, cognitively. It isn’t worth taking a medication that may alter your hormones. Your physical, sexual, mentla health should come first before clear skin or a full head of hair. These medications affect everyone differently, but the potential they have to change your body is scary and not in the marketing campaigns.

  38. i take these medecine not accutane but isotretinoin. im so worried now. my erection much low . and my desires low . what should i do now plz plz plz plz plz telll me

  39. hi, i have found it very helpful reading these comments on people experiences in helping me deal with how i believe accutane still effects my life. I was prescribed accutane a number of years ago as i had very bad acne and I had a lot of the problems peoples have described here. I am now going to celebrate my 40th birthday this March so it was a while ago. I was prescribed accutane twice the first time i was on it for several months and it nearly ruined my relationship but I had a understanding girlfriend and i am glad to say we have been married for nearly 6 years. The second time i was prescribed accutane I stopped taking it after two weeks. I have been diagnosed with bowel disease, suffer depression, impotence and have been unable conceive children, losing my hair and ruined my relationship with my brother and sister. The worst thing is that my acne was a side effect of another condition i have. It appears that the dermatologist was treating the symptoms and not the cause of my acne. Please note my next comment do not apply to everyone and so should not be taken literally as these are my experiences from my journey. I stopped taking accutane after two weeks of my second dose as I was diagnosed with acromegaly which is a hormonal condition after i had a operation to help resolve my acromegaly my acne cleared up overnight. I now live an acne free life but have to live with, in my opinion the side effects of accutane of which i should never have been prescribed in the first place. I have a beautiful loving wife and continue to try to build my relationships with both my brother and sister, My acromegaly is an on going problem but i am one of the lucky ones even with the problems i continue to live with.

  40. ———- Forwarded message ———-
    From: Dubya B
    Date: 29 January 2016 at 20:12
    Subject: Sad News Regarding David Chow of the Roaccutane Action Group
    To:

    David Chow, administrator of RAG-forum and chairman of the U.K. Roaccutane Action Group, committed suicide last month after 21 long years of suffering severe depression and painful physical complications brought about by Accutane.

    Coroner asks for review of acne drug Roaccutane after photographer’s suicide
    http://www.eadt.co.uk/news/coroner_asks_for_review_of_acne_drug_roaccutane_after_photographer_s_suicide_1_4337597

    I never knew him personally, but Mr. Chow contributed a great deal to those of us left with long-term side effects from Accutane.

    He will be missed.

    • Came on to this section due to a story in today’s paper. Very sad to read the forwarded message.
      In today’s Daily Post (UK – North Wales) there’s a full page report about a young girl who was on Roaccutane. Her dose was repeatedly increased to 70mg which caused her to lose 92% of her pancreas.
      On her discharge sheet, a consultant from The Royal Liverpool University Hospital states that necrotising pancreatitis was ” likely to be secondary to Roaccutane” and stipulates that the medication was stopped.
      What did Roche have to say about this case? – the usual “in the case of Roaccutane, the regulators agree that its clinical benefits outweigh the risks”. Hard to believe that when I see how many comments have been received here and the severity of their cases.

  41. Yes! I’m 31. I’ve also suffered from acutane. Ruined my sex life. I have to use plenty lub. It’s been also 6months sense I’ve taking it. Hopefully it subsides. This is the worst ever. Acne gone but sex life gone. I pray my life comes back together again.

  42. I have been taking accutane for 4 months, Ive started to noticed I haven’t been as wet as I usually am and am worried that it could be permanent damage after reading all this, I’m on 30mg a day, should I just stop taking it all at once or gradually go off?

  43. I took Accutane 22 years ago. My first attempt at intercourse was 3 weeks into it, and it was a failure that left me without confidence which I have never recovered from. I have suffered greatly mentally, with no confidence in my sexual ability. That being said, here are some things that give me hope:

    1) I have had successful sex in the past without ED meds. If I take Viagra, and continue to have sex daily, I can go for several days without the need for another pill.
    2) I have always responded to masturbation and porn. (I try to avoid both now as I suspect they might be the source of my issues) This makes me suspect that my issues may stem from a sort of masturbation addiction/conditioning.
    3) I have a close family member who took it with no issues.

