Drug Search by Year (Detail)

26840480

EU

Gastroenteritis, Acute kidney injury,

METHOTREXATE, METHOTREXATE SODIUM, ADALIMUMAB-AATY, PREDNISONE,

26840718

CA

Myocarditis, Schizophrenia, Antipsychotic drug level above therapeutic, Mental status changes, Seizure, Acute kidney injury, Sedation, Constipation, Neutropenia, Orthostatic hypotension, Self-medication, Treatment noncompliance, Drug ineffective, Product dose omission issue,

OLANZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, CLOZAPINE, VALPROIC ACID, VALPROIC ACID, VALPROIC ACID, VALPROIC ACID, VALPROIC ACID, VALPROIC ACID, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, CLOPIDOGREL, CLOPIDOGREL BISULFATE, EDOXABAN TOSYLATE, LATANOPROST, LORAZEPAM, PALIPERIDONE, PALIPERIDONE, PALIPERIDONE, RISPERIDONE, ERGOCALCIFEROL,

26840722

EU

Acute kidney injury, Nausea, Diarrhoea,

GOSERELIN, GOSERELIN, FULVESTRANT, INAVOLISIB, INAVOLISIB, INAVOLISIB, INAVOLISIB, PALBOCICLIB, PALBOCICLIB, PALBOCICLIB, PALBOCICLIB,

26840917

US

Gastroenteritis cryptosporidial, Acute kidney injury, Renal tubular necrosis, Encephalopathy, Metabolic acidosis,

BUDESONIDE, SULFASALAZINE, VEDOLIZUMAB, IPILIMUMAB, NIVOLUMAB, PEMBROLIZUMAB,

26841490

US

Toxicity to various agents, Lactic acidosis, Acute kidney injury, Hypoglycaemia, Mental status changes, Constipation, Hypophagia, Dehydration,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, GLIMEPIRIDE, INSULIN GLARGINE-YFGN, INSULIN GLARGINE, LISINOPRIL AND HYDROCHLOROTHIAZIDE, LISINOPRIL AND HYDROCHLOROTHIAZIDE TABLETS, ATORVASTATIN CALCIUM, ATORVASTATIN CALCIUM, FILM COATED, TERAZOSIN, TERAZOSIN HYDROCHLORIDE,

26841502

EU

Acute kidney injury,

SPIRONOLACTONE, SPIRONOLACTONE, SPIRONOLACTONE, BUMETANIDE, BUMETANIDE, HYDROCHLOROTHIAZIDE, HYDROCHLOROTHIAZIDE, HYDROCHLOROTHIAZIDE, FUROSEMIDE, FUROSEMIDE, FUROSEMIDE, FUROSEMIDE, FUROSEMIDE, VANCOMYCIN HYDROCHLORIDE, VANCOMYCIN, VANCOMYCIN HYDROCHLORIDE, VANCOMYCIN, VANCOMYCIN HYDROCHLORIDE, VANCOMYCIN, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, BISOPROLOL FUMARATE, EPLERENONE, MEROPENEM, LANSOPRAZOLE, PROPOFOL, DAPAGLIFLOZIN, DOBUTAMINE HYDROCHLORIDE, LIDOCAINE, LIDOCAINE HYDROCHLORIDE, BURN RELIEF, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE, LIDICAINE, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE, LIDOCAINE 4%, LIDOCAINE, MENTHOL, WARFARIN, RIVAROXABAN, POTASSIUM CHLORIDE, POTASSIUM CHLORIDE EXTENDED-RELEASE, POTASSIUM CHLORIDE, DEXTROSE MONOHYDRATE, POTASSIUM CHLORIDE ORAL, MAGNESIUM SULFATE, MAGNESIUM SULFATE HEPTAHYDRATE, MAGNESIUM SULFATE IN WATER FOR, DEXMEDETOMIDINE HYDROCHLORIDE IN SODIUM CHLORIDE, DEXMEDETOMIDINE HYDROCHLORIDE, DEXMEDETOMIDINE HYDROCHLORIDE IN 0.9% SODIUM CHLORIDE, HEPARIN SODIUM, SACUBITRIL AND VALSARTAN,

26841515

EU

Shock, Gastrointestinal obstruction, Acute kidney injury, Febrile neutropenia,

CISPLATIN, PACLITAXEL, PACLITAXEL (AIBUMIN-BOUND), ONDANSETRON HYDROCHLORIDE, ONDANSETRON, ONDANSETRON TABLETS, IFOSFAMIDE, IFOSFAMIDE FOR INJECTION, METHYLPREDNISOLONE, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, OLANZAPINE, DEXAMETHASONE, DEXAMETHASONE 1.5 MG, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, ENOXAPARIN SODIUM, EPOETIN ALFA-EPBX, PEGFILGRASTIM, MESNA, MESNA INJECTION,

