Dozens of these buttons flooded the United States Food and Drug Administration’s (FDA) headquarters at a meeting for the widely prescribed asthma/allergy medication, montelukast (brand name, Singulair). The message was simple: “The benefits did not outweigh the risks.” As each button approached the podium, the panel of experts heard gut-wrenching testimonials about the … [Read more...] about Montelukast: Beyond the Black Box
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Sexually Confused or Chemically Imbalanced Cosmopolitan
April's Cosmopolitan features How Depression Stole my Orgasm - an article on Sex for sure... but Sex and Depression or Sex and Antidepressants? It's worth downloading the full article and telling us what you think the message is. It opens with some pretty clear examples of how SSRIs have immediate effects on sex and can almost immediately wipe out sex for ever. There … [Read more...] about Sexually Confused or Chemically Imbalanced Cosmopolitan
Catch San Marino if you Can
There have been some major developments on the RxISK Prize front. First we are hovering around the $66,666 point – depending on how exchange rates go we may be wandering back and forth over this line as I write. More important however is that San Marino has raced out in front as the donor leading country. This is down to one important woman and a small population. Her … [Read more...] about Catch San Marino if you Can
Starship Corona: Captain’s Log
The use of psychiatric meds in the U.S., already sky-high, is on the rise as a result of Covid-19. That’s not surprising – it happened after the 9-11 attacks, the 2008 crash and other crises. This graph comes from “America’s State of Mind,” an April 2020 report from Express Scripts. In the month from February 15 to March 15, prescriptions for depression, anxiety and … [Read more...] about Starship Corona: Captain’s Log
Covid and the Market in Research
There are 3 bits to this post - an interview with Joan-Ramon Laporte. An article by Ariane Denoyel and a Q and A with Laporte and Healy. Laporte Interview As part of a series for ROAR Magazine, Frank Barat has run some striking interviews about aspects of the Covid pandemic not usually mentioned. Here is Joan-Ramon Laporte talking about the market in … [Read more...] about Covid and the Market in Research
Medications compromising Covid Infections
IN THE MIDST OF THE SARS-CoV-2 PANDEMIA, CAUTION IS NEEDED WITH COMMONLY USED DRUGS THAT INCREASE THE RISK OF PNEUMONIA. Joan-Ramon Laporte, M.D. Emeritus Professor of Clinical Pharmacology, Department of Pharmacology, Therapeutics and Toxicology Universitat Autònoma de Barcelona. Fundació Institut Català de Farmacologia. WHO Collaborating Centre for Research and Training … [Read more...] about Medications compromising Covid Infections
Snakes in a Love Drug 2
This image is widely viewed as a symbol of medicine. Many, particularly in America, owing to a bad mistake by the American Medical Association, would identify it as the Rod of Aesclepius, a healer in Ancient Greece. But its not a symbol of medicine - as it used to be at least - its the Caduceus of Hermes / Mercury - a symbol of commerce. The Rod of Aesclepius is down … [Read more...] about Snakes in a Love Drug 2
Snakes in a Love Drug on St Patricks Day
IJME In recent years the Indian Journal of Medical Ethics has been to the forefront in grappling with tricky issues in medical ethics and politics - topics that the best known medical journals and authorities should deal with but steer clear of. One of us (DH) had a growing awareness of IJME's lead on tricky issues, but became even more aware of it at the time of the … [Read more...] about Snakes in a Love Drug on St Patricks Day
Causes Sexual Dysfunction, Suicide and Birth Defects?
Everyone who reads RxISK posts will know that SSRI and related drugs (some antibiotics, painkillers, antihistamines and most antidepressants) can cause sexual dysfunction. This has been known since 1961. And that they can cause suicide. This has been known since 1959. And that they can cause birth defects. The first publication by an Australian obstetrician, William … [Read more...] about Causes Sexual Dysfunction, Suicide and Birth Defects?
The Politics of PSSD
Members of the British parliament In October 2019, we were contacted by a British PSSD sufferer who had done some excellent work in getting his Member of Parliament (MP), Steve McCabe, interested in the condition. We were informed that Mr. McCabe wanted to get a large group of MPs together to try and get some support for sufferers and hopefully stimulate interest in finding … [Read more...] about The Politics of PSSD