There are long-standing reports of sexual dysfunction linked to the use of isotretinoin, a retinoid drug used in the treatment of acne. FDA and MHRA received the first reports of sexual dysfunction involving isotretinoin in 1983 and 1985 respectively, and according to a publication in The Lancet, Roche had received 150 reports of problems affecting the male reproductive system … [Read more...] about Post-Retinoid Sexual Dysfunction (PRSD) Petition
Sex
Skin and Drugs and Sex
Editorial Note: This post returns to PSSD - post SSRI sexual dysfunction - PRSD - post retinoid sexual dysfunction - PFS - post finasteride sexual dysfunction and PGAD - persistent genital arousal disorder. See our RxISK PSSD page for the many prior posts on these conditions There is also post on davidhealy.org - Khashoggi and Pandemrix - which might not sound like it is … [Read more...] about Skin and Drugs and Sex
Can Antidepressants Make You Less Attractive?
In recent years, there has been increasing concern about the problem of antidepressants finding their way into the environment. These drugs aren't fully absorbed by the body and are present in human waste. Small concentrations are then flowing into rivers via wastewater treatment facilities where wildlife can be affected. In August 2018, several media outlets reported that … [Read more...] about Can Antidepressants Make You Less Attractive?
Post-Finasteride Syndrome & Amino Acids
Editorial Note: This post has just arrived. We need to know if the treatment outlined makes any difference to others with PFS, PSSD and PRSD. It looks safe to test. You can help us by testing it if you have one of these conditions. We'd also like to know if you are aware of any reasons why it might not be helpful - others have tried it - or if you think it could be helpful … [Read more...] about Post-Finasteride Syndrome & Amino Acids
PSSD In The Guardian, U.S. News & Lyon Capitale
The Guardian The Guardian, a British newspaper, runs a weekly feature called “My life in sex”, in which readers can write in and talk about their sex life. On June 8, 2018, they ran a piece called “After taking antidepressants, my genitals felt numb”. A 30 year old women described how she had been left with post-SSRI sexual dysfunction (PSSD) since stopping an SSRI eight … [Read more...] about PSSD In The Guardian, U.S. News & Lyon Capitale
What to do about Sex
The recent RxISK post on PSSD and Thermal Thresholds led to a lot of comments about what should "we" - those with PSSD or related conditions - do. There was a looking out to FDA or other regulators, doctors or politicians to do something. Coincidentally on davidhealy at the same time a pair of posts on antidepressant induced suicide in children, The Greatest Failure and … [Read more...] about What to do about Sex
Antidepressants, Sex and Thermal Thresholds
Last month, we announced details of two new publications about enduring sexual dysfunction after the use of medications. We hope you found them interesting. In both articles, we discussed a couple of studies from 1991 and 1999, in which neurophysiological testing showed that taking a serotonin reuptake inhibitor reduces genital sensation. We have previously mentioned these … [Read more...] about Antidepressants, Sex and Thermal Thresholds
My PGAD Nightmare
Editorial Point: This post is both an extraordinary account of PGAD (Persistent Genital Arousal Disorder) but also an extraordinary account of what many people have to put up with from psychiatry. For some of the history of PGAD see our Citizen's Petition to FDA. See also the video clip on PGAD. At the beginning of 2017, I started a kafkaian journey that gave me a mental … [Read more...] about My PGAD Nightmare
Enduring Sexual Dysfunction: 300 Cases
New publications After a great deal of work, we are pleased to announce details of two new publications in the International Journal of Risk & Safety in Medicine. The pre-print versions are currently available. [Now updated with printed versions - June 11, 2018.] The first is our new paper – Enduring sexual dysfunction after treatment with antidepressants, 5α-reductase … [Read more...] about Enduring Sexual Dysfunction: 300 Cases
PSSD, Withdrawal & Small Fiber Neuropathy?
The picture here shows the before and after feet of a person who has erythromelalgia. After exercise or in response to other triggers, sometimes just lying in bed, the feet or other body parts can become hot and burning, possibly painfully so. The condition is linked to sodium channels. Those who get it may have a genetic variation predisposing them to it. Those who get it have … [Read more...] about PSSD, Withdrawal & Small Fiber Neuropathy?