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Drug:

Reaction: EYE IRRITATION

20260101 - 20261231

No. 1 - 100

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No.
safetyreportid
occurcountry
patientonsetage
patientsex 1:M 2:F
Adverse reaction
Drug (openfda.generic_name, medicinalproduct)
1
26940399
US
 62 2
Ocular hyperaemia, Eye irritation, Eye pain, Eye swelling, Product quality issue, Accidental exposure to product,
ABALOPARATIDE, ABALOPARATIDE, ESTRADIOL, ESTRADIOL GEL 0.1%, ESTRADIOL TRANSDERMAL, ESTRADIOL,,
2
26940829
US
 80 2
Conjunctival ulcer, Ulcerative keratitis, Corneal infection, Eye irritation, Ocular hyperaemia, Eye pain, Persistent corneal epithelial defect,
ERLOTINIB HYDROCHLORIDE, ERLOTINIB HYDROCHLORIDE,
3
26942317
IN
 74 1
Inguinal hernia, Vision blurred, Vitreous floaters, Abdominal distension, Eye irritation, Asthenopia, Retinal haemorrhage, Dizziness, Eye pain, Eye pruritus, Eye disorder, Eye haemorrhage,
FARICIMAB,
4
26944032
US
 76 2
Accidental exposure to product, Product use issue, Mouth swelling, Swelling of nose, Oral pain, Eye irritation,
AMLODIPINE, CARVEDILOL,
5
26944521
US
Eye irritation,
LIFITEGRAST, ACOLTREMON,
6
26945430
US
 78 2
Eye irritation,
LEVOTHYROXINE SODIUM, ACOLTREMON, CELECOXIB, ROSUVASTATIN, PAROXETINE HYDROCHLORIDE, PANTOPRAZOLE SODIUM,
7
26934447
US
 1
Exophthalmos, Muscle spasms, Autophony, Lacrimation increased, Ocular hyperaemia, Ageusia, Eye irritation,
TEPROTUMUMAB, TEPROTUMUMAB,
8
26934774
BR
 49 2
Carcinoembryonic antigen increased, Colorectal cancer metastatic, Acne pustular, Fatigue, Eye irritation, Lacrimation increased, Pruritus, Erythema, Nausea, Somnolence, Pigmentation disorder, Dysuria, Malaise, Oral discomfort, Dysgeusia, Restlessness, Feeding disorder, Food intolerance, Skin haemorrhage, Skin fissures, Skin burning sensation, Urine abnormality, Memory impairment, Dysphagia,
PANITUMUMAB, DEXAMETHASONE, DEXAMETHASONE 1.5 MG,
9
26935225
US
 2
Eye irritation,
NAPHAZOLINE HYDROCHLORIDE AND PHENIRAMINE MALEATE,
10
26935662
US
 2
Pain, Eye disorder, Eye irritation, Vision blurred,
LIFITEGRAST,
11
26935950
US
 21 2
Eye irritation,
TRALOKINUMAB-LDRM, TRALOKINUMAB-LDRM,
12
26936107
2
Eye irritation,
ROSUVASTATIN, ACOLTREMON, METOPROLOL SUCCINATE, EXEMESTANE,
13
26936769
US
 28 2
Eye irritation, Eye pruritus, Eyelid margin crusting, Foreign body sensation in eyes,
DUPILUMAB,
14
26936964
US
 97 2
Eye irritation,
EXEMESTANE, ACOLTREMON, ROSUVASTATIN, METOPROLOL SUCCINATE, VITAMIN C, ERGOCALCIFEROL, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, PREDNISONE, TORSEMIDE, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG,
15
26937296
US
 72 1
Corneal abrasion, Dry eye, Eye irritation,
PERFLUOROHEXYLOCTANE, ACOLTREMON,
16
26937476
US
 66 2
Eye irritation,
CYCLOSPORINE OPHTHALMIC SOLUTION,
17
26937479
US
 72 2
Eye irritation,
CYCLOSPORINE OPHTHALMIC SOLUTION,
18
26937513
US
 72 2
Eye irritation, Eye pruritus,
CYCLOSPORINE OPHTHALMIC SOLUTION,
19
26937523
US
 60 2
