Drug Search by Year (Detail)

26871745

EU

Gastrointestinal disorder, Acute kidney injury, Lactic acidosis, Bicytopenia,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, ANASTROZOLE, ANASTROZOLE TABLETS, ANASTROZOLE, ANASTROZOLE TABLETS, ANASTROZOLE, ANASTROZOLE TABLETS, ANASTROZOLE, ANASTROZOLE TABLETS, SPIRONOLACTONE, SPIRONOLACTONE, SPIRONOLACTONE, SPIRONOLACTONE, RIBOCICLIB, RIBOCICLIB, RIBOCICLIB, RIBOCICLIB, DENOSUMAB, DENOSUMAB, DENOSUMAB, DENOSUMAB, SIMVASTATIN, SIMVASTATIN, SIMVASTATIN, SIMVASTATIN,

26871963

US

Acute kidney injury, Headache,

LEVOKETOCONAZOLE,

26872245

EU

Acute kidney injury, Drug interaction, Drug ineffective,

MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, PREDNISONE, ISAVUCONAZONIUM SULFATE, ISAVUCONAZONIUM SULFATE, ISAVUCONAZONIUM SULFATE,

26862683

Hypokalaemia, Acute kidney injury, Disease progression, Abdominal pain upper, Constipation, Diarrhoea, Fatigue, Nausea, Vomiting,

TRASTUZUMAB, FAM-TRASTUZUMAB DERUXTECAN-NXKI,

26862750

US

Acute kidney injury, Diarrhoea, Dehydration,

ORAL SEMAGLUTIDE,

26862806

EU

Pyuria, Incontinence, Acute kidney injury,

SILODOSIN, PITOLISANT HYDROCHLORIDE, PITOLISANT HYDROCHLORIDE, PITOLISANT HYDROCHLORIDE, PITOLISANT HYDROCHLORIDE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, DULOXETINE HYDROCHLORIDE, DULOXETINE, SPIRONOLACTONE, SODIUM CHLORIDE, SODIUM CHLORIDE TABLET, SODIUM CHLORIDE TABLETS, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, IRBESARTAN, EMPAGLIFLOZIN, PANTOPRAZOLE, ESCITALOPRAM OXALATE, ESCITALOPRAM,

26862926

Cholestasis, Acute hepatic failure, Hepatorenal syndrome, Cholangitis acute, Acute kidney injury, Cryptosporidiosis infection,

MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, PREDNISONE, RITUXIMAB,

26863177

US

Acute kidney injury, Dehydration, Pulmonary arterial hypertension, Nausea, Dyspepsia, Diarrhoea, Vomiting, Fatigue, Drug interaction, Positive airway pressure therapy,

ORAL SEMAGLUTIDE, TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, TREPROSTINIL, POTASSIUM CHLORIDE, POTASSIUM CHLORIDE EXTENDED-RELEASE, POTASSIUM CHLORIDE, DEXTROSE MONOHYDRATE, POTASSIUM CHLORIDE ORAL, LISINOPRIL AND HYDROCHLOROTHIAZIDE, LISINOPRIL AND HYDROCHLOROTHIAZIDE TABLETS, GABAPENTIN, SILDENAFIL CITRATE, SILDENAFIL, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, SPIRONOLACTONE, AMBRISENTAN, COLESEVELAM HYDROCHLORIDE, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, FUROSEMIDE, VALACYCLOVIR, VALACYCLOVIR HYDROCHLORIDE,

26863199

AU

Acute kidney injury, Hypokalaemia, Disease progression, Abdominal pain upper, Constipation, Diarrhoea, Fatigue, Nausea, Vomiting,

TRASTUZUMAB, FAM-TRASTUZUMAB DERUXTECAN-NXKI,

26863249

Acute kidney injury,

FUROSEMIDE, EMPAGLIFLOZIN,

26863394

GE

Acute kidney injury, Drug reaction with eosinophilia and systemic symptoms, Cholestatic liver injury,

26863695

US

Drug reaction with eosinophilia and systemic symptoms, Acute kidney injury, Hypotension,

CARBAMAZEPINE, CARBAMAZEPINE,

26864000

Renal tubular necrosis, Acute kidney injury,

IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN TABLET, FILM COATED, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE,