    Trying to be positive, I have a possible theory: It may be that I overindulged in masturbation as a teen, and people who do that may be prone to have acne. This would explain a correlation between Accutane use and libido/ED problems.

    On the negative side: If Accutane damaged something in me, what could it possibly be?

    Also, being almost 40 years old, I have no idea what to expect as far as functioning is concerned.

  44. I’m a 19 year old male (17-18 when I took the drug) who took a six month course of accutane from late November 2014 to late May 2015. I noticed while on the treatment that I was not as horny as I had been. I would see girls that I had previously found super attractive and noticed I was not having as strong of a mental response to seeing them. I brushed it off, thinking I was just going through a phase, I didn’t think it could have had anything to do with accutane, in fact I did not even know at the time that any drugs could affect libido. I thought my sex drive was an unbreakable constant in my life and that losing it was something that only happened to old guys with low t. Today’s date is March 18, 2016, and my sex drive has not come back at all. I have almost zero sexual interest, I want to want to have sex, if that makes any sense. If I see a girl or an image of a girl that would have in the past mentally aroused me, I feel absolutely nothing. I might as well be looking at a rock or a tree. With the libido and arousal problems I also have pretty bad erectile dysfunction. I am able to have sex, however I fail to get an erection/maintain it about half the time and have an extremely hard time getting aroused in the first place. Luckily orgasms are still pleasurable to a decent degree for me. I can masturbate, however I also suffer from the same difficulties with this as with sex. All of my hormones were fine when I had them checked (prolactin, thyroid, testostorone was 768 ng/dL), and there’s nothing physically wrong with my penis or testicles. Recently I was approached by a kid on my floor at college who tells me he has the exact same problems. He took accutane longer than me and at a higher dose, and his problems are more severe. He takes cialis to be able to have sex with his girlfriend, he can’t otherwise and even that doesn’t help most of the time. He has no libido and says its almost impossible for him to masturbate to completion. I never had sex before taking this drug, if you are reading this and are considering taking this drug, I would highly suggest that you reconsider because it may be the worst decision you have ever made in your life. My dysfunction is the first thing on my mind when I wake up and the last on my mind when I go to sleep. Acne isn’t fun (tbh mine was not even that bad yet my derm still gave tane to me like candy and told me it was safe), but sexual dysfunction is absolute hell. Acne won’t keep you from finding love or getting laid, and usually the person who’s hardest on you about it is yourself. Other people never cared about my acne and girls even told me it wasn’t that bad and that I shouldn’t care about it. I didn’t listen, I was self-conscious and obsessed with my acne, and in a perfectly vulnerable situation to take drastic measures that could and did harm me. My advice, stop caring about your skin and learn to love yourself for who you are. Taking this drug was absolutely the worst decision I have ever made, and I’ve become resigned to the fact that I will probably be in this hell for the rest of my life.

  45. I am a physician and took isotretinion for about two months, about two years ago. I had loss of libidos and impotence about five weeks after starting it. This is an unreported side effect that even the dermatologists don’t know about. My advice to anyone thinking about taking the drug is don’t risk it. I have been digging deep into research papers to figure out what the if anything can help it. It seems that this drug reduces the ability of the body to convert testosterone into dihydrotestosterone (DHT). DHT is the hormone that is deficient in men and women and needs to be replaced to get back your libido and improve depression. While taking testosterone will help, taking androgenic steroids such as mesterolone (which is analog o DHT) will make you feel almost back up your old self. Ideally, taking 200 mg of testosterone and 100 mg of Mesterolone (commonly known as Masteron) subcutaneously will help significantly. Women have to be more careful about the dose as they will have irreversible masculinization if the dose is too high. I would say 20 mg of testosterone and 10-20 mg of Masteron per week is a typical dose for women. In Europe DHT cream is available with a prescription and should greatly improve symptoms but it’s not available in the US so you’ll have to find less legal ways to obtain it online.

    • I have taken roaccutaine about 8 years ago for acne ever since I have been on and of depressed and have no sex drive and find it very difficult to get erections . What can I do to fix my future ? Please help

    • Hi Dr. K,

      I too took accutane about ten years ago now and am suffering the long-term side effects. I have some sexual issues, but my main complaint has to do with cognitive and physical deficits. Did you experience any decline in cognition while on or after this medication?

