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Catch San Marino if you Can

May 4, 2020 28 Comments

There have been some major developments on the RxISK Prize front. First we are hovering around the $66,666 point – depending on how exchange rates go we may be wandering back and forth over this line as I write. More important however is that San Marino has raced out in front as the donor leading country.  This is down to one important woman and a small population.  Her … [Read more...] about Catch San Marino if you Can

Causes Sexual Dysfunction, Suicide and Birth Defects?

March 3, 2020 35 Comments

Everyone who reads RxISK posts will know that SSRI and related drugs (some antibiotics, painkillers, antihistamines and most antidepressants) can cause sexual dysfunction. This has been known since 1961. And that they can cause suicide.  This has been known since 1959. And that they can cause birth defects. The first publication by an Australian obstetrician, William … [Read more...] about Causes Sexual Dysfunction, Suicide and Birth Defects?

The Politics of PSSD

February 18, 2020 34 Comments

Members of the British parliament In October 2019, we were contacted by a British PSSD sufferer who had done some excellent work in getting his Member of Parliament (MP), Steve McCabe, interested in the condition. We were informed that Mr. McCabe wanted to get a large group of MPs together to try and get some support for sufferers and hopefully stimulate interest in finding … [Read more...] about The Politics of PSSD

Gateway to the Soul

February 3, 2020 80 Comments

Read the accompanying Sex, Withdrawal and Boundaries post first.  We are looking for anyone interested in the material raised there to comment on or add to the set of questions below. We are so insensitive to the fact that our skin and gut principally, but also bladder and maybe the inner linings of our lungs, our boundary, likely sees, hears, tastes, smells and encounter … [Read more...] about Gateway to the Soul

Sex, Withdrawal and Boundaries

February 3, 2020 31 Comments

“Do you think studying monolayers of cells will tell you why you fall in love with a girl?" The quote comes from Rudolf Hess, who won the Nobel Prize for physiology in 1949.  His students remembered him as telling them never to study a neurotransmitter or even a cell without thinking about where this bit of the body comes from and what it is supposed to do. This is one of … [Read more...] about Sex, Withdrawal and Boundaries

What’s Sex Got to Do with It

January 23, 2020 29 Comments

This post gives the text of an article that has just been published online in the Journal of the Royal Society of Medicine - see Here. Another version of the material is in video form - Antidepressants and Sex: a Strange Story. Background In June 2019, in response to a petition, the European Medicines Agency (EMA) asked pharmaceutical companies to warn that sexual … [Read more...] about What’s Sex Got to Do with It

Everything’s in Hand: Isotretinoin and the Usual Guff

January 4, 2020 32 Comments

Niks aan de Hand - Nothing out of hand. This item has just appeared in the BMJ:  An expert group has been reconvened to review recent safety data relating to the acne drug isotretinoin (Roaccutane) and evaluate the risk of sexual and psychiatric adverse effects, including suicide. The Medicines and Healthcare Products Regulatory Agency’s isotretinoin expert working group … [Read more...] about Everything’s in Hand: Isotretinoin and the Usual Guff

Not the RxISK Manifesto

October 18, 2019 11 Comments

Last week's RxISK Manifesto post featured an article then just published in BMJ. The BMJ picture that went with the article looked like this.  This gives entirely the opposite message to the article. The article says a doctors job would be a lot more interesting if they listened and encouraged anyone consulting them to become researchers rather than problems.  It also … [Read more...] about Not the RxISK Manifesto

RxISK Manifesto

October 7, 2019 11 Comments

This post is close to identical to an article that has just appeared in the BMJ - Clinical Judgments, not Algorithms, are key to Patient Safety.   Immediately on taking a selective serotonin reuptake inhibitor (SSRI), most people have some genital anaesthesia.1 This may be aggravated on withdrawal of the drug and can remain for years after treatment has stopped, constituting … [Read more...] about RxISK Manifesto

PSSD Patient Experiences

September 25, 2019 45 Comments

New paper "If you wish to have such “syndrome” continue what you are doing ... read obscure studies and reviews in obscure databases and I can guarantee to you that you will have it till the end of your life!" Anyone who has experienced a serious side effect from a medication will know how difficult the conversation with your doctor can be. In our new paper, “Post-SSRI … [Read more...] about PSSD Patient Experiences

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