Eye irritation,
CYCLOSPORINE OPHTHALMIC SOLUTION,
20
26937985
US
 82 2
Eye irritation,
LEVOTHYROXINE SODIUM, ACOLTREMON, METHENAMINE HIPPURATE, ESTRADIOL, ESTRADIOL GEL 0.1%, ESTRADIOL TRANSDERMAL, ESTRADIOL,, ASPIRIN, EZETIMIBE, ROSUVASTATIN, NEBIVOLOL HYDROCHLORIDE, VALSARTAN, VALSARTAN ORAL,
21
26938262
US
 81 2
Eye pruritus, Eye irritation, Skin tightness,
LEVOTHYROXINE SODIUM, ACOLTREMON, CALCITRIOL, CALCITRIOL CAPSULES 0.25 MCG, CALCITRIOL CAPSULES 0.5 MCG,
22
26940002
US
 63 1
Loss of consciousness, Lacrimation increased, Orthostatic hypotension, Acne, Eye irritation,
FOSCARBIDOPA/FOSLEVODOPA,
23
26931093
US
 88 1
Eye irritation, Ocular discomfort, Accidental overdose,
CYCLOSPORINE OPHTHALMIC SOLUTION,
24
26931097
US
 60 2
Eyelid pain, Ocular hyperaemia, Eyelid irritation, Eye pain, Eye irritation,
CYCLOSPORINE OPHTHALMIC SOLUTION,
25
26931099
US
 70 2
Eye irritation, Lacrimation increased,
CYCLOSPORINE OPHTHALMIC SOLUTION,
26
26931100
US
 86 1
Eye irritation,
CYCLOSPORINE OPHTHALMIC SOLUTION,
27
26931132
US
 62 2
Eye irritation,
CYCLOSPORINE OPHTHALMIC SOLUTION,
28
26931133
US
 65 2
Eye irritation, Eye pain,
CYCLOSPORINE OPHTHALMIC SOLUTION,
29
26931135
US
 74 2
Eye irritation,
CYCLOSPORINE OPHTHALMIC SOLUTION,
30
26931209
US
 85 1
Eye irritation,
CYCLOSPORINE OPHTHALMIC SOLUTION,
31
26931213
US
 67 2
Foreign body sensation in eyes, Eye irritation, Condition aggravated,
CYCLOSPORINE OPHTHALMIC SOLUTION,
32
26931217
US
 2
Lacrimation increased, Ocular hyperaemia, Dizziness, Eye irritation,
DUPILUMAB,
33
26931455
US
 34 2
Eye irritation,
DUPILUMAB,
34
26931667
EU
Septic shock, Off label use, Metabolic disorder, Fatigue, Mental disorder, Atrial fibrillation, Injury, Neutropenia, Urinary tract infection, Angiopathy, COVID-19, Benign neoplasm, Infusion related reaction, Renal disorder, COVID-19 pneumonia, Dyspnoea, Poisoning, Procedural complication, Nausea, Vision blurred, Neoplasm malignant, Neoplasm, Dry eye, Anaemia, Oedema peripheral, Arthralgia, Skin disorder, Hypertension, Cyst, Urinary tract disorder, Eye irritation, Pneumonia, Malnutrition, Diarrhoea, Cough, Infestation, Polyp, General symptom, Cardiac disorder, Spinal disorder, Investigation abnormal, Gastrointestinal disorder, Nervous system disorder, Respiratory disorder, Musculoskeletal disorder, Adverse event, Lymphatic disorder, Eye disorder, Administration site reaction, Mediastinal disorder, Blood disorder, Infection, Connective tissue disorder,
IBRUTINIB, RITUXIMAB,
35
26931855
US
 67 2
Eye irritation,
ACOLTREMON, METHOTREXATE, METHOTREXATE SODIUM,
36
26932494
US
 2
Oral herpes, Eye irritation, Oropharyngeal pain,
DUPILUMAB,
37
26932675
US
 46 1
Ocular hyperaemia, Eye irritation,
DUPILUMAB,
38
26933079
CA
 72 2
