The Serotonin Reuptake Inhibitor (SRI) story starts in 1969 with Arvid Carlsson (above) who created Zelmid, the first SRI, after listening to people on antidepressants. He linked an anxiolytic effect some older drugs have to the serotonin system. The SRIs aimed at exploring that effect - Normality and Antidepressant Dysregulation. Fluoxetine (Prozac). sertraline (Zoloft). … [Read more...] about Restoring the Magic to Healthcare
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Antidepressants: Education and Disability Certificates
This post covers difficulties primarily on antidepressants that medicines can cause to people in schools or universities who end up unable to study or do course-work, as well as the difficulties people can have trying to get off medicines, a process that can be pretty disabling. The materials linked to this post are being put in your hands to run an experiment and hopefully … [Read more...] about Antidepressants: Education and Disability Certificates
Encountering Doctors
Editorial Note: The image goes with a study headlined Doctors stop listening to patients several seconds into a conversation. This post is from one of the many PSSD sufferers who behind the scenes has been helping push research on this awful condition forward. It would be a lot easier if doctors did listen. Just as the brain and the human nervous system are largely … [Read more...] about Encountering Doctors
Can Antidepressants Make You Less Attractive?
In recent years, there has been increasing concern about the problem of antidepressants finding their way into the environment. These drugs aren't fully absorbed by the body and are present in human waste. Small concentrations are then flowing into rivers via wastewater treatment facilities where wildlife can be affected. In August 2018, several media outlets reported that … [Read more...] about Can Antidepressants Make You Less Attractive?
My Trip Through the Polypharmacy Blender
By Rory Tennes I was asked by David Healy to write my own story after he read my comment on another RxISK story. I agreed but have been surprised how hard it was to sit down and do it. I knew the story, the words were in my head. Yet I avoided getting started. Perhaps it was because of the painful emotions I knew it would bring to the surface. Or maybe because it reminds me … [Read more...] about My Trip Through the Polypharmacy Blender
The Year of My Life that was Stolen
This post is by Katinka Blackford-Newman, who can be seen here running a half-marathon to raise money for RxISK but who also since the events described here has been involved in several criminal trials, believing that it is important that juries get to hear stories like hers when faced with the challenge of assessing what contribution a drug might have made to a crime. There … [Read more...] about The Year of My Life that was Stolen
Abilify from the Inside Out
Editorial Note: This is part 2 of Johanna Ryan's series that started with Dodging Abilify. Abilify is at present the best-selling drug in North America - how come? In last week’s column, Dodging Abilify, I described the fan-club enthusiasm for this drug among doctors I’ve met, my own reluctance to try it, and what I’d learned about Abilify from casual research. This week … [Read more...] about Abilify from the Inside Out
Dodging Abilify
Editorial Note: This post is by Johanna Ryan, who has a unique ability to capture the American Nightmare. The best-selling drug in the United States isn’t a blood pressure pill, a painkiller or even an antidepressant. It’s Abilify, an antipsychotic agent with $6.3 billion in 2013 sales. Granted, Abilify isn’t the most prescribed pill, but its #1 status is sealed by popularity … [Read more...] about Dodging Abilify
A Blast from the Past: Amphetamines for Weight Loss
Author: Johanna Ryan The story below, a first-person account of life on (and off) amphetamine “diet pills,” was written over forty years ago. It couldn’t be more relevant. Under the cover of a public-health crusade against obesity, drug companies are bringing back old-fashioned “speed” in brand-new packages. Last week’s post described the newly-approved weight loss pill … [Read more...] about A Blast from the Past: Amphetamines for Weight Loss
The Show Ain’t Over Till the Fat Lady Sings
By Johanna Ryan As 2015 dawns, the specter of Corporate Personhood, sanctified by trade treaties which put patents and profits above the needs of us humans, seems to be drawing ever closer. Our latest wake-up call came from the respected French drug safety journal Prescrire. They’re sounding the alarm about a December 19 vote by the EU’s Committee on Medicinal Products for … [Read more...] about The Show Ain’t Over Till the Fat Lady Sings