26864025

EU

Faecaloma, Large intestinal obstruction, Syncope, Colitis ischaemic, Hypoxia, Respiratory failure, Acute kidney injury, Lactic acidosis, Megacolon, Shock, Anuria, Myocardial infarction, Hepatic failure, Hypoglycaemia, Fall, Contusion, Dyspnoea, Somnolence, Hypotension, Dehydration, Subileus, Hypercalcaemia, Hypercapnia, Mesenteritis, General physical health deterioration,

UMECLIDINIUM, ALBUTEROL SULFATE, ALBUTEROL, ESOMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM, ROSUVASTATIN, QUETIAPINE FUMARATE, QUETIAPINE, OXAZEPAM, QUETIAPINE FUMARATE, QUETIAPINE, MINERAL OIL,

26864069

US

Intentional overdose, Lactic acidosis, Acute kidney injury, Hypotension, Metabolic acidosis, Upper gastrointestinal haemorrhage,

IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN TABLET, FILM COATED, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE,

26864214

EU

Crystal nephropathy, Acute kidney injury,

RAMIPRIL, AMLODIPINE,

26864504

Lactic acidosis, Hypovolaemic shock, Acute kidney injury, Hypotension, Metabolic acidosis, Respiratory acidosis, Starvation ketoacidosis,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG,

26864576

EU

Diarrhoea, Acute kidney injury, Blood creatinine increased,

PATIROMER,

26864799

Tachycardia, Hypotension, Diarrhoea, Mucosal inflammation, Encephalopathy, Hypophagia, Dehydration, Acute kidney injury, Accidental overdose, Hypernatraemia, Drug interaction, Inappropriate schedule of product administration, Myelosuppression, Toxicity to various agents,

METHOTREXATE, METHOTREXATE SODIUM, SULFAMETHOXAZOLE AND TRIMETHOPRIM, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION,

26865009

US

Toxicity to various agents, Dehydration, Cachexia, Encephalopathy, Hypophagia, Acute kidney injury, Drug clearance decreased, Stomatitis, Cardiac murmur, Wound, Overdose,

METHOTREXATE, METHOTREXATE SODIUM, PREDNISONE,

26865081

US

Lactic acidosis, Hypoglycaemia, Acute kidney injury, Renal tubular necrosis, Hyperkalaemia, Drug interaction, Toxicity to various agents, Metabolic acidosis,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, TIRZEPATIDE, TIRZEPATIDE, LOSARTAN, CLONIDINE, DAPAGLIFLOZIN, INSULIN GLARGINE-YFGN, INSULIN GLARGINE, DEXTROSE MONOHYDRATE, DEXTROSE,

26865118

EU

Dermo-hypodermitis, Infection, Acute kidney injury,

IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN TABLET, FILM COATED, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE,

26865167

US

Mucosal inflammation, Acute kidney injury, Streptococcal bacteraemia, Streptococcal endocarditis,

METHOTREXATE, METHOTREXATE SODIUM, GANCICLOVIR SODIUM, GANCICLOVIR,

26865442

US

Bone marrow failure, Folate deficiency, Drug interaction, Acute kidney injury, Arrhythmia, Supraventricular tachycardia, Mucocutaneous candidiasis, Candida infection, Encephalopathy, Septic shock, Cerebral infarction, Loss of consciousness,

METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, SULFAMETHOXAZOLE AND TRIMETHOPRIM, SULFAMETHOXAZOLE AND TRIMETHOPRIM, SULFAMETHOXAZOLE AND TRIMETHOPRIM, SULFAMETHOXAZOLE AND TRIMETHOPRIM, ABATACEPT, ABATACEPT, ABATACEPT, ABATACEPT,

26865444

US

Tachycardia, Hypotension, Myelosuppression, Stomatitis, Diarrhoea, Encephalopathy, Hypophagia, Dehydration, Acute kidney injury, Hypernatraemia, Inappropriate schedule of product administration, Accidental overdose, Drug interaction, Toxicity to various agents, Drug clearance decreased,

SULFAMETHOXAZOLE AND TRIMETHOPRIM, PREDNISONE,

26865577

Hyperinsulinaemia, Acute kidney injury, Suicide attempt, Toxicity to various agents, Circulatory collapse, Hypoglycaemia, Lactic acidosis, Intentional overdose,

