Drug Search by Year (Detail)

26501038

US

Mucormycosis, Hepatic infection fungal, Disseminated mucormycosis, Respiratory failure, Acute kidney injury, Hepatic artery aneurysm, Hepatic necrosis, Hepatic haemorrhage,

TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, PREDNISONE, MYCOPHENOLIC ACID, MYCOPHENILIC ACID, METHYLPREDNISOLONE,

26501051

Acute kidney injury, Dehydration, Diarrhoea, Vomiting, Food intolerance, Prerenal failure,

SEMAGLUTIDE,

26501186

ET

Multiple organ dysfunction syndrome, Intentional overdose, Bradycardia, Vomiting, Oedema, Lethargy, Peripheral coldness, Bradyarrhythmia, Hypotension, Hypoxia, Pleural effusion, Rhythm idioventricular, Acute kidney injury, Toxicity to various agents, Respiratory distress, Distributive shock, Cardiac arrest, Non-cardiogenic pulmonary oedema,

AMLODIPINE BESYLATE, DICLOFENAC, DICLOFENAC SODIUM,

26501517

West Nile viral infection, Dehydration, Acute kidney injury,

IXEKIZUMAB, PREDNISONE,

26501686

MY

Staphylococcal scalded skin syndrome, Urosepsis, Acute kidney injury,

IXEKIZUMAB, IXEKIZUMAB, IXEKIZUMAB, IXEKIZUMAB, IXEKIZUMAB,

26501818

US

Nephropathy toxic, Renal tubular necrosis, Acute kidney injury,

ROSUVASTATIN CALCIUM, ROSUVASTATIN CALCIUM, ROSUVASTATIN CALCIUM, IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN TABLET, FILM COATED, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE, CARVEDILOL, HYDROCHLOROTHIAZIDE, VITAMIN C, ZINC SULFATE, ZINC SULFATE INJECTION,, ZINC SULFATE INJECTION, PANTOPRAZOLE SODIUM, PANTOPRAZOLE, PANTOPRAZOLE SODIUM IN 0.9% SODIUM CHLORIDE, PANTOPRAZOLE SODIUM INJECTION, OLOPATADINE, GABAPENTIN, FISH OIL, BUDESONIDE, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), ROSUVASTATIN,

26501856

US

Malignant neoplasm progression, Acute kidney injury, Cytopenia,

PEMBROLIZUMAB,

26501859

JP

Hepatitis fulminant, Acute kidney injury, Hyperkalaemia, Pancreatitis,

AVELUMAB,

26502135

US

Nephropathy toxic, Renal tubular necrosis, Acute kidney injury,

ROSUVASTATIN CALCIUM, ROSUVASTATIN CALCIUM, ROSUVASTATIN CALCIUM, IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN TABLET, FILM COATED, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE, CARVEDILOL, HYDROCHLOROTHIAZIDE, VITAMIN C, ZINC SULFATE, ZINC SULFATE INJECTION,, ZINC SULFATE INJECTION, PANTOPRAZOLE SODIUM, PANTOPRAZOLE, PANTOPRAZOLE SODIUM IN 0.9% SODIUM CHLORIDE, PANTOPRAZOLE SODIUM INJECTION, OLOPATADINE, GABAPENTIN, FISH OIL, BUDESONIDE, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), ROSUVASTATIN,

26502441

GB

Renal impairment, Acute kidney injury,

TIRZEPATIDE,

26502592

US

Shock, Thyrotoxic crisis, Acute kidney injury, Ischaemic hepatitis, Peripheral ischaemia, Peripheral arterial occlusive disease, Intestinal ischaemia, Cardiogenic shock, Distributive shock, Thyroiditis, Graves^ disease, Unmasking of previously unidentified disease,

26502651

EU

Acute kidney injury, Diarrhoea, Pyrexia, Dyspnoea exertional, Oliguria, Pneumonia, Pancytopenia, Metabolic acidosis, Hyponatraemia, Haematuria, Sepsis,

PEMBROLIZUMAB, CARBOPLATIN, CILOSTAZOL, LINAGLIPTIN AND METFORMIN HYDROCHLORIDE, ROSUVASTATIN CALCIUM, BISOPROLOL FUMARATE, PEMETREXED, PEMETREXED DISODIUM,