26841614

EU

Hyperkalaemia, Pneumonia pneumococcal, Septic shock, Respiratory distress, Altered state of consciousness, Sepsis, Acute kidney injury, Dyspnoea, Chest pain, Cough, Sputum purulent, Livedo reticularis, Peripheral coldness, Chills, Pyrexia,

VALSARTAN, VALSARTAN ORAL, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, BISOPROLOL FUMARATE, DAPAGLIFLOZIN, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG,

26841904

CA

Clostridium difficile colitis, Electrolyte imbalance, Mouth ulceration, Acute kidney injury,

ISAVUCONAZONIUM SULFATE, ISAVUCONAZONIUM SULFATE, ATOVAQUONE, ATOVAQUONE ORAL SUSPENSION, DEFERASIROX, LIDOCAINE, LIDOCAINE HYDROCHLORIDE, BURN RELIEF, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE, LIDICAINE, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE, LIDOCAINE 4%, LIDOCAINE, MENTHOL, NYSTATIN, NYSTATIN OINTMENT, NYSTATIN CREAM, SODIUM CHLORIDE, SODIUM CHLORIDE TABLET, SODIUM CHLORIDE TABLETS, PANTOPRAZOLE, POSACONAZOLE, POSACONAZOLE DELAYED-RELEASE, SODIUM CHLORIDE, SODIUM CHLORIDE TABLET, SODIUM CHLORIDE TABLETS, VALACYCLOVIR HYDROCHLORIDE,

26841952

Pancreatitis, Azotaemia, Acute kidney injury, Hyponatraemia, Metabolic acidosis,

AMLODIPINE, AMLODIPINE, LOSARTAN, LOSARTAN,

26842127

US

Metabolic acidosis, Azotaemia, Azotaemia, Pancreatitis acute, Acute kidney injury, Hyponatraemia,

LOSARTAN, LOSARTAN, AMLODIPINE, AMLODIPINE,

26842195

Acute kidney injury, Primary progressive multiple sclerosis, Condition aggravated,

LOSARTAN, GABAPENTIN,

26842261

EU

Hypokalaemia, Toxicity to various agents, Metabolic alkalosis, Febrile neutropenia, Acute kidney injury, Pleural effusion, Overdose, Product use in unapproved indication, Product use issue,

METHOTREXATE, METHOTREXATE SODIUM, METHOTREXATE, METHOTREXATE SODIUM, RITUXIMAB, LEVETIRACETAM, LEVETIRACETAM IN SODIUM CHLORIDE, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, METHYLPREDNISOLONE, METHYLPREDNISOLONE, METHYLPREDNISOLONE, BISOPROLOL FUMARATE, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, SODIUM BICARBONATE, SODIUM BICARBONATE, INJECTION, SODIUM BICARBONATE INJECTION,,

26842340

EU

Gastrointestinal disorder, Lactic acidosis, Acute kidney injury, Bicytopenia,

DENOSUMAB, ANASTROZOLE, ANASTROZOLE TABLETS, SPIRONOLACTONE, RIBOCICLIB, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, SIMVASTATIN,

26842347

US

Transplant rejection, Acute kidney injury, Pyrexia, Treatment noncompliance,

PEGCETACOPLAN, LISINOPRIL, CLONIDINE, SEVELAMER CARBONATE, PENICILLIN V POTASSIUM, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, MYCOPHENOLIC ACID, MYCOPHENILIC ACID, SALICYLIC ACID, MEDICATED CORN REMOVERS, LIQUID WART REMOVER, ULTRA THIN CORN REMOVERS, EXTRA THICK CALLUS REMOVERS, MEDICATED WART REMOVERS, CORN AND CALLUS REMOVER KIT, WART REMOVERS, WART REMOVER LIQUID, MEDICATED CALLUS REMOVERS, WART REMOVER GEL, MEDICATED PLANTAR WART REMOVER, MEDICATED CALLUS REMOVERS EXTRA THICK, MEDICATED CORN REMOVER, WART REMOVER, CLEAR MEDICATED CORN REMOVERS, CORN REMOVERS, BOSYE BENEFITING HAIR LOTION, LIQUID CORN AND CALLUS REMOVER, WART REMOVER MEDICATED DISCS, WART REMOVER GEL TUBE, SALICYLIC ACID 12%, CALLUS REMOVERS, CORN AND CALLUS REMOVER, GEL CORN REMOVER, ASTRINGENT, SULFAMETHOXAZOLE AND TRIMETHOPRIM, AMLODIPINE,

26842371

US

Primary progressive multiple sclerosis, Condition aggravated, Acute kidney injury,

LOSARTAN, GABAPENTIN,

26842411

US

Hypovolaemic shock, Sprue-like enteropathy, Acute kidney injury,

OLMESARTAN MEDOXOMIL, OLMESARTAN MEDOXOMIL-HYDROCHLOROTHIAZIDE,

26842574

US

Tubulointerstitial nephritis, Acute kidney injury, Metabolic acidosis, Eosinophils urine present,