INSULIN GLARGINE,

26865713

RU

Disease progression, Acute kidney injury, Cytopenia,

RITUXIMAB, OBINUTUZUMAB, CYCLOPHOSPHAMIDE FOR INJECTION, CYCLOPHOSPHAMIDE, CYCLOPHOSPHAMIDE INJECTION, SOLUTION, DOXORUBICIN, PREDNISONE, DEXAMETHASONE, DEXAMETHASONE 1.5 MG, CYTARABINE, CISPLATIN,

26865714

US

Lactic acidosis, Hyperkalaemia, Acute kidney injury, Renal tubular necrosis, Metabolic acidosis, Hypoglycaemia, Drug interaction, Toxicity to various agents,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, LISINOPRIL, ROSUVASTATIN,

26865883

EU

Multiple organ dysfunction syndrome, Toxicity to various agents, Thrombotic thrombocytopenic purpura, Disseminated intravascular coagulation, Toxicity to various agents, Alcohol poisoning, Suicide attempt, Drug interaction, Sopor, Hallucination, visual, Tachycardia, Melaena, Restlessness, Respiratory failure, Pleural effusion, Pancreatitis, Metabolic acidosis, Malaise, Blood lactic acid increased, Colitis ischaemic, Hypotension, Rash, Disorientation, Dyspnoea, Acute kidney injury, Abdominal pain, Somnolence, Intentional overdose,

ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ALCOHOL, ETHYL ALCOHOL, ISOPROPYL ALCOHOL, ALCOHOL, ETHYL ALCOHOL, ISOPROPYL ALCOHOL, ALCOHOL, ETHYL ALCOHOL, ISOPROPYL ALCOHOL, ALCOHOL, ETHYL ALCOHOL, ISOPROPYL ALCOHOL,

26866032

Acute kidney injury, Polyuria, Alkalosis hypochloraemic,

BUMETANIDE, BUMETANIDE, SPIRONOLACTONE, SPIRONOLACTONE, SPIRONOLACTONE, EMPAGLIFLOZIN, EMPAGLIFLOZIN, POTASSIUM CHLORIDE, MELATONIN, GABAPENTIN, QUETIAPINE, SODIUM CHLORIDE, SODIUM CHLORIDE TABLET, SODIUM CHLORIDE TABLETS, SODIUM CHLORIDE, SODIUM CHLORIDE TABLET, SODIUM CHLORIDE TABLETS, ACETAMINOPHEN, GUAIFENESIN, AND PHENYLEPHRINE HYDROCHLORIDE, ACETAMINOPHEN, RIVAROXABAN,

26866065

EU

Hyperkalaemia, Acute kidney injury, Electrocardiogram T wave amplitude increased, Metabolic acidosis, Drug interaction,

SPIRONOLACTONE, CILOSTAZOL,

26866150

EU

Neurotoxicity, Drug interaction, Speech disorder, Acute kidney injury, Hallucination, visual, Coordination abnormal, Balance disorder, Headache,

CYCLOSPORINE, MYCOPHENOLIC ACID, MYCOPHENILIC ACID, ACYCLOVIR, ACYCLOVIR,

26866351

EU

Suicide attempt, Intentional overdose, Somnolence, Shock, Hypoglycaemia, Lactic acidosis, Acute kidney injury,

26866619

EU

Acute kidney injury, Hyperkalaemia, Nodal rhythm, Concomitant disease aggravated,

SACUBITRIL AND VALSARTAN, TORSEMIDE, AMIODARONE HYDROCHLORIDE,

26866922

US

Pancreatitis acute, Hypertriglyceridaemia, Diabetic ketoacidosis, Acute kidney injury, Pancreatitis necrotising, Pancreatic pseudocyst, Product use issue,

ESTRADIOL, ESTRADIOL GEL 0.1%, ESTRADIOL TRANSDERMAL, ESTRADIOL,,

26867023

RU

Acute kidney injury,

CYCLOSPORINE, CYCLOSPORINE, CYCLOSPORINE, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, PREDNISOLONE, PREDNISOLONE ORAL, PREDNISOLONE ORAL SOLUTION, METHYLPREDNISOLONE,