      I am a medical student, and too have been reading research papers and such trying to figure out what is going on with me. I was thinking about trying testosterone with a focus on increasing DHT. Many of my physical symptoms are signs of low DHT – super dry, sensitive skin, lack of facial hair, young appearance, etc. – which makes sense since I took this drug when I was 18.

      About the protocol you suggest: I saw a paper that shows isotretinoin decreases the number of androgen receptors. Are you suggesting exogenous testosterone to upregulate these receptors, and mesterolone to increase DHT which has a strong affinity for these ARs?

      I am interested in how this worked out for you, as well as if you think it will help me. If you want to, email me so we can discuss further.
      jeffscott357@gmail.com

      Best,
      Jeff Scott

  46. I took accutane just before turning 17. I took it for two or three months. It did wonders to stop my acne. I know many people complain about sexual side effects. This is probably due to a lowering of sex hormones. But I was wondering if it also stopped my penis and testicle growth. See if it lowers testosterone levels, IGF 1 levels and reduces DHT during the end of puberty this must not be good for testicle and penis growth. Also I want to know if it reduced my adult height. I did some research and when I was 13 yrs 8 months old (June 1989) I was around 5foot two. A normal growth would indicate that I should have been around 5foot nine. I only grew to five foot seven. Also is there any cure now; and is there a way to sue the drug manufacturer?

    • I was prescribed Accutane back in ’82. I had serious acne so my doc gave me this wonder drug that just came out on the market. I was not quite 18yrs old and of course agreed to try it. At that point i wouldve tried anything to get rid ofmy acne. Shortly after taking accutane my face cleared up, my docs office was full of other docs wanting to see how amazing the guinea pigs face cleared up! Lol
      Within a few months i was losing hair, was almost completely impotent, had virtually no feeling in my genitals and began to withdraw from friends, family and girls especially…..due to embarassement of not being able to get it up! Of course i became depressed, was labelled with schizophrenia……and to top it off my family has a history of Anxiety……i didnt have a fighting chance.
      Thankfully i met an understanding Woman in my early 20’s and things slowly improved sexually. I am 52 now and with the help of viagara of course …i am able to enjoy sex, which was always hit and miss. Oh i forgot to mention i have had bouts with a swollen prostate which has given me problems since taking the wonder drug! Im so used to the side effects now…theyre just a part of life! This drug shouldve been outlawed 30yrs ago…..all i can say is Do Not Allow your loved ones to take this drug! The cure is way worse than the acne for sure!

  47. I am so shocked!!!!!! This explains why I never wanted to have sex or when I did I could never orgasm! Oh my God! I took it for several months when I was a teenager, now I am 47. All my life I was looking for the reason why I was feeling like this and I thought I have psychological problems….and I was raving about this drug how it cleaned up my acne!!!!!! The dermatologist was ready to give it to my son and only due to his final year exams he did not take it yet but would take it next month! Thank you God for bringing this in front of my eyes at the right time. Pray for all of us suffering those life long side effects….

  48. I too have had a significant reduction in desire, stimulation and ability to orgasm, as well as intense pain during penetration sInce taking 2 rounds of accutane 2 years ago. It is ruining my relationships and confidence completely. I am FURIOUS at the company for their leaving out of this information. I am going t try everything to fix it. I want a good sex life and kids in the future. No drug should rob me of that possibility. Who’s up for a class action?

  49. I unfortunately took my teen son to a dermatologist for his acne when he was 14, over 10 years ago. She NEVER EVER me anything about all of these horrible side effects and that this drug is a chemotherapy drug, noone in their right mind would want to give this crap to their children, and especially not for something like acne. So unfortunately I trusted her and my son was on this crap for a few months, and after that developed depression, and was suicidal and aggressive. I never figured out why he had changed so dramatically, while he had never been aggressive in his life, and now he is still the same way and won’t even contact me or his father anymore. I hate that doctor and if I could find her she wouldn’t be around anymore. Furthermore, once he mentioned with me (he is always been shy so this was the only hint I have about his sex life) that his penis was too small. This surprised me at the time (he was 18( especially because genetically it should not be that way (his father had no problems with size). Now, unfortunately too late, I am reading about this. I have no clue about my son’s sex life but he never talks about it or brags about anything, so I believe he might have some problems. I hate that doctor and wish I could find her and give her a lesson she would not forget for the rest of her life!