LEVETIRACETAM, LEVETIRACETAM IN SODIUM CHLORIDE, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION,

26842585

Cardiac failure, Acute kidney injury, Serratia bacteraemia, Gastrointestinal vascular malformation haemorrhagic,

FINERENONE, APIXABAN, FUROSEMIDE, FUROSEMIDE, HYDROCHLOROTHIAZIDE, SULFAMETHOXAZOLE AND TRIMETHOPRIM, SULFAMETHOXAZOLE AND TRIMETHOPRIM, ALLOPURINOL, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, EMPAGLIFLOZIN, MELATONIN, METOPROLOL TARTRATE, METOPROLOL, METOPROLOL TARTRATE INJECTION, PANTOPRAZOLE SODIUM, PANTOPRAZOLE, PANTOPRAZOLE SODIUM IN 0.9% SODIUM CHLORIDE, PANTOPRAZOLE SODIUM INJECTION,

26842642

JP

Acute kidney injury,

DABRAFENIB, TRAMETINIB,

26842648

CN

Rhabdomyolysis, Acute kidney injury,

LEVETIRACETAM, LEVETIRACETAM IN SODIUM CHLORIDE, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, NOREPINEPHRINE (BITARTRATE), NOREPINEPHRINE, NOREPINEPHRINE BITARTRATE, VALPROATE SODIUM, PIPERACILLIN SODIUM,TAZOBACTAM SODIUM, MEROPENEM, TERLIPRESSIN,

26842866

IN

Rhabdomyolysis, Drug interaction, Metabolic acidosis, Hyperkalaemia, Acute kidney injury, Myopathy toxic,

ROSUVASTATIN CALCIUM, DAPAGLIFLOZIN, TICAGRELOR,

26842916

US

Acute kidney injury, Glomerular filtration rate decreased,

BEMPEDOIC ACID,

26842928

AU

Acute kidney injury, Tubulointerstitial nephritis, Blood creatinine increased, Drug eruption,

POSACONAZOLE, POSACONAZOLE DELAYED-RELEASE, PIPERACILLIN SODIUM,TAZOBACTAM SODIUM, VANCOMYCIN HYDROCHLORIDE, VANCOMYCIN,

26843023

KR

Acute kidney injury, Hyperkalaemia, Thrombocytopenia, Renal impairment, Thrombocytopenia, Pericarditis constrictive, Deep vein thrombosis, Pneumonia, Hyperkalaemia, Hyperkalaemia, Gastrooesophageal reflux disease, Dermatitis, Constipation, Anaemia, Hypoalbuminaemia, Decreased appetite, Gastritis, Dysphonia, Vocal cord paralysis, Gait disturbance, Cognitive disorder, Peripheral motor neuropathy, Hypoalbuminaemia, Leukocytosis, Haematuria, Pain in extremity, Oedema peripheral, Abdominal pain, Dyspnoea,

26843672

EU

Hypokalaemia, Pleural effusion, Product use issue, Product use in unapproved indication, Overdose, Febrile neutropenia, Metabolic alkalosis, Toxicity to various agents, Acute kidney injury,

METHOTREXATE SODIUM, LEVETIRACETAM, LEVETIRACETAM IN SODIUM CHLORIDE, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION, RITUXIMAB, METHYLPREDNISOLONE, OMEPRAZOLE, OMEPRAZOLE MAGNESIUM, BISOPROLOL FUMARATE,

26844116

EU

Urinary tract infection, Acute kidney injury,

TIRZEPATIDE, SPIRONOLACTONE, BISOPROLOL FUMARATE, SACUBITRIL AND VALSARTAN, DAPAGLIFLOZIN AND METFORMIN HYDROCHLORIDE,

26844370

SG

Neutropenic sepsis, Multi-organ disorder, Respiratory failure, Haemodynamic instability, Acute kidney injury,

CYTARABINE, IDARUBICIN HYDROCHLORIDE, FLUDARABINE PHOSPHATE,

26844518

US

Rhabdomyolysis, Drug interaction, Acute kidney injury, Hypertransaminasaemia,

RANOLAZINE,

26844595

EU

Hyperkalaemia, Sepsis, Pneumonia pneumococcal, Dyspnoea, Chest pain, Sputum purulent, Septic shock, Peripheral coldness, Livedo reticularis, Respiratory distress, Altered state of consciousness, Acute kidney injury, Cough, Chills, Pyrexia,

VALSARTAN, VALSARTAN ORAL, VALSARTAN, VALSARTAN ORAL, VALSARTAN, VALSARTAN ORAL, VALSARTAN, VALSARTAN ORAL, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, BISOPROLOL FUMARATE, BISOPROLOL FUMARATE, BISOPROLOL FUMARATE, BISOPROLOL FUMARATE, DAPAGLIFLOZIN, DAPAGLIFLOZIN, DAPAGLIFLOZIN, DAPAGLIFLOZIN, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG,