26867202

CH

Acute kidney injury,

PEMBROLIZUMAB, PEMETREXED, PEMETREXED DISODIUM, CARBOPLATIN,

26867315

EU

Acute kidney injury, Hyperuricaemia, Pancytopenia, Influenza, Hepatitis E, Pneumonia, Lymphoma, Hypogammaglobulinaemia, Febrile neutropenia, Mantle cell lymphoma, Malignant neoplasm progression, Renal failure, Aortic valve incompetence, Mitral valve incompetence, Carotid arteriosclerosis, Neuropathy peripheral, Type 2 diabetes mellitus, Diabetic neuropathy, Osteochondrosis, Lentigo maligna, Basal cell carcinoma, Transient ischaemic attack, Diarrhoea, Cardiac hypertrophy, Lymphopenia, Genital herpes, Oral candidiasis, Abdominal lymphadenopathy, Hernia, Goitre, Hypertension, Lipid metabolism disorder, Prostatomegaly, Prostatitis, Fatigue, Spinal osteoarthritis, Spinal pain, Intervertebral disc protrusion, Seasonal allergy, Nasal polyps, Dysplastic naevus, Adjustment disorder with depressed mood, Conjunctivitis, Herpes simplex, Asthenia, Dyspnoea exertional, Gastrointestinal disorder, Pain in extremity, Musculoskeletal disorder, Road traffic accident, Spinal column injury, Arthropathy, Headache, Sleep disorder,

DOXORUBICIN HYDROCHLORIDE, DOXORUBICIN, CYCLOPHOSPHAMIDE FOR INJECTION, CYCLOPHOSPHAMIDE, CYCLOPHOSPHAMIDE INJECTION, SOLUTION, PREDNISONE, VINCRISTINE SULFATE, BENDAMUSTINE HCL, CYTARABINE, CISPLATIN, DEXAMETHASONE, DEXAMETHASONE 1.5 MG, CARMUSTINE, CYTARABINE, MELPHALAN HYDROCHLORIDE, MELPHALAN, ETOPOSIDE, IBRUTINIB, BISOPROLOL FUMARATE, LEVOTHYROXINE SODIUM, LEVOTHYROXINE SODIUM ANHYDROUS, ZINC, ZINC GLUCONATE, ZINC CHLORIDE, SELENIUM, PANCRELIPASE,

26867640

US

Rhabdomyolysis, Hypertransaminasaemia, Acute kidney injury, Drug interaction,

RANOLAZINE,

26867762

JP

Death, Portal vein thrombosis, Hepatocellular carcinoma, Acute kidney injury, Hypoalbuminaemia, Oliguria, Postoperative thrombosis, Off label use,

BEVACIZUMAB, ATEZOLIZUMAB,

26857356

Acute kidney injury, Drug interaction, Toxicity to various agents, Drug level increased, Lactic acidosis,

METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, CLONIDINE, DAPAGLIFLOZIN, DEXTROSE MONOHYDRATE, DEXTROSE, DULAGLUTIDE, INSULIN GLARGINE-YFGN, INSULIN GLARGINE, LOSARTAN, TIRZEPATIDE,

26857357

Acute kidney injury, Toxicity to various agents, Drug interaction, Lactic acidosis, Drug level increased,

METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, LISINOPRIL, ROSUVASTATIN,

26857359

Acute kidney injury, Toxicity to various agents, Drug interaction, Lactic acidosis, Drug level increased,

METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, AMLODIPINE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, HYDROCHLOROTHIAZIDE, LISINOPRIL, NOREPINEPHRINE (BITARTRATE), NOREPINEPHRINE, NOREPINEPHRINE BITARTRATE, PRASUGREL, SODIUM BICARBONATE, SODIUM BICARBONATE, INJECTION, SODIUM BICARBONATE INJECTION,, TOCILIZUMAB, VASOPRESSIN,

26857363

Acute kidney injury, Toxicity to various agents, Drug interaction, Lactic acidosis, Drug level increased,

METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, GLYBURIDE, LINAGLIPTIN, LISINOPRIL,