26506637

Nephropathy, Vision blurred, Peripheral swelling, Dyspnoea, Hypertension, Acute kidney injury, Orthopnoea, Dialysis,

APIXABAN,

26515790

Mental status changes, Acute kidney injury, Hyperkalaemia, Diabetic ketoacidosis,

CAPIVASERTIB, CAPIVASERTIB, FULVESTRANT, FULVESTRANT,

26497453

EU

Acute kidney injury, Cardio-respiratory arrest, Ventricular fibrillation, Suicidal behaviour,

TRAMADOL HYDROCHLORIDE, LORAZEPAM,

26497479

GB

Fournier^s gangrene, Anal abscess, Sepsis, Septic shock, Acute kidney injury,

DAPAGLIFLOZIN, DAPAGLIFLOZIN, FUROSEMIDE, EPLERENONE, SACUBITRIL AND VALSARTAN, BISOPROLOL FUMARATE, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG,

26497809

EU

Hypertransaminasaemia, Acute kidney injury, Dermatomyositis, Hyperglycaemic seizure, Myocarditis, Hepatitis, Skin abrasion,

NIVOLUMAB, RAMIPRIL, DAPAGLIFLOZIN,

26497901

US

Atrioventricular block complete, Intentional overdose, Acute kidney injury, Hypotension,

AMLODIPINE, MECLIZINE HCL 12.5 MG, MECLIZINE HCL 25 MG, MECLIZINE HYDROCHLORIDE, MECLIZINE, MECLIZINE HCL 25MG, MECLIZINE HCL 12.5MG,

26576621

Device defective, Implant site infection, Pseudomonas infection, Bacterial infection, Osteomyelitis, Abscess neck, Cellulitis, Acute kidney injury, Pneumothorax, Oedema,

CEFEPIME HYDROCHLORIDE, CEFEPIME,

26496726

US

Pneumonia, Aphthous ulcer, Acute kidney injury, Septic shock, Encephalopathy, Respiratory failure, Pancytopenia, Cellulitis,

UPADACITINIB, METHOTREXATE, METHOTREXATE SODIUM, VANCOMYCIN HYDROCHLORIDE, VANCOMYCIN, TAZOBACTAM SODIUM AND PIPERACILLIN SODIUM, PIPERACILLIN SODIUM AND TAZOBACTAM SODIUM, EPOPROSTENOL, SARILUMAB, ARIPIPRAZOLE ORALLY DISINTEGRATING, ARIPIPRAZOLE, ARIPIPRAZOLE ORAL, ALBUTEROL SULFATE, ALBUTEROL, ATORVASTATIN CALCIUM, GABAPENTIN, HYDROCHLOROTHIAZIDE, INSULIN ASPART INJECTION, INSULIN ASPART, INSULIN DEGLUDEC, LEVOTHYROXINE SODIUM, LOSARTAN, METOPROLOL TARTRATE, METOPROLOL, PANTOPRAZOLE SODIUM, SEMAGLUTIDE, ORAL SEMAGLUTIDE, SUMATRIPTAN, CETIRIZINE HYDROCHLORIDE, DIPHENHYDRAMINE HYDROCHLORIDE, FERROUS SULFATE, FLUTICASONE PROPIONATE, ACETAMINOPHEN, CHLORPHENIRAMINE MALEATE, PHENYLEPHRINE HCL, KETOCONAZOLE, LAMOTRIGINE, MELATONIN, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, METHOCARBAMOL, NAPROXEN SODIUM, NAPROXEN SODIUM 220MG, NAPROXEN SODIUM, COATED TABLETS, NAPROXEN SODIUM TABLET, COATED, FOLIC ACID,

26496952

GB

Rhabdomyolysis, Dilated cardiomyopathy, Ischaemic cardiomyopathy, Cardiac arrest, Hyperkalaemia, Acute kidney injury, Contraindicated product administered,

SIMVASTATIN, CLARITHROMYCIN, CLARITHROMYCIN,

26497182

EU

Distributive shock, Coma, Hyperkalaemia, Acidosis, Acute kidney injury, Poisoning deliberate,

