I recently had a request for input on akathisia and withdrawal related issues that for some reason charmed me into responding. The back and forth however began to sink into a quicksand that can put me off responding. There is an old aphorism about experts – a true expert is s/he who knows how little s/he knows. Sounds cute but it’s not what anyone who consults someone they … [Read more...] about Treatment Complications: Good Expert Needed
Withdrawal
Withdrawal, PSSD and Cholinergic Drugs
Health Warning I don’t know a great deal about the issues in this post. Experts by Experience and The Marketing of Anticholinergic Maleficence along with Psychotropic Drug Follies will give some feel for the background that makes it difficult to be certain about anything linked to the cholinergic drugs. The Past Present and Future article will need to be downloaded to take to … [Read more...] about Withdrawal, PSSD and Cholinergic Drugs
How the Safety of Drugs was Destroyed
Emer Cooke, the CEO of the European Medicines Agency (EMA) is Irish. This is Dublin's famous Halfpenny Bridge which for some reason features in an article outlining the history of the phrase Tail wags Dog which seems appropriate for what followed. I wrote to Emer recently about a bizarre letter I received from Kinapse - A Brush with EMA - who run EMA's medical literature … [Read more...] about How the Safety of Drugs was Destroyed
PPPD – Persistent Postural Perceptual Dizziness
This post is from R, whom I came into contact with at least a decade ago. She had significant SSRI dependence and withdrawal issues. And was very discombobulated by the difficulties she was having. Back in 1997 after a difficult and stressful house move I went to see my Family Doctor because I was getting a lot of headaches and panic attacks in crowded places. She said I was … [Read more...] about PPPD – Persistent Postural Perceptual Dizziness
The Long Awaited PSSD Research Breakthrough?
This image is from an extraordinary blog which tells you how to sex your mouse Breakthrough? Most of the good ideas that RxISK has featured linked to the enduring sexual dysfunctions, whether PSSD, PRSD, PFS and PGAD, and in terms of other problems, have come from readers of these posts. Several readers have stood out in terms of contributions and this post comes from one of … [Read more...] about The Long Awaited PSSD Research Breakthrough?
Pyridoxal-5-Phosphate and Akathisia
This post came from a regular contributor to RxISK and DH posts. An earlier comment pointed to something interesting and has developed into this post which should be of interest to anyone who has a withdrawal problem that entails some kind of akathisia. When I came out of a psychiatric hospital in Summer 2019, I had been on zopiclone for a good 6 months. For most of that … [Read more...] about Pyridoxal-5-Phosphate and Akathisia
Withdrawal Mysteries. Jon and Justin’s Journeys
Being Hooked to and having to Withdraw from Antidepressants, especially any that act on the serotonin system, is one of the greatest public health issues of our day. Close to 15 per cent of the population of most Western countries are affected. Peter Groot and colleagues in the Netherlands have done more than anyone to raise the profile of these issues by providing a method … [Read more...] about Withdrawal Mysteries. Jon and Justin’s Journeys
Sexual Mysteries. What is in a Touch?
This is an important post for anyone hunting for a test for PSSD. If the CT fibres mentioned here are not fibres that show up distinctly on either skin biopsy or CCM, then these tests may not pick up a very real problem. We need some research on whether CT fibres show around the ankle or in the cornea. The slide above is from a fascinating lecture on Affective Touch by Francis … [Read more...] about Sexual Mysteries. What is in a Touch?
The Window to the Body and perhaps the Soul
It might sound corny but it has long been said that our Eyes are the Window to our Soul. Whatever about the soul, every medical student gets told by ophthalmologists that the Eyes are the Window to the Body. They claim to be able to detect almost every possible disease by looking at our eyes. Just over a decade ago, Corneal Confocal Microscopy (CCM) came into view. See CCM - … [Read more...] about The Window to the Body and perhaps the Soul
Touch Fibres, Autonomic Fibres and Kissing
Someone, who regularly emails breaking research that I haven't spotted or don't have time to spot, got in touch recently with great insights on an article about Kisspeptin that I had seen. But I had managed to miss several things he spotted that may be important to anyone thinking about PSSD. A Kiss Before Sex The article reported a clinical trial on the Effects of Kisspeptin … [Read more...] about Touch Fibres, Autonomic Fibres and Kissing