26857433

US

Drug interaction, Lactic acidosis, Hypoglycaemia, Acute kidney injury, Metabolic acidosis, Hyperkalaemia, Acetonaemia, Diabetic ketoacidosis, Oliguria, Myocardial ischaemia,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, INSULIN GLARGINE-YFGN, INSULIN GLARGINE, LISINOPRIL, HYDROCHLOROTHIAZIDE, AMLODIPINE, ATORVASTATIN CALCIUM, ATORVASTATIN CALCIUM, FILM COATED, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, PRASUGREL, TOCILIZUMAB,

26857543

US

Drug interaction, Lactic acidosis, Hypoglycaemia, Metabolic acidosis, Acute kidney injury, Hyperkalaemia, Oliguria,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, INSULIN ASPART, LISINOPRIL, ROSUVASTATIN,

26857678

Renal tubular necrosis, Acute kidney injury, Drug interaction,

AMLODIPINE, VALSARTAN, VALSARTAN ORAL, EMPAGLIFLOZIN,

26857733

Lactic acidosis, Dehydration, Acute kidney injury, Toxicity to various agents,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, GLIMEPIRIDE, INSULIN GLARGINE-YFGN, INSULIN GLARGINE, TERAZOSIN, TERAZOSIN HYDROCHLORIDE,

26857935

Acute kidney injury, Chronic kidney disease,

MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, ENTECAVIR, ENTECAVIR ANHYDROUS, PREDNISONE, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES,

26857992

EU

Hypotension, Acute kidney injury, Dehydration, Diarrhoea, Epilepsy, Medical device site injury, Pathogen resistance, Mental impairment, Stoma site erythema, Stoma site discharge, Atrophy, Cerebral small vessel ischaemic disease, Adverse drug reaction, Akinesia, Blood urea increased, Blood creatinine increased, Glomerular filtration rate decreased, Depressed level of consciousness, Fatigue, Somnolence, Neck pain, Back pain, Generalised tonic-clonic seizure, Infection, Stoma site infection,

ESOMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM, LEVETIRACETAM, LEVETIRACETAM IN SODIUM CHLORIDE, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, LEVETIRACETAM, LEVETIRACETAM IN SODIUM CHLORIDE, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, QUETIAPINE, QUETIAPINE, SERTRALINE, SERTRALINE, SUCRALFATE, SUCRALFATE ORAL SUSPENSION, SUCRALFATE ORAL,

26858222

IN

Acute kidney injury, Encephalopathy, Azotaemia, Hyponatraemia, Fall,

FLUCONAZOLE, FLUCONAZOLE, CEFTRIAXONE, CEFTRIAXONE SODIUM, CEFTRIAXONE, CEFTRIAXONE SODIUM,

26858246

US

Neutropenia, Pyrexia, Oropharyngeal pain, Diarrhoea, Off label use, Nausea, Systemic inflammatory response syndrome, Lupus nephritis, Proteinuria, Vomiting, Acute kidney injury, Blood creatinine increased, Presyncope, Dizziness postural, Autonomic nervous system imbalance, Electrolyte imbalance, Fatigue,

MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL HYDROCHLORIDE, VOCLOSPORIN, BELIMUMAB,

26858276

CH

Enterocolitis, Myositis, Acute kidney injury, Hepatic cytolysis, Rash erythematous,

ENFORTUMAB VEDOTIN, ENFORTUMAB VEDOTIN, PEMBROLIZUMAB, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, ALLOPURINOL,

26858356

EU

Thrombocytopenia, Acute kidney injury, Hyperkalaemia, Hyponatraemia, Neutropenia,

CISPLATIN, GEMCITABINE HYDROCHLORIDE, GEMCITABINE, DURVALUMAB, INSULIN GLARGINE-YFGN, INSULIN GLARGINE, BISOPROLOL FUMARATE, AMLODIPINE, MORPHINE,

26858491

EU

Pancytopenia, Neutropenia, Polyuria, Diabetes insipidus, Acute kidney injury, Anaemia, Thrombocytopenia, Leukopenia,