LORAZEPAM, LORAZEPAM, ALPRAZOLAM, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, PROPRANOLOL HYDROCHLORIDE, PROPRANOLOL HYDROCHLORIDE,

26497200

EU

Enteritis, Pancytopenia, Acute kidney injury,

PEMETREXED, PEMETREXED DISODIUM, PEMBROLIZUMAB, AZELASTINE HYDROCHLORIDE AND FLUTICASONE PROPIONATE, EZETIMIBE, LANSOPRAZOLE, NICARDIPINE HYDROCHLORIDE, NICARDIPINE, RAMIPRIL, FLUTICASONE FUROATE, UMECLIDINIUM BROMIDE AND VILANTEROL TRIFENATATE,

26497214

EU

Eosinophilia, Acute kidney injury, Hepatitis, Agranulocytosis,

FLUCONAZOLE, CLINDAMYCIN PHOSPHATE, CLINDAMYCIN, COLCHICINE,

26497313

EU

Acute kidney injury, Drug interaction,

METHOTREXATE, METHOTREXATE SODIUM, ZOLEDRONIC ACID,

26491927

EU

Acute kidney injury, Hypovolaemic shock, Electrocardiogram QRS complex prolonged, Hypoglycaemia, Hyperkalaemia, Lactic acidosis,

ENALAPRIL, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CIPROFOLXACIN, CIPROFLOXACIN TABLETS,

26492049

AU

Hyperkalaemia, Dehydration, Acute kidney injury, Lactic acidosis, Hypoglycaemia, Drug interaction,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, AMLODIPINE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, SEMAGLUTIDE,

26492206

EU

Acute kidney injury,

MANNITOL,

26492236

Rhabdomyolysis, Acute kidney injury, Hepatic function abnormal, Neurotoxicity, Drug interaction,

KETOCONAZOLE, KETOCONAZOLE FOAM, KETOCONAZOLE CREAM, 2%, CYCLOSPORINE, SIMVASTATIN,

26492263

EU

Enteritis, Pancytopenia, Acute kidney injury,

PEMETREXED, PEMETREXED DISODIUM, PEMBROLIZUMAB, AZELASTINE HYDROCHLORIDE AND FLUTICASONE PROPIONATE, LANSOPRAZOLE, FLUTICASONE FUROATE, UMECLIDINIUM BROMIDE AND VILANTEROL TRIFENATATE, RAMIPRIL, EZETIMIBE, NICARDIPINE HYDROCHLORIDE, NICARDIPINE,

26492302

GB

Acute kidney injury, Dysuria, Oliguria, Urinary retention,

IBRUTINIB, IBRUTINIB, IBRUTINIB, IBRUTINIB, IBRUTINIB, IBRUTINIB, IBRUTINIB, IBRUTINIB, IBRUTINIB,

26492333

US

Respiratory failure, Mucormycosis, Hepatic infection fungal, Disseminated mucormycosis, Hepatic artery aneurysm, Hepatic haemorrhage, Hepatic necrosis, Acute kidney injury,

TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, METHYLPREDNISOLONE, MYCOPHENOLIC ACID, MYCOPHENILIC ACID, PREDNISONE,

26492455

IN

Cardiac arrest, Hypoalbuminaemia, Cholestasis, Electrolyte imbalance, Acute kidney injury, Pancytopenia, Myelosuppression, Pneumonia acinetobacter, Septic shock, Cellulitis, Soft tissue infection, Off label use,

MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, METHYLPREDNISOLONE,

26492586

GB

Lactic acidosis, Coma scale abnormal, Oxygen saturation decreased, Loss of consciousness, Mydriasis, Respiratory depression, Overdose, Pyrexia, Acute kidney injury,

IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN TABLET, FILM COATED, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE, SERTRALINE HYDROCHLORIDE, CENOBAMATE, VALPROATE SODIUM, FAMOTIDINE, TERBINAFINE HYDROCHLORIDE, TERBINAFINE, LANSOPRAZOLE,

26493053

EU

Acute kidney injury,

PEMBROLIZUMAB,

26493161

GB

Speech disorder, Muscle atrophy, Dysphagia, Hyperphosphataemia, Hypocalcaemia, Acute kidney injury, Myositis, Rhabdomyolysis, Weight decreased, Asthenia,

