Some weeks ago, in Antidepressants and Premature Death RxISK featured an article by Narinder Balsal and colleagues from Bristol in the British Journal of Psychiatry, which caused quite a fuss. See below. Today we are posting about another article by her in PLoS Medicine. This comes with an Animated Trailer - the first RxISK post to feature one. The article - … [Read more...] about Harry and Meghan and Narinder
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Charles Dickens and Red Tape, Alive and Well in 2023
This post is a follow up to Great Treatment, Patient Dead and to last weeks 'Twas the Nice before Christmas. This image is almost unreadable but worth presenting as it's the first mention of Red Tape - short for Red Tapeworm. The full, readable text can be found here The Circumlocution Office. Red Tape is a highly topical way to start the New Year. Dickens was … [Read more...] about Charles Dickens and Red Tape, Alive and Well in 2023
Twas the NICE before Christmas.
To the Sounds of a Drum © Nina Otulakowski November 2022 This letter, which has had no response, needs to be read in conjunction with Can you Hear the Suzerain Call? Letter to Dr S Roberts, CEO, Ms Nebhrajani, Chair, NICE November 30 2022 Dear Drs Roberts and Ms. Nebhrajani I wrote to your predecessors Dr Haslam and Mr. Dillon just under 3 years ago about the issues of … [Read more...] about Twas the NICE before Christmas.
Getting Off Proton Pump Inhibitors
I would like to describe my experiences with Omeprazole / Esomeprazole to warn others of the ease with which it is possible to become hooked on this medicine, or other so called Proton Pump Inhibitors PPIs. To start with here is an explanation of these drugs that could have saved me about 9 months of trouble plus considerable worry. I just wish I had discovered … [Read more...] about Getting Off Proton Pump Inhibitors
A Cure for PSSD, PFS and Post-Isotretinoin Syndrome
The Holy Grail © Nina Otulakowski June 2022 You need to click on the image to get the full effects. In recent months, RxISK has been working closely with Luisa Guerrini in Milan, whose background is in research on regulatory proteins like p 63 and p 53, on which Thalidomide works. This discovery led to excitement a few years ago when it was thought the mechanism through which … [Read more...] about A Cure for PSSD, PFS and Post-Isotretinoin Syndrome
Our Unequal Struggle with Health Systems
This is Lacoon, a Trojan priest, and his sons being engulfed and killed by snakes from the deep as he tried to warn the Trojans about the Horse they were planning to pull inside their walls. Gordon Hughes case, outlined last week in Treatment Great, Patient Died, shares a lot in common with Evelyn, Kafka, Jack and Luise in the same post. Unfortunately, most readers … [Read more...] about Our Unequal Struggle with Health Systems
The Treatment was Great, The Patient Died
This post contains a letter sent on October 31, 2022 to the Minister for Mental Health in Scotland about Gordon Hughes pictured here with his mother a few weeks before the events outlined below. Pictures and headings have been added. Kevin Stewart MSP, Minister for Mental Wellbeing and Social Care, MinisterMWSC@gov.scot Dear Mr. Stewart, I was recently approached by … [Read more...] about The Treatment was Great, The Patient Died
Science, Kansas and the Wizard of Washington
This post follows on from Science, Kansas and Pancakes. Peter is doing a good job spreading word of this article on the Prozac studies in children and featuring other aspects of this extraordinary story. This post focusses in on one revelatory feature. Reviewer #3: A window with the view on the details of how drug approval proceeds. Very informative and helpful for … [Read more...] about Science, Kansas and the Wizard of Washington
Science, Kansas and Pancakes
A long time ago, following work on the Restoration of Study 329, I was approached by Peter Goetzsche, featured above, to work on restoring the two trials that had got Prozac (fluoxetine) approved for children for depression. I may have suggested this idea to Peter in that from 2004 or so I was aware that reviewers in the US FDA had concluded that although they were going to … [Read more...] about Science, Kansas and Pancakes
PSSD Patients Needed for Small Fibre Neuropathy Investigation
We recently ran a couple of blog posts about the possibility of a link between post-SSRI sexual dysfunction (PSSD) and small fibre neuropathy: Sensory Receptors, Small Fibres and Neuropathy Antidepressant Neuropathy and the Color of Life The posts recapped some of the things we had previously discussed on the blog and also included new information about a Finnish … [Read more...] about PSSD Patients Needed for Small Fibre Neuropathy Investigation