Malignant neoplasm progression, Fall, Contusion, Asthenia, Hospitalisation, Muscular weakness, Hypertension, Blood potassium decreased, Angioplasty, Malignant neoplasm progression, Gastric cancer, Headache, Migraine, Myalgia, Abdominal pain, Flatulence, Faeces discoloured, Nausea, Alopecia, Decreased appetite, Weight decreased, Breast discolouration, Insomnia, Pain in extremity, Off label use, Arthralgia, Diarrhoea, Abdominal pain upper, Off label use, Sinusitis, Eye infection, Anaemia, Pancreatic disorder, Vomiting, Nausea, Faeces discoloured, Abdominal pain upper, Polyp, Urinary tract infection, Fatigue, Diarrhoea, Abdominal distension, Stomach mass, Abdominal pain, Nausea, Vomiting, Diarrhoea, Fatigue, Polyp, Diarrhoea, Haemorrhoidal haemorrhage, Pain, Loss of personal independence in daily activities, Conjunctival laceration, Fall, Joint injury, Skin abrasion, Contusion, Pain, Fatigue, Pain, Nausea, Vomiting, Diarrhoea, Fall, Limb injury, Eye irritation, Walking aid user, Entropion, Asthenia, Fatigue,
LANREOTIDE ACETATE, LANREOTIDE ACETATE, LANREOTIDE ACETATE, LANREOTIDE ACETATE, LANSOPRAZOLE, CLONAZEPAM, ACETAMINOPHEN, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE, ACETAMINOPHEN, CHOLESTYRAMINE,
39
26933298
US
 73 2
Visual impairment, Dry skin, Skin fissures, Pruritus, Dry eye, Eye irritation,
DUPILUMAB,
40
26933361
US
 2
Eye irritation,
DUPILUMAB, ALBUTEROL SULFATE, ALBUTEROL, ALBUTEROL SULFATE, AZATHIOPRINE, BUPROPION, BUPROPION HYDROCHLORIDE, ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM, FLUTICASONE PROPIONATE, HYDROCHLOROTHIAZIDE,
41
26933770
US
 37 2
Eye irritation, Myalgia, Product use in unapproved indication,
DUPILUMAB,
42
26927533
US
 2
Eye disorder, Eye irritation, Eye pain, Eye pruritus,
CYCLOSPORINE,
43
26929424
IL
 2
Blindness transient, Photophobia, Eye pruritus, Eye irritation,
PROPYLENE GLYCOL EMULSION, PROPYLENE GLYCOL,
44
26929921
US
 5 1
Eye irritation, Pruritus, Inappropriate schedule of product administration,
DUPILUMAB,
45
26929925
US
 43 1
Ocular hyperaemia, Eye irritation,
DUPILUMAB,
46
26921312
US
 70 2
Eye swelling, Eye irritation, Eye pruritus, Erythema, Swelling face,
TIMOLOL MALEATE, TIMOLOL MALEATE OPHTHALMIC,
47
26921764
US
 86 1
Hypoacusis, Eye irritation,
BIMATOPROST, BIMATOPROST,
48
26922693
US
 26 1
Eye irritation, Nasopharyngitis, Nasal congestion, Cough, Oropharyngeal pain,
DUPILUMAB,
49
26922912
US
 56 1
Surgery, Hypoaesthesia, Infusion site haemorrhage, Infusion site bruising, Paraesthesia, Eye irritation, Catheter site nodule, Discomfort, Stress, Muscle twitching, Burning sensation, Dyskinesia, Anorgasmia, Catheter site induration, Catheter site haemorrhage, Infusion site reaction,
FOSCARBIDOPA/FOSLEVODOPA, FOSCARBIDOPA/FOSLEVODOPA,
50
26923525
US
 2
Lacrimation increased, Ocular hyperaemia, Eye irritation,
DUPILUMAB,
51
26923584
US
 2
Eye irritation, Eye pain,
CYCLOSPORINE, ACOLTREMON, ORAL SEMAGLUTIDE, FENOFIBRATE, LOSARTAN, AMLODIPINE,
52
26924414
BR
 86 2
Infarction, Cerebrovascular accident, Eye irritation, Blister, Product availability issue, Product container seal issue,
MOXIFLOXACIN HYDROCHLORIDE,
53
26924415
US
 77 1
Eye irritation,
CYCLOSPORINE OPHTHALMIC SOLUTION,
54
26924425
US
 63 1
Eye pain, Eye irritation,
