When did it begin? Post-SSRI Sexual Dysfunction (PSSD) officially made its debut in the peer-reviewed medical literature in 2006. Case reports were published that identified treatment-emergent sexual dysfunction that persisted after the antidepressant was stopped. The condition was given a name and its features were defined. This new literature also noted the significance … [Read more...] about The Early History of PSSD
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Roche and The Perfect Circle
Editorial Note: This is part 2 of the post by Heather and David Roberts - See RoAccutane and The Perfect Circle. Ever since in 2012 our son Olly died after using it, we have tried to learn what it does to the body and the mind. For the most terrifying thing about it, apart from the teratogenic damage to unborn babies, is that it can seriously, and we feel irreversibly, affect … [Read more...] about Roche and The Perfect Circle
RoAccutane and the Perfect Circle
Editorial Note: This post by Heather and David Roberts is about their son Olly and the struggles he and they had with the health system, acne and its treatments. Our son Olly had RoAccutane prescribed for him aged 21, getting ready to celebrate his birthday at Bristol University and wanting to look his best. He was studying Biological Sciences. His results from his first year … [Read more...] about RoAccutane and the Perfect Circle
Heartattack and Vine – and Plavix
Editorial Note: The first RxISK story was about Plavix - Fiona's Story. This anonymous account has striking overlaps with that. Plavix is clopidogrel. The grel group of drugs include 1tazigrel, dimetagrel and others. They function like expensive aspirins. They cause problems on withdrawal and can be lethal. But medics and nurses will bat the problems away and suggest that any … [Read more...] about Heartattack and Vine – and Plavix
Doctors: What do they know?
Editorial Note: This is an anonymous guest post. I started teaching in the early 1970’s, when to be a teacher was to be a professional, like a solicitor or a doctor. A few years later the Minister for Education, Margaret Thatcher, managed in one short speech to downgrade the status of teachers. At the time, she was trying to alleviate the shortage of teachers without spending … [Read more...] about Doctors: What do they know?
Dilemmas: advising others
Editorial Note: This post is by Sally Macgregor. I left a comment on: Stopping Antidepressants: Kenny’s dilemma, which contained this statement: ‘I think acknowledging that coming off the pills can end badly is absolutely crucial. For one thing it’s honest, and without honestly how can people begin to cope with the situation they find themselves in’ I also said that I had a … [Read more...] about Dilemmas: advising others
Transgender, Asexuality and SSRIs
Last week, there was a post Asexual, Transgender and SSRIs about possible links between antidepressant use in pregnancy or early childhood and a later development of asexuality. In recent weeks RxISK has had several emails asking about possible links between transgender issues or Gender Dysphoria and antidepressants. In one a woman wondered about a brother who went on … [Read more...] about Transgender, Asexuality and SSRIs
Asexual, Transgender & SSRIs
Last week's post about Antidepressants and Autistic Spectrum Disorder came with an article attached. This article was first sent to and first turned down by BMJ Open because it contained references to a set of animal studies. BMJ Open it turns out is a human studies only journal. The interest in the animal studies listed below is that animals conceiving and giving birth … [Read more...] about Asexual, Transgender & SSRIs
Autistic Spectrum Disorder and SSRIs
Five years ago, the Croen et al article in the Figure above appeared suggesting that antidepressant use in pregnancy can cause Autistic Spectrum Disorder (ASD). Pharmaceutical companies rushed to manage the risks - to them. What you do is you convene your experts and you put them in boxes, a teratology box, an animal studies box, an epidemiology box, a psychology box, a … [Read more...] about Autistic Spectrum Disorder and SSRIs
Bruce Springsteen: Born with an Inner Restlessness
Further excerpts from Bruce Springsteen's Born to Run. Bruce looks like he had a dependence syndrome and perhaps even organic damage or dysfunction linked to an antidepressant - See Born to Withdraw. Did he also have akathisia? Akathisia (restlessness, agitation & turmoil): A disorder characterized by an uncomfortable feeling of inner restlessness and inability to stay … [Read more...] about Bruce Springsteen: Born with an Inner Restlessness