METOCLOPRAMIDE, METOCLOPRAMIDE HYDROCHLORIDE, FINASTERIDE, PANTOPRAZOLE, RAMIPRIL,

26493365

EU

Acute kidney injury,

CANDESARTAN, CISPLATIN, CISPLATIN, PEMBROLIZUMAB,

26493556

Coccidioidomycosis, Acid-base balance disorder mixed, Acute respiratory distress syndrome, Septic shock, Pneumonia necrotising, Cardiac arrest, Acute kidney injury, Hypoxic-ischaemic encephalopathy, Myopathy, Meningitis,

LEVOFLOXACIN, LEVOFLOXACIN IN 5% DEXTROSE, LEVOFLOXACIN, LEVOFLOXACIN IN 5% DEXTROSE, CEFTRIAXONE, CEFTRIAXONE SODIUM, DEXAMETHASONE, DEXAMETHASONE 1.5 MG, OSELTAMIVIR, OSELTAMIVIR PHOSPHATE,

26493599

US

Neuroleptic malignant syndrome, Device related sepsis, Acute kidney injury, Dehydration,

RISPERIDONE, OLANZAPINE, QUETIAPINE, BREXPIPRAZOLE,

26493623

EU

Acute kidney injury,

FUROSEMIDE, FUROSEMIDE, SACUBITRIL AND VALSARTAN,

26493746

US

Acute kidney injury,

METOPROLOL SUCCINATE, METOPROLOL SUCCINATE ER TABLETS, LISINOPRIL, NAPROXEN SODIUM, NAPROXEN SODIUM 220MG, NAPROXEN SODIUM, COATED TABLETS, NAPROXEN SODIUM TABLET, COATED, BISACODYL, BISACODYL SUPPOSITORIES, BISCODYL, DICLOFENAC SODIUM, DICLOFENAC SODIUM TOPICAL, DICLOFENAC SODIUM TOPICAL GEL, 1%, DICLOFENAC, DICLOFENAC SODIUM 1%, DULOXETINE HYDROCHLORIDE, DULOXETINE, GABAPENTIN, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, ROSUVASTATIN CALCIUM, PROCHLORPERAZINE MALEATE, MORPHINE SULFATE, CALCIUM, DENOSUMAB, LEUPROLIDE ACETATE,

26493749

GB

Acute kidney injury,

FUROSEMIDE,

26493947

EU

Clostridium difficile colitis, Staphylococcal skin infection, Febrile neutropenia, Acute kidney injury,

CYCLOPHOSPHAMIDE FOR INJECTION, CYCLOPHOSPHAMIDE, CYCLOPHOSPHAMIDE INJECTION, SOLUTION, CYCLOPHOSPHAMIDE FOR INJECTION, CYCLOPHOSPHAMIDE, CYCLOPHOSPHAMIDE INJECTION, SOLUTION, CARBOPLATIN, CARBOPLATIN, ETOPOSIDE, CISPLATIN, CISPLATIN,

26494076

EU

Acute kidney injury,

LEVETIRACETAM, LEVETIRACETAM IN SODIUM CHLORIDE, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION,

26494134

IN

Cellulitis, Soft tissue infection, Septic shock, Pneumonia acinetobacter, Myelosuppression, Hypoalbuminaemia, Cholestasis, Cardiac arrest, Electrolyte imbalance, Acute kidney injury, Pancytopenia,

MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, METHYLPREDNISOLONE,

26494356

EU

Acute kidney injury,

TORSEMIDE, TORSEMIDE,

26494359

EU

Acute kidney injury, Malaise, Vomiting, Hypokalaemia, Dehydration, Diarrhoea,

CAPECITABINE,

26494367

BR

Acute kidney injury, Ageusia, Nasopharyngitis, Asthenia, Fatigue, Decreased appetite, Diarrhoea,

ABEMACICLIB, ABEMACICLIB, ABEMACICLIB, SPIRONOLACTONE, INDAPAMIDE, HYDRALAZINE HYDROCHLORIDE,

26494383

US

Rhabdomyolysis, Chromaturia, Acute kidney injury, Blood creatinine increased, Myositis, Muscular weakness, Gait disturbance, Myoglobinuria,

