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Embracing Healthcare’s Opportunities

October 28, 2024 8 Comments

Up to 1980, the pharmaceutical industry was small beer.  Most of the companies had recently demerged from chemical companies, and were hiring management consultants to help them work out how to do the job. A steady stream of life-saving drugs from the 1940s to 1960s that people and health services were willing to buy at prices greatly in excess of their costs of production … [Read more...] about Embracing Healthcare’s Opportunities

How the Safety of Drugs was Destroyed

August 22, 2023 14 Comments

Emer Cooke, the CEO of the European Medicines Agency (EMA) is Irish. This is Dublin's famous Halfpenny Bridge which for some reason features in an article outlining the history of the phrase Tail wags Dog which seems appropriate for what followed. I wrote to Emer recently about a bizarre letter I received from Kinapse - A Brush with EMA - who run EMA's medical literature … [Read more...] about How the Safety of Drugs was Destroyed

Podcasts, YouTube Channels, Blogs and Related

January 23, 2023 3 Comments

In some of the comments after the last post, POGO mentioned that Josef Witt-Doerring has done two interviews with me so far and posted them on his site. The Risks of Antidepressants  and Antidepressants and Mass Shootings/Murder Suicide: An interview has also appeared on Demystifying Science podcast with  Anastasia & Michael Shilo The Podcast called … [Read more...] about Podcasts, YouTube Channels, Blogs and Related

Antidepressant Neuropathy and the Color of Life

October 10, 2022 16 Comments

Is there life after meds?

Illustration: Is There Life After Meds?, © 2014 created by Billiam James Here is a Question put to the recent RxISK post on Sensory Neuropathy. I’m a psychologist and I have made numerous attempts to discontinue antidepressants only to experience significant withdrawal symptoms. I’ve been on antidepressants for 25 years at this point and have made four unsuccessful attempts … [Read more...] about Antidepressant Neuropathy and the Color of Life

Antidepressants and Premature Death

October 5, 2022 25 Comments

An article appeared in the British Journal of Psychiatry some weeks ago, by Narinder Bansal and colleagues from Bristol University. Having met Narinder I can tell readers she is a very impressive woman, with an impressive husband, Petros, who are both in one way or another working on population health.  She had been working in cardiovascular medicine but switched to … [Read more...] about Antidepressants and Premature Death

Sensory Receptors, Small Fibres and Neuropathy

September 21, 2022 35 Comments

RxISK began in 2012. One of its main goals was to offer people an opportunity to report problems they had on treatments – any treatment – and generate a report they could take to a doctor in the hope this might get the doctor to take their problem seriously. I had seen my first cases of Post-SSRI Sexual Dysfunction (PSSD) in 2000, had been writing about withdrawal since the … [Read more...] about Sensory Receptors, Small Fibres and Neuropathy

All DRESSed Up With Nowhere To Go

August 9, 2022 5 Comments

This post was written by several members of the RxISK Team drawing on the work of Jorge Carrasco - see below.  There is a prior RxISK post on DRESS Syndrome - No Way to Treat a Lady. María Elisa Rangel was 38 and a mother of four children when she signed up for a phase 1 clinical trial in April 2015. They needed the money. The drug was cenobamate, marketed by SK Life … [Read more...] about All DRESSed Up With Nowhere To Go

Clinical Trial Fraud

June 28, 2021 13 Comments

This is part two of Johanna Ryan's posts on Ghosts in the Clinical Trial Machine or Clinical Trial Fraud. Last weeks post reported on how doctors in three states have been convicted of handing in fake clinical-trial results from fake patients. This week we’ll examine how small-time crooks like these ended up doing world-class medical research for companies like GSK. Medical … [Read more...] about Clinical Trial Fraud

Ghosts in the Clinical Trial Machine

June 21, 2021 18 Comments

This is the first part of a two part series on clinical trial fraud from Johanna Ryan, with part 2 next week. Jo is RxISK's clinical trial and shoddy clinical practice sleuth - see The Maintenance Man.   Recently the U.S. Department of Justice called attention to a small but worrisome crime wave. Health care fraud is a familiar feature of American life that may account for … [Read more...] about Ghosts in the Clinical Trial Machine

Antidepressants: Education and Disability Certificates

March 22, 2021 38 Comments

This post covers difficulties primarily on antidepressants that medicines can cause to people in schools or universities who end up unable to study or do course-work, as well as the difficulties people can have trying to get off medicines, a process that can be pretty disabling. The materials linked to this post are being put in your hands to run an experiment and hopefully … [Read more...] about Antidepressants: Education and Disability Certificates

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