TEMOZOLOMIDE, TEMOZOLOMIDE, TEMOZOLOMIDE, TEMOZOLOMIDE, TEMOZOLOMIDE, LEVETIRACETAM, SEVELAMER CARBONATE,

26858535

US

Hypertransaminasaemia, Rhabdomyolysis, Acute kidney injury, Drug interaction,

RANOLAZINE,

26858562

EU

Acute kidney injury, Thrombocytopenia,

TEMOZOLOMIDE, CHLORPROMAZINE,

26858715

US

Bone marrow failure, Mucosal inflammation, Oral pain, Hypophagia, Cerebral infarction, Folate deficiency, Electrolyte imbalance, Encephalopathy, Acute kidney injury, Supraventricular tachycardia, Arrhythmia, Dependence on respirator, Loss of consciousness, Myelosuppression, Confusional state, Pancytopenia, Fatigue, Septic shock, Candida infection, Mucocutaneous candidiasis,

METHOTREXATE, METHOTREXATE SODIUM, SULFAMETHOXAZOLE AND TRIMETHOPRIM, ABATACEPT,

26858745

JP

Acute kidney injury, Dialysis, Anuria, Blood creatinine increased,

EMPAGLIFLOZIN,

26858812

US

Acute kidney injury, Renal tubular necrosis, Drug interaction, Fall,

VALSARTAN, VALSARTAN ORAL, AMLODIPINE, EMPAGLIFLOZIN,

26858870

CO

Acute kidney injury, Seizure, Coma, Poisoning,

ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG,

26858908

CO

Acute kidney injury, Seizure, Poisoning,

ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG,

26859109

US

Acute kidney injury, Asterixis, Toxicity to various agents, Hypercapnia,

GABAPENTIN,

26859121

US

Candida infection, Mucosal inflammation, Septic shock, Pancytopenia, Toxicity to various agents, Encephalopathy, Loss of consciousness, Bone marrow failure, Acute kidney injury, Drug interaction, Folate deficiency,

METHOTREXATE, METHOTREXATE SODIUM, SULFAMETHOXAZOLE AND TRIMETHOPRIM, ABATACEPT,

26859148

EU

Gastrointestinal disorder, Acute kidney injury, Lactic acidosis, Bicytopenia,

DENOSUMAB, ANASTROZOLE, ANASTROZOLE TABLETS, RIBOCICLIB, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, SPIRONOLACTONE, SIMVASTATIN,

26859178

TW

Hyperammonaemia, Acute kidney injury, Hyperkalaemia, Hepatitis, Metabolic acidosis, Euglycaemic diabetic ketoacidosis, Hypophosphataemia, Asthenia, Refeeding syndrome, Leukocytosis, Lipase increased, Mental status changes, Lactic acidosis,

GLIMEPIRIDE, VALSARTAN, VALSARTAN ORAL, ROSUVASTATIN,

26859179

EU

Acute kidney injury, Lactic acidosis, Gastrointestinal disorder, Bicytopenia,

ANASTROZOLE, ANASTROZOLE TABLETS, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, SPIRONOLACTONE, RIBOCICLIB, DENOSUMAB, SIMVASTATIN,

26859381

EU

Hypokalaemia, Diarrhoea, Acute kidney injury, Weight decreased,

BUDESONIDE, ROSUVASTATIN, DABIGATRAN ETEXILATE,

26859478

MX

Adverse drug reaction, Acute kidney injury, Infusion related reaction, Off label use, Serum sickness,

OBINUTUZUMAB, RITUXIMAB, CYCLOPHOSPHAMIDE FOR INJECTION, CYCLOPHOSPHAMIDE, CYCLOPHOSPHAMIDE INJECTION, SOLUTION,

26859531

US

Hyperthyroidism, Thyrotoxic crisis, Encephalopathy, Acute kidney injury, Cardiogenic shock, Cardiac failure, Liver injury, Multiple organ dysfunction syndrome,

26859538

EU

Lactic acidosis, Acute kidney injury, Diarrhoea, Somnolence, Product prescribing error,

FUROSEMIDE, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, RAMIPRIL, GABAPENTIN, TRAMADOL HYDROCHLORIDE, PANTOPRAZOLE, PAROXETINE HYDROCHLORIDE, BISOPROLOL FUMARATE, RISPERIDONE, OXAZEPAM, POLYETHYLENE GLYCOL 3350, POLYETHYLENE GLYCOL (3350), POLYETHYLENE GLYCOL 400, INSTALAX POLYETHYLENE GLYCOL 3350, TAMSULOSIN HYDROCHLORIDE, RISEDRONATE SODIUM,