IMATINIB, ROSUVASTATIN,

26494474

Acute kidney injury, Acidosis hyperchloraemic, Urinary tract infection, Vomiting,

26494741

IN

Nephropathy, Acute kidney injury,

ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, APIXABAN, APIXABAN, SILDENAFIL CITRATE, SILDENAFIL, SILDENAFIL POWDER,,

26494825

EU

Hypokalaemia, Hypocalcaemia, Acute kidney injury, Blood alkaline phosphatase increased,

ENFORTUMAB VEDOTIN, ENFORTUMAB VEDOTIN, ENFORTUMAB VEDOTIN, MIRABEGRON, SACUBITRIL AND VALSARTAN, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, ALLOPURINOL, BISOPROLOL FUMARATE, FOLIC ACID, FUROSEMIDE, SPIRONOLACTONE, FERROUS SULFATE, AMLODIPINE VALSARTAN AND HYDROCHLOROTHIAZIDE, DIGOXIN,

26494849

IN

Nephropathy, Acute kidney injury,

CARVEDILOL, SILDENAFIL CITRATE, SILDENAFIL, SILDENAFIL POWDER,,

26494954

KR

Acute kidney injury, Product use in unapproved indication,

GABAPENTIN, GABAPENTIN, GABAPENTIN, GABAPENTIN, AMITRIPTYLINE HYDROCHLORIDE, AMITRIPTYLINE HYDROCHLORIDE, AMITRIPTYLINE HYDROCHLORIDE, AMITRIPTYLINE HYDROCHLORIDE, LEVOFLOXACIN, LEVOFLOXACIN IN 5% DEXTROSE, LEVOFLOXACIN, LEVOFLOXACIN IN 5% DEXTROSE, LEVOFLOXACIN, LEVOFLOXACIN IN 5% DEXTROSE, LEVOFLOXACIN, LEVOFLOXACIN IN 5% DEXTROSE,

26495216

CN

Acute kidney injury, Respiratory distress, Rhabdomyolysis, Ventricular tachycardia, Condition aggravated, Pyrexia, Confusional state, Mental fatigue, Tachypnoea, Hypertonia, Blood pressure decreased, Hyperhidrosis, Tremor, Neuroleptic malignant syndrome, Serotonin syndrome, Hallucination, Seizure, Muscle rigidity, Nausea, Vomiting, Tachycardia, Intentional overdose,

SERTRALINE HYDROCHLORIDE, SERTRALINE HYDROCHLORIDE, SERTRALINE HYDROCHLORIDE, SERTRALINE HYDROCHLORIDE, QUETIAPINE, QUETIAPINE, OXAZEPAM, OXAZEPAM, OLANZAPINE,

26495873

EU

Acute kidney injury,

PEMBROLIZUMAB,

26496106

EU

Gastroenteritis Escherichia coli, Clostridium difficile colitis, Acute kidney injury,

CEMIPLIMAB-RWLC,

26496422

GB

Malaise, Syncope, Rhabdomyolysis, Acute kidney injury,

CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE,

26496450

EU

Acute kidney injury, Renal tubular injury,

PANTOPRAZOLE, OSIMERTINIB,

26496524

CO

Acute kidney injury,

ROSUVASTATIN, ROSUVASTATIN,

26496583

EU

Acute kidney injury, Prostatomegaly, Haemodynamic instability, Hypotension, Asthenia,

TIRZEPATIDE, TIRZEPATIDE, TIRZEPATIDE, TIRZEPATIDE, TIRZEPATIDE, TIRZEPATIDE, TIRZEPATIDE, TIRZEPATIDE, TIRZEPATIDE, NICARDIPINE,

26500267

Acute kidney injury, Generalised oedema, Ischaemic hepatitis, Pericardial effusion, Cardiac failure, Respiratory failure, Ascites,

AMBRISENTAN, SILDENAFIL CITRATE, SILDENAFIL, SILDENAFIL POWDER,, WARFARIN, EMPAGLIFLOZIN, ROSUVASTATIN, DILTIAZEM HYDROCHLORIDE, FUROSEMIDE, NALOXONE HYDROCHLORIDE NASAL, NALOXONE HYDROCHLORIDE, VALACYCLOVIR, VALACYCLOVIR HYDROCHLORIDE,