26844680

EU

Acute kidney injury, Thrombocytopenia, Condition aggravated, Anaemia, Renal failure,

RUXOLITINIB, RUXOLITINIB, RUXOLITINIB, EMPAGLIFLOZIN, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, REPAGLINIDE, AMLODIPINE, CANDESARTAN CILEXETIL, SILODOSIN,

26844745

US

Pancreatitis acute, Off label use, Pancreatic pseudocyst, Pancreatitis necrotising, Acute kidney injury, Diabetic ketoacidosis, Hypertriglyceridaemia,

ESTRADIOL,

26834591

EU

Myopathy, Rhabdomyolysis, Acute kidney injury, Hypocalcaemia,

ESCITALOPRAM OXALATE, ESCITALOPRAM, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, PANTOPRAZOLE SODIUM, PANTOPRAZOLE, PANTOPRAZOLE SODIUM IN 0.9% SODIUM CHLORIDE, PANTOPRAZOLE SODIUM INJECTION,

26834652

US

Acute kidney injury, Dehydration, Dysstasia, Muscle spasms,

RISANKIZUMAB-RZAA,

26834810

AU

Neutropenia, Acute kidney injury, Fungal endocarditis, Panophthalmitis, Scedosporium infection,

TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES,

26835112

US

Acute kidney injury, Hypovolaemia, Nausea, Vomiting,

MYCOPHENOLIC ACID, MYCOPHENILIC ACID, PEGLOTICASE, LABETALOL, METHOTREXATE, METHOTREXATE SODIUM, ALLOPURINOL, ESCITALOPRAM, ESCITALOPRAM OXALATE, ESCITSLOPRAM,

26835115

US

Tubulointerstitial nephritis, Acute kidney injury, Angiopathy, Fluid retention, Poor quality sleep,

PRAVASTATIN SODIUM, PREDNISONE, PREDNISONE, PREDNISONE,

26835331

Encephalopathy, Multiple organ dysfunction syndrome, Thyrotoxic crisis, Hyperthyroidism, Cardiac failure, Cardiogenic shock, Hepatotoxicity, Acute kidney injury, Oliguria,

26835617

Distributive shock, Pulmonary oedema, Ventricular fibrillation, Cardiac arrest, Acute kidney injury, Multiple drug therapy,

AMLODIPINE, BUPROPION, LISINOPRIL,

26835702

Acute kidney injury, Metabolic acidosis, Azotaemia, Azotaemia, Pancreatitis acute, Hyponatraemia,

LOSARTAN, LOSARTAN, AMLODIPINE, AMLODIPINE,

26835714

US

Acute kidney injury, Dehydration,

HUMAN IMMUNOGLOBULIN G, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER, DESVENLAFAXINE SUCCINATE, DICYCLOMINE HYDROCHLORIDE, HYDROCORTISONE, MECLIZINE HYDROCHLORIDE, MECLIZINE, MECLIZINE HYDROCLORIDE, VIBEGRON, BACLOFEN, DENOSUMAB, MOMETASONE FUROATE, MOMETASONE, TIZANIDINE HYDROCHLORIDE, RIVAROXABAN, HYDROCORTISONE SODIUM SUCCINATE, LIDOCAINE, LIDOCAINE HYDROCHLORIDE, BURN RELIEF, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE BITARTRATE, LIDICAINE, LIDOCAINE HYDROCHLORIDE AND EPINEPHRINE, LIDOCAINE 4%, LIDOCAINE, MENTHOL, AZELASTINE HYDROCHLORIDE, AZELASTINE, DIAZEPAM, DIAZEPAM ORAL, DIAZEPAM ORAL SOLUTION (CONCENTRATE), RIMEGEPANT SULFATE, SUMATRIPTAN SUCCINATE, TOPIRAMATE, PROMETHAZINE HYDROCHLORIDE, DIPHENHYDRAMINE HYDROCHLORIDE, DIPHENHYDRAMINE HYDROCHLORIDE CAPSULE, LIQUID FILLED, ERGOCALCIFEROL, OXYCODONE AND ACETAMINOPHEN, OXYCODONE HYDROCHLORIDE AND ACETAMINOPHEN, OXYCODONE AND ACETAMINOPHEN TABLETS, QUETIAPINE FUMARATE, QUETIAPINE, LAMOTRIGINE, LAMOTRIGINE EXTENDED-RELEASE, LAMOTRIGINE CHEWABLE DISPERSIBLE, LAMOTIRIGINE,

26835802

EU

Rhabdomyolysis, Acute kidney injury, Drug interaction,

SIMVASTATIN, EZETIMIBE, TORSEMIDE, SPIRONOLACTONE, RAMIPRIL, CARVEDILOL, LACTULOSE, THIAMINE HYDROCHLORIDE, PANTOPRAZOLE SODIUM, PANTOPRAZOLE, PANTOPRAZOLE SODIUM IN 0.9% SODIUM CHLORIDE, PANTOPRAZOLE SODIUM INJECTION, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, SITAGLIPTIN,

