To the Sounds of a Drum © Nina Otulakowski November 2022 This letter, which has had no response, needs to be read in conjunction with Can you Hear the Suzerain Call? Letter to Dr S Roberts, CEO, Ms Nebhrajani, Chair, NICE November 30 2022 Dear Drs Roberts and Ms. Nebhrajani I wrote to your predecessors Dr Haslam and Mr. Dillon just under 3 years ago about the issues of … [Read more...] about Twas the NICE before Christmas.
Antidepressants
A Cure for PSSD, PFS and Post-Isotretinoin Syndrome
The Holy Grail © Nina Otulakowski June 2022 You need to click on the image to get the full effects. In recent months, RxISK has been working closely with Luisa Guerrini in Milan, whose background is in research on regulatory proteins like p 63 and p 53, on which Thalidomide works. This discovery led to excitement a few years ago when it was thought the mechanism through which … [Read more...] about A Cure for PSSD, PFS and Post-Isotretinoin Syndrome
Our Unequal Struggle with Health Systems
This is Lacoon, a Trojan priest, and his sons being engulfed and killed by snakes from the deep as he tried to warn the Trojans about the Horse they were planning to pull inside their walls. Gordon Hughes case, outlined last week in Treatment Great, Patient Died, shares a lot in common with Evelyn, Kafka, Jack and Luise in the same post. Unfortunately, most readers … [Read more...] about Our Unequal Struggle with Health Systems
Science, Kansas and the Wizard of Washington
This post follows on from Science, Kansas and Pancakes. Peter is doing a good job spreading word of this article on the Prozac studies in children and featuring other aspects of this extraordinary story. This post focusses in on one revelatory feature. Reviewer #3: A window with the view on the details of how drug approval proceeds. Very informative and helpful for … [Read more...] about Science, Kansas and the Wizard of Washington
Science, Kansas and Pancakes
A long time ago, following work on the Restoration of Study 329, I was approached by Peter Goetzsche, featured above, to work on restoring the two trials that had got Prozac (fluoxetine) approved for children for depression. I may have suggested this idea to Peter in that from 2004 or so I was aware that reviewers in the US FDA had concluded that although they were going to … [Read more...] about Science, Kansas and Pancakes
PSSD Patients Needed for Small Fibre Neuropathy Investigation
We recently ran a couple of blog posts about the possibility of a link between post-SSRI sexual dysfunction (PSSD) and small fibre neuropathy: Sensory Receptors, Small Fibres and Neuropathy Antidepressant Neuropathy and the Color of Life The posts recapped some of the things we had previously discussed on the blog and also included new information about a Finnish … [Read more...] about PSSD Patients Needed for Small Fibre Neuropathy Investigation
Antidepressant Neuropathy and the Color of Life
Illustration: Is There Life After Meds?, © 2014 created by Billiam James Here is a Question put to the recent RxISK post on Sensory Neuropathy. I’m a psychologist and I have made numerous attempts to discontinue antidepressants only to experience significant withdrawal symptoms. I’ve been on antidepressants for 25 years at this point and have made four unsuccessful attempts … [Read more...] about Antidepressant Neuropathy and the Color of Life
Antidepressants and Premature Death
An article appeared in the British Journal of Psychiatry some weeks ago, by Narinder Bansal and colleagues from Bristol University. Having met Narinder I can tell readers she is a very impressive woman, with an impressive husband, Petros, who are both in one way or another working on population health. She had been working in cardiovascular medicine but switched to … [Read more...] about Antidepressants and Premature Death
Sensory Receptors, Small Fibres and Neuropathy
RxISK began in 2012. One of its main goals was to offer people an opportunity to report problems they had on treatments – any treatment – and generate a report they could take to a doctor in the hope this might get the doctor to take their problem seriously. I had seen my first cases of Post-SSRI Sexual Dysfunction (PSSD) in 2000, had been writing about withdrawal since the … [Read more...] about Sensory Receptors, Small Fibres and Neuropathy
Marilyn Lemak: Trial or Clemency?
A few weeks ago, an original set of four posts about Marilyn Lemak - Trial and Punishment, Then and Now, Clemency, When the Music Stops elicited mostly supportive comments from those who comment regularly on RxISK. The three posts last week, Eric Zorn and Marilyn Lemak, People Respond and Janet Lagerloef responds, drew a very different kind of response. There was a lot of … [Read more...] about Marilyn Lemak: Trial or Clemency?