26500338

Acute kidney injury, Drug clearance decreased,

METHOTREXATE, METHOTREXATE SODIUM,

26485738

Acute kidney injury,

CYCLOSPORINE,

26485978

US

Acute kidney injury, Off label use, Off label use,

CYCLOSPORINE, HYDROXYCHLOROQUINE, TADALAFIL, METHOTREXATE, METHOTREXATE SODIUM,

26486004

US

Acute kidney injury, Fanconi syndrome acquired,

DOXORUBICIN, MESNA, MESNA INJECTION, IFOSFAMIDE,

26486358

EU

Acute kidney injury, Hyperhidrosis, Pallor, Dyspnoea, Palpitations, Vomiting, Emotional distress, Blood bicarbonate decreased, Fatigue, Blood lactic acid increased, Metabolic acidosis, Feeling abnormal, Acidosis, Hypotension, Lactic acidosis, Renal impairment, Drug interaction, Abdominal pain upper,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, INSULIN GLARGINE, CANAGLIFLOZIN, CANAGLIFLOZIN,

26486828

Rhabdomyolysis, Hyperkalaemia, Ischaemic cardiomyopathy, Acute kidney injury, Cardiac arrest, Loss of personal independence in daily activities, Blood creatinine increased, Contraindicated product administered, Condition aggravated, Contraindicated product prescribed, Product prescribing issue,

SIMVASTATIN, CLARITHROMYCIN,

26487404

BR

Acute kidney injury, Septic shock,

IBRUTINIB,

26487932

EU

Gastrointestinal disorder, Acute kidney injury,

26487958

US

Suicide attempt, Acute kidney injury, Depressed level of consciousness, Toxicity to various agents, Haemodynamic instability, Blood creatinine increased, Blood potassium decreased, Overdose, Vomiting, Hypotension,

LOSARTAN POTASSIUM, LOSARTAN,

26488030

Heart failure with reduced ejection fraction, Multiple organ dysfunction syndrome, Sepsis, Acute kidney injury, Stevens-Johnson syndrome, Toxic epidermal necrolysis,

CIPROFLOXACIN, CIPROFLOXACIN HYDROCHLORIDE, CIPROFOLXACIN, CIPROFLOXACIN TABLETS,

26488274

Acute kidney injury, Hyperkalaemia, Toxicity to various agents, Off label use,

TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, METHYLPREDNISOLONE, METHYLPREDNISOLONE, BASILIXIMAB, BASILIXIMAB, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, NITRIC OXIDE,

26488473

EU

Myopathy toxic, Acute kidney injury, Muscular weakness,

ROSUVASTATIN CALCIUM, ITRACONAZOLE, METHOTREXATE, METHOTREXATE SODIUM,

26488784

GB

Overdose, Coma scale abnormal, Acute kidney injury, Lactic acidosis,

IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN TABLET, FILM COATED, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE, CENOBAMATE, SERTRALINE, FAMOTIDINE, TERBINAFINE HYDROCHLORIDE, TERBINAFINE, LANSOPRAZOLE,

26488844

EU

Acute kidney injury, Renal tubular injury,

PANTOPRAZOLE, OSIMERTINIB,

26488885

US

Neuroleptic malignant syndrome, Dehydration, Acute kidney injury, Renal failure, Drug ineffective, Rhabdomyolysis,

QUETIAPINE, LORAZEPAM, LORAZEPAM, OLANZAPINE, BREXPIPRAZOLE, RISPERIDONE,

26489292

IN

Sarcopenia, Neuropathy peripheral, Hyperkalaemia, Impaired gastric emptying, Encephalopathy, Cytomegalovirus viraemia, Acute kidney injury, Stenotrophomonas sepsis, Candida sepsis, Thrombocytopenia, Off label use,

TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, METHYLPREDNISOLONE,

26489295

EU

Acute kidney injury,

CYCLOSPORINE,

26489717

US

Enteritis, Acute kidney injury, Lactic acidosis, Colitis microscopic, Hypokalaemia, Haemoglobin decreased, Weight decreased, Hypomagnesaemia,