26859672

US

Crystal nephropathy, Toxicity to various agents, Acute kidney injury, Drug ineffective,

METHOTREXATE, METHOTREXATE SODIUM, DOXORUBICIN, POLATUZUMAB VEDOTIN, RITUXIMAB, CYCLOPHOSPHAMIDE FOR INJECTION, CYCLOPHOSPHAMIDE, CYCLOPHOSPHAMIDE INJECTION, SOLUTION, PREDNISONE, CYTARABINE, THIOTEPA,

26860466

US

Acute hepatic failure, Brain oedema, Respiratory failure, Shock, Acute kidney injury, Atrial fibrillation, Gastrointestinal haemorrhage, Thrombocytopenia, Coagulopathy,

ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER,

26860674

EU

Acute kidney injury, Ascites, Interstitial lung disease, Gastritis hypertrophic, Chronic kidney disease, Hepatomegaly, Pleural effusion, Diverticulum intestinal, Nephropathy,

TICAGRELOR, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, EZETIMIBE, METOPROLOL TARTRATE, METOROPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE, METOROPROLOL TARTRATE, METOPROLOL, RAMIPRIL, PREDNISONE, PANTOPRAZOLE, ERGOCALCIFEROL, FUROSEMIDE, CLOPIDOGREL, CLOPIDOGREL BISULFATE, ROSUVASTATIN, FAMOTIDINE,

26860752

US

Delirium, Tremor, Hyperkalaemia, Acute kidney injury,

SULFAMETHOXAZOLE AND TRIMETHOPRIM,

26860976

BY

Pneumonia, Productive cough, Dyspnoea at rest, Oxygen saturation decreased, Pyrexia, Influenza, Respiratory failure, Acute kidney injury, Acute hepatic failure, Bronchial obstruction, Bronchopulmonary aspergillosis,

CYCLOSPORINE, CYCLOSPORINE, METHYLPREDNISOLONE,

26861060

IN

Pleural effusion, Blood glucose increased, Acute kidney injury,

26861412

EU

Acute kidney injury, Lactic acidosis, Spinal cord haematoma, Hypoglycaemia, Rhabdomyolysis,

METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, DAPAGLIFLOZIN,

26861568

Acute kidney injury,

SILDENAFIL CITRATE, SILDENAFIL, SILDENAFIL POWDER,, EPOETIN ALFA-EPBX,

26861585

EU

Aggression, Delirium, Acute kidney injury,

TACROLIMUS,

26861705

EU

Hyperlactacidaemia, Acute kidney injury, Bicytopenia, Toxicity to various agents, Metabolic acidosis, Tachypnoea, Abdominal tenderness, Diarrhoea, Abdominal pain, Nausea, Gastrointestinal disorder, Suspected off label use,

LINEZOLID, LINEZOLID, LINEZOLID,

26861925

IN

Abdominal sepsis, Acute kidney injury, Kidney infection, Congenital cystic kidney disease, Haemorrhagic hepatic cyst, Pneumonia klebsiella, Toxicity to various agents, Kidney enlargement, Constipation, Urinary tract infection, Blood creatinine increased, Electrolyte imbalance, BK virus infection, Abdominal distension, Abdominal pain, Hypoalbuminaemia, Product prescribing issue, Off label use,

MYCOPHENOLIC ACID, MYCOPHENOLIC ACID, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES,

26862189

TH

Acute kidney injury, Lactic acidosis,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, ENALAPRIL, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, SIMVASTATIN, PIOGLITAZONE,

26862265

OM

Proteinuria, Acute kidney injury,

ATEZOLIZUMAB, BEVACIZUMAB,

26865484

Cytokine release syndrome, Immune effector cell-associated neurotoxicity syndrome, Acute kidney injury, Hypertransaminasaemia, Stress cardiomyopathy, Cardiogenic shock, Hyponatraemia, Cytomegalovirus viraemia, Seizure, Human herpesvirus 6 infection, Presyncope, Orthostatic hypotension, Haemophagocytic lymphohistiocytosis,