26835848

IN

Cardiac failure acute, Lower respiratory tract infection, Acute kidney injury, Electrolyte imbalance, Hypoalbuminaemia, Chest discomfort, Toxicity to various agents, Dyspnoea, Cough, Decreased appetite, Asthenia, Procedural pain, Nasopharyngitis, Left ventricular dysfunction, Off label use,

TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, MYCOPHENOLIC ACID,

26836024

IN

Febrile neutropenia, Acute kidney injury, Hypertension, Venoocclusive disease,

METHOTREXATE, METHOTREXATE SODIUM, CYCLOSPORINE,

26836192

US

Lactic acidosis, Acute kidney injury, Drug level increased, Drug interaction,

METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, LISINOPRIL, LINAGLIPTIN, GLYBURIDE,

26836199

JP

Cytokine release syndrome, Dermatitis exfoliative generalised, Acute kidney injury, Therapy partial responder,

PEMBROLIZUMAB, ENFORTUMAB VEDOTIN,

26836258

US

Acute kidney injury, Shock, Lactic acidosis, Hyperkalaemia,

METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, LINAGLIPTIN,

26836266

Lactic acidosis, Renal tubular necrosis, Metabolic acidosis, Hypoglycaemia, Hyperkalaemia, Toxicity to various agents, Acute kidney injury, Drug interaction,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, LISINOPRIL, ROSUVASTATIN,

26836420

EU

Diabetic ketoacidosis, Lactic acidosis, Acute kidney injury,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, AMLODIPINE BESYLATE AND VALSARTAN, DAPAGLIFLOZIN, INDAPAMIDE, BIMATOPROST, SIMVASTATIN, ALLOPURINOL,

26836543

EU

Hypercalcaemia, Acute kidney injury,

DENOSUMAB,

26836616

Pancreatitis acute, Gastrointestinal necrosis, Intestinal ischaemia, Multiple organ dysfunction syndrome, Septic shock, Respiratory failure, Acute kidney injury, Hypoxia, Pancreatitis necrotising, Pancreatitis acute, Alcoholic pancreatitis, Medical induction of coma, Abdominal pain, Abdominal pain lower, Abdominal pain upper, Dyspnoea exertional, Abdominal distension, Intra-abdominal pressure increased, C-reactive protein increased, Peripancreatic fluid collection, Stoma creation,

ERGOCALCIFEROL,

26836634

EU

Acute kidney injury, Pyuria, Incontinence,

DULOXETINE HYDROCHLORIDE, DULOXETINE, PITOLISANT HYDROCHLORIDE, PITOLISANT HYDROCHLORIDE, PITOLISANT HYDROCHLORIDE, PITOLISANT HYDROCHLORIDE, SILODOSIN, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, SPIRONOLACTONE, SODIUM CHLORIDE, SODIUM CHLORIDE TABLET, SODIUM CHLORIDE TABLETS, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, IRBESARTAN, EMPAGLIFLOZIN, PANTOPRAZOLE, ESCITALOPRAM OXALATE, ESCITALOPRAM,

26836648

Acute kidney injury,

VALACYCLOVIR, VALACYCLOVIR HYDROCHLORIDE, IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN TABLET, FILM COATED, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE,

26836732

EU

Diabetic ketoacidosis, Acute kidney injury, Lactic acidosis,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, AMLODIPINE BESYLATE AND VALSARTAN, INDAPAMIDE, DAPAGLIFLOZIN, SIMVASTATIN, ALLOPURINOL, BIMATOPROST,

26836915

US

Upper gastrointestinal haemorrhage, Acute kidney injury, Metabolic acidosis, Lactic acidosis, Hypotension, Intentional overdose, Drug ineffective,

IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN TABLET, FILM COATED, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE, VASOPRESSIN, NOREPINEPHRINE (BITARTRATE), NOREPINEPHRINE, NOREPINEPHRINE BITARTRATE, EPINEPHRINE, ADRENALINUM,

26836951

US

Dehydration, Acute kidney injury, Lactic acidosis,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, TERAZOSIN, TERAZOSIN HYDROCHLORIDE,

26836956

EU

Thrombotic microangiopathy, Acute kidney injury, Drug ineffective,

EVEROLIMUS, EVEROLIMUS TABLETS, EVEROLIMUS, EVEROLIMUS TABLETS, EVEROLIMUS, EVEROLIMUS TABLETS, EVEROLIMUS, EVEROLIMUS TABLETS, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, BASILIXIMAB, BASILIXIMAB, BASILIXIMAB, BASILIXIMAB,

26837132

US

Acute kidney injury, Renal tubular necrosis, Drug interaction, Fall, Hypotension,