  50. Thank GOD I’m in no need of this medication but my wife is and she has been rejecting me since she started taking Myorisan (isotretinoin capsules, USP 20mg she does not want to be around me of course not even have sex I’m a man that is only dedicated to the family I don’t go out with friends my family wife and 3 daughters are my life I don’t drink smoke or do drugs I’m a very hard worker and I help a lot around the house and now she has asked me for a divorce I do not know what is happening I have not given her any motives she’s been on this medication for about 2 months and now they started giving her Claravis 40 mg I’ve tried showing her the side effects I saw on the box medicine she’s out of town now and I just saw all this comments on this web should I call her dermatologist and tell her all the symptoms she’s having cause she is also depressed feels worthless and many more things…

  51. Honestly I was already incredibly depressed before taking this medicine, but now, I feel numb, and add to that, impotent. I used to have hopes and dreams and feelings for people, but now, I am a shell who doctors claim “its all in your mind” and dismiss the ways I have been feeling. I am very close to ending this because I will not go through decades more of misery like the last few months

  52. I was already incredibly depressed before this medicine, however then, I had the hope that things would get better. Now that has all been dashed thanks to the crooks at Teca who make Claravis, and I hope to kill myself in the not too distant future

    • Arc,

      Please don’t do that. It may be a long dark tunnel, but there is a light at the end. You can get there!

      Yours Truly,
      a John Doe that cares.

      • Are you sure? because as far as I’m concerned, I just permanently ruined my life and virtually everyone on here who took this poison at one time or another has never recovered no matter what they do. I was already depressed enough before the medicine. Now I can’t even feel any emotions or anything anymore (let alone feel horny), and as far as I’m aware, I’m already a shell. I’m VERY tempted to put an end to this inescapable nightmare especially considering that every doctor I’ve visited just denies there’s a problem like they’re some crook paid off by Hoffman LaRouche.

  53. So do we just die alone and enter the void like this, or is anyone going to actually help. Have I really entered a tunnel from which other individuals HAVE made it all the way through, or am I stuck in a pit watching my existence slowly crumble? I am tempted to find a way to end it all, unless anyone can provide a GRAIN of HOPE to put an end to my crippling anhedonia of all kinds (sexual, emotional,etc). I have already been killed so now shall I cease to exist?

  54. Taking accutane often makes me realize I had easier access to a quick painless means of ending it all. Anyone who even SUGGESTS that I will permanently live like this without getting one hell of a payback (and more than money for sure) is full of crap. Honestly I would love to take down the makers of Accutane by all means possible and make them suffer (Heavily) for their crimes.

  55. We need to find a way to make the drug companies pay in terms that will actually keep them from screwing people over like this. Simply suing them is not enough.

    • i totally understand how you feel it’s very much so depressing but please don’t end your life over this. I know it’s hard because I’ve been going through this a whole year now and still looking for answers. Just pray about it. Everything will be fine. We gotta stay strong for one another. It is away we just haven’t found it yet and i pray that we all get justice. This is very sad situation.

  56. Hi all. My son took Roaccutane about a year ago. He now tells me that he’s gender dysphoric. As far as I know, he never had a problem in his entire life, and now this, out of the blue. He is reclusive, never dates, and now he wants to be a girl. If anyone can help please contact me on pycraftm@worldonline.co.za. Go well.

    • I appreciate that Accutane can have serious side effects, but gender dysphoria is not one of them. He has had a problem, it’s just that he’s only just decided to confide in you about it.

  57. I went on Accutane at the age of 21 and it gave me perfect skin for 20 years. Now, 20 years later I am in incredible health and not only that but look 10 years younger than my age. After taking Accutane I did not have a pimple for 20 years. I can’t believe some of these people on here blaming anything and everything on Accutane it’s ridiculous. It’s a great drug that changes many people’s lives for the better as they face the world with perfect clear skin and get their confidence back

    • Yes! it cleared my skin but it also ruined my sex life. I can’t believe you would think people would take up their great time to just post something that’s not true is baffling. Of course everyone has a different side effects! If nothing at all. You was just one of the lucky ones. Thank God for that instead of judging us. Our lives are damaged enough.

