Sexual Dysfunction Enduring After Treatment Halts: Sexual-DEATH

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February 10, 2014 | 11 Comments


  1. Being struck-down in your youth by one of these medications is dually insulting.

    Not only are you doomed to carry-on with your life dealing with embarrassing sexual, debilitating mental, and sometimes even physical side effects, but doctors will often refuse to report or acknowledge your symptoms as a drug side effect because it is supposedly “unheard of”.

  2. Well written article.

    I enjoy accutane induced sexual dysfunction 15 months after taking one 20mg pill every day for a grand total of 10 days. Thankfully the other side effects I got have greatly subsided i.e the severe gastric issues, the fatigue and the emotional blunting.

  3. The Medicines and Healthcare Products Regulatory Agency Are Ignoring Their Data On PSSD.

    I have had PSSD in the form of Impotence for the last 18 years following a brief period of Prozac just after my 18th birthday, becoming impotent after beginning Prozac and having since never had a proper erection to this day. Following numerous medical tests Doctors have attributed my impotence to the Prozac I took in 1996. I reported the persistence of my Prozac induced impotence to the MHRA using the Yellow Card Scheme but my report was not acknowledged.

    Years later, in 2008 when PSSD had become more widely known about and studies into the persistence of PSSD had begun to be published I began writing to the MHRA. Initially they informed me of a mere 83 Adverse Drug Reaction reports of SSRI-induced sexual dysfunction with 8 of the reports being of sexual dysfunction persistent after discontinuation. After I pressed them further, and they changed their database search criteria they came back with a figure of over 1000 reports of anti depressant induced sexual dysfunction with over 200 being persistent, and over 100 persisting at the time that they were reported to the MHRA.

    Through persistent Freedom Of Information Act requests I`ve got Sarah Cumber, Pharmacovigilance Information Co-ordinator to make the very damning admission that the MHRA have no record of following up the 940 reports of Adverse Drug Reactions of SSRI-related sexual dysfunction they received prior to June 2006 when they claim a change to their database resulted in this information being lost.

    Leaving aside how pathetic and unbelievable an excuse this was, surely it should be expected that the MHRA would have done whatever it could to retrieve the follow up information on these reports of adverse drug reactions? Once the change to the database had occurred shouldn’t they have been doing all possible to contact the patients who made their reports to record the outcome of their adverse drug reactions?

    Well the MHRA didn`t. It took them over 4 years following the alleged loss of follow up information, to by August 2010, follow up any of the reports and it was only in response to my ongoing Freedom Of Information Act Requests probing into their follow up on reports of PSSD that the MHRA made any attempt to retrieve this information.

    The MHRA stated that in August 2010 they chased up only 32 of the 940 Adverse Drug Reactions received prior to their database change of whom none responded. I do not find it plausible that 32 patients who went to the effort to report their sexual dysfunction via the Yellow Card Scheme would ignore correspondence from the MHRA enquiring into the outcome of the adverse effects that they reported.

    Despite that the MHRA had to admit that they retain contact information for 892 of the 940 patients who made their reports prior to the alleged loss of follow up information, the MHRA has refused to contact any more of them.

    In summary the MHRA`s performance in relation to PSSD is as follows, and I will be happy to send the documented evidence of this to anyone who requests the information;

    The MHRA have no record of following up any of the 940 reports relating to SSRI induced adverse sexual effects received prior to June 2006

    In August 2008 they initially informed me that they had received only 83 reports of Adverse Drug Reactions relating to SSRI induced adverse sexual effects and assured me that the matter was under “close review”.

    Only by August 2010 did they follow up any of the adverse drug reaction reports which they now admit were 940 in number, and they followed up only 32 of them claiming none responded.

    In their most recent response to my Freedom Of Information Act request dated 8th November 2013 the MHRA admitted that out of 1220 reports of SSRI Induced sexual dysfunction received, 266 of the reports were of adverse sexual effects that persisted after the patient stopped taking the drug.

    Despite that 1087 reports contained the Patient`s contact information, to date only 117 have been followed up and this number of follow ups has been achieved only through persistent information requests and efforts to keep account of their responses to adverse drug reaction reports.

    The MHRA remain unprepared to provide even a precautionary warning regarding the persistence of SSRI-induced sexual dysfunction and in spite of all the overwhelming evidence, have never been prepared to refer to the persistence of SSRI induced sexual dysfunction as anything more than a “potential signal” as to a symptom of the medication.

    • Kevin – I’d also be interested in seeing your papers if you are able to share easily – Good wishes, Jeremy

    • Please send me all your records. My state raped me with a Jarvis law that forced the drug abilify on me and killed my sexuality. I’m a 32 year old female. Also since trying the drug I have new long lasting episodes of disphoria and emotional imbalance. I have affected for ten months and off all ssri drugs for 30 days.

  4. I have PSSD since December 2013, after 3 days or more i felt numb down there, this doesn’t changed until this day, it´s very frustrating for anyone live with this condition, and the worse thing is to live with something you that do not know if someday will be reversed and cured.

  5. After 6 weeks of Zoloft (Sertraline) I have been left dealing with PGAD or RGS. This symptom commenced approx 4 weeks after cessation of Sertraline 6 months ago, no improvement as yet.

    I am for the first time in my life suicidal.

  6. i also affected with Paxera which is Turkish made SSRI replacement of Paxil. No one believed, my doctor didn’t want to agree it. i don’t know what to do. i was completely ok and there was nothing about my sexual functions.after drug even my penis soft size also reduced. its unbelievable but true unfortunately

    • I was interested to read your post. I have suffered moderate SSRI sexual dysfunction for a couple of years. Recently this has go a lot worse and like you the size of my soft penis has decreased significantly. It is no. “super soft” and much smaller than it was. I hope there is help somewhere…..
      My libido has almost vanished and I have no interest in masturbating anymore.

      Good luck to you

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