AMLODIPINE, AMLODIPINE, AMLODIPINE, AMLODIPINE, VALSARTAN, VALSARTAN ORAL, VALSARTAN, VALSARTAN ORAL, VALSARTAN, VALSARTAN ORAL, VALSARTAN, VALSARTAN ORAL, EMPAGLIFLOZIN, EMPAGLIFLOZIN, EMPAGLIFLOZIN, EMPAGLIFLOZIN,

26837154

US

Acute kidney injury, Renal ischaemia, Vasoplegia syndrome, Cardiorenal syndrome,

VALSARTAN, VALSARTAN ORAL, SPIRONOLACTONE, FUROSEMIDE,

26837195

Acute kidney injury, Urosepsis, Toxic cardiomyopathy, Toxic epidermal necrolysis, Stevens-Johnson syndrome,

OXCARBAZEPINE,

26837210

EU

Diarrhoea, Duodenal ulcer haemorrhage, Anaemia, Acute kidney injury,

CLOPIDOGREL BISULFATE, IRBESARTAN, FERROUS SULFATE, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, ROSUVASTATIN, TAMSULOSIN HYDROCHLORIDE, ACETAMINOPHEN, ACETAMINOPHEN 500MG, ACETAMINOPHEN TABLET EXTENDED RELEASE, PAIN RELIEVER,

26837338

US

Acute kidney injury, Renal tubular necrosis, Oliguria, Tachycardia, Gait disturbance, Drug interaction,

VALSARTAN, VALSARTAN ORAL, AMLODIPINE, EMPAGLIFLOZIN,

26837882

EU

Hyperkalaemia, Acute kidney injury,

BORTEZOMIB, BORTEZOMIB, DEXAMETHASONE, DEXAMETHASONE 1.5 MG, DEXAMETHASONE, DEXAMETHASONE 1.5 MG, DOXORUBICIN, DOXORUBICIN, VALACYCLOVIR, VALACYCLOVIR HYDROCHLORIDE, FENTANYL, ERYTHROPOIETIN, PANTOPRAZOLE, ALLOPURINOL,

26838119

EU

Acute kidney injury, Cardiotoxicity, Myocarditis, Electrocardiogram QT prolonged, Pneumonitis, Electrocardiogram T wave inversion, Dyspnoea exertional, General physical health deterioration, Hyperglycaemia, Polyuria, Dehydration, Anxiety, Confusional state, Eastern Cooperative Oncology Group performance status worsened, Weight increased, Oedema, Troponin increased, Sinus bradycardia, N-terminal prohormone brain natriuretic peptide increased, Restlessness, Aphasia,

METHYLPREDNISOLONE, DURVALUMAB, CARBOPLATIN, PREDNISONE,

26838289

US

Dehydration, Acute kidney injury, Lactic acidosis,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, TERAZOSIN, TERAZOSIN HYDROCHLORIDE,

26838564

Toxicity to various agents, Confusional state, Candida infection, Mucocutaneous candidiasis, Fungaemia, Infarction, Haematoma, Electrolyte imbalance, Arrhythmia, Supraventricular tachycardia, Loss of consciousness, Drug interaction, Bone marrow failure, Oral pain, Folate deficiency, Acute kidney injury, Encephalopathy, Septic shock, Mucosal inflammation, Fatigue, Pancytopenia,

METHOTREXATE, METHOTREXATE SODIUM, SULFAMETHOXAZOLE AND TRIMETHOPRIM, ABATACEPT,

26838567

Accidental overdose, Toxicity to various agents, Somnolence, Tachycardia, Cachexia, Dehydration, Hypophagia, Blood sodium increased, Inappropriate schedule of product administration, Oral discomfort, Blood creatinine increased, Blood urea increased, White blood cell count decreased, Mean cell volume increased, Platelet count decreased, Aspartate aminotransferase increased, Blood folate decreased, Acute kidney injury, Cytopenia, Hypotension, Diarrhoea, Stomatitis, Encephalopathy,

METHOTREXATE, METHOTREXATE SODIUM, PREDNISONE, SULFAMETHOXAZOLE AND TRIMETHOPRIM,

26838599

Diabetic ketoacidosis, Nephropathy toxic, Pneumonia aspiration, Acute kidney injury,

BUPRENORPHINE HYDROCHLORIDE, NALOXONE HYDROCHLORIDE, PROPYLENE GLYCOL, NICOTINE POLACRILEX, NICOTINE, NICOTINE POLACRILEX MINI, NICOTINE POLARILEX,

26838846

US

Histoplasmosis disseminated, Cholangitis acute, Non-cirrhotic portal hypertension, Ascites, Varices oesophageal, Portal hypertensive gastropathy, Peritonitis bacterial, Immune reconstitution inflammatory syndrome, Acute kidney injury, Suspected off label use,