  58. i am also taking this medicines from last 2 year as a acne treatment, but now i am also feeling that i have a problem of Erectile dysfunction. so now plz help me and guide me that what i have to do ????
    plzzzz help somebody from your experience.

  59. RoAccutane killed our beautiful son. Not on its own. But it did all the stuff to him that so many brave sufferers have written on this site. And because he felt so low, he was given the SSRI Seroxat, to alleviate his mood. And the combination of the two meds drove his anxiety through the roof. And he was considered to be temporarily psychotic. He asked to go into hospital cos he couldn’t stop the suicidal thoughts going round and round in his head, he felt he might kill himself. He was 21, at Uni, set for a First Class degree. But the anxiety and the strange fear never left him. He never went back to Uni. He had akathisia from all the meds. No one would listen, no doctor would take on board that his suicidal thoughts were not caused by his (now much improved) acne. He lived another 11 years of hell, never realising that his mental hell was due to the meds, not to him. He created a successful IT business, but in the end, a combination of derogatory remarks about his prowess by a stupid older woman, and callous bullying by a psychiatrist, caused him to leave this world. RoAccutane/isotretinoun began his torture. He wanted us to go on and find a solution. We must all do this. We cannot allow Roche to continue to get away with the fact that they marketed a drug which was for chemotherapy, changed DNA, ruined lives, killed many youngsters, and even the MHRA do not seem to want to understand this. Don’t give up a life for these people, fight for answers, and warn everyone. This drug maybe be seen as a quick fix, but can lead to a living hell. We need investment to find safe, effective and affordable acne treatments, like Blue Light therapy, laser therapy if needed, diet research. Remember, someone in Big Pharma is making big bucks from this RoAccutane/isotrwtinoin and they don’t give a fig what it’s doing to you.

  60. I am 43, female, and took Acutane when I was 18 for about 6 months. I often wonder why I absolutely cannot have an orgasm and I am very sispicious that it is because of my Acutane treatment. Really, I have tried and tried with different partners with no success. It really sucks to not even know what these awesome things called orgasms are! The very reason for having different partners is because I can’t keep a man around. I even became a single mother and it is not confirmed that that is why but I am almost positive it has a lot to do with why he even left me. Feels so sad. Honestly, I think that the partners I had started out positive and patient but eventually couldn’t understand my orgasm troubles, especially those who have had previous partners with “really big, intense orgasms.” I have tried counseling, reading advice in books and on the internet on how to achieve orgasms, talking to different GYNs and medical doctors, but I think my body is not able.

    I believe Acutane may have caused my ongoing, never-ending depression as well. However, as ironic as this may sound, I wouldn’t take my wonder-drug treatment by Acutane back. I actually wasn’t even able to get a boyfriend before Accutane because of my gross acne but quickly had men flocking around me post-treatment….the reason I don’t even know if I had a normal libido before treatment or not really (no boyfriend=no sex). Also, I do remember being sad as a kid so not sure if Accutane caused my depression to worsen or stick around longer, just not sure of it had anything to do with my depression or not. Who knows, could I have developed depression because of all the social rejection and teasing I experienced as a kid and therefore my lack of confidence because of my acne? That is likely.

    The fact is, I want to experience what “all girls experience” according to what my current partner told me. (He says he has asked many men he works with if their wives have this issue and also many girls he knows, and none that he has asked have even heard of this problem in girls, and think this problem is “wierd” for lack of a better word. It’s the same response I have gotten from every sexual partner I have had…only about 10 in total. They have all thought it was wierd and perplexing as I do too).

    I do get horny and I enjoy sex, but I have to use lube almost every single time and I have never had an orgasm and IT SUCKS!!! And after reading many of these posts, I guess I am not alone so good. Phew. Lol

    Whether Accutane caused my depression and/or orgasm trouble is all a big mystery, but something I question often. I do agree that it should be listed as a possible side effect.