CYCLOSPORINE OPHTHALMIC SOLUTION,
55
26924426
US
 69 2
Sneezing, Rhinorrhoea, Eye irritation, Underdose,
CYCLOSPORINE OPHTHALMIC SOLUTION,
56
26924427
US
 82 2
Eye irritation,
CYCLOSPORINE OPHTHALMIC SOLUTION,
57
26924914
US
 82 2
Eye irritation,
LEVOTHYROXINE SODIUM, ACOLTREMON, VALSARTAN, VALSARTAN ORAL, METHENAMINE HIPPURATE, ESTRADIOL, ESTRADIOL GEL 0.1%, ESTRADIOL TRANSDERMAL, ESTRADIOL,, ASPIRIN, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, EZETIMIBE, ROSUVASTATIN, NEBIVOLOL HYDROCHLORIDE,
58
26925045
US
 69 2
Eye irritation,
CYCLOSPORINE, ACOLTREMON,
59
26925535
US
 81 2
Eye irritation,
CYCLOSPORINE OPHTHALMIC SOLUTION,
60
26925646
US
 2
Eye irritation, Eye pain, Drug ineffective,
OLOPATADINE HYDROCHLORIDE,
61
26925650
US
 2
Eye irritation, Ocular hyperaemia,
OLOPATADINE HYDROCHLORIDE,
62
26925655
US
 2
Eye irritation, Expired product administered,
63
26925657
US
 76 2
Eye irritation,
OLOPATADINE HYDROCHLORIDE,
64
26925681
US
 1
Hypoaesthesia oral, Rash, Eye irritation,
DUPILUMAB,
65
26929535
67 2
Ocular hyperaemia, Eye irritation, Glassy eyes, Swelling of eyelid,
LOTILANER OPHTHALMIC SOLUTION,
66
26916992
US
 69 2
Eye irritation,
CYCLOSPORINE, LEVOTHYROXINE SODIUM, ACOLTREMON, METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, OXYCODONE, LOVASTATIN,
67
26917103
US
 67 2
Eye inflammation, Eye pruritus, Swelling of eyelid, Eye irritation,
CYCLOSPORINE, ACOLTREMON, LEVOTHYROXINE SODIUM,
68
26917897
US
 76 2
Eye pruritus, Eye irritation,
CYCLOSPORINE OPHTHALMIC SOLUTION,
69
26917898
US
 83 2
Eye irritation,
CYCLOSPORINE OPHTHALMIC SOLUTION,
70
26917900
US
 61 2
Eye irritation, Eye pain, Eye swelling,
CYCLOSPORINE OPHTHALMIC SOLUTION,
71
26917913
US
 90 2
Eye irritation,
CYCLOSPORINE OPHTHALMIC SOLUTION,
72
26917915
US
 71 2
Eye irritation,
CYCLOSPORINE OPHTHALMIC SOLUTION,
73
26917916
US
 70 2
Eye irritation, Vision blurred,
CYCLOSPORINE OPHTHALMIC SOLUTION,
74
26917919
US
 72 2
Eye irritation, Lacrimation increased,
CYCLOSPORINE OPHTHALMIC SOLUTION,
75
26918235
US
 2
Lethargy, Somnolence, Eye irritation, Eye pain, Headache,
76
26918545
US
 63 2
Syncope, Loss of consciousness, Lethargy, Myalgia, Hyperhidrosis, Eye irritation, Arthralgia, Dry eye, Extra dose administered,
DUPILUMAB,
77
26919030
US
 84 2
Eye irritation,
ACOLTREMON, LEVOTHYROXINE SODIUM,
78
26919033
US
 82 2
Ocular discomfort, Eye irritation,
ACOLTREMON, MICONAZOLE NITRATE, LEVOTHYROXINE SODIUM,
79
26919034
US
 2
Eye irritation,
ACOLTREMON, ROSUVASTATIN, LEVOTHYROXINE SODIUM,
80
26919036
US
 54 2
Drug ineffective, Eye irritation,
ACOLTREMON,
81
26919038
US
 65 2
Eye irritation,
ACOLTREMON,
82
26919039
US
 71 2
Eye irritation,
ACOLTREMON, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, FAMOTIDINE, HYDROCHLOROTHIAZIDE, LOSARTAN, METOPROLOL TARTRATE, METOROPROLOL TARTRATE, METOPROLOL, ALIROCUMAB, SERTRALINE HYDROCHLORIDE,
83
26919040
US
 72 2
Eye pain, Eye irritation,