METHOTREXATE SODIUM,

26839029

US

Metabolic acidosis, Acute kidney injury, Renal tubular necrosis, Encephalopathy, Gastroenteritis cryptosporidial,

BUDESONIDE, SULFASALAZINE, VEDOLIZUMAB, IPILIMUMAB, NIVOLUMAB, PEMBROLIZUMAB,

26839136

US

Lactic acidosis, Acute kidney injury, Dehydration,

METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, LISINOPRIL AND HYDROCHLOROTHIAZIDE, LISINOPRIL AND HYDROCHLOROTHIAZIDE TABLETS, TERAZOSIN, TERAZOSIN HYDROCHLORIDE, AMITRIPTYLINE HYDROCHLORIDE, ATORVASTATIN CALCIUM, ATORVASTATIN CALCIUM, FILM COATED,

26839319

Renal tubular necrosis, Lactic acidosis, Hyperkalaemia, Hypotension, Acute kidney injury, Hypoglycaemia, Product use issue,

TIRZEPATIDE, METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, CLONIDINE, LOSARTAN,

26829776

US

Renal tubular necrosis, Acute kidney injury, Tubulointerstitial nephritis,

IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN TABLET, FILM COATED, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE, ESOMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM, ATENOLOL, AMLODIPINE, VALSARTAN, VALSARTAN ORAL, BACLOFEN, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, ROSUVASTATIN, GABAPENTIN,

26829895

US

Lactic acidosis, Mental status changes, Metabolic acidosis, Intentional overdose, Acute kidney injury, Hypotension, Upper gastrointestinal haemorrhage,

IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN TABLET, FILM COATED, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE,

26829903

IN

Idiopathic pneumonia syndrome, Rheumatoid arthritis, Acute kidney injury, Urosepsis, Heart failure with reduced ejection fraction, Lower respiratory tract infection, Cardiac failure acute, Pneumonia klebsiella, Toxicity to various agents, Hypoalbuminaemia, Electrolyte imbalance, Gastroenteritis, Infection, Blood test abnormal, Dehydration, Urinary tract infection, Abdominal pain, Asthenia, Nausea, Diarrhoea, Vomiting, Off label use,

TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, MYCOPHENOLIC ACID, MYCOPHENOLIC ACID,

26830021

US

Acute kidney injury, Tubulointerstitial nephritis, Renal tubular necrosis,

ESOMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM, ESOMEPRAZOLE MAGNESIUM CAPSULE, DELAYED RELEASE, ESOMEPRAZOLE MAGNESIUM DIHYDRATE, ESOMEPRAZOLE MAGNESIUM DELAYED RELEASE CAPSULES, IBUPROFEN, IBUPROFEN CAPSULES 200 MG, IBUPROFEN TABLETS USP, 200MG, IBUPROFEN TABLET, FILM COATED, IBUPROFEN ORAL, IBUPROFEN 200MG, IBUPFROFEN, IBUPROFEN TABLET, FILM-COATED, IBUPROFEN 200 MG, IBUPROFEN CAPSULE, ATENOLOL, AMLODIPINE, VALSARTAN, VALSARTAN ORAL, BACLOFEN, ASPIRIN, ASPIRIN 81 MG, ASPIRIN 325 MG, ROSUVASTATIN, GABAPENTIN,

26830023

US

Pancreatitis acute, Acute kidney injury,

LOSARTAN POTASSIUM, LOSARTAN, AMLODIPINE,

26830056

Acute kidney injury, Metabolic acidosis, Azotaemia, Azotaemia, Pancreatitis acute, Hyponatraemia,

LOSARTAN, LOSARTAN, AMLODIPINE, AMLODIPINE,

26830271

Acute kidney injury, Drug interaction,

CYCLOSPORINE, ACYCLOVIR, ACYCLOVIR, MYCOPHENOLIC ACID, MYCOPHENILIC ACID,

26830329

US

Tubulointerstitial nephritis, Acute kidney injury,

LEVETIRACETAM, LEVETIRACETAM IN SODIUM CHLORIDE, LEVETIRACETAM ORAL, LEVETIRACETAM INJECTION,

26830336

EU

Acute kidney injury, Vomiting, Nausea, Diarrhoea,

OXALIPLATIN, FLUOROURACIL CREAM, 0.5%, FLUOROURACIL, LEUCOVORIN CALCIUM,

26830343

EU

Thrombotic microangiopathy, Acute kidney injury, Haemoglobin decreased, Platelet count decreased, Blood lactate dehydrogenase increased, Blood pressure systolic increased, Off label use,

BASILIXIMAB, EVEROLIMUS, EVEROLIMUS TABLETS, EVEROLIMUS, EVEROLIMUS TABLETS, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES,

26830367

US

Acute kidney injury, Nephropathy toxic, Treatment noncompliance, Multiple sclerosis relapse, Neurological decompensation,