    • Totally agree with Kim, but they will never admit this by putting ‘possible permanent sexual dysfunction’ on the PIL as a side effect, cos if they did no one with any sense would ever touch this stuff. You can always change your skin for the better – it may take a while, and even if there is scarring, laser therapy is fantastic, once the eruptions stop. Blue Light treatment is wonderful. Diet works. I know, my son had one of the worst cases of modular acne you can imagine, on his back, and chest. Dr Tony Chu, acne specialist in London achieved amazing results within a few months, which years of RoAccutane (Accutane) use prior to that, never did.

      But he died by prescripticide nevertheless, because of the mental and physical damage the drug had done to him. He had gained the good skin he longed for, paid for it himself, was delighted with it, but it meant nothing in the end, because RoAccutane-isotretinoin had ruined the rest of him. He was 32 when he died, started the drug when 21. He was a private sort of guy, didn’t discuss sexual dysfunction with us, his parents, but from something we discovered after his death, a text message sent around by an unpleasant woman he’d recently had some unsought contact with, it may well be that shame about this was a factor that drove him finally out of this world along with appallingly bullying treatment from a bigoted psychiatrist who would not listen.

      If interested you can read his story on RxISK/Blog as ‘RoAccutane – The Perfect Circle’ and ‘Roche and the Perfect Circle’. See also http://www.ollysfriendshipfoundation.org.uk, and it’s own Facebook page. We and other parents confronted the Directors of Roche in their own Boardroom about all these issues on 24.4.14 after a Protest staged outside their premises – it got us nowhere, including sexual dysfunction. One guy, still alive, explained it to them, face to face. Neither did going to Government who commissioned a further Report about the drug by the MHRA published in Nov 2014, which was, we all felt, another complete whitewash. Ironically, our son became so akathisic on various SSRIs, prescribed to counter the low mood from the acne drug he’d suffered for 11 years, that they eventually gave him some Olanzapine, an anti psychotic that can actually cause acne itself. It did. So he’d gone full circle, spent hundreds of pounds getting rid of it successfully with Dr Chu’s excellent non drug treatment, and then saw it creeping back again.

      I guess this is all good for business for Roche and their multi-billion profits from Accutane/RoAccutane-isotretinoin. The Perfect Circle just goes round and found, and as some folk drop out, there will always be new victims ready for kidnap, naturally wanting good skin again and believing what dermatologists tell them. Don’t throw away your life for this stuff if it’s damaged you, band together and mount more Protests. Never give up. But be aware, we are taking on a very powerful foe, well funded, and determined not to admit to the damage their drug has caused. Keep on posting your accounts, raising awareness, pass the word to friends, take RxISK reports to your doctors, believe in the rightness of your cause, and above all, believe in and be true to yourselves. None of this is your fault.

  61. I posted my experience with roaccutane two years ago with the same side effects of the male sex drive being low and struggle to get an erection . Only being on it for 3 months went of it straight away a luckily I’m back to my normal self , although still have few acne but my body feels the same , my erection is normal, my sex life is good. Since then I never looked back. If you see side effects in the early stages get of it straight away it’s not worth having clear skin and endure this torture,

  62. Accutane absolutely can cause extreme sexual dysfunction. I took Accutane as 14 year old boy, I am now 24 years old and can say my libido still practically non-existent. Nobody seems to have an answer to this. This is a life ruining side effect, which on its own should force the withdrawal of Accutane from being sold. This drug is far too toxic and powerful to be warrant use for a minor ailment such as acne.

    This side effect can be permanent, I have no idea how to fix it or where to begin looking for solutions.

    I warn you, boycott this drug, do not risk taking it. Its not worth it!

  63. Hi,

    I am currently taking Accutane and I am experiencing these sexual problems too. My morning erections are completely gone, I’m not able to get an erection from my thoughts but I can if I touch my penis. As well as this, my sperm has gone really watery and my testicles have gone smaller. I feel like this could affect my fertility long-term which is scaring me as I’m only 20 (soon-to-be 21).

    It’s literally the only big side effect that I have currently. At first I had itching but that’s eased off and I also have ringing in my left ear but I don’t know for sure if that’s to do with the tablets or not because I had ear issues prior to this. Also, I am struggling to poo a lot compared to what I previously was like.

    It’s a real worry and I’m considering quitting the drugs after a month of doing 40mg a day. My fear is my acne will return viciously because despite these issues my acne has improved a lot.

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