ACOLTREMON, CLOBETASOL PROPIONATE, CLOBETASOL PROPIONATE OINTMENT USP, 0.05%, DESVENLAFAXINE SUCCINATE, ESTRADIOL, ESTRADIOL GEL 0.1%, ESTRADIOL TRANSDERMAL, ESTRADIOL,, FAMOTIDINE, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG,
84
26919041
US
 69 2
Lacrimation increased, Eye irritation, Drug ineffective, Product administration interrupted,
ACOLTREMON, ACOLTREMON, GOLIMUMAB,
85
26919043
US
 89 2
Ocular discomfort, Eye irritation,
ACOLTREMON, ATENOLOL, GABAPENTIN, LOTEPREDNOL ETABONATE, PERFLUOROHEXYLOCTANE, SIMVASTATIN,
86
26919044
US
 86 2
Headache, Eye irritation,
ACOLTREMON, BUPROPION, ESTRADIOL, IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN TABLET, FILM COATED, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE, LEVALBUTEROL HYDROCHLORIDE, LOVASTATIN, MONTELUKAST, RIVAROXABAN,
87
26919047
US
 55 2
Ocular discomfort, Eye irritation,
ACOLTREMON,
88
26919048
US
 58 2
Eye irritation,
ACOLTREMON, PANTOPRAZOLE, ROSUVASTATIN,
89
26919051
US
 64 2
Drug ineffective, Eyelid pain, Eye irritation,
ACOLTREMON,
90
26919055
US
 72 2
Vision blurred, Foreign body sensation in eyes, Eye irritation, Drug ineffective,
ACOLTREMON, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, CLOPIDOGREL, CLOPIDOGREL BISULFATE, DILTIAZEM HYDROCHLORIDE, DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE TABLETS, EZETIMIBE, EMPAGLIFLOZIN, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, ERGOCALCIFEROL,
91
26919056
US
 83 2
Eye irritation,
ACOLTREMON, LORAZEPAM,
92
26919058
US
 65 2
Eye irritation,
ACOLTREMON,
93
26919061
US
 72 2
Dry eye, Ocular hyperaemia, Eye irritation,
ACOLTREMON, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM,
94
26919065
US
 60 2
Dry eye, Eye irritation,
ACOLTREMON, ESTRADIOL, ESTRADIOL GEL 0.1%, ESTRADIOL TRANSDERMAL, ESTRADIOL,, GABAPENTIN, LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE, PROGESTERONE,
95
26919067
US
 65 1
Eye irritation,
ACOLTREMON,
96
26919070
US
 78 2
Eye irritation,
ACOLTREMON, LISINOPRIL, OMEPRAZOLE MAGNESIUM, CYCLOSPORINE, BUDESONIDE AND FORMOTEROL FUMARATE DIHYDRATE, BUPROPION HYDROCHLORIDE,
97
26919072
US
 78 2
Ocular hyperaemia, Eye irritation,
ACOLTREMON,
98
26919076
US
 71 2
Lacrimation increased, Dry eye, Eye irritation,
ACOLTREMON, LORAZEPAM, CALCIUM, SUCRALFATE, FOLIC ACID, GABAPENTIN, ESCITALOPRAM, METHOTREXATE, METHOTREXATE SODIUM, MINOXIDIL, MINOXIDIL FOAM 5% (WOMENS), FAMOTIDINE, PREDNISONE, PANTOPRAZOLE SODIUM, AVACOPAN, TEMAZEPAM, ACETAMINOPHEN, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE, ACETAMINOPHEN, ERGOCALCIFEROL,
99
26919077
US
 82 2
Vision blurred, Eye irritation,
ACOLTREMON, ZANUBRUTINIB, HYDROCHLOROTHIAZIDE, LISINOPRIL, POTASSIUM CHLORIDE, POTASSIUM CHLORIDE EXTENDED-RELEASE, POTASSIUM CHLORIDE, DEXTROSE MONOHYDRATE, POTASSIUM CHLORIDE ORAL,
100
26919079
US
 54 2
Eye irritation,
ACOLTREMON, BENZTROPINE, LURASIDONE HYDROCHLORIDE, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG,

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last_updated

2026-07-30

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