SULFAMETHOXAZOLE AND TRIMETHOPRIM, GABAPENTIN, LOSARTAN,

26830524

Pancreatitis, Azotaemia, End stage renal disease, Acute kidney injury,

LOSARTAN, LOSARTAN, AMLODIPINE, AMLODIPINE,

26830815

US

Haematoma, Arrhythmia, Electrolyte imbalance, Drug interaction, Toxicity to various agents, Pancytopenia, Encephalopathy, Mucosal inflammation, Septic shock, Candida infection, Mucocutaneous candidiasis, Immunosuppression, Acute kidney injury,

METHOTREXATE, METHOTREXATE SODIUM, SULFAMETHOXAZOLE AND TRIMETHOPRIM, ABATACEPT,

26830816

EU

Thrombotic microangiopathy, Acute kidney injury,

BASILIXIMAB, EVEROLIMUS, EVEROLIMUS TABLETS, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES,

26830857

US

Acute kidney injury, Drug-disease interaction, Lactic acidosis,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, GLIMEPIRIDE, INSULIN GLARGINE-YFGN, INSULIN GLARGINE, TERAZOSIN, TERAZOSIN HYDROCHLORIDE,

26830933

US

Septic shock, Colitis, Pancytopenia, Hypotension, Acute kidney injury, Cholecystitis, Agonal respiration, Hypophagia, Asthenia, Diarrhoea, Tachycardia, Product use in unapproved indication,

DEXAMETHASONE, DEXAMETHASONE 1.5 MG, DEXAMETHASONE, DEXAMETHASONE 1.5 MG, LENALIDOMIDE, DENOSUMAB,

26831130

EU

Thrombotic microangiopathy, Acute kidney injury, Off label use,

BASILIXIMAB, EVEROLIMUS, EVEROLIMUS TABLETS, EVEROLIMUS, EVEROLIMUS TABLETS, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, BASILIXIMAB, BASILIXIMAB,

26831174

US

Lactic acidosis, Acute kidney injury, Shock,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, LINAGLIPTIN,

26831184

Lactic acidosis, Dehydration, Acute kidney injury,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, INSULIN GLARGINE-YFGN, INSULIN GLARGINE, TERAZOSIN, TERAZOSIN HYDROCHLORIDE,

26831296

EU

Lactic acidosis, Acute kidney injury, Gastrointestinal disorder, Bicytopenia,

ANASTROZOLE, ANASTROZOLE TABLETS, SPIRONOLACTONE, DENOSUMAB, RIBOCICLIB, METFORMIN HYDROCHLORIDE, METFORMIN, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE TABLETS, METFORMIN HYDROCHLORIDE TABLET, METFORMIN HYDROCHLORIDE TABLETS, SIMVASTATIN,

26831401

US

Acute kidney injury, Unevaluable event,

PEGLOTICASE,

26831427

CA

Acute kidney injury, Adverse reaction, Gait inability, Aphasia,

UPADACITINIB, UPADACITINIB,

26831436

IN

Cardiac failure acute, Lower respiratory tract infection, Acute kidney injury, Electrolyte imbalance, Hypoalbuminaemia, Toxicity to various agents, Dyspnoea, Chest discomfort, Cough, Nasopharyngitis, Procedural pain, Asthenia, Decreased appetite, Left ventricular dysfunction, Off label use,

MYCOPHENOLIC ACID, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES,

26831497

Euglycaemic diabetic ketoacidosis, Lactic acidosis, Acute kidney injury,

METFORMIN, METFORMIN ER 500 MG, METFORMIN ER 750 MG, LINAGLIPTIN,

26831613

US

Acute kidney injury, Hepatic fibrosis, Hepatic steatosis, Hypoalbuminaemia, Transaminases increased, Drug level fluctuating, Clostridium difficile infection, Cytomegalovirus viraemia,

TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, PREDNISONE, MYCOPHENOLIC ACID, MYCOPHENILIC ACID,

26831671

EU

Acute kidney injury, Intracranial pressure increased, Intracranial pressure increased,

26831693

CN

Acute kidney injury, Gastrointestinal erosion, Gastric ulcer, Ileal ulcer, Haemophagocytic lymphohistiocytosis, Hypoalbuminaemia, Large intestine polyp, Gastrointestinal haemorrhage, Myelosuppression, Dengue fever, Anaemia, Product use in unapproved indication,

OXALIPLATIN, FLUOROURACIL CREAM, 0.5%, FLUOROURACIL, LEUCOVORIN CALCIUM, METHYLPREDNISOLONE, BASILIXIMAB, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, TACROLIMUS, TACROLIMUS OINTMENT 0.1%, TACROLIMUS EXTENDED-RELEASE CAPSULES, PREDNISONE,

26831750

EU

Drug reaction with eosinophilia and systemic symptoms, Acute kidney injury, Eosinophilia,

ALTEPLASE, HEPARIN SODIUM,