AXICABTAGENE CILOLEUCEL,

26852330

JP

Acute kidney injury, Blood urea increased, Blood creatinine increased, Hyperthermia malignant, End-tidal CO2 increased, Body temperature increased, Hyperhidrosis, PCO2 increased, Metabolic acidosis, Respiratory acidosis, Creatine kinase increased,

DESFLURANE, ROCURONIUM BROMIDE, ROCURONIUM, ROCURONIUM BROMIDE, ROCURONIUM, FENTANYL, PROPOFOL,

26852339

Acute kidney injury,

FUROSEMIDE, EMPAGLIFLOZIN,

26852469

Acute kidney injury, Renal tubular necrosis, Drug interaction,

AMLODIPINE, VALSARTAN, VALSARTAN ORAL, EMPAGLIFLOZIN,

26852566

Cardiac failure congestive, Acute kidney injury, Metabolic acidosis, Lactic acidosis, Cardiogenic shock, Pulseless electrical activity, Bradycardia, Diarrhoea,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, SITAGLIPTIN,

26852775

Lactic acidosis, Ketoacidosis, Acute kidney injury, Hypovolaemia,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG,

26852916

EU

Nervous system disorder, Acute kidney injury, Overdose, Wrong product administered,

ACYCLOVIR, VALACYCLOVIR HYDROCHLORIDE, VALACYCLOVIR,

26853292

EU

Acute kidney injury, Condition aggravated,

FUROSEMIDE, SPIRONOLACTONE,

26853320

US

Diabetic ketoacidosis, Acute kidney injury, Pancreatitis necrotising, Pancreatic pseudocyst, Pancreatitis acute, Hypertriglyceridaemia,

ESTRADIOL, ESTRADIOL GEL 0.1%, ESTRADIOL TRANSDERMAL, ESTRADIOL,,

26853590

US

Lactic acidosis, Drug interaction, Hypoglycaemia, Acute kidney injury, Drug level increased, Gastrointestinal disorder, Hyperkalaemia,

METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, LISINOPRIL, LINAGLIPTIN, GLYBURIDE,

26853643

US

Lactic acidosis, Drug interaction, Gastrointestinal disorder, Hypoglycaemia, Acute kidney injury, Hyperkalaemia, Drug level increased, Hypotension, Renal tubular necrosis,

METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, TIRZEPATIDE, CLONIDINE, DAPAGLIFLOZIN, INSULIN GLARGINE-YFGN, INSULIN GLARGINE, LOSARTAN,

26853673

EU

Acute kidney injury, Hyponatraemia, Hypokalaemia,

FUROSEMIDE, RAMIPRIL, HYDROCHLOROTHIAZIDE,

26853800

US

Lactic acidosis, Drug interaction, Hypoglycaemia, Acute kidney injury, Drug level increased, Gastrointestinal disorder, Hyperkalaemia, Diabetic ketoacidosis,

METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, LISINOPRIL, INSULIN GLARGINE-YFGN, INSULIN GLARGINE, HYDROCHLOROTHIAZIDE, AMLODIPINE, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, PRASUGREL, TOCILIZUMAB,

26853852

US

Pancytopenia, Mucosal inflammation, Septic shock, Candida infection, Mucocutaneous candidiasis, Bone marrow failure, Folate deficiency, Electrolyte imbalance, Acute kidney injury, Arrhythmia, Supraventricular tachycardia, Haematoma, Fall, Encephalopathy, Drug interaction, Fungaemia, Cerebral infarction,

METHOTREXATE, METHOTREXATE SODIUM, SULFAMETHOXAZOLE AND TRIMETHOPRIM, ABATACEPT,

26853859

US

Lactic acidosis, Drug interaction, Hypoglycaemia, Acute kidney injury, Drug level increased, Gastrointestinal disorder, Hyperkalaemia,

METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, LISINOPRIL, INSULIN ASPART, ROSUVASTATIN,

26853901

US

Lethargy, Labile blood pressure, Acute kidney injury, Lactic acidosis, Drug interaction, Metabolic acidosis, Nausea, Vomiting, Hypophagia, Hypoglycaemia, Drug level increased,

METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, LINAGLIPTIN, GLYBURIDE, LISINOPRIL,