26490193

US

Nephritis, Subcapsular renal haematoma, Glomerulonephritis rapidly progressive, Acute kidney injury, Shock haemorrhagic, Lupus-like syndrome, Anti-neutrophil cytoplasmic antibody positive vasculitis,

HYDRALAZINE HYDROCHLORIDE, PHENYTOIN, FLUOXETINE HYDROCHLORIDE, FLUOXETINE, NITROGLYCERIN, AMLODIPINE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, TORSEMIDE, PANTOPRAZOLE, CARVEDILOL,

26490325

US

Drug eruption, Renal tubular necrosis, Acute kidney injury, Eosinophilia,

VANCOMYCIN HYDROCHLORIDE, VANCOMYCIN, VANCOMYCIN HYDROCHLORIDE, VANCOMYCIN, VANCOMYCIN HYDROCHLORIDE, VANCOMYCIN, PIPERACILLIN SODIUM AND TAZOBACTAM SODIUM, PIPERACILLIN AND TAZOBACTAM, PIPERACILLIN SODIUM,TAZOBACTAM SODIUM, PIPERACILLIN SODIUM AND TAZOBACTAM SODIUM, PIPERACILLIN AND TAZOBACTAM, PIPERACILLIN SODIUM,TAZOBACTAM SODIUM, PIPERACILLIN SODIUM AND TAZOBACTAM SODIUM, PIPERACILLIN AND TAZOBACTAM, PIPERACILLIN SODIUM,TAZOBACTAM SODIUM,

26490789

US

Acute kidney injury,

PANTOPRAZOLE, ROSUVASTATIN, ROSUVASTATIN, BUDESONIDE, CARVEDILOL, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), FISH OIL, GABAPENTIN, OLOPATADINE, VITAMIN C, ZINC SULFATE, ZINC SULFATE INJECTION,, ZINC SULFATE INJECTION, IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN TABLET, FILM COATED, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE, HYDROCHLOROTHIAZIDE,

26490940

US

Acute kidney injury, Nephrostomy, Blood magnesium decreased, Blood potassium increased, Blood cholesterol increased, Asthma, Off label use,

ENCORAFENIB, BINIMETINIB,

26491140

EC

Acute kidney injury, Chronic kidney disease, Seizure, Metabolic disorder, Hypotension, Infection,

TRIENTINE TETRAHYDROCHLORIDE, TRIENTINE TETRAHYDROCHLORIDE, TRIENTINE TETRAHYDROCHLORIDE,

26491366

US

Acute kidney injury,

VENETOCLAX, IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN TABLET, FILM COATED, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE,

26491480

Tumour lysis syndrome, Acute kidney injury, Hepatic enzyme increased, Gamma-glutamyltransferase increased,

PIRTOBRUTINIB,

26491565

GB

Myositis, Muscle atrophy, Asthenia, Weight decreased, Dysphagia, Speech disorder, Rhabdomyolysis, Hypocalcaemia, Hyperphosphataemia, Acute kidney injury,

PANTOPRAZOLE, RAMIPRIL, METOCLOPRAMIDE, METOCLOPRAMIDE HYDROCHLORIDE, FINASTERIDE,

26491621

CA

Acute kidney injury, BK virus infection, Cystitis haemorrhagic, Cytomegalovirus infection reactivation, Encephalitis cytomegalovirus, Epstein-Barr viraemia, Generalised oedema, Lung disorder, Myelosuppression, Nephropathy toxic, Pancytopenia, Respiratory distress, Drug ineffective,

CYCLOSPORINE, CYCLOPHOSPHAMIDE FOR INJECTION, CYCLOPHOSPHAMIDE, CYCLOPHOSPHAMIDE INJECTION, SOLUTION, FOSCARNET SODIUM, GANCICLOVIR SODIUM, GANCICLOVIR, GANCICLOVIR SODIUM, GANCICLOVIR, RITUXIMAB, ANTI-THYMOCYTE GLOBULIN (RABBIT), VALGANCICLOVIR HYDROCHLORIDE, VALGANCICLOVIR, VALGANCICLOVIR HYDROCHLORIDE POWDER,, FLUDARABINE PHOSPHATE, LETERMOVIR,

26493642

Tachycardia, Tachypnoea, Thrombocytopenia, Acute kidney injury, Lactic acidosis, Pneumonia aspiration, Hypernatraemia, Pulmonary congestion, Bedridden, Regurgitation, Hypophagia, Palliative care,

LENALIDOMIDE,

26480619

EU

Infection, Acute kidney injury,

DURVALUMAB,

26480684

US

Drug reaction with eosinophilia and systemic symptoms, Odynophagia, Acute kidney injury, Acute hepatic failure, Encephalopathy,

LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE,

26481002

US

Acute kidney injury, Swollen tongue,

CISPLATIN, CISPLATIN,

26481030

EU

Haemodynamic instability, Acute kidney injury, Fall, Muscular weakness, Head injury, Hypotension, Pain, Septic shock, Hypovolaemia, Toxicity to various agents, Diabetes mellitus, Pulmonary embolism, Arteriosclerosis, Deep vein thrombosis, Intervertebral discitis, Mycobacterium ulcerans infection, Condition aggravated, Lactic acidosis, Accidental overdose, Contraindicated product administered,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, GABAPENTIN, FUROSEMIDE, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, PANTOPRAZOLE, PROPRANOLOL HYDROCHLORIDE, SPIRONOLACTONE, SEMAGLUTIDE, ORAL SEMAGLUTIDE,

26481159

EG

Blood glucose increased, Acute kidney injury, Blood urea increased, Hypotension, Ill-defined disorder, Diarrhoea, Vitamin D deficiency, Ischaemic stroke, Anal fistula, Tachycardia,

PERTUZUMAB, TRASTUZUMAB, AND HYALURONIDASE-ZZXF, PERTUZUMAB, TRASTUZUMAB, AND HYALURONIDASE-ZZXF, PERTUZUMAB, TRASTUZUMAB, AND HYALURONIDASE-ZZXF, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, BISOPROLOL FUMARATE, LOPERAMIDE HYDROCHLORIDE, LOPERAMIDE HYDROCHLORIDE AND DIMETHICONE, ERGOCALCIFEROL,

26481180

CN

Neuroleptic malignant syndrome, Respiratory distress, Acute kidney injury, Rhabdomyolysis, Ventricular tachycardia, Condition aggravated, Confusional state, Mental fatigue, Tachypnoea, Hypertonia, Serotonin syndrome, Hallucination, Seizure, Pyrexia, Muscle rigidity, Nausea, Vomiting, Tachycardia, Hyperhidrosis, Tremor, Blood pressure decreased, Intentional overdose,

SERTRALINE HYDROCHLORIDE, SERTRALINE HYDROCHLORIDE, SERTRALINE HYDROCHLORIDE, SERTRALINE HYDROCHLORIDE, QUETIAPINE, QUETIAPINE, OXAZEPAM, OXAZEPAM, OLANZAPINE,

26481186

US

Pericarditis, Encephalopathy, Drug reaction with eosinophilia and systemic symptoms, Acute kidney injury, Acute hepatic failure,

LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE,

26481597

AU

Pneumonia, Acute kidney injury, Toxicity to various agents,

ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, AMLODIPINE, AMPHETAMINE, CITALOPRAM, CITALOPRAM HYDROBROMIDE, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), HYDROMORPHONE HYDROCHLORIDE, METHADONE HYDROCHLORIDE, METHADONE, MORPHINE, OXAZEPAM, TEMAZEPAM, TRAMADOL HYDROCHLORIDE,

26481786

US

Drug reaction with eosinophilia and systemic symptoms, Encephalopathy, Acute kidney injury, Acute hepatic failure, Pericarditis,

LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE,

26482217

EU

Pancytopenia, Enteritis, Acute kidney injury,

PEMETREXED, PEMETREXED DISODIUM, PEMBROLIZUMAB, RAMIPRIL, NICARDIPINE HYDROCHLORIDE, NICARDIPINE, EZETIMIBE, LANSOPRAZOLE, FLUTICASONE FUROATE, UMECLIDINIUM BROMIDE AND VILANTEROL TRIFENATATE,